-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-urinary-retention_research-protocol.pdf
November 19, 2012 - controlled trials using an instrument we develop
based upon the Cochrane Risk of Bias tool.10 The seven domains … outcome data, selective reporting, and other sources of bias
(i.e., problems not covered by other domains … symptom or quality of life
scale scores) within each comparison will be evaluated based on four required domains … an estimate).13 A fifth domain, reporting bias, will be assessed when SOE based
upon the first four domains
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/joint-replacement-disposition-comments.pdf
November 03, 2021 - reviewers asked for more details in approaches
used for grading the strength of evidence and how certain domains
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/meditation_research-protocol.pdf
October 17, 2012 - a
range of important outcomes related to stress and well-being.5 The selected outcomes fall into domains … Conducting Comparative Effectiveness Reviews.29 In assigning evidence grades we
will consider the domains … We will also consider additional domains such as biological plausibility, dose-response
effect and, … Conducting Comparative
Effectiveness Reviews.29 In assigning
evidence grades we will consider the
domains … We will
also consider additional domains such
as biological plausibility, dose-
response effect and
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-difficile-update_research-protocol.pdf
December 23, 2014 - For diagnostic studies, we will use the QUADAS 2 tool.28 Risk of bias domains
include patient selection … between medium and high risk of
bias will be determined by nuances in study conduct across the four domains … The seven domains included in this tool include sequence generation, allocation
concealment, blinding … evidence for primary outcomes of KQ1 within each
comparison will be evaluated based on five required domains … the overall body of
evidence will take into consideration the differences in strength of evidence domains
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-194-disposition-comments-inhaled-corticosteroids.pdf
March 19, 2018 - The specific domains which
contributed to the downgrading of
all outcomes, organized per KQ,
appear … Further description
as to the domains that led to
downgrading a given outcome are
provided in the … The five
contributing domains include risk
of bias, consistency, directness,
precision and publication … ROB was taken into
account when SOE was graded,
as one of the domains. … ROB was taken into account when
SOE was graded, as one of the
domains.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/urinary-incontinence-treatment_surveillance.pdf
October 29, 2012 - 95% CI= 0.54, 5.84; p<0.000116
No Signal
Quality of life based on King’s Health Questionnaire domains … We
identified one RCT that demonstrated significant differences in three domains of quality of life … We identified one RCT that demonstrated significant
differences in two domains of quality of life measure … Darifenacin
Darifenacin significantly improved
urgency UI and several domains of
quality of life more … Darifenacin
Darifenacin significantly improved urgency UI and several
domains of quality of life more
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/bimp-protocol.pdf
September 27, 2022 - randomized trials for
Key Questions 1 and 2 using the Cochrane Risk of Bias 2 (ROB2) tool.13 The five domains … study
and assign a risk of bias rating of “high,” “some concerns,” and “low” for each of the above
domains … The primary
domains assessed include risk of bias, directness, consistency, precision, and reporting … Additional domains may be used when appropriate, including dose-response association, strength
of association … Below, we discuss the primary domains and how we will assess them:
Risk of bias (see the above section
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/patient-safety-practices_research-protocol.pdf
November 09, 2011 - Measure high-priority contexts in the 4 domains
a) External factors, such as regulatory requirements … develop this with the TEP as the project develops, but it will take into
consideration a number of domains
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/fecal-incontinence_research-protocol.pdf
November 30, 2014 - For RCTs, we will assess the risk of bias using a modified Cochrane Risk of Bias tool.37 The
seven domains … data, selective
outcome reporting, and other sources of bias (i.e., problems not covered by other domains … Moderate risk of bias will
be assigned to studies that are challenged across several of the domains … as moderate or
higher, intervention-outcome pairs need a positive response on two out of the three domains … For prior systematic reviews that provided acceptable strength of evidence, strength of
evidence domains
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/major-depressive-disorder_clinician.pdf
September 01, 2016 - .
** The overall evidence grade was assessed based on the ratings for the following domains: study limitations … Other domains that were considered, as appropriate, included dose-response association, plausible
confounding
-
effectivehealthcare.ahrq.gov/products/methods-guidance-tests-bias/slides
-
effectivehealthcare.ahrq.gov/sites/default/files/assessing-applicability.ppt
January 01, 2009 - substantiate its importance
To delineate a systematic approach to assessing applicability by using PICOS domains … To recognize common features that may impact the applicability of studies
PICOS domains = population … substantiate its importance, delineate a systematic approach to assessing applicability by using PICOS domains … Finally, given the information on the PICOS domains, the judgment that this is an efficacy trial is made … For our purposes, assume that four other studies were also available with similar PICOS domains.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/multiple-sclerosis_research-protocol.pdf
December 17, 2013 - literature, using an instrument we develop based upon the Cochrane Risk of Bias tool.11
The seven domains … outcome data, selective reporting, and other sources of bias (i.e., problems not
covered by other domains … to sustained disease progression) within each
comparison will be evaluated based on four required domains … an estimate).16 A fifth domain, reporting bias, will be assessed when
SOE based upon the first four domains
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/long-term-care-adults_research-protocol.pdf
December 20, 2011 - We will compare across settings characteristics of
those served in the domains of physical function … We will compare results across settings for
specific outcome domains. … In brief, the EPC approach requires assessment of four domains:
Risk of bias (internal validity) … We will evaluate individual
domains listed above qualitatively and assess a summary rating of “high
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hypertension-pulmonary-arterial_research-protocol.pdf
January 30, 2013 - QUADAS-2
describes risk of bias in four key domains: patient selection, index test(s), reference
standard … Results will be described for
individual domains. … If the distribution of ratings permits, methodological domains will
be examined for association with … Additional domains are to be used when
appropriate: coherence, dose-response association, impact of … These
domains will be considered qualitatively, and a summary rating of “high,” “moderate,” or
“low
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/head-neck-cancer_surveillance.pdf
August 01, 2012 - the body of evidence is moderate
for IMRT reducing late xerostomia and improving
quality-of-life domains … Quality of life was reported in three observational
studies and generally favored IMRT in domains … the body of evidence is moderate
for IMRT reducing late xerostomia and improving
quality of life domains … shows that greater
conformality of radiation reduces late xerostomia
and improves quality-of-life domains … the body of evidence is moderate for
IMRT reducing late xerostomia and improving
quality-of-life domains
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/pwd-care-interventions-protocol.pdf
February 22, 2019 - rated using
modified Cochrane risk of bias tools as high, medium, or low for each of the following
domains … For these complex interventions, risk of bias will include
domains similar to those outlined in a risk … select outcomes for KQs 1 through 10 within
each comparison will be evaluated based on five required domains … studies
were randomized controlled trials with a low risk of bias, with consistent, direct, and
precise domains … NIH Stage Assessment Tool
Table: PRECIS-2 scores for trial domains, with modification for Care Delivery
-
effectivehealthcare.ahrq.gov/sites/default/files/braddock.pdf
January 01, 2011 - Slide 12: Medical Decision Making
Domains
Domain
Basic
Decisions
Intermediate
Decisions
Complex
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-bias_methods.pdf
July 01, 2012 - An updated
version of this scale, called QUADAS-2, identifies four key domains (patient selection, index
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-screening_executive.pdf
April 01, 2012 - studies using a modified version of the
Newcastle Ottawa Scale.11 The Newcastle Ottawa Scale
includes domains … assessment for diagnostic accuracy
studies.12 The QUADAS tool includes 14 items that
evaluate numerous domains … The authors
also note that no studies were at low risk of bias for all
of the modified QUADAS domains … without knowledge of the candidate test(s) in 44 percent
of included studies, but we judged these domains