-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-adults_executive.pdf
August 01, 2012 - Food
and Drug Administration (FDA). … contrast to previous
reviews, this CER focuses on comparisons of individual
medications rather than drug … • Drug dosage.
• Followup period. … National
Library of Medicine’s TOXLINE® and the MedEffect™
Canada Adverse Drug Reaction Database. … In vivo actions of atypical antipsychotic
drug on serotonergic and dopaminergic systems.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/gout_clinician.pdf
January 01, 2017 - overall adverse events ���
Subgroup of 1 RCT 2269 Age and race do not affect the efficacy of either drug … include toxic epidermal necrolysis (TEN), Stevens-Johnson syndrome (SJS), bone
marrow suppression, and drug
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-cancer-liver-metastases-therapies_research-protocol.pdf
September 27, 2012 - Tumor ischemia
raises the drug concentration, extends the retention of the chemotherapeutic agent, … most of their blood supply via the hepatic artery and the high first-
passage effect (a phenomenon of drug … doxorubicin into the tumor, allowing a longer intratumoral
exposure and less systemic exposure to the drug … "Chemoembolization, Therapeutic"[Mesh] OR "Radiotherapy"[Mesh] OR "radiotherapy
"[Subheading] OR "drug … Food and Drug Administration Web site, and relevant conference abstracts (from conferences
identified
-
effectivehealthcare.ahrq.gov/sites/default/files/06_devdelays_autism_potential_high_impact_june_2012.pdf
January 01, 2012 - similar drugs in the same class are read separately), and then topics in the same class of a
device, drug
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/psoriasis-chronic_executive.pdf
November 01, 2012 - etanercept, and adalimumab), and
one anti-IL 12/23 agent (ustekinumab) have approval
from the Food and Drug … agents concluded a difference in efficacy, suggesting
heterogeneity within the class and indicating drug … and therefore do not make between-class
comparisons, rather limit comparisons with the individual
drug … systemic biologic
agents and systemic nonbiologic agents (between-class
comparisons on an individual drug … systemic biologic
agents and systemic nonbiologic agents (between-class
comparisons on an individual drug
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gaps-pain-management.pdf
January 01, 2023 - long-term treatment
duration, and make direct comparisons among
key interventions both within and across drug … • Studies on the effects of risk mitigation
strategies (use of naloxone, urine drug
screening, prescription … drug monitoring
programs, and abuse deterrent formulations)
on clinical outcomes
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/episodic-migraine-surveillance-report-1.pdf
June 01, 2022 - Systematic
Reviews, PsycINFO®, and Scopus from July 2020 to September 2021.We also searched Food
and Drug … From the previous report,
NSAIDs as a drug class,
compared with placebo,
resolved pain at 2 hours … Therapy]
24 exp Vomiting/dt [Drug Therapy]
25
(((drug* or agent* or medication*) adj3 (nausea or … Study to assess adverse events and
drug to drug interaction of oral tablet atogepant
http://dx.doi.org … Clin Drug Investig. 2021
Feb;41(2):119-32. doi: 10.1007/s40261-020-
00997-1. PMID: 33426614.
-
effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1512.pdf
December 01, 2015 - Recent marketing data collected by the FDA’s
Center for Drug Evaluation and Research indicates that … The drug potentially holds additional promise as an AUD therapy because its safety
profile is better … Hazardous
drinkers and drug users in HMO primary care:
prevalence, medical conditions, and costs. … Mobile medical applications: guidance for industry
and Food and Drug Administration staff. … Food and Drug Administration
(FDA); 2015 Feb 9. 44 p.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antidepressants-update_research-protocol.pdf
July 13, 2011 - , continuation phase) or recurrence (i.e.,
maintenance phase) when a patient
1) continues the drug … medications
with new formulations (such as an extended release formulation) are approved by the
Food and Drug … Administration (FDA) through an application called a supplemental new
drug application (sNDA). … interest is whether response or
remission can be maintained if patients who have responded to one drug … If fewer than three
head-to-head trials are available for any drug comparison, we will compute indirect
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0334_08-04-2010.pdf
January 01, 2010 - Misclassification of drug metabolizer status, along with
the possibility that it might result in excessive … or inadequate dosing, and selection of
alternate drug that proves to be less effective or to have more
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/opioid-chronic-pain-surveillance-report-2.pdf
April 01, 2022 - Drug Overdose/
25. or/17-24
26. risk$.ti,ab,kf.
A-4
27. … Drug Overdose/
27. or/17-26
28. Substance Abuse Detection/
29. … Drug Overdose/
25. or/17-24
26. risk$.ti,ab,kf.
27. … Drug Overdose/
27. or/17-26
28. Substance Abuse Detection/
29. … Measures of diagnostic accuracy
• Intermediate outcomes (e.g.,
pharmacokinetics/pharmacodynamics,
drug-drug
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children-update_research-protocol.pdf
December 04, 2015 - Trends in antipsychotic drug use by very young, privately
insured children. … Drug Safety. 2011 Aug 1;34(8):651-68. PMID: 21751826.
17. … CNS Neuro Dis Drug Tar. 2010 Mar;9(1):50-4. PMID:
20201815.
29. … Drug! FDA!status! Indications! Age!group!approved!for! Black!box!Warnings! … $drug$therapy.fs.$
!
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND__0399_01-07-2011.pdf
January 01, 2011 - brachytherapy, RE; D) liver-directed chemotherapy, including hepatic artery infusion
(HAI) chemotherapy, TACE, drug-eluting … brachytherapy, RE; D) liver-directed chemotherapy, including hepatic artery infusion
(HAI) chemotherapy, TACE, drug-eluting
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/episodic-migraine-surveillance-report-3.pdf
August 01, 2022 - We also searched Food and Drug Administration, ClinicalTrials.gov, Health Canada,
the United Kingdom … No change in
SOE for NSAIDs
as a drug class
KQ 2. NSAIDs:
Dexketoprofen trometamol
vs. … No change in
SOE for NSAIDs
as a drug class
KQ 2. Antiemetic:
Magnesium sulfate vs. … Therapy]
24 exp Vomiting/dt [Drug Therapy]
25
(((drug* or agent* or medication*) adj3 (nausea … Study to assess adverse events
and drug to drug interaction of oral tablet
atogepant and ubrogepant
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stones-protocol.pdf
September 24, 2024 - evidence to
recommend metabolic testing.5 In addition to increased fluid intake, ACP recommends empiric
drug … Food and Drug
Administration (FDA)-approved prescription and over-the-counter medications
(Appendix … Food and Drug Administration; HDI = United Nations Development Programme
Human Development Index; KQ … OR
lumasiran[tw] OR nedosiran[tw] OR penicillamine*[tw] OR
sevelamer[tw] OR febuxostat[tw])
Drug … intervention
textwords
#11 #9 OR #10 All drug interventions
#12 (“potassium citrate”[
-
effectivehealthcare.ahrq.gov/sites/default/files/developmental-delays-horizon-scan-high-impact-1506.pdf
December 01, 2015 - similar drugs in the same class are read separately), and then topics in the same class of a
device, drug … study examining metadoxine for treating adult ADHD; a similar
trial is also planned to study this drug
-
effectivehealthcare.ahrq.gov/sites/default/files/pregnancy-horizon-scan-high-impact-1412.pdf
December 01, 2014 - similar drugs in the same class are read separately), and then topics in the same class of a
device, drug … spontaneous preterm birth; interventions intended to target both
the pregnant woman and fetus (a drug
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-emergency_executive.pdf
November 01, 2012 - Food and Drug Administration
and that are used, often off label, for acute migraine. … Food and
Drug Administration documents related to the drugs of
interest were reviewed for additional … The Scientific
Resource Center contacted drug manufacturers to
request published and unpublished study … to the pain
intervention in order to specifically deal with side effects
are grouped with the main drug … Instead, we present a summary of drug-related
adverse effects by treatment arm that provides an overall
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/restless-legs_disposition-comments.pdf
November 27, 2012 - We are specific about
using the exact drug name for each drug and not using
interchangeably. … line 22: three dopamine agonists (pramapexole,
ropinirole, and rotigotine) and one anticonvulsant drug … On page 27, the authors say augmentation can occur
with long term treatment of drug. … Augmentation can also occur
when you first start taking the drug and is reason to change
medications … It is an egregious error that gabapentin and gabapentin enacarbil
are lumped together as a single drug
-
effectivehealthcare.ahrq.gov/sites/default/files/pregnancy-horizon-scan-high-impact-1306.pdf
June 11, 2013 - similar drugs in the same class are read separately), and then topics in the same class of a
device, drug … Results
The table below lists two topics for which (1) some human data were available for programs (no
drug … Food and Drug Administration (FDA) ruled recently that this intervention is
not subject to FDA approval … Food and Drug Administration stated it would not intervene to require
regulation of the machine.7 On … Obama
administration drops its appeal of Plan B
ruling, will widen access to drug.