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Showing results for "drug".

1501. Disposition of Comments for Evidence Report 224 Omega-3 Fatty Acids (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/omega-3-maternity_disposition-comments.pdf
      October 12, 2016 - Food and Drug Administration, the American Dietetic Association and the Dietitians of Canada, the

1502. Self-Measured Blood Pressure: Future Research Needs (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/measuring-blood-pressure-future_research.pdf
      August 01, 2012 - Studies Effective Health Care Program Selection Criteria Appropriateness: • Represents a health care drug

1503. Methods Research Report: Performance and Usability of Machine Learning for Screening in Systematic Reviews (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-report-machine-learning-screening.pdf
      November 01, 2019 - unrecognized impaired visual acuity or vision-related functional limitations Intervention Any Food and Drug

1504. Continuous-Outcomes-Quantitative-Synthesis Methods (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/continuous-outcomes-quantitative-synthesis_methods.pdf
      March 01, 2011 - Methods Guide for Comparative Effectiveness Reviews Handling Continuous Outcomes in Quantitative Synthesis ii This report is based on research conducted by the Oregon Evidence-based Practice Center (EPC) under contract to the Agency for Healthcare…

1505. DEcIDE 34 - Developing a Registry of Patient Registries: Options for the Agency for Healthcare Research and Quality (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/registry-of-patient-registries-development_research_0.pdf
      February 01, 2012 - All efficacy drug trials conducted under Investigational New Drug applications for “serious or life-threatening … The trials are being conducted in all 50 states in the U.S. and in 167 countries.3 The Food and Drug … Food and Drug Administration Modernization Act of 1997, Public Law No. 105-115, 1997. 3. … Food and Drug Administration Amendments Act of 2007, Public Law 110-85. … Food and Drug Administration. U.S. Department of Health and Human Services. March 2002.

1506. An analytical framework for quantifying components of variability in prescriber decisions (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/instrumental-variable-methods_research.pdf
      April 01, 2010 - We anticipate that IV methods will be often underpowered for drug safety studies of very rare outcomes … The new drug is added to the formulary in some hospitals; however, because of cost and concerns about … Variation in formularies, hospital capacity, and prescription drug benefit plan structure can also … Pharmacoepidemiol Drug Saf 2009;18:932-940. 37. Korn EL, Baumrind S. … Drug copayment and adherence in chronic heart failure: effect on cost and outcomes.

1507. Cer-250-Cannabis-2025-Surv-Rep-Update-Tables-E1-4 (xls file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2025-surv-rep-update-tables-e1-4.xlsx
      January 01, 2025 - study enrollment Median 64 13 NR NR NR NR NR NR NR Patients with major psychiatric disorder or past drug … preparation Mean 50 23 NR NR NR NR NR Mean 48 Patients with bipolar disorder or psychosis excluded Comparison drug

1508. Disposition of Comments Report for Testing of CYP2C19 Variants and Platelet Reactivity for Guiding Antiplatelet Treatment (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_disposition-comments.pdf
      September 25, 2013 - However, clopidogrel metabolism is also influenced by drug-drug interactions such as PPIs, calcium channel … While concluding their argument, the authors ignored many important things including the role of drug-drug … We agree that drug-drug, gene-drug, or other interactions are potentially affecting the prognostic value … Ticagrelor is a direct drug although the active metabolite is as potent as native clopidogrel. … Therefore, it is important for measurement of the drug effect to be highly specific.

1509. Wheeled Mobility (Wheelchair) Service Delivery (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/wheelchair-service_technical-brief.pdf
      January 01, 2012 - Wheelchair safety—adverse reports to the United States Food and Drug Administration.

1510. Making Healthcare Safer IV_Rapid Response: Use of Report Cards and Outcome Measurements To Improve the Safety of Surgical Care (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-rapid-response-surgical-report-cards.pdf
      November 01, 2023 - Food and Drug Administration (FDA), and importantly, patients.

1511. Making Healthcare Safer IV_Rapid Review: Use of Structured Handoff Protocols for Intrahospital Within-Unit Transitions (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/structured-handoff-rapid-research.pdf
      January 01, 2025 - clinical outcomes (e.g., medical errors in general or specific safety events like mortality, adverse drug

1512. Acs-Pci-Adjunctive-Devices Surveillance (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/acs-pci-adjunctive-devices_surveillance.pdf
      April 01, 2013 - would produce prima facie evidence that a conclusion was out of date, such as the withdrawal of a drug … Is the portion of the CER that is probably or certainly out of date an issue of safety (a drug withdrawn … from the market, a black box warning) or the availability of a new drug within class (the latter being … original key questions, the conclusions of the original report, the results of the literature and drug … aspiration thrombectomy Vink, 20125 (PASSION) Post hoc analysis of RCT Patients being randomized to drug

1513. Layout 1 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-2007_executive.pdf
      January 01, 2007 - We assessed statistically each of the 66 possible drug comparisons of second-generation antidepressants … Direct evidence from head-to-head trials was considered sufficient to conduct meta-analyses for four drug-drug … Issues We found no studies that identified reliable predictors of individual responses to a specific drug … , many patients try multiple antidepressant medications before finding an effective, well-tolerated drug … , but predicting which drug will be most effective or best tolerated in any given individual is not yet

1514. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c_research-protocol.pdf
      November 30, 2011 - .); effects of dose and duration of therapy; and benefits and harms of different combinations of drug … Population(s):  Non-co-infected adults with HCV infection who have not had previous antiviral drug … US Food and Drug Administration. FDA approves Incivek for hepatitis C. … US Food and Drug Administration. FDA approves Victrelis for hepatitis C. … Drug Class Review on Pegylated Interferons for Hepatitis C. 2007.

1515. Layout 1 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation-ablation_executive.pdf
      July 01, 2009 - study in 1998, Haissaguerre and colleagues studied 45 patients with paroxysmal AF (PAF) refractory to drug … comparing 8 mm tip catheters to irrigated (closed or open) tip catheters in patients undergoing PVI for drug … There is a low level of evidence suggesting no differences in rhythm control in patients with drug- refractory … patients in each trial did not show significant differences in the outcomes of PVI in patients with drug-refractory

1516. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-disease-ace-inhibitor-arb-disposition.pdf
      March 10, 2010 - The EPC first looks at the universe of studies of ACE inhibitors and ARBs before assessing the two drug … One cannot assume that two different classes of drug are interchangeable, thus justifying combining … providing an initial analysis with both ACE inhibitors and ARBs and then providing them with each drug … - aldosterone system (RAAS) antagonists provide benefits and there are only two RAAS antagonistic drug … The initial and target doses vary for each drug, depending on whether it is used for HTN, HF, or left

1517. Comparative Effectiveness of Coronary Bypass Surgery and Percutaneous Coronary Interventions for Multivessel Disease: A Pooled Analysis of Individual Patient Data from Ten Randomized Trials (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-pci-bypass_addendum.pdf
      February 01, 2010 - As part of the Medicare Prescription Drug, Improvement, and Modernization Act of 2003, Congress directed … We have no data on concomitant drug treatment or on control of coronary risk factors during follow-up … None of the ten trials included in this study used drug-eluting stents for PCI. … stents,36 trials that compare CABG with PCI by use of drug-eluting stents are still in progress.33,37 … A hierarchical Bayesian meta-analysis of randomised clinical trials of drug-eluting stents.

1518. Menopause-Protocol-130612 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause-protocol-130612.pdf
      June 12, 2013 - Food and Drug Administration (FDA) in 1942 for treating menopausal symptoms, by 1947 the Physician’s … Food Drug Law J. 2008;63(2):459-91. PMID: 18561473. 22. Patsner B. … “therapy” [Subheading] OR “Therapeutics”[Mesh] OR “Estrogen Replacement Therapy”[Mesh] OR “Drug Therapy … effects” [Subheading]) OR “Drug Toxicity”[Mesh] AND (“Ovarian Neoplasms”[Mesh] OR “Breast Neoplasms … ”[Mesh] OR “Endometrial Neoplasms/drug therapy”[Mesh] OR “Endometrial Neoplasms/therapy”[Mesh]) 3

1519. Mental-Illness-Heart Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-heart_executive.pdf
      April 01, 2013 - identify relevant gray literature: (1) a request for scientific information packets submitted to drug … The drug classes in our review sometimes included drugs with diverse mechanisms of action. … When results varied by drug, we assigned separate SOE. … Impaired fasting glucose tolerance in first-episode, drug-naive patients with schizophrenia. … Pharmacoepidemiol Drug Saf. 2011;20(1):66-75. PMID: 21182154. 62.

1520. Disposition of Comments for Technical Brief 21, Management Strategies To Reduce Psychiatric Readmissions (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/psychiatric-readmissions_disposition-comments.pdf
      May 21, 2015 - schizoaffective>affective disorders, longer illnesses, higher antipsychotic doses and more complex drug-treatments