-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/emt-naloxon_research-protocol.pdf
November 29, 2016 - Increases in Drug and Opioid Overdose
Deaths--United States, 2000-2014. … Drug Alcohol Depend. 2016 Jun 1;163:16-23. doi:
10.1016/j.drugalcdep.2016.02.042. … Food and Drug Administration;
2014. … Food and Drug
Administration; 2015. … Am Health Drug Benefits. 2015 Oct;8(6 Suppl 3):S51-63. PMID:
26629261.
30.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/mat-retention-strategies-rapid-review-1.pdf
August 01, 2020 - drug users: a
randomized controlled trial. … Drug
and alcohol dependence. 2015;147:122-9. … Drug and
opioid-involved overdose deaths—United
States, 2013–2017. … Int J Drug Policy. 2018;56:73-80.
doi:
https://dx.doi.org/10.1016/j.drugpo.2018.03.
012. … drug users: a
randomized controlled trial.
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effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1506.pdf
June 01, 2015 - FDA approves Qsymia, a weight-loss
drug. [internet]. … Food and Drug Administration (FDA); 2014 Dec
23 [accessed 2015 Feb 03]. [5 p]. … Ther Adv Drug Saf.
2013;4(4):171-81. … Novo Nordisk to promote drug to treat obesity in
United States. [internet]. … Medica 2015 comprehensive preferred drug list
(PDL).
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effectivehealthcare.ahrq.gov/products/pneumonia-antibiotic-treatment/research-protocol
July 19, 2013 - dosing of antibiotics has been associated with poorer clinical outcomes and increased incidences of drug … PK is the study of the time course of drug absorption, distribution, metabolism, and excretion. … Antibiotics for which PK/PD measures could be used
Drug Class
Drug Group
Drug*
*Drug names … Optimizing drug exposure to minimize selection of antibiotic resistance. … Antimicrobial pharmacodynamics: critical interactions of 'bug and drug'.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/ced%20-appendix-2.xlsx
October 12, 2022 - Application of CED to an on-label use of a drug or biological is contrary to the requirements of the … controlled trials (RTCs) and to incorporate real-world evidence (RWE) Exclude on-label use of Food and Drug … drugs and biologicals be excluded from CED restrictions Application of CED to an on-label use of a drug … Requirements for post-FDA-approval real-world evidence development that is based on coverage to label for any drug
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/survival-quality_research.pdf
April 01, 2013 - Food and Drug Administration
Silver Spring, MD
Lynne Wagner, Ph.D. … PFS - QOL association
Author,
Year
Cancer
Type Exp Drug vs. … Endpoints for assessing drug
activity in clinical trials. … Food and Drug
Administration between July 2005 and
December 2007. … Food and Drug Administration.
-
effectivehealthcare.ahrq.gov/sites/default/files/s66.pdf
October 01, 2007 - Reform of drug regulation—beyond an indepen-
dent drug-safety board. … The epidemiology of drug treatment failure in rheumatoid
arthritis. … Phar-
macoepidemiol Drug Saf. 2006;15:565–574.
20. Steiner JF, Earnest MA. … Coding accuracy of administra-
tive drug claims in the Ontario Drug Benefit database. … Trends in prescription drug expenditures by
Medicaid enrollees.
-
effectivehealthcare.ahrq.gov/sites/default/files/s158.pdf
October 01, 2007 - DrPH,*§¶ Jerry Avorn, MD,*
and Sebastian Schneeweiss, MD*�
Background: Nonexperimental studies of drug … effects in large
automated databases can provide timely assessment of real-life drug
use, but are prone … Paradoxical relations of drug
treatment with mortality in older persons. … Colorectal cancer after start of
nonsteroidal anti-inflammatory drug use. … Pharmacoepidemiol Drug Saf. 2006;15:291–303.
10. Angrist JD, Imbens GW, Rubin DB.
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effectivehealthcare.ahrq.gov/products/observational-research-scores/research
May 15, 2012 - If a patient has high cholesterol and is on other medications, then the potential for drug-drug interactions … For example, perhaps an adverse effect of a drug is only apparent when the drug is prescribed to people … Pharmacoepidemiol Drug Safety 2005;14(7):465-76. … Pharmacoepidemiol Drug Saf 2005;14:S21. … Pharmacoepidemiol Drug Saf 2006; 15(5): 291–303.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/insomnia_disposition-comments.pdf
December 30, 2015 - Once a
drug is out of patent there is no incentive to finance proper
modern studies. … We included any drug available in the United States if
there were eligible trials. … ‘As needed’ use made insomnia
WORSE on nights the drug was omitted. … on nights the drug is not
taken. … and the placebo group after drug
withdrawal.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-211-rheumatoid-arthritis-disposition-comments.pdf
December 20, 2018 - Disposition of Comments for CER 211: Drug Therapy for Early Rheumatoid Arthritis: A Systematic Review … Drug Therapy for
Early Rheumatoid Arthritis: A Systematic Review Update. … Drug Therapy for
Rheumatoid Arthritis in Adults: An Update. … This should be revised to read the correct drug. … Additionally, drug classes were not
used as part of the search string.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/suda-final-protocol.pdf
October 02, 2018 - Drug use and sexually transmitted diseases among
female and male arrested youths. … drug use. … Drug Overdose Deaths among Adolescents Aged 15-
19 in the United States: 1999-2015. … SBIRT for adolescent drug and alcohol use:
current status and future directions. … National Institute on Drug Abuse.
-
effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1512.pdf
December 01, 2015 - similar drugs in the same class are read separately), and then topics in the same class of a
device, drug … Biogen (Cambridge, MA) has advanced this candidate
drug to phase III testing, despite initial analysis … to have antiamyloidogenic properties, and oral ibuprofen, a
common nonsteroidal anti-inflammatory drug … the widely-
used cough suppressant dextromethorphan with quinidine, a class Ia antiarrhythmic drug, … AVP-786’s mechanism of action is unknown, but developers
designed the drug using deuterium-modified
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effectivehealthcare.ahrq.gov/sites/default/files/09_infectiousdisease_potential_high_impact_june_2012.pdf
January 01, 2012 - coverage and formulary status of the drug on the
patient’s drug plan … Drug
coverage guidelines. [internet]. … Food and Drug
Administration (FDA); 2011 Apr 5. … Anthem Blue Cross California drug
list. … Drug list search results:
Dificid. [internet].
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/calcineurin-inhibitor_research-protocol.pdf
October 08, 2014 - These
patients present special challenges as there are drug-drug interactions between CNIs and protease … Studies that only evaluate drug pharmacokinetics will also
be excluded. … Ther Drug
Monit. 2009;31:139-52.
9. Bouamar R, Shuker N, Hesselink DA, et al. … Drug-drug interactions between
antiretroviral and immunosuppressive agents in
HIV-infected patients … monitoring
terms
'drug monitoring'/exp OR 'drug monitoring' OR ((drug OR therapy OR
therapeutic)
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-update_disposition-comments.pdf
December 01, 2011 - It would be better if it
could be divided into 2 reports - one way to do this would be drug
vs drug … Peer Reviewer #5 Methods Pg. 33, line 28 “…and drug interactions.” … 'Drug Interactions' is not really
an outcome measure. … or page 49, line 37-57
Direct evidence was considered sufficient to conduct meta-
analyses for six drug-drug … Might want to say that this is
probably only possible with this specific drug.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/opioid-treatments-chronic-pain-protocol.pdf
December 19, 2018 - Intermediate outcomes such as pharmacokinetic and pharmacodynamic measures,
drug-drug interaction markers … The DAWN Report: Highlights of the 2010 Drug Abuse Warning Network
(DAWN) findings on drug-related emergency … Drug Overdose/
25. or/17-24
26. risk$.ti,ab,kf.
27. … Drug Monitoring/
21. (urine adj7 (screen$ or test$ or detect$)).ti,ab,kf.
22. … Drug Overdose/
27. or/17-26
28. Substance Abuse Detection/
29.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/deprescribing-protocol.pdf
July 01, 2023 - polypharmacy3 and 58% to PIMs.4 Of concern, both polypharmacy and PIMs are associated with
adverse drug … potential to improve multiple aspects of patient safety and quality of care,
including by reducing drug … Adverse drug events in ambulatory care. … Clarifying adverse drug events: a clinician's guide to
terminology, documentation, and reporting. … Reducing Adverse Drug Events in Older Adults.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/insomnia_clinician.pdf
August 01, 2017 - Food and Drug Administration (FDA) has
approved several prescription drugs for insomnia, typically … Drug
General Adult Population Adults 55 Years of Age and Older
Global Outcomes Sleep Outcomesa Global … Food and Drug Administration
(FDA) for insomnia.
d Other benzodiazepines include drugs approved by … Food and Drug Administration Label Information
Drug Class Drug Common Effectsa Serious Effectsb
Nonbenzo … insomnia, nausea
�� Potential impairment of activities requiring complete mental
alertness after drug
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effectivehealthcare.ahrq.gov/products/urinary-incontinence-treatment/research
April 09, 2012 - Data Sources
We searched major electronic bibliographic databases, the FDA (Food and Drug Administration