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effectivehealthcare.ahrq.gov/sites/default/files/infectious-disease-horizon-scan-high-impact-1412.pdf
December 22, 2014 - In October 2014, a new sofosbuvir drug
combination drug was approved (Harvoni; Gilead Sciences) that … It has also been approved as part of a fixed-dose
combination with the drug ledipasvir, a drug that … purportedly has a low drug-drug interaction profile, which could support its use in patients with … Gilead gets U.S. approval to sell
new hepatitis C drug: drug is seen building on
the highly successful … Food and Drug Administration (FDA).
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-psoriatric_executive.pdf
April 01, 2012 - 1
Comparative Effectiveness Review
Number 54
Drug Therapy for Psoriatic Arthritis in Adults:
Update … Food and Drug Administration (FDA)
has approved adalimumab, etanercept,
golimumab, and infliximab for … KQ 3: For patients with PsA, do drug therapies differ in
harms, tolerability, patient adherence, or … KQ 4: What are the comparative benefits and harms of
drug therapies for PsA in subgroups of patients … Drug Therapy for Psoriatic
Arthritis in Adults: Update of a 2007 Report.
-
effectivehealthcare.ahrq.gov/get-involved/nominated-topics/1-which-patients-benefit-the-most-from-mtm-services-11-which-factors-or-combinations-of-factors-are-most-predictive-of-the-clinical-benefit-of-mtm-services-111-disease-factors-eg-diabetes-vs-copd-multi-morbidity-vs-single-dis
July 28, 2010 - 2.2.What is the optimal timing of MTM services relative to events or diagnosis (e.g., initiation of drug … beneficiaries with 2 or more chronic conditions and high drug expenditures. … Appropriateness for EHC Program
Does your question include a health care drug, intervention, device … therapy by including provisions for medication therapy management (MTM) within the Medicare Part D drug … current eligibility criteria limit the inclusion of patients to those with multi-morbidity and high drug
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse-drug-therapy-surveillance.pdf
September 01, 2017 - 16 97
Anton61 2011 naltrexone,
acamprosate,
gabapentin
Medium 150 Largest for drug only 3 drug … Medium 150 Largest for drug 29 88
Naranjo69 1995 citalopram High 150 Largest for drug 64 149
Kranzler70 … Drug and alcohol dependence. 2013;133(2):440-446.
21. … Drug and alcohol dependence. 2013;133(2):754-758.
26. … The American journal of drug and alcohol abuse. 2017;43(3):324-331.
31.
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effectivehealthcare.ahrq.gov/sites/default/files/pulmonary_hi_impact.pdf
April 01, 2012 - to determine whether they are
potential candidates for the drug. … Food and Drug
Administration (FDA); 2010 Apr 9. 39 p. … Food and Drug Administration
(FDA); 2010 Apr 27. 35 p. … Available:
http://www.vrtx.com/current-projects/drug-
candidates/vx-770.html.
23. … /drug-candidates/vx-770.html
http://investors.vrtx.com/releasedetail.cfm?
-
effectivehealthcare.ahrq.gov/sites/default/files/ijzerman_ahrq-webinar-mcda.pdf
January 01, 2011 - pressure
high blood pressure
No adverse events
Out-of-Pocket Costs
5 US$
3 US$
5 US$
Drug … A
Drug B
Drug C
All MCDA and CA methods decompose a decision problem
into a set of criteria … pressure
high blood pressure
No adverse events
Out-of-Pocket Costs
5 US$
3 US$
5 US$
Drug … A
Drug B
Drug C
C1 = 0.5 C2 = 0.33 C3 = 0.17
L1.1 = 0.5
L1,2 = 0.25
L1,3 = 0.25
drug A
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-prevention_research-protocol.pdf
November 03, 2011 - Food and Drug Administration (FDA) for migraine prevention in
adults come from different drug classes … surveillance, or interactive drug monitoring. … , patient education, drug
surveillance, or interactive drug monitoring) influence results? … , patient education, drug surveillance, or interactive drug monitoring)
influence results? … Regulating off-label drug use--rethinking the role of the FDA.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/medication-therapy-management-1_research-2007.pdf
January 01, 2007 - Plans (PDP) and Medicare Advantage
Drug Plans (MA-PD). … Role of the clinical
pharmacist in improving drug therapy. … Fatal adverse drug events: the paradox of drug
treatment. J Intern Med 2001;250(4):327-41.
19. … Adverse drug events in emergency department
patients. … for and/or existence of drug-drug, drug-
disease, or drug-food interactions or problems)
55.0 5.6
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effectivehealthcare.ahrq.gov/products/rheumatoid-arthritis-medicine/research-protocol
December 06, 2010 - Protocol Jun. 1, 2012 Systematic Review Jun. 7, 2013 Surveillance Report Comparative Effectiveness of Drug … Food and Drug Administration (FDA) for the treatment RA at the time of the first review. … The Key Questions (KQs)
Question 1: For patients with RA, do drug therapies differ in their ability … Question 3: For patients with RA, do drug therapies differ in harms, tolerability, patient adherence … Food and Drug Administration (FDA).
-
effectivehealthcare.ahrq.gov/products/atypical-antipsychotics-off-label-update/research-protocol
May 19, 2010 - Objectives for the Systematic Review
Atypical antipsychotics are approved by the United States Food and Drug … To arrive at a quantitative measure, we will use the Jadad scale, which was developed for drug trials … The evidence of risks (adverse events) will be summarized within drug (each atypical antipsychotic separately … severely symptomatic persons have higher scores, a negative effect size indicates that the atypical drug
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-psoriatric_surveillance.pdf
March 01, 2013 - Psoriatic Arthritis Surveillance Assesment_CER 54_Low
CER #54:
Drug Therapy for Psoriatic Arthritis … Key Findings:
- Key Question 1: Conclusion regarding biologic Disease-
Modifying Antirheumatic Drug … This drug is
not approved for
PsA. … This drug is
not approved for
PsA.
EPC Investigator felt the
conclusions were up to date. … Drug Therapy for Psoriatic Arthritis in
Adults: Update of a 2007 Report.
-
effectivehealthcare.ahrq.gov/products/antipsychotics/research-protocol
September 06, 2018 - Currently, there are no medications approved by the Food and Drug Administration for the prevention and … Comparators:
KQ 1: Non-drug approaches to preventing delirium, placebo, active control, usual care … KQ 2: Non-drug approaches to treating delirium, placebo, active control, usual care
Outcomes: … For KQ 2, we will include non-drug approaches to treating delirium, including placebo, active control … Does antipsychotic drug use increase the risk of long term mortality?
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/medication-therapy-management_research-protocol.pdf
January 01, 2014 - Background and Objectives for the Systematic Review
The Medicare Prescription Drug, Improvement, … Public Law
108-173)1 established the requirements that Part D plan sponsors must meet with regard to drug … include providing education and counseling, improving medication adherence, and
detecting adverse drug … substitution issue; complex regimen that can
be simplified with same therapeutic benefit; and potential for drug-drug … : needed drug initiated; unnecessary drug discontinued; change
in drug dose, form, or frequency; or
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/acs-depression-research-protocol-amended.pdf
February 15, 2017 - Vilazodone: Drug Information. http://www.uptodate.com/contents/vilazodone-drug-
information? … Olanzapine: Drug Information. http://www.uptodate.com/contents/olanzapine-drug-
information? … Quetiapine: Drug Information. http://www.uptodate.com/contents/quetiapine-drug-
information? … Amoxapine: Drug Information. http://www.uptodate.com/contents/amoxapine-drug-
information? … Imipramine: Drug Information. http://www.uptodate.com/contents/imipramine-drug-
information?
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effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-fecal-incontinence.pdf
October 26, 2020 - 2020
1 ((anal or fecal or faecal) adj incontinen*).ti. (584)
2 (biofeedback or device* or diet* or drug … 2020
1 ((anal or fecal or faecal) adj incontinen*).ti. (15)
2 (biofeedback or device* or diet* or drug … incontinence OR fecal incontinence OR faecal incontinence ) AND ( biofeedback OR
device OR diet OR drug … Does the nomination represent a health care
drug, intervention, device, technology, or health
care … Abbreviations: CCFIS = Cleveland clinical fecal incontinence score; FDA = food and drug administration
-
effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-fecal-incontinence_2.pdf
October 26, 2020 - 2020
1 ((anal or fecal or faecal) adj incontinen*).ti. (584)
2 (biofeedback or device* or diet* or drug … 2020
1 ((anal or fecal or faecal) adj incontinen*).ti. (15)
2 (biofeedback or device* or diet* or drug … incontinence OR fecal incontinence OR faecal incontinence ) AND ( biofeedback OR
device OR diet OR drug … Does the nomination represent a health care
drug, intervention, device, technology, or health
care … Abbreviations: CCFIS = Cleveland clinical fecal incontinence score; FDA = food and drug administration
-
effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-fecal-incontinence_1.pdf
October 26, 2020 - 2020
1 ((anal or fecal or faecal) adj incontinen*).ti. (584)
2 (biofeedback or device* or diet* or drug … 2020
1 ((anal or fecal or faecal) adj incontinen*).ti. (15)
2 (biofeedback or device* or diet* or drug … incontinence OR fecal incontinence OR faecal incontinence ) AND ( biofeedback OR
device OR diet OR drug … Does the nomination represent a health care
drug, intervention, device, technology, or health
care … Abbreviations: CCFIS = Cleveland clinical fecal incontinence score; FDA = food and drug administration
-
effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-fecal-incontinence_0.pdf
October 26, 2020 - 2020
1 ((anal or fecal or faecal) adj incontinen*).ti. (584)
2 (biofeedback or device* or diet* or drug … 2020
1 ((anal or fecal or faecal) adj incontinen*).ti. (15)
2 (biofeedback or device* or diet* or drug … incontinence OR fecal incontinence OR faecal incontinence ) AND ( biofeedback OR
device OR diet OR drug … Does the nomination represent a health care
drug, intervention, device, technology, or health
care … Abbreviations: CCFIS = Cleveland clinical fecal incontinence score; FDA = food and drug administration
-
effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-fecal-incontinence_12.pdf
October 26, 2020 - 2020
1 ((anal or fecal or faecal) adj incontinen*).ti. (584)
2 (biofeedback or device* or diet* or drug … 2020
1 ((anal or fecal or faecal) adj incontinen*).ti. (15)
2 (biofeedback or device* or diet* or drug … incontinence OR fecal incontinence OR faecal incontinence ) AND ( biofeedback OR
device OR diet OR drug … Does the nomination represent a health care
drug, intervention, device, technology, or health
care … Abbreviations: CCFIS = Cleveland clinical fecal incontinence score; FDA = food and drug administration
-
effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-fecal-incontinence_11.pdf
October 26, 2020 - 2020
1 ((anal or fecal or faecal) adj incontinen*).ti. (584)
2 (biofeedback or device* or diet* or drug … 2020
1 ((anal or fecal or faecal) adj incontinen*).ti. (15)
2 (biofeedback or device* or diet* or drug … incontinence OR fecal incontinence OR faecal incontinence ) AND ( biofeedback OR
device OR diet OR drug … Does the nomination represent a health care
drug, intervention, device, technology, or health
care … Abbreviations: CCFIS = Cleveland clinical fecal incontinence score; FDA = food and drug administration