-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/undescended-testicle_research-protocol.pdf
September 02, 2011 - , the Cochrane Collaboration’s tool for
assessing risk of bias will be employed.
14
Fundamental domains … Effectiveness and Comparative Effectiveness
Reviews,
17
which emphasizes the following four major domains … comparison of interest will be given an overall
evidence grade based on the ratings for the individual domains
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-cancer-screening_research-protocol.pdf
May 18, 2011 - Effectiveness and Comparative Effectiveness Reviews.
17
The grade will be based on four
major domains … Additional domains—such as dose-response association, plausible confounding, strength
of association … applicability for each outcome (including harms) will be performed
separately from assessments of the other domains
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_executive-2016.pdf
January 01, 2016 - Quality “Methods Guide for
Effectiveness and Comparative Effectiveness Reviews”10
and considered all domains … having low study limitations
if most (51% or greater) of the studies scored positive in
all five domains … considered high grade if study
limitations were low and there were no problems in any
of the other domains
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/head-neck-cancer-update_executive.pdf
December 01, 2014 - Treatment with IMRT showed a
benefit in some general QOL domains, as well as several
domains specific … General domains in which IMRT demonstrated
a significant benefit included emotional functioning at … No
QOL domains were worse with IMRT than 3DCRT at
any timepoint. … For both RT techniques, QOL domains
generally experienced maximal deterioration after RT,
followed … Other domains (pain, appearance, activity,
recreation, swallowing, chewing, speech, shoulder, taste,
-
effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1512.pdf
December 01, 2015 - Investigators in basic science and clinical research domains continue to probe
model systems and patient
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-adults_research-protocol.pdf
December 01, 2010 - When compared to FGAs, SGAs
have shown greater benefits in many outcome domains,9 and newer medications … will be assessed by using the Cochourane
Collaboration Risk of Bias tool.21 This tool consists of six domains … The overall assessment
is based on the responses to individual domains. … If one or more individual domains are
assessed as having a high risk of bias, the overall score will … This approach assesses the evidence based on four domains: risk of bias, consistency,
directness, and
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/public-reporting-cost-measures_disposition-comments.pdf
March 05, 2015 - I think it would be helpful to the
reader to add a sentence that lists the sub domains of PRICE, and … of this framework and analysis of
the relative importance of each domain, and each criteria within domains … Reviewer #6 Findings Rather than Figure 2 as it is now summed across all five domains, I think it would … Especially because certain
of these domains are, I think, more important to the site being useful and
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-introduction_methods.pdf
July 01, 2012 - Methods Guide for Medical Test Reviews Chapter 1
1-1
Chapter 1
Introduction to the Methods Guide
for Medical Test Reviews
David B. Matchar, M.D., FACP, FAHA; Duke-NUS Graduate Medical School Singapore;
Duke University Medical Center, Durham, NC
Abstract
Evaluation of medical tests presents cha…
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/safety-vaccines-protocol.pdf
January 30, 2020 - The current CTCAE system (version 5)
differentiates 837 adverse events within 26 adverse event domains … reporting are often lacking in rigor; thus,
we will apply critical appraisal criteria assessing two main domains … The strength of evidence
domains are compatible with the GRADE group’s criteria to downgrade the quality … Common Terminology Criteria for Adverse Events
classification system (CTCAE) adverse event domains … Common Terminology Criteria for Adverse Events classification system (CTCAE) adverse event domains
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mass-casualty-events-scarce-resources_executive.pdf
June 01, 2012 - Effectiveness and
Comparative Effectiveness Reviews.12 That approach
requires assessment in four domains … After making
assessments in these four domains, we graded the strength
of the evidence using the four-point … Most, but not all, of these plans
described strategies that fit into one or more of four
overarching domains … No State plan addressed all four domains.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/celiac-disease_clinician.pdf
July 01, 2016 - * The overall evidence grade was assessed based on the ratings for the following domains: study limitations … Other
domains that were considered, as appropriate, included dose-response association, plausible confounding
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ems-blood-transfusion-protocol-amendment.pdf
February 04, 2025 - 5 based on the recommendations given in AHRQ Methods Guide.12
The assessment will consider several domains—the … In case they are relevant, additional domains, such as dose-response association and
strength of association … insufficient according to a four-level scale by evaluating and
weighing the combined results of the included domains … Below, we discuss the primary domains and how we will assess them:
Risk of bias (see the above section
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-behavior-programs_research-protocol.pdf
June 05, 2014 - The overall assessment is based on the responses to individual domains. … If one or more
individual domains has a high risk of bias, we will rate the overall score as high risk … We will examine five core domains: study limitations or risk of bias, consistency, directness,
precision … We will also consider additional domains such as dose-response
association, plausible confounding, and … For all domains we will describe the
logic and rationale for our judgments.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/trauma-informed-care-protocol.pdf
April 19, 2023 - For CQs, we will use a thematic approach, noting the principles and domains of the models
and then cross-walking … We will note
the presence or lack of consistency principles, domains, and the intervention components … overall strength of evidence for outcomes for KQs 1-2 within each
comparison, based on five required domains
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/disruptive-behavior-disorder_research-protocol.pdf
January 30, 2014 - The tool includes six items from five domains of
potential sources of bias (i.e., selection, reporting … The required domains for grading the strength of evidence are: study limitations
(previously named risk … A set of domains supplement the five
required domains: dose-response association, plausible confounding … These additional domains are most relevant to
bodies of evidence consisting of observational studies … When scoring the individual domains, we will reference the definitions and scores
outlined in the AHRQ
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/documentation-burden-protocol.pdf
July 26, 2023 - documentation burden must accurately reflect these important differences, and assessment of
validity in the domains … Collating and assessing evidence across these domains will inform efforts by health systems and
standard-setting
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/deficit-hyperactivity-protocol.pdf
November 01, 2021 - bias in intervention
studies adapted for the eligible study designs.92, 93
QUADAS 2 evaluates four domains … In determining the strength of a body of evidence, the following domains will be
evaluated:
• Study … strength of evidence grade will be assigned by evaluating and weighing the
combined results of the above domains … Summary tables will include ratings for individual strength of evidence domains (i.e., risk
of bias, … Subthreshold attention-deficit/hyperactivity
disorder is associated with functional impairments across domains
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/labor-nitrous-oxide_research-protocol.pdf
August 24, 2011 - For randomized controlled trials, the fundamental
domains will include: adequate sequence generation … evaluation will be that stipulated in the EPC Methods Guide
8
, which
emphasizes the following four major domains … comparison of interest will be given an overall
evidence grade based on the ratings for the individual domains
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cystic-fibrosis-hgh_research-protocol.pdf
August 22, 2008 - Two investigators will
independently grade each outcome using required domains, comprising 4 major constructs … The domains will include, but may not be limited
to: risk of bias, consistency, directness, and precision … We will then use the subsequent domains to
modify the overall grade.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/nppv-respiratory-failure_research-protocol.pdf
April 21, 2011 - described in the General Methods
Guide.
20,22
In brief, the approach requires assessment of four domains … Additional domains are to be used when appropriate: coherence, dose-
response association, impact of … These domains will be considered qualitatively, and
a summary rating of “high,” “moderate,” or “low