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Total Results: 1,544 records

Showing results for "drug".

221. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0255_06-25-2010.pdf
     January 01, 2010 - interventions (e.g., atherectomy, brachytherapy) 2) Patients undergoing PCI, with either bare metal or drug-eluting … intravascular techniques with a literature sample that mirrors contemporary treatment practices (e.g., drug-eluting … patients with coronary artery disease and patients undergoing a PCI with either a bare metal stent or a drug-eluting

222. DEMENTIA INCLUDING ALZHEIMER'S #04 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/04_dementia_potential_high_impact_2012-12-10.pdf
     January 01, 2012 - similar drugs in the same class are read separately), and then topics in the same class of a device, drug … Currently, the beta-amyloid antibody drug class is being investigated for treating AD. … Food and Drug administration (FDA) for the agent in late 2012. … have been used for ensuring intranasal delivery, including needle-less nostril syringes, a nasal drug … Food and Drug Administration (FDA); 2010 Dec 20. 86 p.

223. pneumonia-antibiotic-treatment-protocol-130718 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/pneumonia-antibiotic-treatment_research-protocol.pdf
     July 19, 2013 - dosing of antibiotics has been associated with poorer clinical outcomes and increased incidences of drug … PK is the study of the time course of drug absorption, distribution, metabolism, and excretion. … Antibiotics for which PK/PD measures could be used Drug Class Drug Group Drug* Aminoglycosides … Optimizing drug exposure to minimize selection of antibiotic resistance. … Antimicrobial pharmacodynamics: critical interactions of 'bug and drug'.

224. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-off-label-update_research-protocol.pdf
     May 19, 2010 - Objectives for the Systematic Review Atypical antipsychotics are approved by the United States Food and Drug … To arrive at a quantitative measure, we will use the Jadad scale, which was developed for drug trials2 … The evidence of risks (adverse events) will be summarized within drug (each atypical antipsychotic separately … severely symptomatic persons have higher scores, a negative effect size indicates that the atypical drug

225. Monitoring-Programs-Rapid-Research-Appendix-C (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/monitoring-programs-rapid-research-appendix-c.xlsx
     May 31, 2025 - strategies in a shortage response can promote improved patient care and advancement of the profession Drug … data inventory, projection, predictive and real-time supply chain availability/sourcing technology for drug … cost containment, and research 4) Enhanced pharmacist autonomy 5) Existing infrastructure (technology; drug … Effective, regular communication between key teams and personnel and to staff 8) Early communication with drug … Food and Drug Administration; GPS = global positioning software; HIT = health information technology;

226. Topic-Brief3-Sud (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/topic-brief3-SUD.pdf
     April 01, 2021 - Pain perception in drug-free and in methadone-maintained human ex- addicts. … Drug overdose deaths in the United States, 1999– 2018. NCHS Data Brief No. 356. … Drug Alcohol Depend. 2018 Dec 1;193:142-7. doi: 10.1016/j.drugalcdep.2018.10.002. … Drug Alcohol Depend. 2004 Jan 7;73(1):23-31. doi: 10.1016/j.drugalcdep.2003.08.007. … Drug and alcohol dependence. 2019;203:61-5. PMID: CN-01978075. 50.

227. Topic-Brief3-Sud (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-brief3-SUD.pdf
     April 01, 2021 - Pain perception in drug-free and in methadone-maintained human ex- addicts. … Drug overdose deaths in the United States, 1999– 2018. NCHS Data Brief No. 356. … Drug Alcohol Depend. 2018 Dec 1;193:142-7. doi: 10.1016/j.drugalcdep.2018.10.002. … Drug Alcohol Depend. 2004 Jan 7;73(1):23-31. doi: 10.1016/j.drugalcdep.2003.08.007. … Drug and alcohol dependence. 2019;203:61-5. PMID: CN-01978075. 50.

228. #05 DEPRESSION (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1312.pdf
     October 01, 2014 - and is known to be a street drug of abuse. … Research suggests new drug targets for depression. … Washington (DC): Drug Enforcement Administration, U.S. … Food and Drug Administration (FDA). Methscopolamine bromide. [internet]. … Food and Drug Administration (FDA) [accessed 2013 Aug 19]. [2 p].

229. Disposition of Comments for CER 208 Treatment for Bipolar Disorder in Adults A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-208-bipolar-adults-disposition-comments.pdf
     August 07, 2018 - The Benefits do NOT, in ANY WAY, outweight the risks of this drug. … This drug is a health hazard. My husband is somehow still living proof of this. … Get this drug OFF of the market, thank you all very MUCH for NOTHING but MISERY. … His walking and cognitive skills are richly impaired...thanks to this drug. … regard for safety of drug efficacy, which was NEGATIVE int the extreme!!!!!!

230. CER 229 Evidence Summary: Opioid Treatments for Chronic Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-229-opioid-treatments-chronic-pain-evidence-summary.pdf
     April 01, 2020 - Annual Surveillance Report of Drug-Related Risks and Outcomes--United States, 2017. … Drug Abuse Warning Network. … The DAWN Report: Highlights of the 2010 Drug Abuse Warning Network (DAWN) findings on drug-related … Drug Alcohol Depend. 2015 Jun 01;151:47-55. doi: 10.1016/j. drugalcdep.2015.02.033. … Food & Drug Administration, Drug Safety Communications; 2019.

231. Treatments for Schizophrenia in Adults: A Systematic (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/executive-summary-2017-schizophrenia-adult.pdf
     January 01, 2017 - Both groups (treatment and usual care) received usual care, including drug treatment throughout the … Randomized controlled trials were evaluated with criteria developed by the Drug Effectiveness Review … Overall, no drug intervention had high-strength evidence for any outcome of interest, but we found … Among illicit drug users, differences between older SGAs were not found in rate or time to drug discontinuation … Methods for the drug effectiveness review project.

232. DEMENTIA INCLUDING ALZHEIMER'S #04 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1512.pdf
     December 01, 2015 - similar drugs in the same class are read separately), and then topics in the same class of a device, drug … Biogen (Cambridge, MA) has advanced this candidate drug to phase III testing, despite initial analysis … to have antiamyloidogenic properties, and oral ibuprofen, a common nonsteroidal anti-inflammatory drug … the widely- used cough suppressant dextromethorphan with quinidine, a class Ia antiarrhythmic drug, … AVP-786’s mechanism of action is unknown, but developers designed the drug using deuterium-modified

233. DEMENTIA INCLUDING ALZHEIMER'S #04 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/04_dementia_potential_high_impact_june_2012.pdf
     January 01, 2012 - similar drugs in the same class are read separately), and then topics in the same class of a device, drug … Food and Drug administration (FDA) for the agent in late 2012. … have been used for ensuring intranasal delivery, including needle-less nostril syringes, a nasal drug … methods have been used, including needle-less syringes inserted into alternating nostrils, a nasal drug … Food and Drug Administration (FDA); 2010 Dec 20. 86 p.

234. Arthritis and Nontraumatic Joint Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1506.pdf
     June 01, 2015 - Experts deemed three topics as having high-impact potential: An oral drug for treating patients with … Because it has been approved for treating plaque psoriasis, cost of the drug is available. … High cost could be prohibitive and limit patient access to drug if third-party payers do not cover … The drug was administered in three loading doses as an IV infusion, 10 mg/kg, at baseline, 2 weeks, … Food and Drug Administration (FDA) approved secukinumab for treating adults with moderate-to-severe

235. Arthritis and Nontraumatic Joint Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1512.pdf
     December 29, 2015 - High treatment costs could limit patient access if third-party payers do not cover the drug. … High cost could limit patient access to the drug. … Some experts thought that as a new drug, lesinurad would be more expensive than existing options. … drug- name=tofacitinib. 69. Mayo Clinic staff. Rheumatoid arthritis. [internet]. … drug-name=tofacitinib http://www.goodrx.com/tofacitinib?

236. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-adults_research-protocol.pdf
     December 01, 2010 - recommends that selection of an antipsychotic should be based on a patient’s previous responses to the drug … Study inclusion in the CER will not be limited by drug dosage. 4. … Food and Drug Administration (FDA). Comparators: Any commercially available FDA-approved SGA. … All methods of drug delivery (e.g., tablet, liquid, injection) will be eligible. … (neuroleptic adj2 (agent* or drug*)).tw. 28. or/25-27 29.

237. PEPTIC ULCER #11 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pepticulcer_hi_impact.pdf
     January 01, 2012 - In 2001, teduglutide received orphan drug designation for treatment of SBS. … In August 2011, NPS began submitting data for a new drug application to FDA for the same indication … Additional, less salient considerations included potential drug-drug interactions, the possibility … The drug is also expected to be widely accepted by patients. … Food and Drug Administration (FDA); 2009 Oct 2 [accessed 2011 Feb 14]. [2 p].

238. DEcIDE 33: Summary Variables in Observational Resesarch: Propensity Scores and Disease Risk Scores (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/observational-research-scores_research.pdf
     May 01, 2012 - If a patient has high cholesterol and is on other medications, then the potential for drug-drug interactions … For example, perhaps an adverse effect of a drug is only apparent when the drug is prescribed to people … Pharmacoepidemiol Drug Saf 2005;14:S22- 3. 16. … Pharmacoepidemiol Drug Safety 2005;14(7):465-76. … Pharmacoepidemiol Drug Saf 2005;14:S21.

239. AHRQ Evidence-based Practice Center Program Research Gaps Summary: Primary Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/research-gap-primary-care-summary-table.pdf
     March 01, 2022 - Therapy and Drug Holidays for Osteoporosis Fracture Prevention: A Systematic Review ................ … Food and Drug Administration warrants further research and ongoing post marketing surveillance. …  Motivational interviewing decreases combined alcohol and other drug use. … treatment and of osteoporosis drug treatment discontinuation and holidays. … Key Messages • Evidence on the effects of long-term osteoporosis drug treatment and drug continuation

240. Depression SSRI Surveillance Assessment_CER 62_Low-1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-treatment-ssri_surveillance.pdf
     January 01, 2013 - Food and Drug Administration (FDA), Health Canada, and UK Medicines and Healthcare products Regulatory … would produce prima facie evidence that a conclusion was out of date, such as the withdrawal of a drug … from the market, a 3 black box warning) or the availability of a new drug within class (the … Overall, there is limited supportive evidence for any single augmenting drug or for switching to a … or treat*)).tw. 39 ((treat* or therapy or drug) adj4 (resist* or fail*)).tw. 40 27 or 28 or 29