-
effectivehealthcare-admin.ahrq.gov/sites/default/files/infectious-disease-horizon-scan-high-impact-1412.pdf
December 22, 2014 - In October 2014, a new sofosbuvir drug
combination drug was approved (Harvoni; Gilead Sciences) that … It has also been approved as part of a fixed-dose
combination with the drug ledipasvir, a drug that … purportedly has a low drug-drug interaction profile, which could support its use in patients with … Gilead gets U.S. approval to sell
new hepatitis C drug: drug is seen building on
the highly successful … Food and Drug Administration (FDA).
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/arthritis-psoriatric_executive.pdf
April 01, 2012 - 1
Comparative Effectiveness Review
Number 54
Drug Therapy for Psoriatic Arthritis in Adults:
Update … Food and Drug Administration (FDA)
has approved adalimumab, etanercept,
golimumab, and infliximab for … KQ 3: For patients with PsA, do drug therapies differ in
harms, tolerability, patient adherence, or … KQ 4: What are the comparative benefits and harms of
drug therapies for PsA in subgroups of patients … Drug Therapy for Psoriatic
Arthritis in Adults: Update of a 2007 Report.
-
effectivehealthcare-admin.ahrq.gov/products/methods-guidance-reporting-bias/methods
December 01, 2019 - Food and Drug Administration. … Drug Approval Process
Manufacturers are required to submit a New Drug Application to the FDA for all … The Drugs@FDA site may be searched by the generic or trade drug name (not drug class) for Statistical … Reporting bias in drug trials submitted to the Food and Drug Administration: review of publication and … Drug Effectiveness Review Project.
-
effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/migraine-patients-in-the-er-receive-various-iv-medications-from-different-er-doctors-within-the-physician-group-as-i-have-watched-particular-drug-combinations-given-to-my-patients-and-to-my-daughter-in-the-er-i-have-witnesse
November 01, 2017 - As I have watched particular drug combinations given to my patients and to my daughter in the ER, I have … As I have watched particular drug combinations given to my patients and to my daughter in the ER, I have … An older drug, DHE, an ergot, often causes nausea and additional anti nausea meds are then required. … Appropriateness for EHC Program
Does your question include a health care drug, intervention, device … As I have watched particular drug combinations given to my patients and to my daughter in the ER, I have
-
effectivehealthcare-admin.ahrq.gov/products/atypical-antipsychotics-off-label-update/research-protocol
March 01, 2020 - Objectives for the Systematic Review
Atypical antipsychotics are approved by the United States Food and Drug … To arrive at a quantitative measure, we will use the Jadad scale, which was developed for drug trials … The evidence of risks (adverse events) will be summarized within drug (each atypical antipsychotic separately … severely symptomatic persons have higher scores, a negative effect size indicates that the atypical drug
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pulmonary_hi_impact.pdf
April 01, 2012 - to determine whether they are
potential candidates for the drug. … Food and Drug
Administration (FDA); 2010 Apr 9. 39 p. … Food and Drug Administration
(FDA); 2010 Apr 27. 35 p. … Available:
http://www.vrtx.com/current-projects/drug-
candidates/vx-770.html.
23. … /drug-candidates/vx-770.html
http://investors.vrtx.com/releasedetail.cfm?
-
effectivehealthcare-admin.ahrq.gov/products/depression-pregnancy-postpartum/research-protocol
December 01, 2019 - that are compared with drug only interventions. … A vs. drug B)? … The combinations include:
Using a second drug to augment the effects of the primary drug and comparing … A vs. drug B)? … The combination include:
(a) Using a second drug to augment the effects of the primary drug and comparing
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/ijzerman_ahrq-webinar-mcda.pdf
January 01, 2011 - pressure
high blood pressure
No adverse events
Out-of-Pocket Costs
5 US$
3 US$
5 US$
Drug … A
Drug B
Drug C
All MCDA and CA methods decompose a decision problem
into a set of criteria … pressure
high blood pressure
No adverse events
Out-of-Pocket Costs
5 US$
3 US$
5 US$
Drug … A
Drug B
Drug C
C1 = 0.5 C2 = 0.33 C3 = 0.17
L1.1 = 0.5
L1,2 = 0.25
L1,3 = 0.25
drug A
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/migraine-prevention_research-protocol.pdf
November 03, 2011 - Food and Drug Administration (FDA) for migraine prevention in
adults come from different drug classes … surveillance, or interactive drug monitoring. … , patient education, drug
surveillance, or interactive drug monitoring) influence results? … , patient education, drug surveillance, or interactive drug monitoring)
influence results? … Regulating off-label drug use--rethinking the role of the FDA.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/medication-therapy-management-1_research-2007.pdf
January 01, 2007 - Plans (PDP) and Medicare Advantage
Drug Plans (MA-PD). … Role of the clinical
pharmacist in improving drug therapy. … Fatal adverse drug events: the paradox of drug
treatment. J Intern Med 2001;250(4):327-41.
19. … Adverse drug events in emergency department
patients. … for and/or existence of drug-drug, drug-
disease, or drug-food interactions or problems)
55.0 5.6
-
effectivehealthcare-admin.ahrq.gov/products/alzheimers-type-dementia/research
October 01, 2022 - cognitive impairment; biomarker accuracy for Alzheimer’s disease (AD) in dementia; and effects of CATD drug … Cholinesterase-inhibitors slightly outperformed placebo for cognition and function, but evidence of whether any drug
-
effectivehealthcare-admin.ahrq.gov/products/juvenile-arthritis-dmards/research
December 01, 2019 - There are few direct comparisons of DMARDs, and insufficient evidence to determine if any specific drug … or drug class has greater beneficial effects.
-
effectivehealthcare-admin.ahrq.gov/products/prevention-infection-mdro/protocol
September 01, 2023 - Making Healthcare Safer IV: Prevention of Transmission of Infection With Multi-Drug … Making Healthcare Safer IV: Prevention of Transmission of Infection With Multi-Drug … Review Questions
( Note: For the scope of this review, these multi-drug … Drug-resistant pathogens enter the healthcare environment from sources including infected patients (who … Project Timeline
Making Healthcare Safer IV: Prevention of Transmission of Infection With Multi-Drug
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/mhs-IV-rapid-response-deprescribing.pdf
February 01, 2024 - Few adverse
drug withdrawal events resulted from deprescribing interventions. … Adverse
drug events in ambulatory care. … Reducing Adverse Drug Events in Older
Adults. … Expert Opin Drug Saf.
2021 Jan;20(1):81-91. doi:
10.1080/14740338.2021.1853704. … Drug Ther Bull. 2023
May;61(5):69. doi: 10.1136/dtb.2023.000012. PMID: 36882298.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/arthritis-psoriatric_surveillance.pdf
March 01, 2013 - Psoriatic Arthritis Surveillance Assesment_CER 54_Low
CER #54:
Drug Therapy for Psoriatic Arthritis … Key Findings:
- Key Question 1: Conclusion regarding biologic Disease-
Modifying Antirheumatic Drug … This drug is
not approved for
PsA. … This drug is
not approved for
PsA.
EPC Investigator felt the
conclusions were up to date. … Drug Therapy for Psoriatic Arthritis in
Adults: Update of a 2007 Report.
-
effectivehealthcare-admin.ahrq.gov/products/medicine-safety-call-center/research
November 01, 2017 - An information technology architecture for drug effectiveness reporting and post-marketing surveillance … Abstract
Adverse drug events impose a large cost on the society in terms of lives and healthcare costs … this paper, we propose an information technology architecture for enabling the monitoring of adverse drug … The proposed system architecture enables the development of a web based drug effectiveness reporting … previous studies analyzing the involvement of community pharmacies in identifying and reporting adverse drug
-
effectivehealthcare-admin.ahrq.gov/health-topics/joint-disorders
May 24, 2017 - medlineplus.gov/jointdisorders.html
Products
Research Protocol May 24, 2017
Drug … for Knee Pain Secondary to Osteoarthritis
Systematic Review Archived June 1, 2012
Drug … Rheumatoid Arthritis in Adults: An Update
Systematic Review Archived June 1, 2012
Drug … Report
Research Protocol Archived December 6, 2010
Comparative Effectiveness of Drug … Arthritis
Systematic Review Archived November 19, 2007
Comparative Effectiveness of Drug
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/medication-therapy-management_research-protocol.pdf
January 01, 2014 - Background and Objectives for the Systematic Review
The Medicare Prescription Drug, Improvement, … Public Law
108-173)1 established the requirements that Part D plan sponsors must meet with regard to drug … include providing education and counseling, improving medication adherence, and
detecting adverse drug … substitution issue; complex regimen that can
be simplified with same therapeutic benefit; and potential for drug-drug … : needed drug initiated; unnecessary drug discontinued; change
in drug dose, form, or frequency; or
-
effectivehealthcare-admin.ahrq.gov/health-topics/bone-diseases
August 29, 2023 - for Treatment of Chronic Plaque Psoriasis
Systematic Review Archived June 1, 2012
Drug … Osteoporosis
Research Protocol Archived December 6, 2010
Comparative Effectiveness of Drug … Report
Research Protocol Archived December 6, 2010
Comparative Effectiveness of Drug … Osteoporosis
Systematic Review Archived November 19, 2007
Comparative Effectiveness of Drug
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/acs-depression-research-protocol-amended.pdf
February 15, 2017 - Vilazodone: Drug Information. http://www.uptodate.com/contents/vilazodone-drug-
information? … Olanzapine: Drug Information. http://www.uptodate.com/contents/olanzapine-drug-
information? … Quetiapine: Drug Information. http://www.uptodate.com/contents/quetiapine-drug-
information? … Amoxapine: Drug Information. http://www.uptodate.com/contents/amoxapine-drug-
information? … Imipramine: Drug Information. http://www.uptodate.com/contents/imipramine-drug-
information?