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Total Results: 1,287 records

Showing results for "difficult".

281. Acs-Pci-Adjunctive-Devices Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/acs-pci-adjunctive-devices_surveillance.pdf
     April 01, 2013 - It was difficult to assess the impact of these devices on final health outcomes and intermediate outcomes … It was difficult to assess the impact of these devices on final health outcomes and intermediate outcomes

282. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/rotator-cuff-tear_executive.pdf
     July 01, 2010 - result in an earlier return to work, and decreased costs; therefore, patients and clinicians face the difficult … arthroscopic approaches is also a priority, as arthroscopic procedures are more costly and technically difficult

283. new disposition of comments insulin analogues -- jda revs.xls (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/insulin-analogues-disposition-081229.pdf
     September 01, 2008 - It can be more difficult to recruit certain groups, and more costly to do the studies, and more risky … Page 4: Figure 3 is very difficult to understand. … We find it difficult to compare insulin detemir dose in a trial that compared detemir with glargine … Insulin dose: It is difficult to interpret treatment differences in comparator trials in which the total … Overall presentation and relevancy In general, I found this report very difficult to read.

284. Disposition of Comments for Treatments for Fibromyalgia in Adult Subgroups (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/fibromyalgia_disposition-comments.pdf
     January 26, 2015 - : Methods Page ES-4: Quality (Risk of Bias) Assessment of Individual Studies: The section was difficult … Is there data suggesting that FM is more difficult to treat in obese patients or in older patients? … the scope of the report, but bringing in information about the most common comorbidities or most difficult … Discussion/ Conclusions I think the findings are generally sound but the paucity of evidence makes it difficult … The clinical meaning of the report is somewhat difficult to assess - mostly because the data they reviewed

285. Disposition of Comments CER 185 Tympanostomy Tubes in Children With Otitis Media (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/tympanostomy-tubes-disposition.pdf
     May 05, 2017 - inconsistencies in the approaches used within and between the key questions which make it sometimes difficult … We agree that the reliability and validity of hearing evaluations in children is important, albeit difficult … ability to show improvements in these areas on groups of children without any baseline problems is difficult … I prefer RR rather than OR, since OR is more difficult to interpret and tend to overestimate the … Reading the document in this (on- line) format makes it somewhat difficult to judge.

286. Disposition of Comments CER 185 Tympanostomy Tubes in Children With Otitis Media (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/tympanostomy-tubes-disposition.pdf
     May 05, 2017 - inconsistencies in the approaches used within and between the key questions which make it sometimes difficult … We agree that the reliability and validity of hearing evaluations in children is important, albeit difficult … ability to show improvements in these areas on groups of children without any baseline problems is difficult … I prefer RR rather than OR, since OR is more difficult to interpret and tend to overestimate the … Reading the document in this (on- line) format makes it somewhat difficult to judge.

287. Disposition of Comments Report for Assessment and Management of Chronic Cough (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-cough_disposition-comments.pdf
     January 07, 2013 - Many have been inadequately validated and so it’s difficult to really comment on their performance … Peer Reviewer #3 General Some of the nuances of the differences between these studies that make them difficult … I wholly agree with them that it is difficult to establish the accuracy of particularly the electronic … I sympathise with the reviewers because, through no fault of their own, it is extremely difficult to … This is however a complex and difficult task and must be extremely challenging for those without specific

288. Screening and Diagnosing Gestational Diabetes Mellitus Disposition of Comments Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/gestational-diabetes-screening-diagnosis_disposition-comments.pdf
     January 01, 2020 - Section Comment Response Peer Reviewer #1 General This is a well written, comprehensive review of a difficult … The authors are to be congratulated for admirably taking on this difficult subject. … In the end, as stated above, the report will provide valuable context for what will surely be a difficult … The conclusions, due to the limitations of the available evidence, will be difficult to use to create … The absence of references in many parts of the manuscript (including tables and appendices) makes it difficult

289. PEPTIC ULCER #11 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/11_pepticulcer_potential_high_impact_june_2012.pdf
     January 01, 2012 - the lower esophageal sphincter (LES) and reduced peristaltic activity, making swallowing of food difficult … effective as laparoscopic surgery in the long term, some speculate, and revisional surgery might be difficult … the lower esophageal sphincter (LES) and reduced peristaltic activity, making swallowing of food difficult … Revisional surgery might be difficult and involve extensive procedures such as esophagectomy. 23 … Two experts representing a clinical perspective stated that PN is difficult to administer to patients

290. Hemorrhage-Postpartum Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hemorrhage-postpartum_executive.pdf
     April 01, 2015 - Harms reporting was limited to 50 studies and was difficult to synthesize because diverse adverse events … Overall, it was difficult to ascertain confidently the complete trajectory of care of women in many … Outcomes other than control of bleeding can be difficult to assess. … In some cases, it can be difficult to assess if harms are due to PPH or management interventions and … Diagnosis of PPH is subjective, which makes it difficult to compare the severity of PPH and determine

291. Disposition of Comments Report for Primary Care Management of Abnormal Uterine Bleeding (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/abnormal-uterine-bleeding_disposition-comments.pdf
     March 21, 2013 - Peer reviewer #4 Executive Summary Tables B and C Tables B and C are difficult to interpret without … Thus comparisons across studies are difficult. … Response Peer reviewer #4 Results Identification of studies to answer Key Question 2 was especially difficult … It may be reasonable to state (somewhere) that it is frequently difficult to evaluate the impact of … Furthermore, the questions related to nomenclature are difficult to address within a systematic evidence

292. Disposition of Comments Report for Comparison of Characteristics of Nursing Homes and Other Residential Long-Term Care Settings for People With Dementia (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/dementia-nursing-home-characteristics_disposition-comments.pdf
     October 23, 2012 - Sometimes an adequate sample size is difficult to achieve because an outcome under study (such as aggressive … We recognize that within this population that this may be difficult to achieve and we have added this … This was nominated by a layperson, but is dense and difficult to read for me. … What seems to be two objectives are actually one, which may have made the logic difficult to understand … caregiver's own personality characteristics, life experience and current life situation that would be very difficult

293. Prehospital Airway Management: A Systematic Review | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/prehospital-airway-management/protocol
     February 19, 2020 - This is made more difficult by the lack of a definitive gold standard in prehospital care and by the … The study may be missing information, making it difficult to assess limitations and potential problems

294. Disposition of Comments: Management of Colonic Diverticulitis (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/diverticulitis-comments.pdf
     October 12, 2020 - As written, it’s difficult for the reader to understand the manuscripts guidance on this topic. … ES-1, the following sentence is difficult to follow: "There is low SoE that antibiotics for patients

295. Evidence-based Practice Center Systematic Review Protocol: Prehospital Airway Management (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/prehospital-airway-management-protocol.pdf
     December 20, 2019 - This is made more difficult by the lack of a definitive gold standard in prehospital care and by the … The study may be missing information, making it difficult to assess limitations and potential problems

296. Comparative Effectiveness and Safety of Insulin Delivery and Glucose Monitoring Methods for Diabetes Mellitus | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/insulin-blood-sugar-2010/research-protocol
     June 02, 2011 - Because of the pharmacokinetics of these older insulins, tight control was difficult to achieve and often … Because insulin regimens may change over time, it may be difficult to determine if the current delivery … Patients with maturity onset diabetes of the young will also be excluded, as the diagnosis is difficult … The study may have been missing information, making it difficult to assess limitations and potential

297. Comparative Effectiveness Research Review Disposition of Comments Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-abnormalities-tests-update_disposition-comments.pdf
     February 13, 2012 - Executive Summary PPV2 and 3 would be better metrics than sensitivity since false negatives are difficult … average risk patients, application of this data to findings on routine screening in normal risk women is difficult … In addition, little information was reported about different patient subgroups, making it difficult … research section is also clear, although if the ideal RCT design is “admittedly < . . . > logistically difficult

298. Disposition of Comments Report for Pressure Ulcer Risk Assessment and Prevention (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/pressure-ulcer-prevention_disposition-comments.pdf
     May 08, 2013 - Unfortunately it is difficult to obtain an accurate estimates of pressure ulcer incidence in the U.S … diagnostic accuracy blinded caregivers to the results of risk assessment scores (blinding might be difficult … As indicated by the authors, specificity is difficult to interpret in these studies given that it reflects … many of the trials of support surfaces evaluated specific brand name products and that it may be difficult … Samples of adequate size are often difficult to obtain and follow for prolonged periods.

299. Future Research Needs for Angiotensin-Converting Enzyme Inhibitors (ACEIs), Angiotensin II Receptor Antagonists (ARBs), or Direct Renin Inhibitors (DRIs) for Treating Hypertension (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-future_research.pdf
     March 01, 2012 - inhibitor or ARB) Due to low numbers of deaths or major cardiovascular events reported, it was difficult … within the context of a trial, particularly if blinding must be maintained, is both expensive and difficult … The main challenge here is accessibility to the appropriate data, which may be difficult, especially … Paper records are difficult to abstract because of issues relating to legibility, consistency in diagnostic … number of respects, such as income and employment history, that may be relevant, but which may be difficult

300. Antinuclear Antibody, Rheumatoid Factor, and Cyclic-Citrullinated Peptide Testing for the Evaluation of Musculoskeletal Complaints in Pediatric Populations | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/musculoskeletal-complaints-tests-children/research-protocol
     September 29, 2010 - MSK pain can be difficult for children to characterize and can cause children and parents great anxiety … nature of the signs and symptoms of many rheumatic diseases and noninflammatory pain syndromes make it difficult