-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-treatments-research-amended-protocol.pdf
January 09, 2020 - screening; (5) use of prescription drug monitoring program
data; (6) availability of close follow-up … screening
• Use of prescription drug monitoring program data
• Availability of close follow-up
• … And others
KQ 2: Any oral, injection, infusion, topical nonopioid abortive
drug, including:
• … Drug Healthc
Patient Saf. 2018;10:37-43. doi: 10.2147/DHPS.S151073. PMID: 29760569.
17. … Canadian Headache Society
Guideline: acute drug therapy for migraine headache.
-
effectivehealthcare.ahrq.gov/sites/default/files/dementia_horizon-scan-high_impact-1306-revised.pdf
July 09, 2013 - A new drug application for
flutemetamol was submitted to the U.S. … Food and Drug Administration (FDA) in January
2013. … Food and Drug administration (FDA) accepted a new drug application
for flutemetamol.16
The U.S. … methods have been used, including needleless syringes inserted into alternating nostrils, a nasal
drug … Food and Drug Administration (FDA); 2010
Dec 20. 86 p.
-
effectivehealthcare.ahrq.gov/sites/default/files/arthritis_hi_impact.pdf
January 01, 2014 - Ann
estimated 750,000 gout patients initiate uric acid-lowering drug therapy in the U.S. annually. … The drug is a genetically engineered form of recombinant porcine urate oxidase, an enzyme
not found … Key Expert Comments: Overall, experts thought that the drug might address the unmet
need for a … Nat Rev Drug Discov 2009 Sep;8(9):688.
PMID: 19721439
79. Helms S, Darbishire PL. … Positive phase III results for benlysta as lupus
drug. Immunotherapy 2009 Sep;1(5):729.
85.
-
effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1406.pdf
June 01, 2014 - Food and Drug Administration
(FDA) approval. … Food and Drug Administration (FDA). FDA
approves Gattex to treat short bowel syndrome. … Food and
Drug Administration (FDA); 2012 Dec 21
[accessed 2013 Jun 05]. [2 p]. … Aetna non-Medicare prescription drug plan:
Subject: Gattex (teduglutide). [internet]. … Specialty drug list. [internet].
-
effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1406.pdf
June 01, 2014 - Food and Drug Administration (FDA). … Drug Enforcement Administration. … Research suggests new drug targets for
depression. … Washington (DC): Drug
Enforcement Administration, U.S. … Food and Drug
Administration (FDA) [accessed 2013 Aug
19]. [2 p].
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/multiple-sclerosis_research-protocol.pdf
December 17, 2013 - Food and Drug Administration; IV =
intravenous; PRMS = primary progressive multiple sclerosis; RRMS … □ For studies that examined discontinuing DMT in patients taking
Natalizumab for purposes of drug … • What drug should I start with? … • When should I switch a patient to a new drug and what should that drug be? … MS/Drug Holiday:
Database: Ovid MEDLINE
Search Strategy:
------------------------------
---------
-
effectivehealthcare.ahrq.gov/sites/default/files/pregnancy-horizon-scan-high-impact-1506.pdf
November 01, 2016 - similar drugs in the same class are read separately), and then topics in the same class of a
device, drug … spontaneous
preterm birth, interventions intended to target both the pregnant woman and fetus (a drug … AbbVie expects to
complete the pivotal trials by November 2016 and is expected to submit a new drug … If
elagolix gains marketing approval, third-party payers may decline to cover the drug without
data … Experts also noted that patients may
prefer this oral drug over injectable alternatives.
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-238-cervical-ripening-appendix-e-1.xlsx
January 01, 2009 - Inpatient: After administration of the study drug a further minimum of 20 minutes or more of electronic … Outpatient: After administration of the study drug patients underwent 40 minutes of electronic fetal … After administration of study drug, all patients underwent continuous FHR monitoring for 3 hours. … There is no mention of fetal monitoring following the administration of the study drug. … Placebo (Provider NR)
-See protocol for intervention 1
NA NA All patients
Four hours after the drug
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND__0250_05-20-2010.pdf
January 01, 2010 - implanted cardioverters), procedures (cardioversion, surgical, ablation)
Comparator(s): Different drug
-
effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1512.pdf
December 01, 2015 - Food and Drug Administration (FDA) in the first half of
2016. … Afrezza is also listed as a tier 5 drug
in some state Medicare drug plan formularies, which is the … Food and Drug Administration (FDA);
2012 Aug 3 [accessed 2012 Jun 18]. [2 p]. … Food and
Drug Administration (FDA); 2014 Jun 27
[accessed 2015 Jan 23]. [5 p]. … Food and
Drug Administration (FDA); 2014 Jun 30
[accessed 2015 Feb 09]. [5 p].
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/juvenile-arthritis-dmards_overview.pdf
March 27, 2014 - Topic Coming Back CER 28 DMARDs in Children with JIA NSD _SJ Clean
…
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/opioid-treatments-chronic-pain-protocol.pdf
December 19, 2018 - Intermediate outcomes such as pharmacokinetic and pharmacodynamic measures,
drug-drug interaction markers … The DAWN Report: Highlights of the 2010 Drug Abuse Warning Network
(DAWN) findings on drug-related emergency … Drug Overdose/
25. or/17-24
26. risk$.ti,ab,kf.
27. … Drug Monitoring/
21. (urine adj7 (screen$ or test$ or detect$)).ti,ab,kf.
22. … Drug Overdose/
27. or/17-26
28. Substance Abuse Detection/
29.
-
effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1406.pdf
September 26, 2014 - The drug-device combination has been approved in Europe. … Food and Drug Administration (FDA). … Food and Drug Administration
(FDA); 2012 Nov 9. 63 p. … Food and Drug Administration (FDA). … Autoimmune Drug Focus; 2012 Oct 22.
1 p.
56.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain_executive.pdf
October 01, 2011 - Food and Drug Administration
(FDA) as pharmaceuticals, including
glucosamine and chondroitin.5 Opioid … We
used relatively broad searches, combining terms for
drug names with terms for relevant research designs … any blinded or
open, parallel, or crossover randomized controlled trial
that compared one included drug … At this
time, no drug or supplement is known to modify the
course of disease, though some data suggest … • The effects of alternative dosing strategies such as
intermittent dosing or drug holidays have not
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_disposition-comments.pdf
September 01, 2011 - Doses and routes for each drug are specified
in the evidence table for each study. … in the placebo arm patients is not always mentioned in the
text summarizing the findings for each drug … One patient experiences a hematoma occurring on
day 108 which was deemed unrelated to the study drug … I think the section
would be more readable and informative if it were structured by drug
class (e.g … At
the moment one has to go back and forth among drug paragraphs to
get some idea of the comparative
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0316_03-12-2009.pdf
January 01, 2009 - It can also be used to adjust anti-hypertensive drug therapy and reduce clinic visits
with patients. … Use of anti-hypertensive drug therapy
iv. BP control
3. … Use of anti-hypertensive drug therapy
iv. BP control
4.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveillance-report-2.xlsx
September 30, 2015 - the trial did not indicate clear differences between treatments for pain, functioning, depression, or drug … Excluded patients with history of psychosis
Substance use: Excluded patients with history of illicit drug … stroke, and intracranial hemorrhage), major depression, cancer, and those without previous related drug … applicable; NR = not reported; NRS = numeric rating scale; NSAID = non-steroidal anti-inflammatory drug … ; OAT = opioid agonist therapy; OR = odds ratio; OUD = opioid use disorder; PDMP = prescription drug
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-236-mental-health-pregnancy-evidence-summary.pdf
April 01, 2021 - more inclusive and
included studies with comparator arms comprising women with prior exposure to the
drug … Studies of multiple drug exposures presented results for each
exposure but did not always present results … separately for the women with multiple drug
exposures. … studies with overlapping arms, we were not able to attribute the effect
of the intervention to a single drug
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-194-evidence-summary-corticosteroids-asthma.pdf
October 01, 2017 - At least one LAMA has
gained Food and Drug Administration (FDA) approval for
the long-term maintenance … salmeterol,a vilanterol,a,c
LAMA Aclidinium, glycopyrrolate, tiotropium,a umeclidinium
FDA = Food and Drug … effectiveness is an important part of decision-
making, this report did not include harms associated
with drug
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-screening_executive.pdf
November 01, 2012 - The strongest risk factor for HCV
infection is injection drug use. … The prevalence of HCV
infection in injection drug users varies widely depending
on age, duration of … injection drug use, and other factors
(such as availability and use of needle exchange
programs).15 … Prevalences range from less than 50 percent
in more recent studies of younger injection drug users … Drug Alcohol Depend. 2009;105(1-2):160-3.
PMID: 19647375.
80.