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digital.ahrq.gov/principal-investigator/jack-brian
February 28, 2023 - Investigator
Jack, Brian
Project Name
Virtual Patient Advocate to Reduce Ambulatory Adverse Drug … African American Women
Virtual Patient Advocate to Reduce Ambulatory Adverse Drug … Virtual Patient Advocate to Reduce Ambulatory Adverse Drug Events - Final Report. … Investigator
Jack, Brian
Project Name
Virtual Patient Advocate to Reduce Ambulatory Adverse Drug … Events
Virtual Patient Advocate to Reduce Ambulatory Adverse Drug Events - 2011
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digital.ahrq.gov/care-setting/across-health-care-system
January 01, 2023 - , Kathy
Huston, Paula
Enabling Shared Decision Making to Reduce Harm from Drug … graphically communicate risks and decision options, supporting SDM for patients and providers regarding drug-drug … Number
R01 HS026214
Principal Investigator(s)
Toh, Darren
Meaningful Drug … Interaction Alerts
Description
This research developed algorithms for eight key drug-drug
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digital.ahrq.gov/organization/oregon-state-university
January 01, 2023 - Oregon State University
Prescription Drug Monitoring Program Integration … Description
Results of this study align with the growing body of evidence that indicates that prescription drug … monitoring programs integration increases prescription drug monitoring programs use.
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digital.ahrq.gov/location/usa-or-corvallis
January 01, 2023 - USA, OR, Corvallis
Prescription Drug Monitoring Program Integration … Description
Results of this study align with the growing body of evidence that indicates that prescription drug … monitoring programs integration increases prescription drug monitoring programs use.
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digital.ahrq.gov/ahrq-funded-projects/rural-trial-clinic-order-entry-decision-support/annual-summary/2008
January 01, 2008 - Features of the prescription writer included on-the-fly drug-to-drug interaction prompts; automatic allergy … Drug-drug interaction checker : The drug-drug interaction checker displayed information about potential … drug-drug interactions above the electronic prescription pad. … Drug names color coded red indicated a major drug-drug interaction, purple indicated a moderate interaction … domains were studied, linked to the tool’s decision support features: medication safety (potential drug-drug
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digital.ahrq.gov/sites/default/files/docs/activity/u19hs021093-lambert-annual-summary-2012.pdf
January 01, 2012 - Food and Drug Administration. … Drug name confusion causes patients to receive the wrong drugs. … Consumers use drugs
unsafely because drug information is limited and confusing. … name confusion errors; and 4) patient-
centered, language-concordant drug information. … detection of drug errors at the hospital.
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digital.ahrq.gov/health-it-tools-and-resources/workflow-assessment-health-it-toolkit/research/tamblyn-r-et-al-2003
January 01, 2003 - [Link]
Abstract
"Background: Adverse drug-related events are common in the elderly, and inappropriate … therapeutic duplication by the study physician and another physician (RR 1.66, 95% CI 0.99-2.79) and drug … Interpretation: Computer-based access to complete drug profiles and alerts about potential prescribing … contraindications, 23 to drug interactions, 17 to drug-age contraindications, 3 to duration of therapy … This trend was evident for drug-disease contraindications, drug-age contraindications, excessive duration
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digital.ahrq.gov/sites/default/files/docs/better-medication-management-slides-021611.pdf
February 16, 2011 - directions
– Presence of contraindication
– Inappropriate duplicative therapy
– Important drug-drug … interaction
• Adverse drug events (ADEs)
– Injuries from drug therapy
• Preventable adverse drug … Incidence of adverse drug events and potential adverse drug events. Implications for prevention. … inappropriate therapy (3)
• Avoiding potentially inappropriate dosages (4)
• Avoiding potential drug-drug … orders and tell docs to re-enterdelay in care delivery
Standard alert signal & noise
• Drug-drug
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digital.ahrq.gov/sites/default/files/docs/citation/r01hs025375-zhou-final-report-2022.pdf
January 01, 2022 - Aim 3: Redesign drug allergy alerting mechanisms. … Drug allergies known to
cause adverse drug reactions (ADRs) account for 6 percent of hospitalizations … We included only drug class
allergens that comprised at least 0.5 percent of all reported drug allergies … We
found that drug matches are less likely to be overridden. … Drug-induced Anaphylaxis Documented in Electronic Health Records.
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digital.ahrq.gov/sites/default/files/docs/activity/virtual_patient_advocate_to_reduce_ambulatory_adverse_drug_events_2010_pdf__2.pdf
January 01, 2010 - Virtual Patient Advocate to Reduce Ambulatory Adverse Drug Events
1 | Virtual Patient adVocate to reduce … ambulatory adVerse drug eVents
2010 Grant Summary
Virtual Patient Advocate to Reduce Ambulatory … Adverse Drug Events
Principal Investigator: Jack, Brian, M.D. … findings, and conduct a randomized controlled trial (RCT) with subjects
who are at high risk of adverse drug … knowledge of self-care and medications,
2 | Virtual Patient adVocate to reduce ambulatory adVerse drug
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digital.ahrq.gov/sites/default/files/docs/activity/2011_017196_jack_pdf_3.pdf
January 01, 2011 - Virtual Patient Advocate to Reduce Ambulatory Adverse Drug Events
1 | Virtual Patient adVocate to reduce … ambulatory adVerse drug eVents
AmbulAtory SAfety And QuAlity: enAbling PAtient-Centered CAre through … heAlth it (r18)
Virtual Patient Advocate to Reduce Ambulatory Adverse
Drug Events
Principal Investigator … findings, and conducted a randomized controlled trial with
subjects who were at high risk of adverse drug … (Achieved)
2 | Virtual Patient adVocate to reduce ambulatory adVerse drug eVents
AmbulAtory SAfety
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digital.ahrq.gov/sites/default/files/docs/publication/uc1hs014882-ferranti-final-report-2008.pdf
January 01, 2008 - Automated Adverse Drug Event Detection and Intervention - Final Report … Adverse drug event (ADE) detection is a national priority. … drug-laboratory
combinations [5]. … A method for
estimating the probability of adverse drug reactions. … Computerized surveillance of adverse drug events in
hospital patients.
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digital.ahrq.gov/research-method/case-report
January 01, 2023 - Case Report
Evidence of clinically meaningful drug-drug interaction … Evidence of clinically meaningful drug-drug interaction with concomitant use of colchicine and clarithromycin … Drug Saf. 2020 Jul;43(7):661-668. doi: 10.1007/s40264-020-00930-7. PMID: 32274687. … Project Name
Meaningful Drug Interaction Alerts
A health system's pilot experience
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digital.ahrq.gov/ahrq-funded-projects/assessment-pediatric-look-alike-sound-alike-substitution-errors/annual-summary/2012
January 01, 2012 - Specific Aims:
Identify a subset of known LASA drug pairs that are prescribed in ambulatory pediatric … (Achieved)
Estimate frequencies of screening alerts (potential LASA substitution errors) in these drug … (Ongoing)
2012 Activities: The research team identified a subset of known LASA drug pairs that are … The team used a Food and Drug Administration (FDA) file that cross-referenced the brand name and generic … drugs that are the same drug but are listed under different names.
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digital.ahrq.gov/medical-condition/gastrointestinal-disease
January 01, 2023 - and Decision Aid for Patients with Crohn's Disease
Shared decision-making for drug-drug … interactions: Formative evaluation of an anticoagulant drug interaction. … Shared decision-making for drug-drug interactions: Formative evaluation of an anticoagulant drug interaction … Project Name
Enabling Shared Decision Making to Reduce Harm from Drug Interactions: An End-to-End
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digital.ahrq.gov/sites/default/files/docs/page/2006RaynerGorman_051911comp.pdf
May 25, 2011 - (FUROSEMIDE) 40mg QD PO 100
TOPROL XL 50MG qd PO 30 1 TAB
MECLIZINE HCL 25MG tid PO 270 1 TAB
Drug … • Basic approach: “Look-up table” that
translates from drug name (as listed) to
standard identifier … • Advanced approach: parsing of drug name
string, recognition of lexical elements,
combination … for drug products
• data reported by producers
• National Drug File - Reference Terminology
• also … in UMLS Metathesauraus
• designated as standard for drug classifications
• maintained by VA
6
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digital.ahrq.gov/health-it-tools-and-resources/workflow-assessment-health-it-toolkit/research/kaushal-r-et-al-2003
January 01, 2003 - trial, or an observational study with controls and if the measured outcomes were clinical (e.g. adverse drug … corollary orders, 1 an improvement in 5 prescribing behaviors, and 1 an improvement in nephrotoxic drug … , and more sophisticated CDSSs can perform drug allergy checks, drug-laboratory value checks, and drug-drug … about corollary orders (e.g. prompting the user to order glucose checks after ordering insulin) or drug … Basic CDSSs often assist in tasks such as drug selection, dosing, and duration, and more refined CDSSs
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digital.ahrq.gov/sites/default/files/docs/publication/r03hs018841-basco-final-report-2013.pdf
January 01, 2013 - A for drug B, or drug B for drug A in
any pair). … : The drug patient received in error
† Intended Drug: The drug patient was supposed to receive
‡ Average … Intended
Drug*
Delivered
Drug†
Average
Harm
Score‡
Number
of
Subjects§
Intended
Drug … : The drug patient was supposed to receive
† Delivered Drug: The drug patient received in error
‡ … : The drug patient was supposed to receive
† Delivered Drug: The drug patient received in error
‡
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digital.ahrq.gov/organization/washington-university
January 01, 2023 - HS024767
Principal Investigator(s)
Yen, Po-Yin
Surveillance for Adverse Drug … Principal Investigator
Bailey, Thomas
Project Name
Surveillance for Adverse Drug … Events in Ambulatory Pediatrics
Surveillance for Adverse Drug Events in Ambulatory … project team successfully developed and implemented an automated system for measuring the rate of adverse drug
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digital.ahrq.gov/research-method/systematic-review
January 01, 2024 - Name
Clinical Decision Support Innovation Collaborative (CDSiC)
Overriding drug-drug … Overriding drug-drug interaction alerts in clinical decision support systems: A scoping review. … Project Name
Meaningful Drug Interaction Alerts
Smart glasses for supporting … Project Name
Preventing Perioperative Medication Errors and Adverse Drug Events Through the Use of