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Total Results: 2,080 records

Showing results for "drug".

301. Finding Evidence for Comparing Medical Interventions (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-finding-evidence_methods.pdf
     January 01, 2011 - Reference bias in reports of drug trials. … Exp LIVER DISEASES/ci Drug terms AND Exp LIVER DISEASE/si subheadings linked to drug name Exp … DRUG NAMEadverse events, po, to Exp DRUG NAMEadverse events, to floating subheadings Drug terms … Drug terms AND (ae OR to OR co).fs. … terms AND exp DRUG TOXICITY/ Drug terms AND (exp ADVERSE DRUG REACTION/ OR Exp Side- Effect/ )

302. Addressing Knowledge Gaps in Type 2 Diabetes Therapeutics: Comparative Effectiveness and Safety of Oral Antidiabetic Drugs | Effective Health Care Program
     effectivehealthcare.ahrq.gov/products/diabetes-oral-drugs-safety-knowledge-gaps
     January 01, 2005 - Addressing Knowledge Gaps in Type 2 Diabetes Therapeutics: Comparative Effectiveness and Safety of Oral Antidiabetic Drugs Timeline January 01, 2005 Topic Initiated January 01, 2005 Research Report Addressing Knowledge Gaps in Type 2 Diabetes Therapeutics: C…

303. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_research-protocol.pdf
     December 06, 2010 - Evidence-based Practice Center Systematic Review Protocol Project Title: Comparative Effectiveness of Drug … Food and Drug Administration (FDA) for the treatment RA at the time of the first review. … The Key Questions (KQs) Question 1: For patients with RA, do drug therapies differ in their ability … Question 3: For patients with RA, do drug therapies differ in harms, tolerability, patient adherence … Food and Drug Administration (FDA).

304. PREGNANCY, INCLUDING PRETERM BIRTH #12 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pregnancy-horizon-scan-high-impact-1512.pdf
     November 01, 2016 - dysplasia in preterm infants, interventions intended to target both the pregnant woman and fetus (a drug … AbbVie expects to complete pivotal trials by November 2016 and then submit a new drug application. … Food and Drug Administration approves elagolix, third-party payers may decline to cover the drug … Experts also noted that patients may prefer this oral drug over injectable alternatives. … elagolix.16,21 4 Acceptance and adoption: Clinicians may be more likely to prescribe an oral drug

305. Comparative Effectiveness of Angiotensin Converting Enzyme Inhibitors (ACEIs), Angiotensin II Receptor Antagonists (ARBs), and Direct Renin Inhibitors for Treating Essential Hypertension – An Update of the 2007 Report | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/ace-inhibitor-arb-update/research-protocol
     May 07, 2010 - Food and Drug Administration (FDA) approval status and examples of significant warnings. … X versus an ARB + drug X (e.g., losartan + hydrochlorothiazide [HCTZ] versus enalapril + HCTZ). … We will exclude comparisons of an ACEI + drug X versus an ARB + drug Y (e.g., enalapril + manidipine … “ACE inhibitors” or unspecified “ARBs” vs. unspecified “ACEIs” - Include ACEI + drug X vs. … ARB + drug X (e.g., losartan + HCTZ vs. enalapril + HCTZ) - Exclude ACEI + drug X vs.

306. #14 SUBSTANCE ABUSE (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1412.pdf
     December 01, 2014 - Food and Drug Administration (FDA)-approved medication for reversing opioid overdose. … Food and Drug Administration (FDA) priority review for Evzio was based on evaluation of a series of … -based online aggregator of prescription-drug prices, lists retail prices for Evzio ranging from $588 … Food and Drug Administration (FDA), Center for Drug Evaluation and Research (CDER); 2014 Apr 3. … Food and Drug Administration (FDA); 2014 Apr 03 [accessed 2014 May 27]. [3 p].

307. Management of Primary Headache During Pregnancy | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/headaches-pregnancy/protocol
     November 12, 2019 - Other drug within class. … Same drug(s), different route, treatment duration, initiation time, or other aspect. … Other drug within class. … Same drug(s), different route, treatment duration, initiation time, or other aspect. … Curr Drug Metab. 2012 May 1;13(4):474-90. PMID: 22299823. 15. U.S. Food and Drug Administration.

308. Comparative Effectiveness of Medications in Patients with Epilepsy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_disposition-comments.pdf
     March 01, 2012 - All that can be said is that a particular drug or class of drug is effective in some patients and not … If the drug was working in the first place, why would the patient be put back on the old drug rather … class of drug on the epilepsy syndrome. … Therefore, when exploring this topic, concentration, drug-drug interactions, and the fact that phenytoin … the first drug prescribed for the patient.

309. Treatments for Seasonal Allergic Rhinitis | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/allergy-seasonal/research
     July 16, 2013 - Food and Drug Administration (FDA).

310. Osteoporosis-Bone-Fracture Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-bone-fracture_executive.pdf
     March 01, 2012 - Nevertheless, the drug is still widely prescribed. … , and single drug versus single drug comparisons for drugs within the same class and across classes … versus placebo, and comparisons of drug versus drug, for drugs within the same class and across classes … The Food and Drug Administration’s Osteoporosis Guidance Document: past, present, and future. … Rockville, MD: Food and Drug Administration, Division of Metabolic and Endocrine Drug Products; 1994

311. Prevention, Diagnosis, and Management of Opioids, Opioid Misuse and Opioid Use Disorder in Older Adults: Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/opioids-oa-protocol.pdf
     June 29, 2019 - metabolism, polypharmacy (resulting in drug-drug interactions), compromised respiration, hypogonadism … Adults: 2015 National Survey on Drug Use and Health. … High Prevalence of Drug-Drug Interactions in Primary Health Care is Caused by Prescriptions from other … Reducing the risk of adverse drug events in older adults. … Am J Drug Alcohol Abuse. 2015;41(6):508-518. 39.

312. Treatments for Adults with Schizophrenia: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/schizophrenia-adult_research-protocol.pdf
     September 23, 2016 - Drug Class Review of Atypical Antipsychotic Drugs; Update 3. … Portland, OR: Oregon Health & Science University Drug Effectiveness Review Project; 2010. 17. … Antipsychotic drug use and mortality in older adults with dementia. … Drug Class Review: Second Generation Antipsychotic Drugs. Final Report - Update 4. … Methods for the Drug Effectiveness Review Project. BMC Med Res Methodol. 2012;12(1):140. 34.

313. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/atypical-antipsychotics-off-label-update_disposition-comments.pdf
     September 01, 2011 - That raises the question: Why focus on off-label use since expanding FDA approval for an approved drug … We included studies comparing atypicals to other drug classes throughout the report. … Similarly, our summary table of benefits (Table 1) lists each drug seperately for each indication. … Pharmacoepidemiology and drug safety (2011) DOI: 10.1002/pds.2082 The study results indicated 75% … In addition, it shows a trend towards worsening psychosis with this drug.

314. Diabetes Mellitus (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1306.pdf
     January 01, 2016 - The drug/device has been approved in Europe. … Food and Drug Administration (FDA); 2012 Nov 9. 63 p. … Drug list search results: bydureon. [internet]. … FDA approves eye drug for diabetics. [internet]. … Drug formulary. [internet].

315. Diabetes Mellitus (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1312.pdf
     January 01, 2016 - Food and Drug Administration (FDA). … Food and Drug Administration (FDA). … Drug list search results: bydureon. [internet]. … FDA approves eye drug for diabetics. [internet]. … Drug formulary. [internet].

316. CER 215 Adverse Effects of Pharmacologic Treatments of Major Depression in Older Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-215-depression-older-adults-comments.pdf
     March 28, 2019 - The a priori determined unit of analysis was drug class. … In some instances, where only a single drug was represented in a class, we provide that drug name so … , not just by drug class vs. … When data for a single drug was available, the drug level comparison is presented (ex. duloxetine … In the “Discussion” chapter under “applicability” we have added “Resulting drug-drug interactions and

317. CER 215 Adverse Effects of Pharmacologic Treatments of Major Depression in Older Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-215-depression-older-adults-comments.pdf
     March 28, 2019 - The a priori determined unit of analysis was drug class. … In some instances, where only a single drug was represented in a class, we provide that drug name so … , not just by drug class vs. … When data for a single drug was available, the drug level comparison is presented (ex. duloxetine … In the “Discussion” chapter under “applicability” we have added “Resulting drug-drug interactions and

318. Diagnosis and Treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/chronic-fatigue/research-protocol
     May 01, 2014 - Food and Drug Administration (FDA) approved medications for the treatment of ME/CFS, but many have been … Food and Drug Administration’s (FDS’s) patient-focused drug development initiative, treatments fell into … PMID: 17559660 Center for Drug Evaluation and Research. … Food and Drug Administration's (FDA's) Patient-Focused Drug Development Initiative. … Food and Drug Administration; 2013.

319. For persons who present with acute cough illness (ACI), what is the comparative effectiveness of various interventions for reducing inappropriate antimicrobial use? | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/get-involved/nominated-topics/for-persons-who-present-with-acute-cough-illness-aci-what-is-the-comparative-effectiveness-of-various-interventions-for-reducing-inappropriate-antimicrobial-use
     April 12, 2012 - unnecessary antibiotic prescribing which will in turn reduce costs, time to return to work, adverse drug … Drug resistance, development of serious complications, mortality from any cause, side effects due to … duration of hospital stay Appropriateness for EHC Program Does your question include a health care drug

320. Attention Deficit Hyperactivity Disorder Medications and Risk of Serious Cardiovascular Disease in Children and Youth | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/adhd-heart-disease-adults/research
     November 01, 2011 - Food and Drug Administration (FDA) Adverse Event Reporting System data have raised concern that attention-deficit … Measurements Baseline and follow-up drug use was assessed from automated records of dispensed prescriptions