-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/juvenile-arthritis-dmards_research-protocol.pdf
March 09, 2010 - Furthermore,
there are a large number of DMARDs that cannot simply be grouped by drug class. … Failure with
a drug in one particular class does not necessarily predict failure with another drug in … and the drug
is relatively inexpensive. … Generic Name US Trade
Name Drug Type
Approved by the
US Food and
Drug
Administration-
for JIA … Generic Name US Trade Name Mechanism of
Action
Approved by
the US Food
and Drug
Administration
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/opioids-oa-protocol.pdf
June 29, 2019 - metabolism, polypharmacy (resulting in
drug-drug interactions), compromised respiration, hypogonadism … Adults: 2015 National Survey on Drug Use and Health. … High Prevalence of Drug-Drug
Interactions in Primary Health Care is Caused by Prescriptions from other … Reducing the risk of adverse drug
events in older adults. … Am J Drug Alcohol Abuse.
2015;41(6):508-518.
39.
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effectivehealthcare.ahrq.gov/sites/default/files/14_substanceabuse_potential_high_impact_june_2012.pdf
January 01, 2012 - Food and Drug Administration (FDA) in October
2011 about preparing its new drug application, and the … company announced that
FDA supported submission of a new drug application via the 505(b)(2) pathway … Public Health Service, guidelines for smoking cessation recommend drug
therapy (e.g., bupropion and … National Institute on Drug Abuse (NIDA).
Prescription drugs: abuse and addiction. [internet]. … Food and Drug Administration. [internet].
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-215-depression-older-adults-comments.pdf
March 28, 2019 - The a priori determined unit of analysis
was drug class. … In some instances, where only a single
drug was represented in a class, we
provide that drug name so … , not just by drug class vs. … When data for a single
drug was available, the drug level
comparison is presented (ex. duloxetine … In the “Discussion” chapter under
“applicability” we have added “Resulting
drug-drug interactions and
-
effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1506.pdf
June 01, 2015 - Personalized drug therapy has traditionally lagged behind behavioral
therapy in this regard because … Biopharm Drug Dispos. 2003
Jan;24(1):37-43. Also available:
http://dx.doi.org/10.1002/bdd.336. … Drug Enforcement Administration. … Research suggests new drug targets for
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(DC): Drug Enforcement Administration, U.S.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotic-medicine-cardiovascular-elderly_research.pdf
February 01, 2009 - Reasons for using both drug groups (e.g., dementia, delirium) may themselves be risk
factors for these … just new users to guard against selection bias among prevalent users from
early symptom emergence, drug … Food and Drug Administration. … Available at:
www.fda.gov/cder/drug/advisory/antipsycho
tics.htm. Accessed April 15, 2005.
2. … http://www.fda.gov/cder/drug/advisory/antipsychotics.htm
http://www.fda.gov/cder/drug/advisory/antipsychotics.htm
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/allergy-seasonal_executive.pdf
July 01, 2013 - Food and Drug Administration (FDA) for the treatment
of SAR. … within a drug class. … Because
physiologic changes of pregnancy alter drug disposition,
Table D. … Alterations in drug disposition during
pregnancy: implications for drug therapy. … Expert Opin Drug Metab
Toxicol. 2007 Aug;3(4):557-71. PMID: 17696806.
55.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/calcineurin-inhibitor_research-protocol.pdf
October 08, 2014 - These
patients present special challenges as there are drug-drug interactions between CNIs and protease … Studies that only evaluate drug pharmacokinetics will also
be excluded. … Ther Drug
Monit. 2009;31:139-52.
9. Bouamar R, Shuker N, Hesselink DA, et al. … Drug-drug interactions between
antiretroviral and immunosuppressive agents in
HIV-infected patients … monitoring
terms
'drug monitoring'/exp OR 'drug monitoring' OR ((drug OR therapy OR
therapeutic)
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-risk-drugs-protocol.pdf
July 27, 2023 - Protocol
Project Title: Making Healthcare Safer IV:
Protocols for High-Risk Drugs: Reducing Adverse Drug … The “Protocols for High-Risk Drugs:
Reducing Adverse Drug Events Related to Anticoagulants” as a patient … Event
Prevention (ADE Action Plan) identified anticoagulants as a leading cause of adverse
drug … cause-specific mortality, bleeding,
hemorrhage, stroke, quality of life, adverse
events associated with drug-drug … US
Emergency Department Visits for Outpatient Adverse Drug Events, 2013-2014.
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effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1506.pdf
June 01, 2015 - FDA approves Qsymia, a weight-loss
drug. [internet]. … Food and Drug Administration (FDA); 2014 Dec
23 [accessed 2015 Feb 03]. [5 p]. … Ther Adv Drug Saf.
2013;4(4):171-81. … Novo Nordisk to promote drug to treat obesity in
United States. [internet]. … Medica 2015 comprehensive preferred drug list
(PDL).
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effectivehealthcare.ahrq.gov/sites/default/files/dementia_hi_impact.pdf
January 01, 2012 - similar
drugs in the same class are read separately), and then topics in the same class of a device, drug … Phase III clinical trials for florbetapir have been completed and a
new drug application was submitted … Food and Drug Administration (FDA) in
January 2011 that FDA considered and led to ongoing controversy … Committee briefing document:
Peripheral and central nervous system drugs
advisory committee: New drug … Food and Drug
Administration (FDA); 2010 Dec 20. 86 p.
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effectivehealthcare.ahrq.gov/sites/default/files/07_diabetes_potential_high_impact_2012-12-10.pdf
January 01, 2012 - The drug/device has been approved in Europe. … Food and Drug Administration (FDA). … Food and Drug Administration
(FDA); 2012 Nov 9. 63 p. … Drug list search results:
bydureon. [internet]. … FDA approves eye drug for diabetics.
[internet].
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_disposition-comments.pdf
March 01, 2012 - All that can be said is
that a particular drug or class of drug is effective in some patients
and not … If the drug was
working in the first place, why would the patient be put back on
the old drug rather … class of drug on the epilepsy
syndrome. … Therefore, when exploring this
topic, concentration, drug-drug interactions, and the fact that
phenytoin … the first drug prescribed for the patient.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-bone-fracture_executive.pdf
March 01, 2012 - Nevertheless, the drug is still
widely prescribed. … , and single drug versus single drug
comparisons for drugs within the same class and across
classes … versus placebo,
and comparisons of drug versus drug, for drugs within
the same class and across classes … The Food and Drug Administration’s Osteoporosis
Guidance Document: past, present, and future. … Rockville, MD: Food and Drug Administration, Division of
Metabolic and Endocrine Drug Products; 1994
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonopioid-pharm-chronic-pain-protocol.pdf
February 01, 2019 - Specific adverse events for each drug class, such as
gastrointestinal events, cardiovascular events, … sedation for gabapentin/pregabalin
• Intermediate outcomes (e.g.,
pharmacokinetics/pharmacodynamics,
drug-drug … Pharmacoepidemiol Drug Saf. 2009;18(12):1166-75. doi: 10.1002/pds.1833. PMID: 19718704
7. … Pharmacoepidemiology and drug safety. 2009;18(12):1166-75.
15. Higgins J, Green S. … Methods for the Drug Effectiveness Review Project.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/assessing-applicability-quiz.ppt
May 29, 2025 - The impact of a drug on bone mineral density in young, male, well-trained astronauts in outer space may … The impact of a drug on bone mineral density in young, male, well-trained astronauts in outer space may … The impact of a drug on bone mineral density in young, male, well-trained astronauts in outer space may … The impact of a drug on bone mineral density in young, male, well-trained astronauts in outer space may
-
effectivehealthcare.ahrq.gov/sites/default/files/assessing-applicability-quiz.ppt
May 29, 2025 - The impact of a drug on bone mineral density in young, male, well-trained astronauts in outer space may … The impact of a drug on bone mineral density in young, male, well-trained astronauts in outer space may … The impact of a drug on bone mineral density in young, male, well-trained astronauts in outer space may … The impact of a drug on bone mineral density in young, male, well-trained astronauts in outer space may
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effectivehealthcare.ahrq.gov/sites/default/files/diabetes-update-2015_executive.pdf
January 01, 2015 - Food and Drug Administration. … Food and Drug Administration. … Food and Drug Administration. … Food and Drug Administration. … Food and Drug Administration.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/schizophrenia-adult_research-protocol.pdf
September 23, 2016 - Drug Class Review of Atypical Antipsychotic Drugs;
Update 3. … Portland, OR: Oregon Health & Science University Drug Effectiveness Review Project;
2010.
17. … Antipsychotic drug use and mortality in older adults
with dementia. … Drug Class Review: Second Generation Antipsychotic
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34.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/atypical-antipsychotics-off-label-update_disposition-comments.pdf
September 01, 2011 - That raises the question: Why focus on
off-label use since expanding FDA approval for an approved drug … We included studies
comparing atypicals to other
drug classes throughout the
report. … Similarly, our summary table of
benefits (Table 1) lists each
drug seperately for each
indication. … Pharmacoepidemiology and drug safety (2011) DOI: 10.1002/pds.2082 The study
results
indicated 75% … In addition, it shows a trend towards worsening
psychosis with this drug.