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Total Results: 1,546 records

Showing results for "drug".

241. medication-assisted-treatment-protocol-160224 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/opioid-use-disorder_research-protocol.pdf
     February 24, 2016 - associated with additional risks from the high addiction potential of heroin, lack of control over drug … Food and Drug Administrated (FDA) for treatment of this condition accompanied by various psychosocial … Pharmacoepidemiol Drug Saf. Dec 2009;18(12):1166-1175. 7. Volkow ND. … America’s Addiction to Opioids: Heroin and Prescription Drug Abuse. … Prescription Drug Abuse Subcommittee.

242. PEPTIC ULCER #11 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pepticulcer_hi_impact.pdf
     January 01, 2012 - In 2001, teduglutide received orphan drug designation for treatment of SBS. … In August 2011, NPS began submitting data for a new drug application to FDA for the same indication … Additional, less salient considerations included potential drug-drug interactions, the possibility … The drug is also expected to be widely accepted by patients. … Food and Drug Administration (FDA); 2009 Oct 2 [accessed 2011 Feb 14]. [2 p].

243. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_executive.pdf
     June 01, 2011 - versus ACEIs or ARBs, and therefore the evidence to discern any differential effects between these drug … ACEI with lower rates of cough, this translates to a difference of 1.2 persistence with drug therapy, … ACEI renin inhibitor trials did not find a statistically significant persistence with drug therapy, and … Persistence with ACEIs and ARBs have similar rates of treatment adherence drug therapy/ based on pill … (2) Relative persistence with drug therapy across the different classes of drugs.

244. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/management-adhd-adults-protocol-amendment.pdf
     January 08, 2025 - Drug Alcohol Depend. 2010 Apr 1;108(1-2):130-3. doi: 10.1016/j.drugalcdep.2009.11.006. … Clin Drug Investig. 2014 Feb;34(2):147-57. doi: 10.1007/s40261-013-0156-z. PMID: 24297663. 32. … Pharmacoepidemiol Drug Saf. 2013 Sep;22(9):961-9. doi: 10.1002/pds.3473. PMID: 23813665. 109. … Food and Drug Administration RCT Randomized controlled trial VII. … Food and Drug Administration (FDA) of the U.S. Department of Health and Human Services.

245. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/management-adhd-adults-protocol.pdf
     June 10, 2024 - Drug Alcohol Depend. 2010 Apr 1;108(1-2):130-3. doi: 10.1016/j.drugalcdep.2009.11.006. … Clin Drug Investig. 2014 Feb;34(2):147-57. doi: 10.1007/s40261-013-0156-z. PMID: 24297663. 32. … Pharmacoepidemiol Drug Saf. 2013 Sep;22(9):961-9. doi: 10.1002/pds.3473. PMID: 23813665. 109. … Food and Drug Administration RCT Randomized controlled trial VII. … Food and Drug Administration (FDA) of the U.S. Department of Health and Human Services.

246. DEcIDE 33: Summary Variables in Observational Resesarch: Propensity Scores and Disease Risk Scores (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/observational-research-scores_research.pdf
     May 01, 2012 - If a patient has high cholesterol and is on other medications, then the potential for drug-drug interactions … For example, perhaps an adverse effect of a drug is only apparent when the drug is prescribed to people … Pharmacoepidemiol Drug Saf 2005;14:S22- 3. 16. … Pharmacoepidemiol Drug Safety 2005;14(7):465-76. … Pharmacoepidemiol Drug Saf 2005;14:S21.

247. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_disposition-comments.pdf
     March 10, 2010 - Although any synthetic drug can be labeled "chemotherapy" in general, medical, and oncologic parlance … The statement that tamoxifen is the only drug evaluated in premenopausal women has been added to this … US, was minimally evaluated and the major study cited was stopped for an excess of strokes on the drug … Results I like the consistent presentation of results by drug (tam vs. ralox, tam vs. … We assumed that women take the drug for 5 years and NNT estimates were calculated for a 5-year period

248. AHRQ Evidence-based Practice Center Program Research Gaps Summary: Primary Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/research-gap-primary-care-summary-table.pdf
     March 01, 2022 - Therapy and Drug Holidays for Osteoporosis Fracture Prevention: A Systematic Review ................ … Food and Drug Administration warrants further research and ongoing post marketing surveillance. …  Motivational interviewing decreases combined alcohol and other drug use. … treatment and of osteoporosis drug treatment discontinuation and holidays. … Key Messages • Evidence on the effects of long-term osteoporosis drug treatment and drug continuation

249. EHC Protocol: Making Healthcare Safer IV: Deprescribing to Reduce Medication Harms in Older Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/deprescribing-protocol.pdf
     July 01, 2023 - polypharmacy3 and 58% to PIMs.4 Of concern, both polypharmacy and PIMs are associated with adverse drug … potential to improve multiple aspects of patient safety and quality of care, including by reducing drug … Adverse drug events in ambulatory care. … Clarifying adverse drug events: a clinician's guide to terminology, documentation, and reporting. … Reducing Adverse Drug Events in Older Adults.

250. Urinary-Incontinence-Treatment Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/urinary-incontinence-treatment_executive.pdf
     April 01, 2012 - The drug needed to be given to eight older patients to achieve more than a 50 percent reduction in … Observational economic drug evaluations29,30 have demonstrated greater absolute rates of treatment … We concluded that there was a low risk of bias in the drug studies. … and nonpharmacological treatment modalities are superior to mono-drug therapy. … Drug Saf. 2001;24(9):703-13. PMID 11522122. 25. Wang PS, Levin R, Zhao SZ, et al.

251. Ced-Appendix-3 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ced-appendix-3.xlsx
     June 24, 2022 - Innovative Medicine Fund (UK) 14 National Insitute for Health and Care Excellence (NICE) Cancer Drug … Pharmacoepidemiol Drug Saf. 2017 Sep;26(9):1018-32. doi: 10.1002/pds.4295. PMID: 28913963. … and Biological Products Guidance for Industry US Food & Drug Administration. … and Biological Products US Food & Drug Administration. … and Biological Products US Food & Drug Administration.

252. Evidence-based Practice Center Systematic Review Protocol: Depression in Children: Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-childhood-protocol.pdf
     August 06, 2018 - Reaction Reporting Systems"] or [mh Accidents] or accident*:ti,ab or [mh "Drug Toxicity"] or [mh "Drug … Allergies" OR DE "Drug Dependency" OR TX “drug effects” OR DE "Drug Sensitivity" OR TX harm* OR TX … Reaction Reporting Systems” OR Accidents OR accident* OR “Drug Toxicity” OR “Drug Hypersensitivity … Allergies" OR DE "Drug Dependency" OR TX “drug effects” OR DE "Drug Sensitivity" OR TX harm* OR TX … Reaction Reporting Systems” OR Accidents OR accident* OR “Drug Toxicity” OR “Drug Hypersensitivity

253. Ch 8-User-Guide-To-Ocer 130129 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/ch_8-user-guide-to-ocer_130129.pdf
     October 01, 2013 - Food and Drug Administration, Silver Spring, MD Jodi B. … Food and Drug Administration (FDA) has authority over the NDC codes. … and are responsible for processing and paying prescription drug claims. … Pharmacoepidemiol Drug Saf. 2001 August;10(5):389-92. 20. … Pharmacoepidemiol Drug Saf. 2011 Nov;20(11):1199-209. 51.

254. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-update_research-protocol.pdf
     May 07, 2010 - List of angiotensin converting enzyme inhibitors (ACEIs), with the U.S.Food and Drug Administration … X versus an ARB + drug X (e.g., losartan + hydrochlorothiazide [HCTZ] versus enalapril + HCTZ) … • We will exclude comparisons of an ACEI + drug X versus an ARB + drug Y (e.g., enalapril + manidipine … “ACE inhibitors” or unspecified “ARBs” vs. unspecified “ACEIs” - Include ACEI + drug X vs. … ARB + drug X (e.g., losartan + HCTZ vs. enalapril + HCTZ) - Exclude ACEI + drug X vs.

255. Disposition of Comments Report for Biologic and Nonbiologic Systemic Agents and Phottherapy for Treatment of Chronic Plaque Psoriasis (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/psoriasis-chronic_disposition-comments.pdf
     November 27, 2012 - Food and Drug Administration (FDA) can be included as per AHRQ. … Alefacept is no longer available; Astellas pulled the drug from the market in December 2011. … Although alefacept was voluntarily withdrawn from the market by the manufacturer this year, the drug … For inclusion/exclusion criteria, were data obtained from drug manufacturers? … Food and Drug Administration (FDA) for psoriasis treatment.”

256. Finding Evidence for Comparing Medical Interventions (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-finding-evidence_methods.pdf
     January 01, 2011 - Reference bias in reports of drug trials. … Exp LIVER DISEASES/ci Drug terms AND Exp LIVER DISEASE/si subheadings linked to drug name Exp … DRUG NAMEadverse events, po, to Exp DRUG NAMEadverse events, to floating subheadings Drug terms … Drug terms AND (ae OR to OR co).fs. … terms AND exp DRUG TOXICITY/ Drug terms AND (exp ADVERSE DRUG REACTION/ OR Exp Side- Effect/ )

257. Horizon Scanning Protocol and Operations Manual September 2015 Revision (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ahrq-healthcare-horizon-scan-protocol-operations-manual-151001.pdf
     September 01, 2015 - Is it a generic drug? If so, do not select, because these are “me-too” of existing drugs. c. … Does this appear to be a different/off-label use of an available drug, biologic, or device? … Is this a different delivery mode for an existing drug or device? … Food and Drug Administration [FDA] approved) and the specific clinical indication for which they are … Designation Database 12 A database of drugs that have received orphan drug status.

258. Horizon Scanning Protocol and Operations Manual September 2015 Revision (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/ahrq-healthcare-horizon-scan-protocol-operations-manual-151001.pdf
     September 01, 2015 - Is it a generic drug? If so, do not select, because these are “me-too” of existing drugs. c. … Does this appear to be a different/off-label use of an available drug, biologic, or device? … Is this a different delivery mode for an existing drug or device? … Food and Drug Administration [FDA] approved) and the specific clinical indication for which they are … Designation Database 12 A database of drugs that have received orphan drug status.

259. #06 Developmental Delays ADHD, and Autism (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/06_devdelays_potential_high_impact_2012-12-10.pdf
     January 01, 2012 - similar drugs in the same class are read separately), and then topics in the same class of a device, drug … This drug is being investigated for off-label use.

260. Research Protocol for Interventions for Substance Use Disorders in Adolescents: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/suda-final-protocol.pdf
     October 02, 2018 - Drug use and sexually transmitted diseases among female and male arrested youths. … drug use. … Drug Overdose Deaths among Adolescents Aged 15- 19 in the United States: 1999-2015. … SBIRT for adolescent drug and alcohol use: current status and future directions. … National Institute on Drug Abuse.