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Total Results: 1,316 records

Showing results for "difficult".

381. Therapies for Clinically Localized Prostate Cancer (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-update_clinician.pdf
     January 01, 2016 - patient population for RP, radiation therapy, hormonal therapy, WW, AS, or one of the other options is difficult

382. Layout 1 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-2007_executive.pdf
     January 01, 2007 - cohort studies, and relatively small sample sizes for ARBs, the precise magnitude of this effect is difficult

383. Layout 1 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/head-neck-cancer_executive.pdf
     May 01, 2010 - There is insufficient detail about methods used in the yet-to-be published randomized trial, so it is difficult

384. THIS IS OUR TEACHER! (ppt file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/communicating_risk_media_wilkes.ppt
     April 01, 2006 - to recognize the limitations of language Human beings are not good at statistical reasoning Very difficult

385. Pressure-Ulcer-Treatment Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/pressure-ulcer-treatment_executive.pdf
     May 01, 2013 - The study may be missing information, making it difficult to assess limitations and potential problems … reported, integrating those data to answer questions about treatment combinations and timing was difficult … outcomes are influenced by local practices, staffing, and other features of the environment, it is difficult … applicability discussed above, as well as the limitations of the evidence base discussed below, make it difficult … In addition, measurement in person or from tracings or photographs can be difficult, especially when

386. Disposition of Comments for Evidence Report 221 Behavioral Programs for Diabetes Mellitus (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/diabetes-behavior-programs_disposition-comments.pdf
     September 28, 2015 - need to add a statement that blinding participants and study personnel in behavioral studies is very difficult … section on limitations of the evidence base, “Blinding of participants and personnel are arguably difficult … Page 32, Table E of research gaps is very important but without the key questions listed it is more difficult … While we agree that blinding of participants and providers is difficult, the risk of bias still remains … Figures 4 and 15, risk of bias, are difficult to interpret in black and white print and most of the

387. Disposition of Comments for CER 196 The Role of Immunotherapy in the Treatment of Asthma (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-196-disposition-comments-immunotherapy-asthma.pdf
     March 23, 2018 - TEP #1 Methods It is difficult to understand how 88 RCTs of SCIT … comment #5 Karen Rance ALK Americas Results As recognized in the limitations section, it is very difficult … grading system at all, and in some cases not even descriptions of events, this made classification difficult … It is very difficult to read as it is and does not read as a discussion section, but rather a list of … While the rest of the paper is clearly organized, it is difficult to walk away with a sense that there

388. Autism-Update Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/autism-update_executive.pdf
     August 01, 2014 - children with ASD published in 2011.9 ASD intervention categories overlap substantially, and it can be difficult … studies of early intensive treatments, intervention approaches still vary substantially, which makes it difficult … measure, but a lack of consistency in the interventions studied and outcome measures used makes it difficult … available manualized interventions require high degrees of specialization and training that make them difficult … studies of early intensive treatments, intervention approaches still vary substantially, which makes it difficult

389. Disposition of Comments Report for The Effectiveness and Risks of Long-Term Opioid Treatment of Chronic Pain (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_disposition-comments.pdf
     September 29, 2014 - In some cases, the article did not report important information, making it difficult to assess its methods … for the authors to report the proportion of studies for which methods or potential limitations were difficult … For another issue, even with the information provided in Appendix E it remains difficult to appreciate … it seems incumbent on the authors to indicate the proportion of included studies for which it was difficult … Summary of evidence, difficult to read. Suggest dividing into one table for each key question.

390. The Effectiveness and Risks of Long-Term Opioid Treatment of Chronic Pain (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_executive.pdf
     September 19, 2014 - In some cases, the article did not report important information, making it difficult to assess its … versus sustained-release opioids reported inconsistent results on outcomes related to pain and are difficult … Although uncontrolled studies of patients prescribed opioids are available,8 findings are difficult … clinically significant pain relief.8 However, results of the studies included in this review are difficult … Long-term randomized trials of opioid therapy are difficult to implement due to attrition, challenges

391. Disposition of Comments for CER 201 Effectiveness of Indoor Allergen Reduction in the Management of Asthma (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-201-indoor-allergen-asthma-disposition-comments.pdf
     February 15, 2018 - However, the form is very dry and quite difficult to follow. … home (and would likely be a problem in a clinical setting, given that a challenge would likely be difficult … The manuscript notes (roughly) that this makes it difficult to resolve which factor mattered most. … However, the form is very dry and quite difficult to follow. … Again, the inclusion of 2 unrelated treatment approaches makes this document a bit more difficult to

392. Disposition of Comments Report for Strategies To Reduce Cesarean Birth in Low-Risk Women (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cesarean-birth-2010_disposition-comments.pdf
     January 01, 2010 - In a growing field there will always be new studies published, and it is difficult but necessary to … It is true that unclear reporting makes the assessment of risk of bias particularly difficult; however … October 22, 2012 16 Reviewer Section Comment Response Peer Reviewer #4 Results It was somewhat difficult … Clearly this is a difficult analysis due to the wide variety of components of the studies. … For the reviewer to pick those out as they meander through 100 pages may be difficult.

393. Methods Research Report - Framework for Determining Research Gaps During Systematic Review: Evaluation (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/research-gaps_research.pdf
     February 01, 2013 - Research gaps which are difficult to characterize into the PICOS framework should be abstracted in free … These are often gaps for which it is difficult to identify a clear intervention or comparison of interest … Research gaps which are difficult to characterize into the PICOS framework should be abstracted in free … These are often gaps for which it is difficult to identify a clear intervention or comparison of interest … At the FRN point it is almost too late; too difficult to use.

394. Wheeled Mobility (Wheelchair) Service Delivery (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/wheelchair-service_disposition-comments.pdf
     January 01, 2012 - Unfortunately, it is difficult to fund the appropriate team of professionals given the current reimbursement … Yes the references are there, but the in the body of the report this information is difficult to tease … If you are trying to show that wheeled mobility use in the US is growing it is difficult to gather … "this may be, in part, because... need to say also because equipment trial may be difficult due to … It is difficult to fully evaluate the current best clinical practice for assistive device assessment

395. PCA3 Testing in the Diagnosis and Management of Prostate Cancer: Future Research Needs (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/prostate-cancer-antigen-3-gene_research.pdf
     April 01, 2013 - It would be difficult to perform the randomized clinical trial that would be required to establish the … The panel recognized that this research need might be difficult to address, but concluded that test … Recruitment of subjects should not be difficult although future studies should learn from the comparative … Recruitment of subjects should not be difficult although future studies should learn from the comparative … These models are difficult to compare across studies and do not allow for simple inclusion of new variables

396. Treatment Strategies for Women With Coronary Artery Disease: Future Research Needs (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/cad-women-treatment-future_research.pdf
     February 01, 2013 - It would be difficult to design clinical trials to compare the influence of these different clinical … within the context of a trial, particularly if blinding must be maintained, is both expensive and difficult … The main challenge here is accessibility to the appropriate data, which may be difficult, especially … Paper records are difficult to abstract because of issues relating to legibility, consistency in diagnostic … number of respects, such as income and employment history, that may be relevant, but which may be difficult

397. Comparative Effectiveness of Medications in Patients with Epilepsy (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_disposition-comments.pdf
     March 01, 2012 - This entire section is difficult to follow. Can you please clarify. … inclusion and exclusion criteria used by the studies relevant to the topic make it extraordinarily difficult … It may be difficult to justify a switching study (which will be very difficult to implement) before … It is difficult to address this comment without additional specificity. … Because that pathology is different between patients who present with similar seizures, it is difficult

398. Impact of Healthcare Worker Safety and Wellness: A Systematic Review (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/worker-safety-wellness-protocol.pdf
     October 26, 2024 - The evidence for more distal effects, such as organizational and societal outcomes, is more difficult … unionization rates, and working hours that would make inference and generalizability to the United States difficult … Although difficult to define, patient-facing HCWs may include all those who work in the healthcare industry

399. Impact of Healthcare Worker Safety and Wellness: A Systematic Review | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/worker-safety-wellness/protocol
     December 01, 2024 - The evidence for more distal effects, such as organizational and societal outcomes, is more difficult … unionization rates, and working hours that would make inference and generalizability to the United States difficult … Although difficult to define, patient-facing HCWs may include all those who work in the healthcare industry

400. Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/plant-based-chronic-pain-treatment/living-review
     March 01, 2025 - products versus placebo to apply such methods, which indicated potential small sample effects, results are difficult … Defining clinical significance in chronic pain is difficult because it is subjective and difficult to