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Total Results: 1,316 records

Showing results for "difficult".

261. Layout 1 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_executive.pdf
     June 01, 2011 - ARB); events reported, it was difficult to discern any differential Insufficient effect of ACEIs versus … studies, and relatively small sample ARB) sizes for ARBs, the precise magnitude of this effect is difficult

262. Disposition of Comments for Management of Suspected Opioid Overdose With Naloxone by Emergency Medical Services Personnel (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-193-disposition-comments-naloxone.pdf
     November 27, 2017 - Reviewer #2 General Comments This report exhaustively and comprehensively sought answers to difficult … I would have to say that it is difficult to capture the stress and drama from the individual cases … Ryan Introduction Consider timing of administration in patient population with difficult IV access … The effect of naloxone vs, or with the airway adjuncts makes this difficult to interpret. … Longitudinal studies will be difficult, so best practices must be openly shared.

263. No-Touch Modalities for Disinfection of Hospital/Acute Care Settings: A Rapid Evidence Review | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/no-touch-disinfection/protocol
     July 01, 2020 - ) spores and infection, as a hospital acquired infection that is easily transmitted to surfaces and difficult

264. Preventing Complications and Treating Symptoms of Diabetic Peripheral Neuropathy (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/diabetic-neuropathy-disposition-170707.pdf
     March 24, 2017 - revised it TEP #2 Results - KQ1 I’m curious as to why ORs were used instead of RRs as they are more difficult … Lack of head to head trials makes comparisons between groups, such as SNRI to anticonvulsants, difficult … Unfortunately, it is difficult to gain authorization for Lidoderm (especially from Medicare plans).

265. Preventing Complications and Treating Symptoms of Diabetic Peripheral Neuropathy (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/diabetic-neuropathy-disposition-170707.pdf
     March 24, 2017 - revised it TEP #2 Results - KQ1 I’m curious as to why ORs were used instead of RRs as they are more difficult … Lack of head to head trials makes comparisons between groups, such as SNRI to anticonvulsants, difficult … Unfortunately, it is difficult to gain authorization for Lidoderm (especially from Medicare plans).

266. OUTLINE (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/cancer-end-of-life-measures-framework_research.pdf
     April 01, 2010 - indicators approved by the NQF defined the denominator retrospectively from the time of death, making it difficult … oncology, hospice) have not been well-coordinated, making combining or comparing results across settings difficult … diseases and many patients have multiple comorbidities at the end-of-life, isolating cancer issues is difficult

267. OUTLINE (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/cancer-quality-indicator-framework_research.pdf
     April 01, 2010 - indicators approved by the NQF defined the denominator retrospectively from the time of death, making it difficult … oncology, hospice) have not been well-coordinated, making combining or comparing results across settings difficult … diseases and many patients have multiple comorbidities at the end-of-life, isolating cancer issues is difficult

268. CER 215 Adverse Effects of Pharmacologic Treatments of Major Depression in Older Adults (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-215-depression-older-adults-comments.pdf
     March 28, 2019 - The format of Table B makes the findings difficult to interpret. … Table B contains nearly the full array of information resulting from the analyses, I find it rather difficult … However, this makes it difficult to use the information in determining whether a given medication is … SNRI) were originally intended to identify medication class effects, but that this was difficult due … 2nd sentence: “Further characterization of the comparative safety of first‐line antidepressants is difficult

269. Methods Research Report: Developing Consistent and Useful Quality Improvement Study Data Extraction (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/developing-consistent-useful-quality-improvement.pdf
     September 01, 2020 - Quality improvement studies can provide important insight to learning health systems (LHS) but are difficult … full spectrum of quality improvement projects completed in an area from the medical literature is difficult … The participants were first asked to rate how difficult it is to find and use quality improvement studies … On a scale of 0 to 10, the first key informant rated it a 6 (moderately difficult) while the second … reviewer rated it a 4 (moderately difficult), justified by the paucity of published quality improvement

270. Medical Therapies for Children With Autism Spectrum Disorder—An Update (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/asd-medical-executive-170505.pdf
     May 01, 2017 - reported in studies comparing these interventions were diverse, and their clinical significance is difficult … While duration was typically short, retaining participants in studies, especially in placebo arms, is difficult … This lack of reporting makes comparing harms across studies difficult. … This lack of reporting makes comparing harms across studies difficult.

271. Disposition of Comments: CER 227 Noninvasive Nonpharmacological Treatment for Chronic Pain (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-227-noninvasive-nonpharm-chronic-pain-comments.pdf
     April 16, 2020 - The presentation of treatments by each diagnosis is difficult for the reader to understand. … the likelihood that few studies would study the same combination/adjunctive therapies, it would be difficult … Response Ashley Walton, American Society of Anesthesiologists (ASA) General Recognizing that it is difficult … conduct trials of nonpharmacologic therapies because the trial sizes tend to be small, blinding is difficult … We recognize that in this type of review it is difficult to address the many different subpopulations

272. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/gerd-disposition-120104.pdf
     April 01, 2011 - modification interventions varied across studies and are usually incompletely reported, and it is difficult … The entire dataset was evaluated; however, in this subcategory (which is a very difficult category to … number or proximal extent of the refluxate, thus may not adequately control reflux.4 Thus, it is very difficult … www.effectivehealthcare.ahrq.gov 13 Commentator & Affiliation Section Comment Response esophagitis making any comparison difficult … It is difficult to ascertain the role of behavioral therapy for reflux.

273. Disposition of Comments Report for Outpatient Case Management for Adults With Medical Illness and Complex Care Needs (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/case-management_disposition-comments.pdf
     January 01, 2013 - customized nature of the interventions employed for specific conditions makes any general conclusions difficult … balance the amount of data presented with making the tables understandable – the tables would be difficult … I think it would be a very hard to come up with a ‘hard and fast definition’ for an outcome and difficult … There is absolutely a lack of research devoted to this topic, perhaps because it is difficult to determine … However, in many studies, the way in which CM is implemented is poorly described, making it difficult

274. Evidence Report on the (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/dietary-supplements_research-protocol.pdf
     December 15, 2010 - Drug-Dietary Supplement Interactions: In the clinical setting, drug-supplement interactions are more difficult … The variability in dietary supplement constituents, quality, and dosage makes it difficult to compare … evidence of interactions between dietary supplements and cardiovascular drugs are small in size and difficult … The study may be missing information, making it difficult to assess limitations and potential problems … impact of studies published in languages other than English in a meta-analysis may be minimal, it is difficult

275. Minimal Modeling Approaches to Value of Information Analysis for Health Research (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-future-value-of-information_research.pdf
     June 01, 2011 - However, predicting the value of research is difficult because the outcomes of research are inherently … uncertain and the value of those uncertain outcomes may be difficult to characterize. … For example, it may be very difficult to fully characterize the possible outcomes of a research study … Similarly, it may be difficult to meaningfully characterize the uncertainty in the net benefit of the … When it is difficult to characterize the extent to which a particular research study is likely to reduce

276. Disposition of Comments Report for Antiplatelet and Anticoagulant Treatments for Unstable Angina/Non-ST Elevation Myocardial Infarction (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/angina-heart-attack-treatments_disposition-comments.pdf
     January 01, 2014 - We are aware that such definitions are difficult because they often vary from study to study, but this … Given the number of comparisons within each key question, it would be difficult to have one overall … In contrast, the body of the document is difficult to follow. … However it is difficult to obtain a “bottom line.” Noted. … TEP Member 5 General: Clarity/usability The abstract is dense and difficult to absorb.

277. CER 221 Disposition of Comments: Pharmacologic and Nonpharmacologic Therapies in Adult Patients With Exacerbation of COPD (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-221-copd-comments_0.pdf
     October 11, 2019 - The key messages are unclear and difficult to follow. … The current formatting is difficult to read and not scannable – inconsistent with the concept behind … Peer reviewer #6 Evidence Summary 12.References. 2-column format is difficult to scan and find relevant … It is often difficult to obtain spirometry in patients with COPD exacerbations, so frequently not done

278. Information Technology Infrastructure for N-of-1 Trials (Chapter 5) | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/n-1-trials/research-2014
     August 01, 2019 - Unfortunately, existing clinical trial management systems are inadequate for managing n-of-1 trials and are difficult … writing, as many of the planned treatments, such as diet, home-supplementation, or lifestyle changes, are difficult … protect patients and improve their access to data, even if in practice it appears to make access more difficult … management systems are designed explicitly for traditional parallel group randomized trials and might be difficult

279. Thompson_ECCS2012 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/thompson_eccs2012.pdf
     January 01, 2012 - • It is difficult  to avoid this bias,  both affective  and cognitive, in real  life.

280. SRDR-Charter-140305 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/wysiwyg/data-repository-reviews-charter-140305.pdf
     June 01, 2012 - − Current methodology makes it difficult to  harness previous work  when updating SRs. − An open