-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/long-term-care-adults_executive.pdf
November 01, 2012 - We aggregated all relevant outcome measures
within a particular outcome domain and evaluated
strength … Because
many possible outcome measures may be used within
one domain, and because all included studies … measures, the precision score
also reflected how fully the set of outcome measures
described the outcome domain … Summary of key findings and strength of evidence for outcome domains
Domain/Outcome Key Findings/Strength
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/celiac-disease_research-protocol.pdf
June 12, 2014 - Risk: Low/High/Unclear
Domain 2: Index Test(s) (complete for each index test used)
Were the index … Risk: Low/High/Unclear
Domain 3: Reference Standard
Is the reference standard likely to correctly … Risk: Low/High/Unclear
Domain 4: Flow and Timing
Was there an appropriate interval between index test … If we
feel that their methods are inadequate or do not address an important domain, we will re-
Source … Required and additional domains and their definitions
Domain Definition and Elements Application to
-
effectivehealthcare.ahrq.gov/products/methods-guidance-tests-bias/methods
-
effectivehealthcare.ahrq.gov/sites/default/files/tech-brief-39-pediatric-cancer-survivorship-comments.pdf
March 01, 2021 - There are lots of papers
examining outcomes in the biomedical and
psychosocial domain (many of them … KI Reviewer
#4
Methods Figure 2. on page 17 showed a great
representation through each domain and … Figure 6 and Guiding Question 4, recommend
adding some example strategies under each of
the sub-domain … Should it be included as an intermediate
outcome in the survivorship care domain? … For GQs 1 and 2, knowledge of
survivorship care was included
as part of the Survivorship
Outcome Domain
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-introduction_methods.pdf
July 01, 2012 - detailed description of each included framework, the reader is referred to the original references.16–19
Domain … 1—analytical validity; Domain 2—clinical validity; Domain 3—clinical utility; Domain 4—ethical, legal … Public domain notice: This document is in the public domain and may be used and reprinted
without permission
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-health-app-protocol-updated.pdf
January 01, 2018 - from KI perspectives, including
identifying gaps and providing recommendations to strengthen each domain … For each
abstracted domain, the relevance to this project will be discussed and determined
among the
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-protocol-amended.pdf
February 07, 2025 - details (including type,
dosage, and frequency), details for relevant outcomes (including outcome domain … outcome data
• Bias in measurement of the outcome
• Bias in selection of the reported result
Each domain … questions which inform the judgment of risk of
bias as “low,” “some concerns,” or “high” for that domain … outcome data
• Bias in measurement of the outcome
• Bias in selection of the reported result
Each domain … which inform the judgment of risk of
bias as “low,” “moderate,” “serious,” or “critical” for that domain
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/catd-protocol-draft_0.pdf
November 02, 2018 - criteria.8, 9 These criteria require acquired, persistent impairment
in memory and another cognitive domain … batteries)
Single domain tests
(memory, executive,
language, attention
Biomarker tests:
Brain … (brief global screens, short multi-domain batteries, individual domain tests
[memory, executive, language … Attention is a nonspecific cognitive domain for diagnosis of CATD
and underlying Alzheimer’s disease … ASSESSMENT GUIDANCE
Domain Assessment Options
1.
-
effectivehealthcare.ahrq.gov/sites/default/files/assessing-the-risk-of-bias_draft-report.pdf
June 02, 2011 - Risk of bias (study
conduct)/internal validity
Yes No Yes (required domain of
risk of bias)
Precision … Only when no quantitative
pooling or presentation is
possible
No Yes (required domain of
precision … of differences
between outcomes listed
full protocol and published
materials
Yes Yes (optional domain … arms)
Yes (applicability of
choice of outcomes)
Yes (directness of
measures under required
domain … of
risk of bias)
Fidelity to protocol Yes No No
Conflict of interest No No Yes (optional domain
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/white-paper-lumbar-spondylolisthesis.pdf
March 01, 2021 - OUTCOME
MEASURE DEFINITION
Patient Reported Pain interference
Pain interference, using PROMIS domain … Patient Reported Physical function & mobility Physical function & mobility, using PROMIS domain or Oswestry … Psychological well-being
(depression/anxiety)
Psychological well-being (depression/anxiety), using PROMIS domain
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/white-paper-lumbar-spondylolisthesis.pdf
March 01, 2021 - OUTCOME
MEASURE DEFINITION
Patient Reported Pain interference
Pain interference, using PROMIS domain … Patient Reported Physical function & mobility Physical function & mobility, using PROMIS domain or Oswestry … Psychological well-being
(depression/anxiety)
Psychological well-being (depression/anxiety), using PROMIS domain
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-postpartum-screening_executive.pdf
May 01, 2013 - The questions in each
domain are rated in terms of risk of bias and concerns
regarding applicability
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tethered-spinal-cord-protocol.pdf
July 19, 2023 - • Reference standard: The domain reference standard evaluates whether the
reference standard, its … • Flow and timing: The last domain, flow and timing, evaluates whether the conduct
of the study … For
each domain, we assessed the potential risk of bias in the study in order to identify
high risk … Consistent with QUADAS-2,11 the
critical appraisal will evaluate for each study and appraisal domain … The domain is graded as direct or indirect.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/search-strategy-white-paper.pdf
February 01, 2025 - (details on creating the domains appear below, and domain assessment criteria are listed
in full in … Reviewers indicated whether tools met all/most domain criteria, met half of the domain criteria,
met … less than half of the domain criteria, or was not available at the time of review/did not meet
any … domain criteria. … ✓ = met half of the domain criteria
✓- = met less than half of the domain criteria
X = was not
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/masks-prevention-covid-healthcare-community-amended-protocol.pdf
July 02, 2020 - Prevention of COVID-19 in Healthcare
and Community Settings
(Amended July 2, 2020)
Condition or Domain … appendix-vi-criteria-assessing-internal-validity-individual-studies
Evidence-based Practice Center Living Rapid Review Protocol
Condition or Domain
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/head-neck-cancer_executive.pdf
May 01, 2010 - Layout 1
Background
Head and neck cancers, specifically those
arising in the oral cavity, larynx,
hypopharynx, oropharynx, nasopharynx,
paranasal sinuses/nasal cavity, salivary
glands, and occult primaries, account for
approximately 3 to 5 percent of cancers in
the United States. According to the
National Comprehens…
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/patient-centered-medical-home_executive.pdf
July 01, 2012 - –
Risk of Bias:
Study Design/
Quality
SOE
Domain–
Consistency
SOE
Domain–
Directness
SOE … Domain–
Precision
Effect Estimate
(Range or
95% CI)
Patient Experiences
[Moderate SOE: small … KQ 1 (continued)
Outcome [SOE
& Magnitude of
Effecta,b,c]
Number
of Studies
(Subjects)
SOE Domain … –
Risk of Bias:
Study Design/
Quality
SOE
Domain–
Consistency
SOE
Domain–
Directness
SOE … mean difference; SOE = strength of
evidence
For KQ 1a, there were too few studies in each outcome domain
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hro-protocol.pdf
January 01, 2023 - Context and Domain Being Studied
The Agency for Healthcare Research and Quality (AHRQ) Making Healthcare … procedure-manual-appendix-vi-criteria-assessing-internal-validity-individual-studies
Evidence-based Practice Center Rapid Review Protocol
Review Questions
Context and Domain
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/integrating-evidence_methods.pdf
February 01, 2015 - This document is in the public domain and may be used and reprinted without permission except
those … Because the RoB is ultimately collapsed to study limitations
domain categories of high, medium or low … grading criteria
If using existing review’s grading, the methods need to be transparent
Once one domain
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-treatment-ssri_surveillance.pdf
January 01, 2013 - Domains with the greatest
variability included domain 3 (rigor of
development), domain 5 (applicability … ), and
domain 6 (editorial independence). … Domains with the greatest variability
included domain 3 (rigor of development),
domain 5 (applicability … ), and domain 6
(editorial independence).