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Showing results for "drug".

  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/juvenile-arthritis-dmards_research-protocol.pdf
    March 09, 2010 - Furthermore, there are a large number of DMARDs that cannot simply be grouped by drug class. … Failure with a drug in one particular class does not necessarily predict failure with another drug in … and the drug is relatively inexpensive. … Generic Name US Trade Name Drug Type Approved by the US Food and Drug Administration- for JIA … Generic Name US Trade Name Mechanism of Action Approved by the US Food and Drug Administration
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/opioids-oa-protocol.pdf
    June 29, 2019 - metabolism, polypharmacy (resulting in drug-drug interactions), compromised respiration, hypogonadism … Adults: 2015 National Survey on Drug Use and Health. … High Prevalence of Drug-Drug Interactions in Primary Health Care is Caused by Prescriptions from other … Reducing the risk of adverse drug events in older adults. … Am J Drug Alcohol Abuse. 2015;41(6):508-518. 39.
  3. #14 SUBSTANCE ABUSE (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/14_substanceabuse_potential_high_impact_june_2012.pdf
    January 01, 2012 - Food and Drug Administration (FDA) in October 2011 about preparing its new drug application, and the … company announced that FDA supported submission of a new drug application via the 505(b)(2) pathway … Public Health Service, guidelines for smoking cessation recommend drug therapy (e.g., bupropion and … National Institute on Drug Abuse (NIDA). Prescription drugs: abuse and addiction. [internet]. … Food and Drug Administration. [internet].
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-215-depression-older-adults-comments.pdf
    March 28, 2019 - The a priori determined unit of analysis was drug class. … In some instances, where only a single drug was represented in a class, we provide that drug name so … , not just by drug class vs. … When data for a single drug was available, the drug level comparison is presented (ex. duloxetine … In the “Discussion” chapter under “applicability” we have added “Resulting drug-drug interactions and
  5. #05 DEPRESSION (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1506.pdf
    June 01, 2015 - Personalized drug therapy has traditionally lagged behind behavioral therapy in this regard because … Biopharm Drug Dispos. 2003 Jan;24(1):37-43. Also available: http://dx.doi.org/10.1002/bdd.336. … Drug Enforcement Administration. … Research suggests new drug targets for depression. … Washington (DC): Drug Enforcement Administration, U.S.
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotic-medicine-cardiovascular-elderly_research.pdf
    February 01, 2009 - Reasons for using both drug groups (e.g., dementia, delirium) may themselves be risk factors for these … just new users to guard against selection bias among prevalent users from early symptom emergence, drug … Food and Drug Administration. … Available at: www.fda.gov/cder/drug/advisory/antipsycho tics.htm. Accessed April 15, 2005. 2. … http://www.fda.gov/cder/drug/advisory/antipsychotics.htm http://www.fda.gov/cder/drug/advisory/antipsychotics.htm
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/allergy-seasonal_executive.pdf
    July 01, 2013 - Food and Drug Administration (FDA) for the treatment of SAR. … within a drug class. … Because physiologic changes of pregnancy alter drug disposition, Table D. … Alterations in drug disposition during pregnancy: implications for drug therapy. … Expert Opin Drug Metab Toxicol. 2007 Aug;3(4):557-71. PMID: 17696806. 55.
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/calcineurin-inhibitor_research-protocol.pdf
    October 08, 2014 - These patients present special challenges as there are drug-drug interactions between CNIs and protease … Studies that only evaluate drug pharmacokinetics will also be excluded. … Ther Drug Monit. 2009;31:139-52. 9. Bouamar R, Shuker N, Hesselink DA, et al. … Drug-drug interactions between antiretroviral and immunosuppressive agents in HIV-infected patients … monitoring terms 'drug monitoring'/exp OR 'drug monitoring' OR ((drug OR therapy OR therapeutic)
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-risk-drugs-protocol.pdf
    July 27, 2023 - Protocol Project Title: Making Healthcare Safer IV: Protocols for High-Risk Drugs: Reducing Adverse Drug … The “Protocols for High-Risk Drugs: Reducing Adverse Drug Events Related to Anticoagulants” as a patient … Event Prevention (ADE Action Plan) identified anticoagulants as a leading cause of adverse drug … cause-specific mortality, bleeding, hemorrhage, stroke, quality of life, adverse events associated with drug-drug … US Emergency Department Visits for Outpatient Adverse Drug Events, 2013-2014.
  10. Obesity (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1506.pdf
    June 01, 2015 - FDA approves Qsymia, a weight-loss drug. [internet]. … Food and Drug Administration (FDA); 2014 Dec 23 [accessed 2015 Feb 03]. [5 p]. … Ther Adv Drug Saf. 2013;4(4):171-81. … Novo Nordisk to promote drug to treat obesity in United States. [internet]. … Medica 2015 comprehensive preferred drug list (PDL).
  11. effectivehealthcare.ahrq.gov/sites/default/files/dementia_hi_impact.pdf
    January 01, 2012 - similar drugs in the same class are read separately), and then topics in the same class of a device, drug … Phase III clinical trials for florbetapir have been completed and a new drug application was submitted … Food and Drug Administration (FDA) in January 2011 that FDA considered and led to ongoing controversy … Committee briefing document: Peripheral and central nervous system drugs advisory committee: New drug … Food and Drug Administration (FDA); 2010 Dec 20. 86 p.
  12. Diabetes Mellitus (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/07_diabetes_potential_high_impact_2012-12-10.pdf
    January 01, 2012 - The drug/device has been approved in Europe. … Food and Drug Administration (FDA). … Food and Drug Administration (FDA); 2012 Nov 9. 63 p. … Drug list search results: bydureon. [internet]. … FDA approves eye drug for diabetics. [internet].
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_disposition-comments.pdf
    March 01, 2012 - All that can be said is that a particular drug or class of drug is effective in some patients and not … If the drug was working in the first place, why would the patient be put back on the old drug rather … class of drug on the epilepsy syndrome. … Therefore, when exploring this topic, concentration, drug-drug interactions, and the fact that phenytoin … the first drug prescribed for the patient.
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-bone-fracture_executive.pdf
    March 01, 2012 - Nevertheless, the drug is still widely prescribed. … , and single drug versus single drug comparisons for drugs within the same class and across classes … versus placebo, and comparisons of drug versus drug, for drugs within the same class and across classes … The Food and Drug Administration’s Osteoporosis Guidance Document: past, present, and future. … Rockville, MD: Food and Drug Administration, Division of Metabolic and Endocrine Drug Products; 1994
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonopioid-pharm-chronic-pain-protocol.pdf
    February 01, 2019 - Specific adverse events for each drug class, such as gastrointestinal events, cardiovascular events, … sedation for gabapentin/pregabalin • Intermediate outcomes (e.g., pharmacokinetics/pharmacodynamics, drug-drug … Pharmacoepidemiol Drug Saf. 2009;18(12):1166-75. doi: 10.1002/pds.1833. PMID: 19718704 7. … Pharmacoepidemiology and drug safety. 2009;18(12):1166-75. 15. Higgins J, Green S. … Methods for the Drug Effectiveness Review Project.
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/assessing-applicability-quiz.ppt
    May 29, 2025 - The impact of a drug on bone mineral density in young, male, well-trained astronauts in outer space may … The impact of a drug on bone mineral density in young, male, well-trained astronauts in outer space may … The impact of a drug on bone mineral density in young, male, well-trained astronauts in outer space may … The impact of a drug on bone mineral density in young, male, well-trained astronauts in outer space may
  17. effectivehealthcare.ahrq.gov/sites/default/files/assessing-applicability-quiz.ppt
    May 29, 2025 - The impact of a drug on bone mineral density in young, male, well-trained astronauts in outer space may … The impact of a drug on bone mineral density in young, male, well-trained astronauts in outer space may … The impact of a drug on bone mineral density in young, male, well-trained astronauts in outer space may … The impact of a drug on bone mineral density in young, male, well-trained astronauts in outer space may
  18. effectivehealthcare.ahrq.gov/sites/default/files/diabetes-update-2015_executive.pdf
    January 01, 2015 - Food and Drug Administration. … Food and Drug Administration. … Food and Drug Administration. … Food and Drug Administration. … Food and Drug Administration.
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/schizophrenia-adult_research-protocol.pdf
    September 23, 2016 - Drug Class Review of Atypical Antipsychotic Drugs; Update 3. … Portland, OR: Oregon Health & Science University Drug Effectiveness Review Project; 2010. 17. … Antipsychotic drug use and mortality in older adults with dementia. … Drug Class Review: Second Generation Antipsychotic Drugs. Final Report - Update 4. … Methods for the Drug Effectiveness Review Project. BMC Med Res Methodol. 2012;12(1):140. 34.
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/atypical-antipsychotics-off-label-update_disposition-comments.pdf
    September 01, 2011 - That raises the question: Why focus on off-label use since expanding FDA approval for an approved drug … We included studies comparing atypicals to other drug classes throughout the report. … Similarly, our summary table of benefits (Table 1) lists each drug seperately for each indication. … Pharmacoepidemiology and drug safety (2011) DOI: 10.1002/pds.2082 The study results indicated 75% … In addition, it shows a trend towards worsening psychosis with this drug.

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