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Total Results: 2,080 records

Showing results for "drug".

181. PULMONARY with "Discussions" in Exec Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1412.pdf
     October 01, 2015 - the drug cost. … In November 2014, the company submitted a new drug application to the U.S. … Early success for Kalydeco is just the beginning for Vertex's CF drug. … Food and Drug Administration (FDA). … Vertex's two-drug cystic fibrosis treatment shows promise. [internet].

182. Management of Suspected Opioid Overdose With Naloxone by Emergency Medical Services Personnel - Executive Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-193-naloxone-executive-summary.pdf
     November 01, 2017 - Food and Drug Administration. 2016 Meeting Materials, Anesthetic and Analgesic Drug Products Advisory … Joint meeting of the anesthetic and analgesic drug products advisory committee and the drug safety and … Joint meeting of the anesthetic and analgesic drug products and the drug safety and risk management … Food and Drug Administration. … Joint meeting of anesthetic and analgesic drug products advisory committee and drug safety and risk

183. Epilepsy-Medicine Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_surveillance.pdf
     August 01, 2012 - evaluations and one search capturing older versus newer antiepileptic drug evaluations. … Comparative efficacy of combination drug therapy in refractory epilepsy. … Antiepileptic drug combinations--have newer agents altered clinical outcomes? … Pharmacotherapy:The Journal of Human Pharmacology & Drug Therapy. 2012 Apr;32(4):314-22. … drug therapy.fs. 6. randomly.ab. 7. trial.ab. 8. groups.ab. 9.

184. Epilepsy-Medicine Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_surveillance.pdf
     August 01, 2012 - evaluations and one search capturing older versus newer antiepileptic drug evaluations. … Comparative efficacy of combination drug therapy in refractory epilepsy. … Antiepileptic drug combinations--have newer agents altered clinical outcomes? … Pharmacotherapy:The Journal of Human Pharmacology & Drug Therapy. 2012 Apr;32(4):314-22. … drug therapy.fs. 6. randomly.ab. 7. trial.ab. 8. groups.ab. 9.

185. DEMENTIA INCLUDING ALZHEIMER'S #04 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1506.pdf
     June 01, 2015 - similar drugs in the same class are read separately), and then topics in the same class of a device, drug … preliminary phase III data for drugs (or preliminary late-phase clinical trial data for off-label drug … Food and Drug Administration has not approved an AD-treating drug since galantamine in 2004. … We continue to monitor early developments of new drug candidates and diagnostics in this priority area … This drug, in various formulations, is approved and widely used to manage diabetes indications; no major

186. Rheumatoid-Arthritis-Medicine Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-medicine_executive.pdf
     April 01, 2012 - 1 Comparative Effectiveness Review Number 55 Drug Therapy for Rheumatoid Arthritis in Adults: An … The Key Questions (KQs) are as follows: KQ1: For patients with RA, do drug therapies differ in their … Hand searches were conducted on the Center for Drug Evaluation and Research (CDER) database of the … Our major findings are presented in this section by type of drug comparison for benefits and harms ( … Drug Therapy for Rheumatoid Arthritis in Adults: An Update.

187. #14 SUBSTANCE ABUSE (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1306.pdf
     June 01, 2013 - Opioid abuse is one of the most common forms of prescription drug abuse. … The company submitted a new drug application to the U.S. … Food and Drug Administration (FDA) in October 2012. … recommend approval; however, on April 30, 2013, the company announced that FDA did not approve the drug … If new trials are needed, resubmission of a new drug application would be delayed for a considerable

188. Disease-Modifying Antirheumatic Drugs (DMARDs) in Children With Juvenile Idiopathic Arthritis (JIA) | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/juvenile-arthritis-dmards/research
     September 26, 2011 - There are few direct comparisons of DMARDs, and insufficient evidence to determine if any specific drug … or drug class has greater beneficial effects.

189. Ced-Topic-Refinement (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ced-topic-refinement.pdf
     November 01, 2022 - Framework for FDA's Real-World Evidence Program US Food & Drug Administration. … and Biological Products US Food & Drug Administration. … Guidance for Industry US Food & Drug Administration. … and Biological Products US Food & Drug Administration. … Data Standards for Drug and Biological Product Submissions Containing Real-World Data US Food & Drug

190. Pulmonary Arterial Hypertension: Screening, Management, and Treatment | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/hypertension-pulmonary-arterial/research
     April 25, 2013 - Thirty-seven studies involving 4,192 patients assessed the effectiveness of drug treatments for PAH in … All drug classes demonstrated increases in 6WMD when compared with placebo, but comparisons between agents … Each drug class showed a favorable impact on at least two of the three hemodynamic outcomes: cardiac … Comparisons of different drug combinations were inconclusive regarding a mortality reduction but suggested … an improvement in 6MWD when a second drug was added to existing monotherapy.

191. Comparative Effectiveness and Safety of New Therapies (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-glucose-control_research.pdf
     July 01, 2010 - We evaluated whether early use of this drug was consistent with the FDA-approved indications for use … The dataset included patients with a diagnosis of DM, or a claim for a drug used to treat DM, between … (San Diego, CA), was approved by the FDA on April 28, 2005.2 Exenatide is a first-in-class drug that … If the patient had sufficient drug-on-hand for 2 Effective Health Care Program Research Report … Discussion The early users of this new drug (in the first six months since approval) were largely

192. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0128_07-01-2009.pdf
     January 01, 2009 - Effective Health Care Topic Number: 0167 Document Completion Date: 1-11-10 1 Results of Topic Selection Process & Next Steps  Generic versus brand name antiepileptic drugs for the treatment of epilepsy will be addressed as part of a larger in-process systematic review on treatment of epilepsy t…

193. Research on Optimal Second-Line Therapy for Hypertension | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/hypertension-therapy/abstract
     January 01, 2005 - Besides its high prevalence, hypertension generally requires drug treatment – and control to desired … levels often requires more than one drug – so that the population impact of prevalence, compounded by … Specific aims are: to describe patterns of antihypertensive drug use; to compare the changes in intermediate

194. Making Healthcare Safer IV: Summary of Findings, 2023-2024 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-1-year-final-report-updated-title_0.pdf
     May 01, 2024 - Computerized Clinical Decision Support To Prevent Medication Errors and Adverse Drug Events ........ … Reducing Adverse Drug Events Related to Anticoagulant Use in Adults 9a. … involving CDSS to reduce medication errors and adverse drug events. … Computerized Clinical Decision Support To Prevent Medication Errors and Adverse Drug Events 1a. … Reducing Adverse Drug Events Related to Anticoagulant Use in Adults 9a.

195. Acute Treatment for Episodic Migraine: Surveillance Report 2 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/episodic-migraine-surveillance-report-2.pdf
     June 01, 2022 - Reviews, PsycINFO®, and Scopus from September 2, 2021 to December 30, 2021.We also searched Food and Drug … Placebo From the previous report, NSAIDs as a drug class, compared with placebo, resolved pain at … No change in SOE supporting the effect of NSAIDs as a drug class vs. … analyses Abbreviations: KQ = Key Question; mg = milligram; NSAID = nonsteroidal anti-inflammatory drug … Therapy] 24 exp Vomiting/dt [Drug Therapy] 25 (((drug* or agent* or medication*) adj3 (nausea or

196. PEPTIC ULCER #11 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1506.pdf
     June 01, 2015 - Drug Enforcement Administration. … The drug was subsequently studied for its potential to reduce IBS symptoms, such as diarrhea. … Food and Drug Administration (FDA) for treating diarrhea-predominant IBS. … Some experts believe that concerns about overuse of antibiotics might limit the use of the drug. … Food and Drug Administration (FDA); 2015 May 27 [accessed 2015 Jun 03]. [5 p].

197. Survey of Medicare Part D Plans’ Medication Therapy Management Programs | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/medication-therapy-management-1/research-2007
     March 16, 2007 - Abstract Purpose The Medicare Prescription Drug, Improvement and Modernization Act of 2003 included … The broad definition of MTM program in this Act allowed Prescription Drug Plans (PDPs) and Medicare Advantage … Drug Plans (MA-PDs) to develop a wide variety of MTM services.

198. Methods-Guidance-Reporting-Bias Methods (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-reporting-bias_methods.pdf
     November 01, 2013 - Food and Drug Administration. … Drug Approval Process Manufacturers are required to submit a New Drug Application to the FDA for all … The Drugs@FDA site may be searched by the generic or trade drug name (not drug class) for Statistical … Reporting bias in drug trials submitted to the Food and Drug Administration: review of publication … Drug Effectiveness Review Project.

199. Rheumatoid-Arthritis-Medicine Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-medicine_surveillance.pdf
     March 01, 2013 - CER #55: Drug Therapy for Rheumatoid Arthritis in Adults: An Update Original release date: April … Introduction Comparative Effectiveness Review (CER) #55, Drug Therapy for Rheumatoid Arthritis in … This drug is not a biologic. … Drug Therapy for Rheumatoid Arthritis in Adults: An Update. … Risk did not differ significantly by specific drug.

200. Rheumatoid-Arthritis-Medicine Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_surveillance.pdf
     March 01, 2013 - CER #55: Drug Therapy for Rheumatoid Arthritis in Adults: An Update Original release date: April … Introduction Comparative Effectiveness Review (CER) #55, Drug Therapy for Rheumatoid Arthritis in … This drug is not a biologic. … Drug Therapy for Rheumatoid Arthritis in Adults: An Update. … Risk did not differ significantly by specific drug.