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  1. #05 DEPRESSION (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/05_depression_potential_high_impact_2012-12-10.pdf
    January 01, 2012 - A drug for psychotic major depression (PMD), for which the U.S. … administration and is known to be a street drug of abuse. … Research suggests new drug targets for depression. … Food and Drug Administration (FDA) [accessed 2012 Mar 15]. [2 p]. … Washington (DC): Drug Enforcement Administration, U.S.
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-pain-opioid-treatment_research-protocol.pdf
    December 19, 2013 - screens, and use of data from prescription drug monitoring 20programs. … The DAWN Report: Highlights of the 2010 Drug Abuse Warning Network (DAWN) Findings on Drug-Related … Food and Drug Administration. … Dose-Response Relationship, Drug/ or Drug Administration Schedule/ or Pain Management/or Clinical Protocols … Patient Compliance/ or Health Services Misuse/ or Substance Abuse Detection/ or Drug Monitoring/ Drug
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-pci-bypass_surveillance.pdf
    May 01, 2013 - would produce prima facie evidence that a conclusion was out of date, such as the withdrawal of a drug … Is the portion of the CER that is probably or certainly out of date an issue of safety (a drug withdrawn … from the market, a black box warning) or the availability of a new drug within class (the latter being … original key questions, the conclusions of the original report, the results of the literature and drug … Comparison of coronary bypass surgery with drug-eluting stenting for the treatment of left main and/
  4. S77 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s77.pdf
    October 01, 2007 - Key Words: drug costs, insurance coverage, Part D, veterans (Med Care 2007;45: S77–S80) Medicare Part … Assuming all generic drug use with 90-day fills, the average reduction in out-of-pocket expenditures … Medicare Data Update: Prescription Drug Coverage Among Beneficiaries. June 2006. … Information for Veterans About the New Medicare Prescription Drug Benefits. August 15, 2006. … drug coverage.
  5. #14 SUBSTANCE ABUSE (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/14_substance_abuse_potential_high_impact_2012-12-11.pdf
    January 01, 2012 - The ES-4 company filed a new drug application with the U.S. … Food and Drug Administration in late October 2012 requesting priority review status. … ) for treating opioid dependence. 15,16 Buprenorphine falls into the Schedule III drug class under … National Institute on Drug Abuse (NIDA). Prescription drugs: abuse and addiction. [internet]. … Food and Drug Administration. [internet].
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-reporting-bias_methods.pdf
    November 01, 2013 - Food and Drug Administration. … Drug Approval Process Manufacturers are required to submit a New Drug Application to the FDA for all … The Drugs@FDA site may be searched by the generic or trade drug name (not drug class) for Statistical … Reporting bias in drug trials submitted to the Food and Drug Administration: review of publication … Drug Effectiveness Review Project.
  7. #05 DEPRESSION (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/depression_hi_impact.pdf
    October 01, 2014 - Food and Drug Administration (FDA) approval of any DBS device for a psychiatric indication. … DBS is indicated to complement conventional drug therapy for MDD or OCD. … dosages or different drug regimens. … The drug different effect size was largest at day 2. … Food and Drug Administration (FDA); 2010 Apr 1 [accessed 2011 May 23]. [19 p].
  8. effectivehealthcare.ahrq.gov/sites/default/files/tnd-0855-170515.pdf
    April 28, 2017 - Yes, this topic represents a health care drug and intervention available in the U.S. 1b. … cell+OR+phone+OR+smart phone+OR+app&recr=Recruiting&type=&rslt=&age_v=&gndr=&cond=diabetes&intr=NOT+drug … +cell+OR+phone+OR+smartphone+OR+app&recr=Recruiting&type=&rslt=&age_v=&gndr=&cond=diabetes&intr=NOT+drug … +cell+OR+phone+OR+smartphone+OR+app&recr=Recruiting&type=&rslt=&age_v=&gndr=&cond=diabetes&intr=NOT+drug … +cell+OR+phone+OR+smartphone+OR+app&recr=Recruiting&type=&rslt=&age_v=&gndr=&cond=diabetes&intr=NOT+drug
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0855-170515.pdf
    April 28, 2017 - Yes, this topic represents a health care drug and intervention available in the U.S. 1b. … cell+OR+phone+OR+smart phone+OR+app&recr=Recruiting&type=&rslt=&age_v=&gndr=&cond=diabetes&intr=NOT+drug … +cell+OR+phone+OR+smartphone+OR+app&recr=Recruiting&type=&rslt=&age_v=&gndr=&cond=diabetes&intr=NOT+drug … +cell+OR+phone+OR+smartphone+OR+app&recr=Recruiting&type=&rslt=&age_v=&gndr=&cond=diabetes&intr=NOT+drug … +cell+OR+phone+OR+smartphone+OR+app&recr=Recruiting&type=&rslt=&age_v=&gndr=&cond=diabetes&intr=NOT+drug
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/emt-naloxon_research-protocol.pdf
    November 29, 2016 - Increases in Drug and Opioid Overdose Deaths--United States, 2000-2014. … Drug Alcohol Depend. 2016 Jun 1;163:16-23. doi: 10.1016/j.drugalcdep.2016.02.042. … Food and Drug Administration; 2014. … Food and Drug Administration; 2015. … Am Health Drug Benefits. 2015 Oct;8(6 Suppl 3):S51-63. PMID: 26629261. 30.
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/horizon-scan_research-2015.pdf
    January 01, 2015 - Food and Drug Administration (FDA) status of products subject to FDA regulation at the time the cost … health benefit a drug provides for a specific indication. … Whether these initiatives will alter drug pricing is unclear at this time, although Dr. … million to $180 million per year in costs of this new drug for the labeled indication. … Food and Drug Administration (FDA).
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine-update_research-protocol.pdf
    May 15, 2017 - Published online: May 15, 2017 Evidence-based Practice Center Systematic Review Protocol Project Title: Drug … However, data on disease-modifying antirheumatic drug (DMARD) use in the first 3 months are limited. … Food and Drug Administration; RA = rheumatoid arthritis; TNF = tumor necrosis factor; ts = targeted … Choosing a RA treatment drug can be difficult with these populations. … Drug Therapy for Rheumatoid Arthritis in Adults: An Update [Internet].
  13. S89 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s89.pdf
    October 01, 2007 - We are currently assessing the use of maxSPRT in drug safety monitoring.18 Drug safety studies entail … Other complications of drug safety studies include use of a drug for multiple indications, off-label … drug use, and potential differences between early and late adopters. … A maximized sequential probability ratio test for vaccine and drug safety surveillance. … Prompt, active, population-based identification of adverse drug reaction signals.
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-pregnancy-postpartum_executive.pdf
    July 01, 2014 - A vs. drug B)? … Using a second drug to augment the effects of the primary drug and comparing this treatment with monotherapy … with a single drug ii. … A vs. drug B)? … Using a second drug to augment the effects of the primary drug and comparing this treatment with monotherapy
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/headaches-pregnancy.pdf
    March 23, 2019 - within class o Same drug(s), different route, treatment duration, initiation time, or other aspect … Food and Drug Administration, other international equivalent agencies, and pharmacopoeia. … For drug levels not available from the databases, we will search for existing systematic reviews. … Curr Drug Metab. 2012 May 1;13(4):474-90. PMID: 22299823. 15. U.S. … Food and Drug Administration.
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-pregnancy-postpartum_research-protocol.pdf
    March 29, 2013 - A vs. drug B)? … Using a second drug to augment the effects of the primary drug and comparing this treatment with monotherapy … with a single drug ii. … A vs. drug B)? … The combination include: (a) Using a second drug to augment the effects of the primary drug and
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/mat-retention-strategies-rapid-review-1.pdf
    August 01, 2020 - drug users: a randomized controlled trial. … Drug and alcohol dependence. 2015;147:122-9. … Drug and opioid-involved overdose deaths—United States, 2013–2017. … Int J Drug Policy. 2018;56:73-80. doi: https://dx.doi.org/10.1016/j.drugpo.2018.03. 012. … drug users: a randomized controlled trial.
  18. #05 DEPRESSION (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/05_depression_potential_high_impact_june_2012.pdf
    January 01, 2012 - A drug for psychotic major depression, for which the U.S. … dosages or different drug regimens. … administration and is known to be a street drug of abuse. … Research suggests new drug targets for depression. … Washington (DC): Drug Enforcement Administration, U.S.
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotic-medicine-mortality-elderly_research.pdf
    March 01, 2009 - and more likely to exclude those who discontinued the drug due to drug intolerance, or treatment failure … http://www.fda.gov/cder/drug/advisory/antipsychotics.htm http://www.fda.gov/cder/drug/advisory/antipsychotics.htm … Drug Saf 2007;30(1):47-57. 35. Wehmeier PM, Heiser P, Remschmidt H. … Adverse Drug React Toxicol Rev 2002;21(4):189-203. 38. Fox CS, Evans JC, Larson MG, et al. … Antipsychotic drug use and mortality in older adults with dementia.
  20. Kravitz_ECCS2012 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/kravitz_eccs2012.pdf
    January 01, 2012 - Food and Drug Administration opened the door in 1997 by reinterpreting own rules. …  (clinical) approaches Slide 18: Policy  Approaches • Improve the quality of the prescription drug … Slide 19: What Is  Being  Done • Drug facts  box o Presents evidence about the benefits and

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