-
effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1312.pdf
October 01, 2014 - and is known to be a street drug of abuse. … Research suggests new drug targets for
depression. … Washington (DC): Drug
Enforcement Administration, U.S. … Food and Drug Administration (FDA).
Methscopolamine bromide. [internet]. … Food and Drug
Administration (FDA) [accessed 2013 Aug 19].
[2 p].
-
effectivehealthcare.ahrq.gov/sites/default/files/kravitz_eccs2012.pdf
January 01, 2012 - Food and Drug Administration opened the door in 1997 by
reinterpreting own rules. … (clinical) approaches
Slide 18: Policy
Approaches
• Improve the quality of the prescription drug … Slide 19: What Is
Being
Done
• Drug facts
box
o Presents evidence about the benefits and
-
effectivehealthcare.ahrq.gov/sites/default/files/08_functional_limitations_potential_high_impact_2012-12-10.pdf
January 01, 2012 - syringes of the drug at no cost. … MS drug under investigation after 11 deaths. In:
Drug Discovery & Development [internet]. … Specialty
pharmacy program drug list. … MAP Pharmaceuticals resubmits New Drug
Application to FDA for Levadex orally inhaled
migraine drug … Food and Drug Administration (FDA).
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/pneumonia-antibiotic-treatment_research-protocol.pdf
July 19, 2013 - dosing of antibiotics
has been associated with poorer clinical outcomes and increased incidences of drug … PK is the
study of the time course of drug absorption, distribution, metabolism, and excretion. … Antibiotics for which PK/PD measures could be used
Drug Class Drug Group Drug*
Aminoglycosides … Optimizing drug exposure to minimize selection of antibiotic
resistance. … Antimicrobial pharmacodynamics: critical interactions of 'bug and drug'.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0255_06-25-2010.pdf
January 01, 2010 - interventions (e.g., atherectomy, brachytherapy)
2) Patients undergoing PCI, with either bare metal or drug-eluting … intravascular
techniques with a literature sample that mirrors contemporary treatment practices (e.g., drug-eluting … patients with coronary artery disease and patients undergoing a PCI with either a bare
metal stent or a drug-eluting
-
effectivehealthcare.ahrq.gov/products/osteoarthritis-pain/research-protocol
August 05, 2010 - evidence that standard dosing as labeled or alternative dosage strategies, such as intermittent dosing and drug … Drug (any trade name)
Labeled indications
Dosing
Dose adjustments for special populations
Oral … will also include studies that report safety in patients with rheumatoid arthritis or were taking the drug … We will use relatively broad searches, combining terms for drug names with terms for relevant research … sources may include reference lists of review articles and unpublished materials from the US Food and Drug
-
effectivehealthcare.ahrq.gov/products/eccs-2006
September 30, 2006 - Communicating Harms and Benefits of Prescription Drugs to Health Care Consumers (Eisenberg Center Conference Series 2006)
Timeline
September 30, 2006
Topic Initiated
September 30, 2006
White Paper
Communicating Harms and Benefits of Prescription Drugs to Hea…
-
effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1506.pdf
June 01, 2015 - Experts deemed three topics as having high-impact potential: An oral drug for treating
patients with … Because it has been approved for treating plaque psoriasis, cost of the drug is available. … High cost could be prohibitive and limit patient
access to drug if third-party payers do not cover … The drug was administered in three loading doses as an IV infusion, 10
mg/kg, at baseline, 2 weeks, … Food and Drug Administration (FDA) approved secukinumab for
treating adults with moderate-to-severe
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_1-user-guide-to-ocer_130129.pdf
August 13, 2012 - submits an application to the FDA
for an “investigational new drug.” … in routine clinical care after the
drug is approved for marketing (phase 4). … Intervention What is the intervention of interest (e.g., a drug, device, procedure, or test)? … Coverage Which bisphosphonate drugs should be included on a drug formulary? … Pharmacoepidemiol Drug Saf. 2012 May; 21
Suppl 2:6-12.
12. Normand SL, McNeil BJ.
-
effectivehealthcare.ahrq.gov/products/diabetes-drugs-utilization
April 05, 2012 - Data Points #9: Utilization of antidiabetic drugs among Medicare beneficiaries with diabetes, 2006-2009
Timeline
April 04, 2012
Topic Initiated
April 05, 2012
Research Report
Data Points #9: Utilization of antidiabetic drugs among Medicare beneficiaries with…
-
effectivehealthcare.ahrq.gov/products/diabetes-oral-drugs-safety-knowledge-gaps
January 01, 2005 - Addressing Knowledge Gaps in Type 2 Diabetes Therapeutics: Comparative Effectiveness and Safety of Oral Antidiabetic Drugs
Timeline
January 01, 2005
Topic Initiated
January 01, 2005
Research Report
Addressing Knowledge Gaps in Type 2 Diabetes Therapeutics: C…
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/research-gaps-womens-health-22.pdf
April 01, 2022 - .................................................................................... 10
Long-Term Drug … Therapies and Drug Holidays for Osteoporosis Fracture Prevention ................................... … https://effectivehealthcare.ahrq.gov/products/infertility/research
11
Long-Term Drug Therapies … • This report was used to inform a NIH Pathways to
Prevention workshop, Appropriate Use of Drug … Key Findings
• Evidence on the effects of long-term osteoporosis
drug treatment and drug continuation
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-observational-studies_methods.pdf
June 01, 2010 - a class
switch to a different drug in the same class. … Food
and Drug Administration and the Center for Medicare and Medicaid Services. … Challenges and opportunities for
pharmacoepidemiology in drug-therapy decision
making. … Drug
Effectiveness Review Project. … Drug class review on the
triptans: Drug Effectiveness Review Project.
-
effectivehealthcare.ahrq.gov/products/chronic-pain-opioid-treatment/research-protocol
December 19, 2013 - harms (e.g., depression)
Exclude:
Intermediate outcomes (e.g., pharmacokinetics/pharmacodynamics, drug-drug … The DAWN Report: Highlights of the 2010 Drug Abuse Warning Network (DAWN) Findings on Drug-Related Emergency … Drug poisoning deaths in the United States, 1980-2008. NCHS Data Brief. 2011;81:1-8. … Opioid dose and drug-related mortality in patients with nonmalignant pain. … Food and Drug Administration.
-
effectivehealthcare.ahrq.gov/products/juvenile-arthritis-dmards/research-protocol
March 09, 2010 - Furthermore, there are a large number of DMARDs that cannot simply be grouped by drug class. … Failure with a drug in one particular class does not necessarily predict failure with another drug in … been available for much longer then the other DMARDs, so there is greater clinical experience with the drug … and the drug is relatively inexpensive. … corticosteroids and NSAIDs FDA approval status for JIA, and examples of significant warnings from the drug
-
effectivehealthcare.ahrq.gov/sites/default/files/diabetes-update-2015_executive.pdf
January 01, 2015 - Food and Drug Administration. … Food and Drug Administration. … Food and Drug Administration. … Food and Drug Administration. … Food and Drug Administration.
-
effectivehealthcare.ahrq.gov/get-involved/nominated-topics/does-the-use-of-cytochrome-p450-2c19-cyp2c19-testing-to-predict-response-to-clopidogrel-in-people-1-with-acute-coronary-syndrome-2-who-have-suffered-other-cardiovascular-disease-related-events-eg-ischemic-stroke-symptomatic-p
August 04, 2010 - Potential for 1) misinterpretation or misclassification of drug metabolizer status, along with the possibility … that it might result in excessive or inadequate dosing, and 2) selection of alternate drug that proves … Appropriateness for EHC Program
Does your question include a health care drug, intervention, device
-
effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1506.pdf
June 01, 2015 - Personalized drug therapy has traditionally lagged behind behavioral
therapy in this regard because … Biopharm Drug Dispos. 2003
Jan;24(1):37-43. Also available:
http://dx.doi.org/10.1002/bdd.336. … Drug Enforcement Administration. … Research suggests new drug targets for
depression. … Washington
(DC): Drug Enforcement Administration, U.S.
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_8-user-guide-to-ocer_130129.pdf
October 01, 2013 - Food and Drug Administration, Silver Spring, MD
Jodi B. … Food and Drug Administration
(FDA) has authority over the NDC codes. … and are responsible for processing
and paying prescription drug claims. … Pharmacoepidemiol Drug Saf. 2001
August;10(5):389-92.
20. … Pharmacoepidemiol Drug Saf. 2011
Nov;20(11):1199-209.
51.
-
effectivehealthcare.ahrq.gov/products/allergy-seasonal/research
July 16, 2013 - Food and Drug Administration (FDA).