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effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-options-summarizing.ppt
June 01, 2012 - Example: The disease, such as psoriatic arthritis, is complex. … Index and reference tests are correlated within strata of disease. … It provides data on sensitivity, specificity, and disease prevalence. … Estimating disease prevalence in the absence of a gold standard. … Estimating disease prevalence in the absence of a gold standard.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/single-group-studies_white-paper.pdf
January 01, 2013 - For example, in
patients with end-stage liver disease, the natural history of disease is so well known … On the other hand, single group studies of interventions for
diseases with stable or steadily progressing … Similarly, if symptoms fluctuate over the course of disease, the exacerbation of
symptoms may drive … However, for some diseases with an apparently uniformly poor prognosis, there
may be subtle yet clinically … For diseases with an
unpredictable or variable natural history, a strong rationale must be available
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effectivehealthcare.ahrq.gov/sites/default/files/assessing-applicability.ppt
January 01, 2009 - prevalence in study population different than community Prevalence of disease (for diagnostic studies … Finally, evaluate the prevalence of the disease in diagnostic test studies. … If the disease prevalence is markedly different than in the community, then applicability is reduced. … This is especially true in diseases that afflict patients with lower compliance rates such as abusers … In this example, we focus on the age of patients with a disease.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/colon-cancer-gene-profiling_technical-brief.pdf
December 01, 2012 - will develop recurrence or die from their disease. … generally measured by disease-free survival. … Clinical Validity (Diagnostic Accuracy)
How is recurrence defined, e.g. local disease, distant disease … o For disease-free survival, how was it determined? … Diseases of the Colon & Rectum. 2005 Dec;48(12):2238-48. PMID:
16228831.
4.
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effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-genetic.ppt
June 01, 2012 - Centers for Disease Control and Prevention. Public Health Genomics. Genomic Testing. … Centers for Disease Control and Prevention. Public Health Genomics. Genomic Testing. … Is it used to determine the future risk of disease in asymptomatic individuals? … In addition, when numerous polymorphisms are tested for associations with diseases or outcomes, as in … Many genetic variants identified that are thought to influence susceptibility to diseases are eventually
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-genetic.ppt
June 01, 2012 - Centers for Disease Control and Prevention. Public Health Genomics. Genomic Testing. … Centers for Disease Control and Prevention. Public Health Genomics. Genomic Testing. … Is it used to determine the future risk of disease in asymptomatic individuals? … In addition, when numerous polymorphisms are tested for associations with diseases or outcomes, as in … Many genetic variants identified that are thought to influence susceptibility to diseases are eventually
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-screening_executive.pdf
November 01, 2012 - , the Infectious
Diseases Society of America, and the American College
of Gastroenterology) recommend … Center for Disease Control; 2011. … Committee on Infectious Diseases. Pediatrics. 1998;101(3):481-5.
PMID: 9499195.
43. … Clinical infectious diseases : an official publication of the
Infectious Diseases Society of America … Meta-analyses of FibroTest
diagnostic value in chronic liver disease.
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effectivehealthcare.ahrq.gov/products/ischemic-stroke-treatment/technical-brief
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effectivehealthcare.ahrq.gov/sites/default/files/thompson_eccs2012.pdf
January 01, 2012 - o Combination of disease comprehension
o Awareness of health behavior and treatment guidelines/options … Information (1 of 2)
• Evidential
approaches present
the evidence
of the effects of the disease … If disease
and death
were
viewed
as
inevitable,
participants
speculated
… o Anecdotes can influence a person’s belief about how behavior,
disease, and treatment affects him … o Anecdotes allow people to identify the recipients of treatment and
those experiencing
disease to
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/restless-legs-future_research.pdf
February 01, 2013 - No
eligible studies enrolled individuals with end-stage renal disease, and almost all specifically … • Is RLS associated with cardiovascular disease and other health conditions-in particular
what is the … Is RLS associated with cardiovascular disease and other health conditions—in particular
what is the … C,T
12 Is RLS a risk factor for cardiovascular disease and other health conditions? … • Is RLS a risk factor for cardiovascular disease and other health conditions?
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effectivehealthcare.ahrq.gov/products/hypertension-pulmonary-arterial/research
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-abnormalities-tests_executive.pdf
February 01, 2006 - women would be
newly diagnosed as having breast cancer
and there would be 40,870 deaths due to
this disease … Notes: Sensitivity is the probability that a test is positive in those with the disease. … Specificity is the probability
that a test is negative in those without the disease. … cancer to the probability of a negative test in women without cancer;
based on the risk of having the disease … prior to the test, it is used to calculate the risk of having the disease despite
a negative test result
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/measuring-blood-pressure_executive.pdf
January 01, 2012 - highlighting the contribution
of hypertension directly and indirectly to the development
of numerous diseases … modifiable risk factor for coronary artery
disease, stroke, peripheral vascular disease, congestive … events, terminal illnesses, or
advanced kidney disease. … , diabetes mellitus, and chronic
kidney disease. … End-stage renal disease alone was not significantly different.
-
effectivehealthcare.ahrq.gov/system/files/docs/acute-diverticulitis-topic-nomination.pdf
August 13, 2018 - Epidemiology and pathophysiology of diverticular disease. … Etiology and pathophysiology of diverticular disease. … A systematic review of high-fibre dietary
therapy in diverticular disease. … An approach to complicated diverticular
disease. … AND
Acute acute disease/ or acute.tw,kf.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/stent-clopidogrel-practice_research.pdf
March 01, 2009 - Exclusion criteria included congenital heart disease, moderate/severe
valvular heart disease, prior … All study information was stored in the Duke Databank for Cardiovascular
Disease (DDCD). … , third heart sound, history of cerebrovascular disease, history of peripheral
vascular disease), diagnostic … catheterization findings (left ventricular ejection fraction,
extent of coronary artery disease), … disease, renal disease, liver
disease, metastatic cancer, solid tumor), stent characteristics (average
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-fatigue_research-protocol.pdf
May 01, 2014 - altered
immune and autonomic responses.1,2,7 The variable symptomatology and lack of an
identifiable disease … measurement have challenged
researchers and clinicians in their attempts to better understand the disease … The burden of disease and economic
impact from both medical and societal costs may be in the billions … This topic was nominated by the Office of Disease Prevention (ODP) at the National
Institutes of Health … Myalgic Encephalomyelitis and Postviral Fatigue States: The saga of
Royal Free disease. 1st ed.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/insulin-blood-sugar-2010_research-protocol.pdf
January 01, 2010 - Burden of Diabetes and Its Classification
Diabetes mellitus is defined as a group of metabolic diseases … , cerebrovascular disease, and peripheral arterial disease).
1
The prevalence
of diagnosed diabetes … Cerebrovascular disease
Peripheral arterial disease
Severe hypoglycemia
Quality of life … peripheral arterial disease)
c. … Cerebrovascular
disease
Peripheral arterial
disease
Severe hypoglycemia
Quality of life
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/c-diff-infections_executive.pdf
December 01, 2011 - (a) Does effectiveness vary by disease severity or
strain? … Four studies found use of alcohol gels as
interventions for other infectious diseases, presumably
in … formulation of a probiotic that can effectively target
alterations in the microbiome in CDI and other diseases … Centers for Disease Control and Prevention. … European
Society of Clinical Microbiology and Infectious Diseases
(ESCMID): data review and recommendations
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_research-protocol.pdf
December 06, 2010 - It is an
autoimmune disease that is characterized by inflammation of the synovium (a thin layer
of … The disease tends to affect
the small joints of the hands and feet in a symmetric pattern, but other … Nearly 2 million adults (1%) in the United States have been diagnosed
with the disease.1
Treatment … Available therapies for RA include
corticosteroids, oral disease-modifying antirheumatic drugs (DMARDs … Concurrently, "disease activity" was removed from KQ2 and replaced with
"patient-reported symptoms."
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/pressure-ulcer-prevention_research-protocol.pdf
January 10, 2012 - status; incontinence; or specific medical comorbidities, such as diabetes or peripheral
vascular disease … Published Online: January 10, 2012
6
comorbidities (e.g., diabetes and peripheral vascular disease … [mp=protocol supplementary concept, rare disease
supplementary concept, title, original title, abstract … [mp=protocol supplementary concept, rare disease
supplementary concept, title, original title, abstract … [mp=protocol supplementary concept, rare disease
supplementary concept, title, original title, abstract