-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-drugs-utilization_research.pdf
January 01, 2011 - Not all biologics are Food and Drug Administration-labeled
(i.e., indicated) for the conditions in which … developed guide-
lines for medically accepted off-label use of anticancer biologics,
using published drug … integrate information
from five various compendia providers (American Hospital
Formulary Service Drug … Prescription Drug Event
(PDE) data were used to identify
Medicare Part D eligibility and biolog-
ics … , Active Ingredient, Age, Gender, and
Race, 2006-2009
Proportion of FFS Drug Users With a
200.x-208
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/unpublished-drug-trials-white-paper.pdf
December 01, 2024 - Food and Drug Administration (FDA) drug approval
packages (i.e., FDA reviews) into three systematic … Food and Drug Administration (FDA). … Food and Drug Administration.
7
4. … Drug Class Reviews. … Food and
Drug Administration; 2001.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-drugs-utilization-cost_research.pdf
January 01, 2011 - Medicare fee-for-service (FFS) payments
(excluding Part C advantage plans and Part D prescription
drug … costs to prescription drug plans. … Peginterferon
alfa-2a ranked highest among anticancer biologics, at #9.7
Although the Food and Drug … Drug
Event (PDE) file, a dataset containing summary records of
drug dispensing from prescription drug … Biotech drug spending increases 21 percent even as growth
in rx expenditure slows.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/stent-clopidogrel-practice_research.pdf
March 01, 2009 - Clopidogrel after Drug-Eluting Stent Implantation: Is current practice sufficient
The DEcIDE ( … Clopidogrel use and long-term clinical outcomes after drug-eluting stent implantation. … Clopidogrel after drug-eluting stent implantation: is current
practice sufficient? … Of the 4666 patients remaining, 3165
received a bare metal and 1501 a drug-eluting stent. … :
an observational study of drug-eluting
versus bare-metal stents.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/off-label-use-research-priorities_research.pdf
May 01, 2009 - and drug interactions. … Food and Drug Administration, Center for
Drug Evaluation and Review. … /Drug Safety
Diane Kennedy, RPh, MPH Food and Drug Administration Regulator/Drug Analysis
Laurie … has serious side effects.**
2) The drug has frequent side effects.
3) The drug has serious drug-drug … interactions.**
4) The drug has frequent drug-drug interactions.*
5) The drug is approved in other
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f1-surv-report-1-nonopioid-pharmacol-chronic-pain.xlsx
May 29, 2025 - Pain severity for neuropathic pain
Author, Year Quality Pain Population Drug Class 1 Drug Class 2 Drug … Sleep outcomes for neuropathic pain
Author, Year Quality Pain Population Drug Class 1 Drug Class 2 Drug … Pain severity for fibroyalgia
Author, Year Quality Pain Population Drug Class 1 Drug Class 2 Drug 1 … Anxiety outcomes for fibromyalgia
Author, Year Quality Pain Population Drug Class 1 Drug Class 2 Drug … Sleep outcomes for fibromyalgia
Author, Year Quality Pain Population Drug Class 1 Drug Class 2 Drug
-
effectivehealthcare.ahrq.gov/sites/default/files/data-points-9_maps.pdf
May 29, 2025 - 2009
Annual Utilization of Sulfonylureas Among Diabetic Beneficiaries With At Least One Antidiabetic Drug … Annual Utilization of Sulfonylureas Among Diabetic Beneficiaries With At Least One Antidiabetic Drug … Annual Utilization of Sulfonylureas Among Diabetic Beneficiaries With At Least One Antidiabetic Drug … Annual Utilization of Sulfonylureas Among Diabetic Beneficiaries With At Least One Antidiabetic Drug … Annual Utilization of Insulin Among Diabetic Beneficiaries With At Least One Antidiabetic Drug
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f1-surv-report-2-nonopioid-pharmacol-chronic-pain.xlsx
May 29, 2025 - Pain severity for neuropathic pain
Author, Year Quality Pain Population Drug Class 1 Drug Class 2 Drug … Sleep outcomes for neuropathic pain
Author, Year Quality Pain Population Drug Class 1 Drug Class 2 Drug … Pain severity for fibromyalgia
Author, Year Quality Pain Population Drug Class 1 Drug Class 2 Drug 1 … Anxiety outcomes for fibromyalgia
Author, Year Quality Pain Population Drug Class 1 Drug Class 2 Drug … Sleep outcomes for fibromyalgia
Author, Year Quality Pain Population Drug Class 1 Drug Class 2 Drug
-
effectivehealthcare.ahrq.gov/sites/default/files/s96.pdf
October 01, 2007 - Key Words: adverse drug reaction reporting systems,
surveillance, drug safety
(Med Care 2007;45: S96 … –S102)
An adverse drug event (ADE) occurs when a drug intended
for therapeutic use has an unintended … or a drug-specific
effect. … How the US Food and Drug Administration defines and
detects adverse drug events. … Incidence of adverse drug events
and potential adverse drug events. Implications for prevention.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/medication-therapy-management-1_research.pdf
July 01, 2012 - events) and real (adverse drug events being a subset of the drug
related problems) drug related problems … events, and assess medication
appropriateness, potential drug-drug and drug-food interactions, dose … drug related problems. … The patient is having an adverse
drug event (ADE) as a result of the drug.
a. … Does the patient have an allergy to the drug or
similar drug? (7.1)
b.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f1-surv-report-3-nonopioid-pharmacol-chronic-pain.xlsx
May 29, 2025 - Pain severity for neuropathic pain
Author, Year Quality Pain Population Drug Class 1 Drug Class 2 Drug … Sleep outcomes for neuropathic pain
Author, Year Quality Pain Population Drug Class 1 Drug Class 2 Drug … Pain severity for fibromyalgia
Author, Year Quality Pain Population Drug Class 1 Drug Class 2 Drug 1 … Anxiety outcomes for fibromyalgia
Author, Year Quality Pain Population Drug Class 1 Drug Class 2 Drug … Sleep outcomes for fibromyalgia
Author, Year Quality Pain Population Drug Class 1 Drug Class 2 Drug
-
effectivehealthcare.ahrq.gov/products/rheumatoid-arthritis-medicine-update/final-report-update-2018
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f2-surv-report-1-nonopioid-pharmacol-chronic-pain.xlsx
May 29, 2025 - Harms of tricyclic antidepressants versus placebo
Author, Year Quality Pain Population Drug Class Drug … Harms of pregabalin versus placebo
Author, Year Quality Pain Population Drug Class Drug Assessment Time … Harms of pregabalin versus amitriptyline
Author, Year Quality Pain Population Drug Class Drug Assessment … Harms of pregabalin CR versus IR
Author, Year Quality Pain Population Drug Class Drug Assessment Time … Harms of cannabis versus placebo
Author, Year Quality Pain Population Drug Assessment Time (Wk) Time
-
effectivehealthcare.ahrq.gov/sites/default/files/diverticulitis-nomination-extra.pdf
May 29, 2025 - interventional
radiology)
• Surgical resection
with primary
anastomosis
• Hartmann’s
procedure
Drug … (ex. 5-amino
salicylates, etc.) and non-
drug (ex. dietary)
interventions
KQ1: Antibiotics KQ1 … Hartmann's procedure
No intervention, other
drug, other non-drug,
drug vs. non-drug,
combinations
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f2-surv-report-3-nonopioid-pharmacol-chronic-pain.xlsx
May 29, 2025 - Harms of tricyclic antidepressants versus placebo
Author, Year Quality Pain Population Drug Class Drug … Harms of pregabalin versus placebo
Author, Year Quality Pain Population Drug Class Drug Assessment Time … Harms of pregabalin versus amitriptyline
Author, Year Quality Pain Population Drug Class Drug Assessment … Harms of pregabalin CR versus IR
Author, Year Quality Pain Population Drug Class Drug Assessment Time … Harms of naproxen versus placebo
Author, Year Quality Pain Population Drug Class Drug Assessment Time
-
effectivehealthcare.ahrq.gov/products/high-risk-drugs/protocol
-
effectivehealthcare.ahrq.gov/sites/default/files/s9.pdf
October 01, 2007 - drug subsidy. … Coverage for the prescription drug benefit is provided
under various types of prescription drug plans … ) prescription drug
plans (MA-PDPs), which offer prescription drug coverage
that is integrated with the … Medicare Part D Prescription Drug Event (PDE) Data. … Total Medicare Beneficiaries With Drug Coverage
as of June 11, 2006
Description
June
(Millions)
Drug
-
effectivehealthcare.ahrq.gov/sites/default/files/s13.pdf
October 01, 2007 - , or the drug indication itself. … to prove drug efficacy (ie, the possibility of a
beneficial effect in an ideal setting), but not drug … effec-
tiveness (ie, whether the drug works in reality).3 Further,
information on comparative drug effectiveness … type, how long the drug has been
taken, how recently the drug was taken, and demographics of
the patient … US Food and Drug Administration.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/medicine-safety-call-center_research.pdf
September 01, 2007 - for monitoring and detecting adverse drug events. … Detecting adverse drug events is a difficult problem. … interactions and monitoring drug safety. … (Center for Drug Evaluation and
Research [CDER], 2005). … Reporting mechanisms need to be
customized for each drug and drug combinations to collect relevant
-
effectivehealthcare.ahrq.gov/sites/default/files/it-architecture-for-post-marketing-surveillance-arizona-cert.pdf
September 01, 2007 - for monitoring and detecting adverse drug events. … Detecting adverse drug events is a difficult problem. … interactions and monitoring drug safety. … (Center for Drug Evaluation and
Research [CDER], 2005). … Reporting mechanisms need to be
customized for each drug and drug combinations to collect relevant