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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_overview.pdf
    January 17, 2014 - conclusions on comparative effectiveness of oral diabetes agents were out of date due to a newly approved drug … class (SGLT-2 inhibitors) and new evidence on previously reviewed drug classes.
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-foot-ulcer-amputation-economics_research.pdf
    January 01, 2011 - With respect to drug costs, in thou- sands of U.S. dollars, the mean total cost of all medica- tions … With respect to drug costs, the mean total cost of all medications used by Medicare FFS benefi- ciaries … In this population, all Part D claims in the given year with a National Drug Code (NDC) corresponding … First, the annual total drug cost was defined as the sum of the ingredient cost, dispensing fee, sales … Among Diabetic Medicare Parts A and B FFS Beneficiaries With and Without LEA, 2006-2008 Average Drug
  3. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_executive.pdf
    June 01, 2011 - versus ACEIs or ARBs, and therefore the evidence to discern any differential effects between these drug … ACEI with lower rates of cough, this translates to a difference of 1.2 persistence with drug therapy, … ACEI renin inhibitor trials did not find a statistically significant persistence with drug therapy, and … Persistence with ACEIs and ARBs have similar rates of treatment adherence drug therapy/ based on pill … (2) Relative persistence with drug therapy across the different classes of drugs.
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-treatment-ssri_surveillance.pdf
    January 01, 2013 - Food and Drug Administration (FDA), Health Canada, and UK Medicines and Healthcare products Regulatory … would produce prima facie evidence that a conclusion was out of date, such as the withdrawal of a drug … from the market, a 3 black box warning) or the availability of a new drug within class (the … Overall, there is limited supportive evidence for any single augmenting drug or for switching to a … or treat*)).tw. 39 ((treat* or therapy or drug) adj4 (resist* or fail*)).tw. 40 27 or 28 or 29
  5. effectivehealthcare.ahrq.gov/products/opioid-use-disorder/research-protocol
    February 29, 2016 - associated with additional risks from the high addiction potential of heroin, lack of control over drug … Food and Drug Administrated (FDA) for treatment of this condition accompanied by various psychosocial … Pharmacoepidemiol Drug Saf. Dec 2009;18(12):1166-1175. Volkow ND. … America's Addiction to Opioids: Heroin and Prescription Drug Abuse. … Prescription Drug Abuse Subcommittee.
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/opioid-use-disorder_research-protocol.pdf
    February 24, 2016 - associated with additional risks from the high addiction potential of heroin, lack of control over drug … Food and Drug Administrated (FDA) for treatment of this condition accompanied by various psychosocial … Pharmacoepidemiol Drug Saf. Dec 2009;18(12):1166-1175. 7. Volkow ND. … America’s Addiction to Opioids: Heroin and Prescription Drug Abuse. … Prescription Drug Abuse Subcommittee.
  7. Diabetes Mellitus (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1506.pdf
    June 01, 2015 - Weight loss over 39 weeks depended on drug dose. … Food and Drug Administration). … Food and Drug Administration (FDA). … Food and Drug Administration (FDA); 2012 Nov 9. 63 p. … Food and Drug Administration (FDA).
  8. PEPTIC ULCER #11 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1412.pdf
    December 01, 2014 - Food and Drug Administration (FDA) approval was based reported that patients with SBS experienced a … Food and Drug Administration (FDA). FDA approves Gattex to treat short bowel syndrome. … Food and Drug Administration (FDA); 2012 Dec 21 [accessed 2013 Jun 05]. [2 p]. … Specialty drug list. [internet]. … Drug coverage guidelines search: Gattex. [internet].
  9. effectivehealthcare.ahrq.gov/products/antipsychotics-adults/research-protocol
    December 01, 2010 - Study inclusion in the CER will not be limited by drug dosage. … Food and Drug Administration (FDA). Comparators: Any commercially available FDA-approved SGA. … Drug dosage. Followup period. Previous exposure to antipsychotics. … All methods of drug delivery (e.g., tablet, liquid, injection) will be eligible. … (neuroleptic adj2 (agent* or drug*)).tw. 28. or/25-27 29.
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-fatigue_research-protocol.pdf
    May 01, 2014 - Food and Drug Administration (FDA) approved medications for the treatment of ME/CFS, but many have … Food and Drug Administration’s (FDS’s) patient-focused drug development initiative, treatments fell … Center for Drug Evaluation and Research. … Food and Drug Administration's (FDA's) Patient-Focused Drug Development Initiative. … Food and Drug Administration; 2013.
  11. effectivehealthcare.ahrq.gov/get-involved/nominated-topics/the-american-college-of-chest-physicians-accp-proposes-to-update-the-medical-therapies-section-of-2007-updated-publication-on-medical-therapies-for-pulmonary-arterial-hypertension-accp-evidence-based-clinical-practice-guideli
    January 01, 2007 - Appropriateness for EHC Program Does your question include a health care drug, intervention, device
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/arthritis-psoriatric_research-protocol.pdf
    December 06, 2010 - Evidence-based Practice Center Systematic Review Protocol Project Title: Comparative Effectiveness of Drug … Food and Drug Administration (FDA) to treat patients with PsA are adalimumab, etanercept, golimumab, … The first review did not include certolizumab pegol, golimumab, and tocilizumab drug therapies listed … KQ3: For patients with psoriatic arthritis, do drug therapies differ in harms, tolerability, adherence … Comparative Effectiveness of Drug Therapy for Rheumatoid Arthritis and Psoriatic Arthritis in Adults
  13. effectivehealthcare.ahrq.gov/products/childhood-depression/protocol
    August 24, 2018 - Reaction Reporting Systems"] or [mh Accidents] or accident*:ti,ab or [mh "Drug Toxicity"] or [mh "Drug … Allergies" OR DE "Drug Dependency" OR TX “drug effects” OR DE "Drug Sensitivity" OR TX harm* OR TX " … Reaction Reporting Systems” OR Accidents OR accident* OR “Drug Toxicity” OR “Drug Hypersensitivity” … Allergies" OR DE "Drug Dependency" OR TX “drug effects” OR DE "Drug Sensitivity" OR TX harm* OR TX " … Reaction Reporting Systems” OR Accidents OR accident* OR “Drug Toxicity” OR “Drug Hypersensitivity”
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-update_research-protocol.pdf
    May 07, 2010 - List of angiotensin converting enzyme inhibitors (ACEIs), with the U.S.Food and Drug Administration … X versus an ARB + drug X (e.g., losartan + hydrochlorothiazide [HCTZ] versus enalapril + HCTZ) … • We will exclude comparisons of an ACEI + drug X versus an ARB + drug Y (e.g., enalapril + manidipine … “ACE inhibitors” or unspecified “ARBs” vs. unspecified “ACEIs” - Include ACEI + drug X vs. … ARB + drug X (e.g., losartan + HCTZ vs. enalapril + HCTZ) - Exclude ACEI + drug X vs.
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-childhood-protocol.pdf
    August 06, 2018 - Reaction Reporting Systems"] or [mh Accidents] or accident*:ti,ab or [mh "Drug Toxicity"] or [mh "Drug … Allergies" OR DE "Drug Dependency" OR TX “drug effects” OR DE "Drug Sensitivity" OR TX harm* OR TX … Reaction Reporting Systems” OR Accidents OR accident* OR “Drug Toxicity” OR “Drug Hypersensitivity … Allergies" OR DE "Drug Dependency" OR TX “drug effects” OR DE "Drug Sensitivity" OR TX harm* OR TX … Reaction Reporting Systems” OR Accidents OR accident* OR “Drug Toxicity” OR “Drug Hypersensitivity
  16. effectivehealthcare.ahrq.gov/sites/default/files/toc.pdf
    January 01, 2007 - Designed Delays Versus Rigorous Pragmatic Trials: Lower Carat Gold Standards Can Produce Relevant Drug … Studying Prescription Drug Use and Outcomes with Medicaid Claims Data: Strengths, Limitations, and … Developing Indicators of Inpatient Adverse Drug Events Through Non-Linear Analysis Using Administrative … Evaluation and Overview of the National Electronic Injury Surveillance System- Cooperative Adverse Drug
  17. effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1512.pdf
    December 01, 2015 - similar drugs in the same class are read separately), and then topics in the same class of a device, drug … Biogen (Cambridge, MA) has advanced this candidate drug to phase III testing, despite initial analysis … to have antiamyloidogenic properties, and oral ibuprofen, a common nonsteroidal anti-inflammatory drug … the widely- used cough suppressant dextromethorphan with quinidine, a class Ia antiarrhythmic drug, … AVP-786’s mechanism of action is unknown, but developers designed the drug using deuterium-modified
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children_research-protocol.pdf
    June 04, 2010 - Food and Drug Administration (FDA). … antipsychotic drug. … All formulations of drug delivery (e.g., tablet, liquid, injectable) and doses are eligible. … dose of the same antipsychotic drug. … National Library of Medicine’s TOXLINE® and MedEffectTM Canada Adverse Drug Reaction Database.
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-208-bipolar-adults-disposition-comments.pdf
    August 07, 2018 - The Benefits do NOT, in ANY WAY, outweight the risks of this drug. … This drug is a health hazard. My husband is somehow still living proof of this. … Get this drug OFF of the market, thank you all very MUCH for NOTHING but MISERY. … His walking and cognitive skills are richly impaired...thanks to this drug. … regard for safety of drug efficacy, which was NEGATIVE int the extreme!!!!!!
  20. effectivehealthcare.ahrq.gov/products/antipsychotics-children/research-protocol
    June 04, 2010 - Food and Drug Administration (FDA). … antipsychotic drug. … All formulations of drug delivery (e.g., tablet, liquid, injectable) and doses are eligible. … antipsychotic drug, placebo, or a different dose of the same antipsychotic drug. … drug therapy.fs. randomly.ab. trial.ab. groups.ab.

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