-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/acs-depression-research-protocol-amended.pdf
February 15, 2017 - included: (a) clarifying the screening tools to
be considered and how International Classification of Diseases … Global status report on noncommunicable diseases
2014. … Centers for Disease Control and Prevention (CDC). Heart Disease Facts, 2015. … Food and Drug Administration
GI Gastrointestinal
ICD International Classification of Diseases
KQ … Duloxetine Yes Hypertension
Levomilnacipran4 Yes Cerebrovascular disease, Cardiovascular
disease
-
effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1506.pdf
June 01, 2015 - National Digestive Diseases Information
Clearinghouse (NDDIC). Irritable bowel
syndrome. … Bethesda (MD): National
Institute of Diabetes and Digestive and Kidney
Diseases (NIDDK); 2013 Sep … Available:
http://www.mayoclinic.org/diseases-
conditions/irritable-bowel-
syndrome/basics/definition … /irritable-bowel-syndrome/basics/definition/CON-20024578
http://www.mayoclinic.org/diseases-conditions … /irritable-bowel-syndrome/basics/definition/CON-20024578
http://www.mayoclinic.org/diseases-conditions
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_executive.pdf
March 01, 2011 - insulin
secretion by pancreatic beta cells, leading
to chronic hyperglycemia and associated
long-term disease … Long-term complications of diabetes
include microvascular disease, such as
retinopathy and blindness, … neuropathy,
nephropathy, and end-stage kidney disease. … In addition, the death rate from
cardiovascular disease in adults with type
2 diabetes is two to four … Diabetes Care 2006;
29(6):1263-1268.
2 National Institute of Diabetes and Digestive and
Kidney Diseases
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/restless-legs_executive.pdf
November 01, 2012 - Periods
of remission are common, particularly in younger patients
and those with milder disease. … We evaluated RLS symptom
severity and outcome, patient-reported sleep quality,
and disease-specific … Mean
RLS disease duration was 12 years. … No RCTs assessed patients with mild or
moderate disease, and few lasted longer than 6 months. … Severity of disease • Clinical trials include patients with
moderate to very severe disease typically
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/assessing-applicability.ppt
January 01, 2009 - prevalence in study population different than community Prevalence of disease (for diagnostic studies … Finally, evaluate the prevalence of the disease in diagnostic test studies. … If the disease prevalence is markedly different than in the community, then applicability is reduced. … This is especially true in diseases that afflict patients with lower compliance rates such as abusers … In this example, we focus on the age of patients with a disease.
-
effectivehealthcare.ahrq.gov/sites/default/files/assessing-applicability.ppt
January 01, 2009 - prevalence in study population different than community Prevalence of disease (for diagnostic studies … Finally, evaluate the prevalence of the disease in diagnostic test studies. … If the disease prevalence is markedly different than in the community, then applicability is reduced. … This is especially true in diseases that afflict patients with lower compliance rates such as abusers … In this example, we focus on the age of patients with a disease.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/weight-gain-prevention_research-protocol.pdf
January 01, 2020 - Morbidity and Mortality
Obesity is a risk factor for chronic conditions including cardiovascular disease … , diabetes, cardiovascular disease,
cancer, liver disease, or death … Obesity-related clinical
outcomes
• Mortality
• Cancer
• Cardiovascular disease
• Sub-fertility … • Diabetes
• Degenerative joint
disease
• Liver disease
• Quality of life
Adverse effects … Multiple risk factors for cardiovascular disease and diabetes mellitus.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/scarce-resources-protocol.pdf
January 01, 2013 - tiab] OR "emergency planning" OR "emergency preparedness"
OR mass casualt* OR pandemic OR epidemic OR disease … SCIENCE CATEGORIES: ( PUBLIC
ENVIRONMENTAL OCCUPATIONAL HEALTH OR MEDICAL INFORMATICS OR
INFECTIOUS DISEASES … OR "emergency planning" OR "emergency preparedness" OR "mass casualt*" OR
pandemic OR epidemic OR "disease … OR "emergency planning" OR "emergency preparedness" OR "mass casualt*" OR
pandemic OR epidemic OR "disease … outbreak*")):ti,ab,kw OR MeSH descriptor: [Disasters]
explode all trees OR MeSH descriptor: [Disease
-
effectivehealthcare.ahrq.gov/sites/default/files/krishnan_ahrq-mcda-presentation.pdf
August 27, 2012 - Chronic obstructive pulmonary disease
(COPD) as a key health condition.
2. … Analytic hierarchy process to establish
priorities.
2
Chronic Obstructive
Pulmonary Disease … common lung disorder
• 24,000,000 persons
– 3rd leading cause of death
• Deaths rising
• Heart disease … hospital
readmissions
– $49.9 billion / yr
NHLBI Chartbook
3
Chronic Obstructive
Pulmonary Disease
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/arthritis-psoriatric_research-protocol.pdf
December 06, 2010 - The condition is associated with the skin disease
psoriasis, but not all people with psoriasis will … Additionally, PsA may
predate the development of skin disease leading to some diagnostic uncertainty … Available therapies
for PsA include corticosteroids, oral disease-modifying antirheumatic drugs (DMARDs … KQ1: For patients with psoriatic arthritis, do drug therapies differ in their ability to
reduce disease … activity,
and concurrently, "disease activity" was removed from KQ2 and replaced with
"patient reported
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-immunotherapy-2011_research.pdf
January 01, 2011 - if the articles
examined incidence and risk factors for the same disease. … Links between passive smoking and disease:
a best-evidence synthesis. … Interpretation of
genetic association studies in complex
disease. … Source of measure incidence/prevalence of chronic diseases. … ) (define importance of severity specific for the
nature of the disease).
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gerd_executive.pdf
September 01, 2011 - Layout 1
Background
Gastroesophageal reflux disease (GERD) is
one of the most common health conditions … GERD continues to be an important disease in terms of
both cost and public health. … The impact of GERD
treatment may be limited in diseases or symptoms with
complex etiologies, such as … Comparative
Effectiveness of Management Strategies for
Gastroesophageal Reflux Disease. … Management Strategies for
Gastroesophageal Reflux Disease: An Update.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-difficile-future_research.pdf
October 26, 2012 - These include clinically relevant definitions of disease,
disease severity and disease resolution. … Severe underlying disease, acid suppression, and age are indicated as risk factors. … Does effectiveness vary by disease severity or strain?
b. … diverse perspectives, including
methodological/research expertise, clinical experience (from infectious diseases … concomitant antibiotics, role of
carriers, reducing antibiotics by X amount, age,
severity of underlying diseases
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-pancreas_executive.pdf
September 01, 2014 - United States, about 46,000
people received a diagnosis of pancreatic
cancer and 40,000 died of the disease … cancer.1 About
10 percent of patients with pancreatic
cancer have a positive family history of
the disease … As a result,
patients often present with advanced stage
disease when weight loss, jaundice, and
severe … Once pancreatic adenocarcinoma is diagnosed, staging the
disease is critical and is the key determinant … chance of their disease actually
being resectable
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-fatigue_research-protocol.pdf
May 01, 2014 - altered
immune and autonomic responses.1,2,7 The variable symptomatology and lack of an
identifiable disease … measurement have challenged
researchers and clinicians in their attempts to better understand the disease … The burden of disease and economic
impact from both medical and societal costs may be in the billions … This topic was nominated by the Office of Disease Prevention (ODP) at the National
Institutes of Health … Myalgic Encephalomyelitis and Postviral Fatigue States: The saga of
Royal Free disease. 1st ed.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/type-2-diabetes-medications-update_research-protocol.pdf
April 06, 2010 - and exercise, glycemic control using a variety of medications, and lowering
co-morbid cardiovascular disease … improved glycemic control
reduces microvascular complications,1, 5-8 but the impact on cardiovascular disease … and events, peripheral
vascular disease and amputations, and stroke) and microvascular complications … National Center for Chronic Disease Prevention and Health Promotion. … National Center for Chronic Disease Prevention and Health Promotion.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-diff-infections_research-protocol.pdf
May 24, 2010 - Background and Objectives for the Systematic Review
Clostridium difficile associated disease (CDAD … Does effectiveness vary by disease severity or strain?
b. … United States Centers for disease Control and Prevention. … Emerging therapies in the treatment of Clostridium
difficile-associated disease. … Current and future treatment modalities for Clostridium difficile-associated disease.
-
effectivehealthcare.ahrq.gov/sites/default/files/11_pepticulcer_potential_high_impact_june_2012.pdf
January 01, 2012 - (The therapy
has also recently been identified as being explored for other autoimmune diseases such … The rationale for this treatment
stems from the observation that inflammatory bowel diseases are rare … The rationale for this treatment stems from
the observation that inflammatory bowel diseases are rare … and other inflammatory bowel diseases.
8
The manufacturer does not appear to intend to seek FDA … Bethesda
(MD): National Digestive Diseases Information
Clearinghouse; [accessed 2011 Jun 6]. [4 p
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/pbi-protocol.pdf
August 09, 2021 - : new primary tumors have
more favorable outcomes than true local disease recurrences. … frequency study" or
"disease frequency analysis" or "disease frequency survey" or crossover or "cross-over … frequency study" or "disease frequency analysis" or "disease frequency
survey" or crossover or "cross-over … frequency study” or
26
“disease frequency analysis” or “disease frequency survey” or crossover … frequency study" or "disease frequency analysis" or "disease frequency
survey" or crossover or "cross-over
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_10-user-guide-to-ocer_130129.pdf
January 01, 2011 - Disease risk scores estimate the probability or rate of disease occurrence
as a function of the covariates … become more common in
recent years include using summary variables,
such as propensity scores and disease … Disease Risk Scores
The disease risk score (DRS) is an alternative
to the propensity score.36-37 Like … It is useful for summarizing
disease risk and assessing effect modification
by disease risk. … Use of disease risk scores
in pharmacoepidemiologic studies.