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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-off-label-update_research-protocol.pdf
May 19, 2010 - Objectives for the Systematic Review
Atypical antipsychotics are approved by the United States Food and Drug … To arrive at a quantitative measure, we will use the Jadad scale, which was developed for
drug trials2 … The evidence of risks (adverse events) will be summarized within drug (each atypical
antipsychotic separately … severely symptomatic persons have higher scores, a negative effect size
indicates that the atypical drug
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/assessing-applicability-quiz.ppt
September 02, 2013 - The impact of a drug on bone mineral density in young, male, well-trained astronauts in outer space may … The impact of a drug on bone mineral density in young, male, well-trained astronauts in outer space may … The impact of a drug on bone mineral density in young, male, well-trained astronauts in outer space may … The impact of a drug on bone mineral density in young, male, well-trained astronauts in outer space may
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effectivehealthcare-admin.ahrq.gov/sites/default/files/assessing-applicability-quiz.ppt
September 02, 2013 - The impact of a drug on bone mineral density in young, male, well-trained astronauts in outer space may … The impact of a drug on bone mineral density in young, male, well-trained astronauts in outer space may … The impact of a drug on bone mineral density in young, male, well-trained astronauts in outer space may … The impact of a drug on bone mineral density in young, male, well-trained astronauts in outer space may
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effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-238-cervical-ripening-appendix-e-1.xlsx
January 01, 2009 - Inpatient: After administration of the study drug a further minimum of 20 minutes or more of electronic … Outpatient: After administration of the study drug patients underwent 40 minutes of electronic fetal … After administration of study drug, all patients underwent continuous FHR monitoring for 3 hours. … There is no mention of fetal monitoring following the administration of the study drug. … Placebo (Provider NR)
-See protocol for intervention 1
NA NA All patients
Four hours after the drug
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/executive-summary-2017-schizophrenia-adult.pdf
January 01, 2017 - Both groups (treatment and usual
care) received usual care, including drug treatment
throughout the … Randomized controlled trials were evaluated with criteria
developed by the Drug Effectiveness Review … Overall, no drug intervention had
high-strength evidence for any outcome of interest, but we
found … Among illicit drug
users, differences between older SGAs were not found in
rate or time to drug discontinuation … Methods for the
drug effectiveness review project.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveillance-report-2.xlsx
September 30, 2015 - the trial did not indicate clear differences between treatments for pain, functioning, depression, or drug … Excluded patients with history of psychosis
Substance use: Excluded patients with history of illicit drug … stroke, and intracranial hemorrhage), major depression, cancer, and those without previous related drug … applicable; NR = not reported; NRS = numeric rating scale; NSAID = non-steroidal anti-inflammatory drug … ; OAT = opioid agonist therapy; OR = odds ratio; OUD = opioid use disorder; PDMP = prescription drug
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effectivehealthcare-admin.ahrq.gov/sites/default/files/ahrq-healthcare-horizon-scan-protocol-operations-manual_130826.pdf
August 01, 2013 - Is this a new molecular entity (drug), biologic, or device being developed for potential diffusion into … Is it subject to approval under FDA’s Investigational New Drug, Biologics Licensing, combination-
product … Is it a generic drug? If so, do not select, because these are “me-too” of existing drugs. … Does this appear to be a different/off-label use of an available drug, biologic, or device? … Is this a different delivery mode for an existing drug or device?
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/horizon-scan_research-protocol.pdf
December 01, 2011 - Is this a new molecular entity (drug), biologic, or generic formulation of a drug being developed
for … Is it a generic drug? If so, do not select, because these are “me-too” of existing drugs. … Does this appear to be a different/off-label use of a currently available drug, biologic, or device? … Is this a different delivery mode for an existing drug or device? … Potential Device/Drug Cost Per Patient (if applicable)
12.
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effectivehealthcare-admin.ahrq.gov/products/mental-illness-adults-prisons/research-protocol
December 01, 2019 - National Household Survey on Drug Abuse. The NHSDA report: serious mental illness among adults. … Drug therapy/
Exp antidepressive agents/
Psychotropic drugs/
Therapeutic use.fs. … EMBASE
Drug therapy.fs. … counseling
Drug therapy
Drug treatment/s
Drug-based
Incarceration-based drug treatment … therapy/ OR drug therapy.fs.
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effectivehealthcare-admin.ahrq.gov/products/mental-health-pregnancy/protocol
January 01, 2020 - Designing drug trials: considerations for pregnant women. … Food and Drug Administration. … Pharmacoepidemiol Drug Saf. 2013 Sep;22(9):1013-8. doi: 10.1002/pds.3495. PMID: 23893932. … Allergies" OR "Drug Dependency" OR "drug effects" OR "Drug Sensitivity" OR harm* OR harms OR "Long Term … Therapy"[Mesh] OR "drug therapy"[Subheading] OR drug*[tiab] OR pharmacotherap*[tiab] OR pharmacologic
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_disposition-comments.pdf
March 10, 2010 - Although any synthetic drug can be labeled "chemotherapy" in general,
medical, and oncologic parlance … The statement
that tamoxifen is the only drug evaluated in premenopausal women
has been added to this … US, was minimally evaluated and the
major study cited was stopped for an excess of strokes on the drug … Results I like the consistent presentation of results by drug (tam vs. ralox, tam vs. … We assumed that women take the drug for 5 years and NNT
estimates were calculated for a 5-year period
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/hepatitis-c-screening_executive.pdf
November 01, 2012 - The strongest risk factor for HCV
infection is injection drug use. … The prevalence of HCV
infection in injection drug users varies widely depending
on age, duration of … injection drug use, and other factors
(such as availability and use of needle exchange
programs).15 … Prevalences range from less than 50 percent
in more recent studies of younger injection drug users … Drug Alcohol Depend. 2009;105(1-2):160-3.
PMID: 19647375.
80.
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effectivehealthcare-admin.ahrq.gov/products/prostatic-hyperplasia-medications/research
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November 01, 2017 - Appropriateness for EHC Program
Does your question include a health care drug, intervention, device
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effectivehealthcare-admin.ahrq.gov/sites/default/files/arthritis_hi_impact.pdf
January 01, 2014 - Ann
estimated 750,000 gout patients initiate uric acid-lowering drug therapy in the U.S. annually. … The drug is a genetically engineered form of recombinant porcine urate oxidase, an enzyme
not found … Key Expert Comments: Overall, experts thought that the drug might address the unmet
need for a … Nat Rev Drug Discov 2009 Sep;8(9):688.
PMID: 19721439
79. Helms S, Darbishire PL. … Positive phase III results for benlysta as lupus
drug. Immunotherapy 2009 Sep;1(5):729.
85.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/urinary-incontinence-treatment_executive.pdf
April 01, 2012 - The drug
needed to be given to eight older patients to achieve
more than a 50 percent reduction in … Observational economic drug evaluations29,30 have
demonstrated greater absolute rates of treatment … We concluded that there was
a low risk of bias in the drug studies. … and nonpharmacological treatment modalities are superior
to mono-drug therapy. … Drug Saf. 2001;24(9):703-13. PMID 11522122.
25. Wang PS, Levin R, Zhao SZ, et al.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/psoriasis-chronic_disposition-comments.pdf
November 27, 2012 - Food and
Drug Administration (FDA) can be included
as per AHRQ. … Alefacept is no longer available; Astellas pulled the drug from the market in
December 2011. … Although
alefacept was voluntarily withdrawn from the
market by the manufacturer this year, the
drug … For inclusion/exclusion criteria, were
data obtained from drug manufacturers? … Food and Drug Administration (FDA) for psoriasis
treatment.”
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effectivehealthcare-admin.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1512.pdf
December 01, 2015 - Food and Drug Administration (FDA) in the first half of
2016. … Afrezza is also listed as a tier 5 drug
in some state Medicare drug plan formularies, which is the … Food and Drug Administration (FDA);
2012 Aug 3 [accessed 2012 Jun 18]. [2 p]. … Food and
Drug Administration (FDA); 2014 Jun 27
[accessed 2015 Jan 23]. [5 p]. … Food and
Drug Administration (FDA); 2014 Jun 30
[accessed 2015 Feb 09]. [5 p].
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effectivehealthcare-admin.ahrq.gov/sites/default/files/06_devdelays_potential_high_impact_2012-12-10.pdf
January 01, 2012 - similar drugs in the same class are read separately), and then topics in the same class of a
device, drug … This
drug is being investigated for off-label use.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1406.pdf
September 26, 2014 - The drug-device combination has been approved in Europe. … Food and Drug Administration (FDA). … Food and Drug Administration
(FDA); 2012 Nov 9. 63 p. … Food and Drug Administration (FDA). … Autoimmune Drug Focus; 2012 Oct 22.
1 p.
56.