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  1. S58 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s58.pdf
    October 01, 2007 - ORIGINAL ARTICLE Studying Prescription Drug Use and Outcomes With Medicaid Claims Data Strengths, Limitations … Prescription drug claims histories reflect complex and often erratic patterns of use over time. … availability to the patient, not actual drug-taking behavior. … Filled prescriptions, repre- senting a necessary, though not sufficient, condition for drug ingestion … Pharmacoepidemiol Drug Saf. 2003;12:103–111. 16. Crystal S, Sambamoorthi U, Walkup JT, et al.
  2. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-2007_executive.pdf
    January 01, 2007 - pain and inflammation and, ultimately, to slow the progression of joint Comparative Effectiveness of Drug … For patients with rheumatoid arthritis or psoriatic arthritis, do drug therapies differ in their ability … What are the comparative benefits and harms of drug therapies for rheumatoid arthritis and psoriatic … The data are limited by the number of supporting studies for each drug combination. … The data are limited by the number of supporting studies for each drug combination.
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/medication-therapy-management_executive.pdf
    November 01, 2014 - - drug interactions or adverse event � Drug therapy problems that are resolved as defined by primary … studies but typically including the following: needed drug initiated; unnecessary drug discontinued … Gurwitz JH, Rochon P, Food and Drug Administration. … Out-of-Bounds: Rising Prescription Drug Prices for Seniors. … Association of Chain Drug Stores Foundation.
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/indirect-comparisons_research.pdf
    March 01, 2013 - Food and Drug Administration, Center for Drug Evaluation and Research. … Food and Drug Administration, Center for Drug Evaluation and Research. … Food and Drug Administration, Center for Drug Evaluation and Research. … Food and Drug Administration, Center for Drug Evaluation and Research. … Food and Drug Administration, Center for Drug Evaluation and Research.
  5. Obesity (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/10_obesity_potential_high_impact_june_2012.pdf
    January 01, 2012 - Naltrexone/bupropion drug is a combination oral, sustained- release drug intended to fight the body's … A new drug application for treating obesity has not been submitted as of this writing. … This drug combination acts on the central nervous system as an appetite suppressant. … Food and Drug Administration (FDA). … FDA accepts new drug application filing for Qnexa. [internet].
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-seniors-death_research.pdf
    August 01, 2007 - Psychotropic drug use in elderly people with and without dementia. … The quality of antipsychotic drug prescribing in nursing homes. … Food and Drug Administration. … Available at: www.fda.gov/cder/drug/advisory/antipsychotics.ht m. … Paradoxical relations of drug treatment with mortality in older persons.
  7. effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1312.pdf
    December 01, 2013 - -based, online aggregator of prescription drug prices listed prices for the drug at about $27,000 per … Available: http://www.vrtx.com/current-projects/drug- candidates/vx-770.html. … Food and Drug Administration (FDA); 2012 Jan 31 [accessed 2012 Feb 22]. [2 p]. … Drug coverage guidelines. [internet]. … Food and Drug Administration (FDA); [accessed 2012 Jun 28]. [2 p].
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse-drug-therapy_disposition-comments.pdf
    May 13, 2014 - J Stud Alc Drug Dependence. 2012;73 (6):991-997 Thank you for the comment. … longitudinal care coordinated by a primary care clinician with no CCM for people with alcohol or drug … As I said before, if they take the drug at the right dose, it is unlikely that drinking will occur. … J Stud Alc Drug Dependence. 2012;73 (6):991-997. 5. Dunbar JL, Tumcliff RZ, Dong Q, et al. … Only if a trial recruited more patients that responded to drug A than drug B would you get a difference
  9. effectivehealthcare.ahrq.gov/products/diabetes-oral-drugs-safety-knowledge-gaps/research
    January 01, 2005 - Pharmacoepidemiol Drug Saf 2011;20:36-44. Huizinga MM, Roumie CL, Greevy RA, et al. … Pharmacoepidemiol Drug Saf 2010;19:1108-12. Hung AM, Roumie CL, Greevy RA, et al.
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/delirium-research-protocol.pdf
    June 01, 2018 - Currently, there are no medications approved by the Food and Drug Administration for the prevention … antipsychotic drugs cannot be isolated. 7 Comparison • For KQ 1, we will include non-drug … • For KQ 2, we will include non-drug approaches to treating delirium, including placebo, active … Non-drug interventions will be categorized following the scheme developed by Oh and colleagues.19 … Does antipsychotic drug use increase the risk of long term mortality?
  11. effectivehealthcare.ahrq.gov/products/diabetes-glucose-control/research
    August 04, 2010 - Health, Department of Epidemiology Abstract Background: Exenatide was approved by the Food and Drug … We evaluated whether early use of this drug was consistent with the FDA-approved indications for use. … The dataset included patients with a diagnosis of DM, or a claim for a drug used to treat DM, between … (San Diego, CA), was approved by the FDA on April 28, 2005. 2 Exenatide is a first-in-class drug that … , he was considered to have been on this drug for that interval.
  12. effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1512.pdf
    December 01, 2015 - drug- name=orkambi. 14. Walker J. FDA panel backs Vertex cystic-fibrosis drug Orkambi. … drug-name=orkambi http://www.wsj.com/articles/fda-panel-backs-vertex-cystic-fibrosis-drug-orkambi-1431462559 … Policy #DRUG.00080. [internet]. … drug- name=pirfenidone. 71. Medica. … National drug list: drug list - three (3) tier drug plan.
  13. S143 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s143.pdf
    October 01, 2007 - Chief among them is the indication for the drug—a patient must have the condition for which the drug … In a randomized drug trial, the allocation of subjects to treatment and control groups at random leads … Seeger, PharmD, DrPH, Ingenix i3 Drug Safety, 950 Winter Street, Suite 3800, Waltham, MA 02451. … by a text search for the drug name. … Drug treatment of lipid disorders. N Engl J Med. 1999;341: 498–511. 6.
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine_protocol-appendix_20111103.pdf
    November 03, 2011 - Pharmacological classes for migraine prevention Drug, ATC Code* Class of Drug ANTIEPILEPTICS … (continued) Source: www.effectivehealthcare.ahrq.gov Published Online: November 3, 2011 A-2 Drug … (continued) Source: www.effectivehealthcare.ahrq.gov Published Online: November 3, 2011 A-3 Drugdrug management.mp. 2. exp patient care team/ 3. exp delivery of health care, integrated/ 4. … drug surveillance.mp. 10. exp drug monitoring/ 11. 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 or 9 or 10
  15. S44 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s44.pdf
    October 01, 2007 - ARTICLE Designed Delays Versus Rigorous Pragmatic Trials Lower Carat Gold Standards Can Produce Relevant Drug … We simplified the PRT strategy by using designed delays (DD) to evaluate drug policies. … covering the elderly, the poor, and families with high drug expenditures, introduced a drug benefit … Periodic letters on evidence- based drug therapy improves prescribing: a randomized trial. … Randomized controlled trial of a drug policy change by British Columbia PharmaCare.
  16. effectivehealthcare.ahrq.gov/products/coronary-stents-outcomes/research
    February 10, 2010 - United States Food and Drug Administration. FDA Statement on coronary drug-eluting stents. … United States Food and Drug Administration. … Update to FDA statement on coronary drug-eluting stents. … Stent Thrombosis in Randomized Clinical Trials of Drug-Eluting Stents. … An Observational Study of Drug-Eluting Versus Bare-Metal Stents.
  17. Obesity (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/obesity_hi_impact.pdf
    April 17, 2012 - Naltrexone/bupropion combination drug is an oral, sustained-release drug intended to fight the body's … Food and Drug Administration (FDA). … Pharmaceutical companies struggle to develop a drug to treat obesity. … Lorcaserin: FDA issues complete response letter for Lorcaserin new drug application. … FDA accepts new drug application filing for Qnexa. [internet].
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-supplements_surveillance.pdf
    January 01, 2013 - Tufts University Boston, MA Katharine Lillie, MD Center for Drug Evaluation & Research, Food & Drug … Intermediate cardiovascular efficacy outcomes of cardiovascular drug(s) plus supplement versus drug(s … (drug-drug interactions) In August 2012, FDA reported an association between Lovaza and recurrent … Clinical or intermediate harms with cardiovascular drug(s) plus supplement versus drug(s) plus placebo … Pharmacokinetic outcomes with cardiovascular drug(s) plus supplement versus drug(s) plus placebo, no
  19. effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1506.pdf
    October 01, 2015 - Available: http://www.vrtx.com/current-projects/drug- candidates/vx-770.html. … Vertex's two-drug cystic fibrosis treatment shows promise. [internet]. … FDA panel backs Vertex cystic-fibrosis drug Orkambi. Wall Str J. 2015 May 12. … National drug list: drug list - three (3) tier drug plan. … HealthPartners PreferredRx: preferred drug list (formulary). [internet].
  20. #14 SUBSTANCE ABUSE (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1312.pdf
    December 01, 2013 - Opioid abuse is one of the most common forms of prescription drug abuse. … The company submitted a new drug application to the U.S. … Food and Drug Administration (FDA) in October 2012. … Anonymous and free prescription drug drop off program. [internet]. … Project Lazarus: an innovative community response to prescription drug overdose.

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