-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pressure-ulcer-treatment_executive.pdf
May 01, 2013 - The study may be missing information, making it difficult
to assess limitations and potential problems … reported, integrating those data to answer questions about
treatment combinations and timing was difficult … outcomes are influenced by local practices, staffing,
and other features of the environment, it is difficult … applicability discussed above, as well as
the limitations of the evidence base discussed below, make
it difficult … In addition, measurement in person
or from tracings or photographs can be difficult, especially
when
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-201-indoor-allergen-asthma-disposition-comments.pdf
February 15, 2018 - However, the form is very dry and quite
difficult to follow. … home (and would likely be a problem in
a clinical setting, given that a challenge would likely be
difficult … The manuscript
notes (roughly) that this makes it difficult to resolve
which factor mattered most. … However, the
form is very dry and quite difficult to follow. … Again, the inclusion of 2 unrelated
treatment approaches makes this document a bit more
difficult to
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_disposition-comments.pdf
September 29, 2014 - In some cases, the article did
not report important information, making it difficult to assess its methods … for the authors to report the
proportion of studies for which methods or potential limitations were difficult … For another issue, even with the information provided
in Appendix E it remains difficult to appreciate … it
seems incumbent on the authors to indicate the proportion of included studies for
which it was difficult … Summary of evidence, difficult to read. Suggest dividing into one
table for each key question.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_executive.pdf
September 19, 2014 - In some cases, the article did
not report important information, making it difficult to
assess its … versus sustained-release opioids
reported inconsistent results on outcomes related to pain
and are difficult … Although uncontrolled studies
of patients prescribed opioids are available,8 findings
are difficult … clinically significant pain relief.8 However, results of the
studies included in this review are difficult … Long-term randomized trials of opioid therapy are difficult
to implement due to attrition, challenges
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/research-gaps_research.pdf
February 01, 2013 - Research gaps which are difficult to characterize into the PICOS framework should be abstracted
in free … These are often gaps for which it is
difficult to identify a clear intervention or comparison of interest … Research gaps which are difficult to characterize into the PICOS framework should be abstracted
in free … These are often gaps for which it is
difficult to identify a clear intervention or comparison of interest … At the FRN point it is almost too late; too difficult to use.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/wheelchair-service_disposition-comments.pdf
January 01, 2012 - Unfortunately, it is difficult to
fund the appropriate team of professionals given the current
reimbursement … Yes the references are there, but the in the body
of the report this information is difficult to tease … If you are trying to show that
wheeled mobility use in the US is growing it is difficult to
gather … "this may be, in part,
because... need to say also because equipment trial may
be difficult due to … It is difficult to fully evaluate the
current best clinical practice for assistive device
assessment
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_disposition-comments.pdf
March 01, 2012 - This entire section is difficult to follow. Can you please clarify. … inclusion and exclusion
criteria used by the studies relevant to the topic
make it extraordinarily difficult … It
may be difficult to justify a switching study (which will be very
difficult to implement) before … It is difficult to address this comment without
additional specificity. … Because that
pathology is different between patients who present with similar
seizures, it is difficult
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cesarean-birth-2010_disposition-comments.pdf
January 01, 2010 - In a
growing field there will always be new studies published,
and it is difficult but necessary to … It is true that unclear reporting makes the assessment of
risk of bias particularly difficult; however … October 22, 2012
16
Reviewer Section Comment Response
Peer
Reviewer #4
Results It was somewhat difficult … Clearly
this is a difficult analysis due to the wide variety of
components of the studies. … For the reviewer to pick those out as they
meander through 100 pages may be difficult.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-treatment-future_research.pdf
February 01, 2013 - It would be difficult to design clinical trials to compare the influence of these different
clinical … within the context of a trial,
particularly if blinding must be maintained, is both expensive and difficult … The
main challenge here is accessibility to the appropriate data, which may be difficult, especially … Paper records are difficult to abstract because of issues
relating to legibility, consistency in diagnostic … number of respects, such as income and employment history, that may be
relevant, but which may be difficult
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-antigen-3-gene_research.pdf
April 01, 2013 - It would be difficult to perform the randomized clinical trial that would be required to
establish the … The panel recognized that this research need might be difficult to
address, but concluded that test … Recruitment of
subjects should not be difficult although
future studies should learn from the
comparative … Recruitment of subjects should
not be difficult although future studies should
learn from the comparative … These models are difficult
to compare across studies and do not allow for simple inclusion of new variables
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/patient-navigation-model-lung-cancer-rapid.pdf
December 01, 2018 - medical field, interact with patients and family, learn strategies to
overcome barriers to care and difficult … It was often
difficult to determine what patient navigators actually did, beyond the general definition … This lack of clarity makes it difficult to interpret the effectiveness
results of the studies and difficult
-
effectivehealthcare.ahrq.gov/sites/default/files/selection-of-data-sources-chapter-8.pptx
January 01, 2013 - data streams are often specialized, and, without linkage to other patient characteristics, it can be difficult … However, pooled analyses require close coordination and can be very difficult to complete due to differences
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-principles_methods.pdf
August 01, 2009 - development of Comparative
Effectiveness Reviews and describes recommended approaches for addressing difficult … The chapters
in this guide describe recommended approaches for addressing difficult, frequently encountered
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/distributed-network-blueprint_research.pdf
June 01, 2010 - multiple health data networks, raising the likelihood that independent, single-
purpose networks will be difficult … standardization of definitions, analytic approaches, and data quality that will otherwise be
extremely difficult
-
effectivehealthcare.ahrq.gov/products/fatty-acids-cardiovascular-disease/clinician
July 25, 2017 - differences exist between RCTs and observational studies, making comparisons across the two study designs difficult
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/fatty-acids-cardiovascular-disease_clinician.pdf
July 01, 2017 - differences exist between RCTs and observational
studies, making comparisons across the two study designs
difficult
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-232-breathlessness-cancer-comments.pdf
November 19, 2020 - Reviewer #2 (TEP) Clarity and
Usability
Difficult to understand how the authors interpreted the
existing … clarify the methodology for
making conclusions – for this specific example, clinical
meaningfulness was difficult … Methodologically, I understand why the data is
presented in the current format, but I found it difficult … Regardless, it was difficult to conclude much about side
effects given reporting issues.
-
effectivehealthcare.ahrq.gov/products/inguinal-hernia/research-protocol
April 11, 2011 - Balancing these factors is a difficult yet critical process in an effort to make the best possible medical … Surgical complications of combined operations make it difficult to isolate aspects of the hernia repair … patients in the studies (whereas tau is a more direct measure of heterogeneity), 36 but tau is more difficult
-
effectivehealthcare.ahrq.gov/products/liver-cancer-therapy/research-protocol
March 20, 2012 - First, it is difficult to classify interventions based on curative or palliative intent of the treatment … classification systems and the inability to translate disease stage from one system to another made it difficult … chemotherapy and other treatment specifics that may or may not be reported that render comparisons difficult
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/liver-cancer-therapy_research-protocol.pdf
November 28, 2012 - First, it is difficult to classify interventions based on curative or
palliative intent of the treatment … classification systems and the inability to translate
disease stage from one system to another made it difficult … chemotherapy and other treatment specifics that may or may not be reported
that render comparisons difficult