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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/management-adhd-adults-protocol-amendment.pdf
    January 08, 2025 - Drug Alcohol Depend. 2010 Apr 1;108(1-2):130-3. doi: 10.1016/j.drugalcdep.2009.11.006. … Clin Drug Investig. 2014 Feb;34(2):147-57. doi: 10.1007/s40261-013-0156-z. PMID: 24297663. 32. … Pharmacoepidemiol Drug Saf. 2013 Sep;22(9):961-9. doi: 10.1002/pds.3473. PMID: 23813665. 109. … Food and Drug Administration RCT Randomized controlled trial VII. … Food and Drug Administration (FDA) of the U.S. Department of Health and Human Services.
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/management-adhd-adults-protocol.pdf
    June 10, 2024 - Drug Alcohol Depend. 2010 Apr 1;108(1-2):130-3. doi: 10.1016/j.drugalcdep.2009.11.006. … Clin Drug Investig. 2014 Feb;34(2):147-57. doi: 10.1007/s40261-013-0156-z. PMID: 24297663. 32. … Pharmacoepidemiol Drug Saf. 2013 Sep;22(9):961-9. doi: 10.1002/pds.3473. PMID: 23813665. 109. … Food and Drug Administration RCT Randomized controlled trial VII. … Food and Drug Administration (FDA) of the U.S. Department of Health and Human Services.
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_disposition-comments.pdf
    March 10, 2010 - Although any synthetic drug can be labeled "chemotherapy" in general, medical, and oncologic parlance … The statement that tamoxifen is the only drug evaluated in premenopausal women has been added to this … US, was minimally evaluated and the major study cited was stopped for an excess of strokes on the drug … Results I like the consistent presentation of results by drug (tam vs. ralox, tam vs. … We assumed that women take the drug for 5 years and NNT estimates were calculated for a 5-year period
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-foot-ulcer-amputation-economics_research.pdf
    January 01, 2011 - With respect to drug costs, in thou- sands of U.S. dollars, the mean total cost of all medica- tions … With respect to drug costs, the mean total cost of all medications used by Medicare FFS benefi- ciaries … In this population, all Part D claims in the given year with a National Drug Code (NDC) corresponding … First, the annual total drug cost was defined as the sum of the ingredient cost, dispensing fee, sales … Among Diabetic Medicare Parts A and B FFS Beneficiaries With and Without LEA, 2006-2008 Average Drug
  5. effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1406.pdf
    June 01, 2014 - This drug was approved for marketing in January 2012 and is now classified as diffused according to … Patients treated with the drug were reported to have a longer median time to the first exacerbation … about $44, so the drug would be relatively inexpensive for long-term, prophylactic use … could reduce the cost of the drug for patients who struggle with the cost of drug co- payments. … Food and Drug Administration (FDA) [accessed 2012 Jun 28]. [2 p].
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/opioid-use-disorder_research-protocol.pdf
    February 24, 2016 - associated with additional risks from the high addiction potential of heroin, lack of control over drug … Food and Drug Administrated (FDA) for treatment of this condition accompanied by various psychosocial … Pharmacoepidemiol Drug Saf. Dec 2009;18(12):1166-1175. 7. Volkow ND. … America’s Addiction to Opioids: Heroin and Prescription Drug Abuse. … Prescription Drug Abuse Subcommittee.
  7. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_executive.pdf
    June 01, 2011 - versus ACEIs or ARBs, and therefore the evidence to discern any differential effects between these drug … ACEI with lower rates of cough, this translates to a difference of 1.2 persistence with drug therapy, … ACEI renin inhibitor trials did not find a statistically significant persistence with drug therapy, and … Persistence with ACEIs and ARBs have similar rates of treatment adherence drug therapy/ based on pill … (2) Relative persistence with drug therapy across the different classes of drugs.
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/urinary-incontinence-treatment_executive.pdf
    April 01, 2012 - The drug needed to be given to eight older patients to achieve more than a 50 percent reduction in … Observational economic drug evaluations29,30 have demonstrated greater absolute rates of treatment … We concluded that there was a low risk of bias in the drug studies. … and nonpharmacological treatment modalities are superior to mono-drug therapy. … Drug Saf. 2001;24(9):703-13. PMID 11522122. 25. Wang PS, Levin R, Zhao SZ, et al.
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/deprescribing-protocol.pdf
    July 01, 2023 - polypharmacy3 and 58% to PIMs.4 Of concern, both polypharmacy and PIMs are associated with adverse drug … potential to improve multiple aspects of patient safety and quality of care, including by reducing drug … Adverse drug events in ambulatory care. … Clarifying adverse drug events: a clinician's guide to terminology, documentation, and reporting. … Reducing Adverse Drug Events in Older Adults.
  10. effectivehealthcare.ahrq.gov/sites/default/files/ch_8-user-guide-to-ocer_130129.pdf
    October 01, 2013 - Food and Drug Administration, Silver Spring, MD Jodi B. … Food and Drug Administration (FDA) has authority over the NDC codes. … and are responsible for processing and paying prescription drug claims. … Pharmacoepidemiol Drug Saf. 2001 August;10(5):389-92. 20. … Pharmacoepidemiol Drug Saf. 2011 Nov;20(11):1199-209. 51.
  11. Ced-Appendix-3 (xls file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/ced-appendix-3.xlsx
    June 24, 2022 - Innovative Medicine Fund (UK) 14 National Insitute for Health and Care Excellence (NICE) Cancer Drug … Pharmacoepidemiol Drug Saf. 2017 Sep;26(9):1018-32. doi: 10.1002/pds.4295. PMID: 28913963. … and Biological Products Guidance for Industry US Food & Drug Administration. … and Biological Products US Food & Drug Administration. … and Biological Products US Food & Drug Administration.
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-childhood-protocol.pdf
    August 06, 2018 - Reaction Reporting Systems"] or [mh Accidents] or accident*:ti,ab or [mh "Drug Toxicity"] or [mh "Drug … Allergies" OR DE "Drug Dependency" OR TX “drug effects” OR DE "Drug Sensitivity" OR TX harm* OR TX … Reaction Reporting Systems” OR Accidents OR accident* OR “Drug Toxicity” OR “Drug Hypersensitivity … Allergies" OR DE "Drug Dependency" OR TX “drug effects” OR DE "Drug Sensitivity" OR TX harm* OR TX … Reaction Reporting Systems” OR Accidents OR accident* OR “Drug Toxicity” OR “Drug Hypersensitivity
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/psoriasis-chronic_disposition-comments.pdf
    November 27, 2012 - Food and Drug Administration (FDA) can be included as per AHRQ. … Alefacept is no longer available; Astellas pulled the drug from the market in December 2011. … Although alefacept was voluntarily withdrawn from the market by the manufacturer this year, the drug … For inclusion/exclusion criteria, were data obtained from drug manufacturers? … Food and Drug Administration (FDA) for psoriasis treatment.”
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-update_research-protocol.pdf
    May 07, 2010 - List of angiotensin converting enzyme inhibitors (ACEIs), with the U.S.Food and Drug Administration … X versus an ARB + drug X (e.g., losartan + hydrochlorothiazide [HCTZ] versus enalapril + HCTZ) … • We will exclude comparisons of an ACEI + drug X versus an ARB + drug Y (e.g., enalapril + manidipine … “ACE inhibitors” or unspecified “ARBs” vs. unspecified “ACEIs” - Include ACEI + drug X vs. … ARB + drug X (e.g., losartan + HCTZ vs. enalapril + HCTZ) - Exclude ACEI + drug X vs.
  15. effectivehealthcare.ahrq.gov/products/dietary-supplements/research
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-finding-evidence_methods.pdf
    January 01, 2011 - Reference bias in reports of drug trials. … Exp LIVER DISEASES/ci Drug terms AND Exp LIVER DISEASE/si subheadings linked to drug name Exp … DRUG NAMEadverse events, po, to Exp DRUG NAMEadverse events, to floating subheadings Drug terms … Drug terms AND (ae OR to OR co).fs. … terms AND exp DRUG TOXICITY/ Drug terms AND (exp ADVERSE DRUG REACTION/ OR Exp Side- Effect/ )
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ahrq-healthcare-horizon-scan-protocol-operations-manual-151001.pdf
    September 01, 2015 - Is it a generic drug? If so, do not select, because these are “me-too” of existing drugs. c. … Does this appear to be a different/off-label use of an available drug, biologic, or device? … Is this a different delivery mode for an existing drug or device? … Food and Drug Administration [FDA] approved) and the specific clinical indication for which they are … Designation Database 12 A database of drugs that have received orphan drug status.
  18. effectivehealthcare.ahrq.gov/sites/default/files/ahrq-healthcare-horizon-scan-protocol-operations-manual-151001.pdf
    September 01, 2015 - Is it a generic drug? If so, do not select, because these are “me-too” of existing drugs. c. … Does this appear to be a different/off-label use of an available drug, biologic, or device? … Is this a different delivery mode for an existing drug or device? … Food and Drug Administration [FDA] approved) and the specific clinical indication for which they are … Designation Database 12 A database of drugs that have received orphan drug status.
  19. effectivehealthcare.ahrq.gov/sites/default/files/06_devdelays_potential_high_impact_2012-12-10.pdf
    January 01, 2012 - similar drugs in the same class are read separately), and then topics in the same class of a device, drug … This drug is being investigated for off-label use.
  20. effectivehealthcare.ahrq.gov/sites/default/files/cer-239-acute-migraine-evidence-summary.pdf
    December 01, 2020 - Drug Healthc Patient Saf. 2018;10:37-43. doi: 10.2147/DHPS.S151073. PMID: 29760569. 13.

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