-
effectivehealthcare.ahrq.gov/sites/default/files/kravitz_eccs2012.pdf
January 01, 2012 - the Accuracy and Balance of Media Reports
on
Prescription Drugs
• Journalists
are
now in a difficult
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/blood-clots-hip-knee-surgery_executive.pdf
March 01, 2012 - Comparing LMWH agents with DTIs is
difficult because the occurrence of DVT was greater, but
the occurrence … It is difficult to discern the comparative balance of
benefits and harms for oral antiplatelet therapy … It is difficult
to discriminate between DVT being causative for, or
colinear with, the occurrence of … direct comparative trials
are needed between classes of drugs, but funding these
trials could be difficult … The large number of
mechanical prophylactic devices available also makes
it difficult to conduct a
-
effectivehealthcare.ahrq.gov/sites/default/files/study-design-considerations-chapter-2.pptx
January 01, 2013 - of ad hoc studies when compared with a cohort study
Can assess multiple exposures
Limitations:
Is difficult … Limitations
Case-control studies can be difficult to conceptualize. … Both confounding by indication and confounding by frailty may be strongest and most difficult to adjust
-
effectivehealthcare.ahrq.gov/products/cancer-end-of-life-measures-framework/research
May 13, 2010 - indicators approved by the NQF defined the denominator retrospectively from the time of death, making it difficult … oncology, hospice) have not been well-coordinated, making combining or comparing results across settings difficult … diseases and many patients have multiple comorbidities at the end-of-life, isolating cancer issues is difficult
-
effectivehealthcare.ahrq.gov/products/cancer-quality-indicator-framework/research
May 13, 2010 - indicators approved by the NQF defined the denominator retrospectively from the time of death, making it difficult … oncology, hospice) have not been well-coordinated, making combining or comparing results across settings difficult … diseases and many patients have multiple comorbidities at the end-of-life, isolating cancer issues is difficult
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_3-user-guide-to-ocer_130129.pdf
September 21, 2012 - race or ethnicity,
these characteristics may represent proxies for
genetic differences that are more difficult … A major problem with these analyses is that
it is extremely difficult to obtain the sampling
properties … essential
Characterization of
sampling error of the
statistical estimator
Easy to achieve Possible Difficult
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/plasma-cell-dyscrasias-sflc-assay_disposition-comments.pdf
August 23, 2012 - this is an
entity that has no clinical symptoms and is defined only by
an abnormal rFLC, it becomes difficult … LC-MGUS
and agree that if the FLC ratio is the only abnormal test that
signals the condition, it is difficult … Affiliation
Section Comment Response
Peer Reviewer
#5
Results Amyloidosis is a very rare and often difficult
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/medication-adherence-interventions_disposition-comments.pdf
September 11, 2012 - For readers interested in a general overview of
adherence, this is very difficult sledding. … For example, Table 6, p. 29 of
the report is very difficult to read and interpret because of its formatting … Perhaps the range of topics covered by the KQs and the heterogeneity of
the literature make it difficult … All the required elements of this review make it
difficult to substantially reduce the size of the … and the portions reviewed of the body of
the review, are well written and concise, the abstract is difficult
-
effectivehealthcare.ahrq.gov/products/dietary-supplements/research-protocol
December 21, 2010 - Drug-Dietary Supplement Interactions: In the clinical setting, drug-supplement interactions are more difficult … The variability in dietary supplement constituents, quality, and dosage makes it difficult to compare … evidence of interactions between dietary supplements and cardiovascular drugs are small in size and difficult … The study may be missing information, making it difficult to assess limitations and potential problems … impact of studies published in languages other than English in a meta-analysis may be minimal, it is difficult
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/undescended-testicle_disposition-comments.pdf
December 11, 2012 - primary exception to the recommendation against US is in the obese
patient, in whom an inguinal UDT is difficult … boys can be
challenging and the distinction between retractile and truly undescended
testes can be difficult … While it is difficult to separate such cases in most
literature reports on cryptorchidism/orchiopexy … While long-term studies like the ones
proposed in the future research section are
difficult, they are … The older literature is difficult to
compare with the more recent literature, as surgical standard of
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-emergency_disposition-comments.pdf
November 27, 2012 - Having
just reviewed this same topic myself, I am aware of how difficult it is to
gather good data … I understand that it is somewhat
difficult to classify as it is a weak neuroleptic, an antiemetic, and … Peer Reviewer
#8
Methods Migraine headache outcomes are difficult to measure but the report
provides … and
neuroleptics there is no discussion of dose equivalence, making
interpretation of comparators difficult … Results Page 50: In trying to find reference #101, it became apparent that this
very long document is difficult
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/nppv-respiratory-failure_disposition-comments.pdf
July 01, 2012 - Seems almost as important to me as the
difficult patient sub group types. … Peer Reviewer 5 Executive
Summary
Page 12 [ES-4]: Fig ES 1 - is a poor reproduction and difficult … Peer Reviewer 5 Introduction Figure 1, page 37 [6] – difficult to read, please provide a more clear … This is a difficult area to characterize in review of
research investigations since appropriate trained … Peer Reviewer 4 Methods 10) In the quality rating section, comparability of groups at baseline is
difficult
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-knee-update-disposition.pdf
May 04, 2017 - after 3 dropouts) in
the resistance training arm, and 9 (after
4 dropouts) in the control arm, it is
difficult … Results Similarly, not displaying the number of
participants in study arms makes the
forest plots difficult … It's very difficult to read. … Appendix I includes it, but the table has
considerable text making it a little difficult
to identify … It is difficult to
recommend practice or policy changes
based on such limited information.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/systematic-review-integration_white-paper.pdf
June 01, 2014 - Although EPC members felt that it was often difficult to gain efficiency using existing
reviews, they … Food and Drug Administration trials, representing work from systematic reviewers that would be
very difficult … It
can often be difficult to find reviews that match on all elements of question. … of bias assessments, an
overarching theme from the discussion with EPC members was that it may be difficult … Specifically, it can be difficult to highlight primary studies or isolate results from individual
studies
-
effectivehealthcare.ahrq.gov/sites/default/files/11_peptic_ulcer_potential_high_impact_2012-12-111.pdf
January 01, 2012 - prolonged occlusion of the lower
esophageal sphincter (LES) and reduced peristaltic activity, making it difficult … might not be as effective as laparoscopic surgery in the long term, and
revisional surgery might be difficult … However, if TSO shows
efficacy in that difficult-to-treat patient population, it could greatly add … it may not be as effective long term as laparoscopic surgery and that revisional
surgery might be difficult … Two experts representing a clinical perspective stated that PN is difficult to administer to
patients
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-health-children_disposition-comments.pdf
December 19, 2016 - Peer Reviewer 1 Discussion/
Conclusion
Part of the reason is that there is so little research it is
difficult … The authors should be clear that
this was confusing and difficult to do.
So noted. … Peer Reviewer 7 General The result is a review of studies that are so disparate
that it is difficult … set
of papers and the reliance on qualitative analysis
creates a very complex report that I found difficult … TEP 6 General Splitting the descriptions across the key questions
makes it quite difficult to get a
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/long-term-care-adults_disposition-comments.pdf
November 07, 2012 - across states have been inconsistent
because assessing the cost and effectiveness of HCBS has been
difficult … This makes the comparison with home care programs
even more difficult. … Reviewer #1 Results The large number of tables in the text of the report were difficult to
deal with … complexity of the information and the
presentation method of relying primarily on tables makes it difficult … It is
difficult to estimate the impact that such a report will have for a
number of reasons.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/patient-centered-medical-home_disposition-comments.pdf
July 03, 2012 - This discrepancy is difficult to explain. … Table 22: Table 22 was easier to understand after having
read the previous sections; however, it was difficult … However,
measuring the impact of interventions on these
outcomes is difficult because of the long period … for
Medical Home
Implementation
Discussion The conclusions made in this report may make it more difficult … influenced, resulting in an environment in which sustaining the
medical home will become increasingly difficult
-
effectivehealthcare.ahrq.gov/sites/default/files/osteoarthritis-knee-update-disposition.pdf
May 04, 2017 - after 3 dropouts) in
the resistance training arm, and 9 (after
4 dropouts) in the control arm, it is
difficult … Results Similarly, not displaying the number of
participants in study arms makes the
forest plots difficult … It's very difficult to read. … Appendix I includes it, but the table has
considerable text making it a little difficult
to identify … It is difficult to
recommend practice or policy changes
based on such limited information.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-knee-update-disposition-archived.pdf
May 04, 2017 - after 3 dropouts) in
the resistance training arm, and 9 (after
4 dropouts) in the control arm, it is
difficult … Results Similarly, not displaying the number of
participants in study arms makes the
forest plots difficult … It's very difficult to read. … Appendix I includes it, but the table has
considerable text making it a little difficult
to identify … It is difficult to
recommend practice or policy changes
based on such limited information.