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Showing results for "difficult".

421. Ch 10-User-Guide-To-Ocer 130129 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/ch_10-user-guide-to-ocer_130129.pdf
     January 01, 2011 - However, difficult issues arise when both treatment and confounding variables vary over time. … However, such a variable may be difficult or impossible to identify in some settings.

422. Prostate-Cancer-Risk-Assessment-Genes Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-risk-assessment-genes_executive.pdf
     July 01, 2012 - history, the risk factors associated with prostate cancer are unclear,6 making primary prevention difficult … prostate cancer is highly variable.13 In a large proportion of men, the disease is indolent, and it is difficult

423. #14 SUBSTANCE ABUSE (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1406.pdf
     January 01, 2020 - identify and respond to an opioid overdose such as heroin, may find the injection delivery method difficult … improve patient health outcomes, but stated that replicating the model in other communities may be difficult … results suggest that the program is effectively addressing an unmet need in North Carolina, it may be difficult

424. Comparative Effectiveness Review Disposition of Comments Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-chronic-conditions-interventions_disposition-comments.pdf
     August 13, 2012 - to categorize substance abuse (as a mental health condition or a chronic medical condition) is a difficult … It would be difficult to boil the messages down to the 1 page that might reach users, but if one could … Peer #3 Discussion/ Conclusion At the end it was difficult to discern how the review could potentially … chance for clarity has been overwhelmed by the length and depth of this report, which also make it difficult … The conclusions may be difficult to translate into policy because of the funding considerations.

425. Disposition of Comments Report for Core Needle and Open Surgical Biopsy for Diagnosis of Breast Lesions: An Update to the 2009 Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_disposition-comments.pdf
     September 10, 2014 - with second look ultrasound), are then biopsied by MRI; clearly, these are a very different and more difficult … Again, this comprises a more difficult group of lesions than lesions typically biopsied using ultrasound … At present, it is difficult to relate verbal description of dots and dashes to lines in the figure. … Understandably it may be difficult to discern what is palpable and what is not palpable particularly … On page 20, in the "Contextualizing the results of test performance meta-analysis" section, I had a difficult

426. PEPTIC ULCER #11 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1312.pdf
     December 01, 2013 - by prolonged occlusion of the LES and reduced peristaltic activity, making the swallowing of food difficult … might be less effective than laparoscopic surgery over the long term and revisional surgery might be difficult … Achalasia is characterized by prolonged occlusion of the LES and reduced peristaltic activity, making it difficult … it may not be as effective long term as laparoscopic surgery and that revisional surgery might be difficult … Health disparities: Two experts representing clinical perspectives stated that PN is difficult to administer

427. Disposition of Comments for Technical Brief 27 Patient Safety (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ambulatory-safety_disposition-comments.pdf
     October 19, 2016 - Good description of why outpatient settings are more difficult to track. … , that is because it is the state of the published literature Peer Reviewer #1 General It can be difficult … In these situations, communication between providers may be difficult and inefficient making care prone … readers memory KI Reviewer #1 Findings Findings (page 15) - Figure 1 matrix- I found this very difficult … It is difficult to be more specific about recommendations where there is a lack of evidence.

428. Disposition of Comments for Epoetin and Darbepoetin for Managing Anemia in Patients Undergoing Cancer Treatment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-anemia-update_disposition-comments.pdf
     April 25, 2013 - This is a serious limitation related to the literature about ESAs - one that makes it particularly difficult … specific examples of the duplicate / triplicate references are indicated in the comments below but it is difficult … A multivariate analysis has potential to be difficult to interpret. … Because readers may find the notion of varying underlying risk difficult, we chose to not to use that … Commentator & Affiliation Section Comment Response literature, and it makes it particularly difficult

429. Dementia-Agitation-Aggression Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/dementia-agitation-aggression_executive.pdf
     March 01, 2016 - behavior change, reduction in antipsychotic use Adverse Effects of Intervention(s) Increase in other difficult … Staff training is even more difficult when the staffing is unstable or staff feel great pressure to … The more that interventions require clinical judgment, the more difficult they are to implement, especially … the applicability of results of trials conducted in nursing homes and assisted living facilities is difficult … Nonetheless, this line of research will continue to be difficult.

430. Comparative Effectiveness Research Review Disposition of Comments Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/disabilities-quality-improvement-outcomes_disposition-comments.pdf
     October 15, 2012 - Therefore it is a little difficult to say whether the key questions have been answered or the conclusions … As stated in the report, it is very difficult to write search algorithms that are specific to the topic … Reviewer #7 Executive Summary The Executive Summary is far too detailed, too long, and very difficult … However, from our experience in the systematic review field, when literature is as difficult to locate

431. Disposition of Comments for CER 172 Clostridium Difficile Diagnosis Prevention Treatment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/c-difficile-update_disposition-comments.pdf
     March 29, 2016 - A consensus reference standard would be problematically heterogeneous and make analysis difficult … This is a difficult area to discuss and perhaps the authors chose not to discuss this in detail given … It is difficult to create a table that fully incorporates all pertinent and important points that … Peer Reviewer #6 Figures The forrest plots and figures are small and difficult to see.

432. Community-Based Participatory Research: Lessons for Stakeholder Engagement in Patient-Centered Outcomes Research (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/lessons-transcript.pdf
     January 06, 2017 - they often need stakeholder input in projects with short timelines or immediate start dates and it’s difficult … PCOR is operating on a three year agenda and it will be very difficult for them to adhere to CBPR in … having a neutral facilitatory so many times if it’s the researcher that’s running the meeting it’s very difficult … We need to answer difficult questions like who’s responsible for this.

433. Antidepressant Treatment of Depression During Pregnancy and the Postpartum Period (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-pregnancy-postpartum_executive.pdf
     July 01, 2014 - Indirect comparisons can be difficult to interpret for several reasons; in the case of comparison with … Known Putting these findings into the context of prior comparative effectiveness evidence reviews was difficult … The clinical relevance of the nonpharmacological treatment modalities was difficult to assess because … Likewise, the clinical relevance of the pharmacological treatment regimens was difficult to assess

434. Disposition of Comments Report for Treatment for Hepatitis C Virus Infection in Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_disposition-comments.pdf
     November 27, 2012 - In general, when there is only a single trial, it is difficult to draw a conclusion regarding the strength … and free of bias but the review limits itself to treatment-naive individuals and does not consider "difficult-to-treat … This was a difficult task and is done very well. … fact that these recommendations apply only to treatment-naive individuals and does not apply to "difficult-to-treat

435. Weight-Gain-Prevention Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/weight-gain-prevention_executive.pdf
     January 01, 2020 - Differences in opinion were resolved through consensus adjudication and, for difficult cases, during … the robust evidence that obesity is associated with poor health outcomes,5-12 is costly,3 and is difficult … Behavior change is difficult for individuals whose goal is to prevent weight gain, just as behavior … change is difficult for those attempting to lose weight.

436. DRAFT - Prehospital Airway Management: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/prehospital-airway-management-draft-report.pdf
     November 01, 2020 - Bias, confounding, and incomplete data are difficult to avoid, given the nature of airway management … This is made more difficult by the lack of a definitive gold standard in prehospital care and the wide … Since the SGA is placed above the glottis, it may also be more difficult to hyperventilate with the … This is not surprising as prospective studies and trials are more difficult, more costly, and subject … For example, the race of patients is rarely reported in these studies, making it difficult to determine

437. DRAFT - Prehospital Airway Management: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/prehospital-airway-management-draft-report.pdf
     November 01, 2020 - Bias, confounding, and incomplete data are difficult to avoid, given the nature of airway management … This is made more difficult by the lack of a definitive gold standard in prehospital care and the wide … Since the SGA is placed above the glottis, it may also be more difficult to hyperventilate with the … This is not surprising as prospective studies and trials are more difficult, more costly, and subject … For example, the race of patients is rarely reported in these studies, making it difficult to determine

438. Methods Guide for Comparative Effectiveness Reviews_Inclusion of Nonrandomized Studies of Interventions in Systematic Reviews of Intervention Effectiveness: An Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/methods-guide-inclusion-nonrandomized-studies.pdf
     September 01, 2022 - key to the development of systematic reviews and describes recommended approaches for addressing difficult … inference • Restricted to one outcome only • Cannot measure incidence/risk • Sometimes difficult … Longitudinal Prospective or retrospective, or mixed • Ease of participant enrollment • Difficult … Early in the evolution of evidence on a topic, when limited evidence from RCTs may be available, it is difficult … Two challenges with the IV approach worth noting are (1) it is often difficult to find an appropriate

439. Methods Guide for Comparative Effectiveness Reviews_Inclusion of Nonrandomized Studies of Interventions in Systematic Reviews of Intervention Effectiveness: An Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/methods-guide-inclusion-nonrandomized-studies.pdf
     September 01, 2022 - key to the development of systematic reviews and describes recommended approaches for addressing difficult … inference • Restricted to one outcome only • Cannot measure incidence/risk • Sometimes difficult … Longitudinal Prospective or retrospective, or mixed • Ease of participant enrollment • Difficult … Early in the evolution of evidence on a topic, when limited evidence from RCTs may be available, it is difficult … Two challenges with the IV approach worth noting are (1) it is often difficult to find an appropriate

440. Management of Infantile Hemangioma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/infantile-hemangioma_clinician.pdf
     June 01, 2016 - Studies used multiple and variable outcome measures to assess resolution of lesions, which makes it difficult