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Total Results: 1,316 records

Showing results for "difficult".

241. Blood-Clots-Hip-Knee-Surgery Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/blood-clots-hip-knee-surgery_executive.pdf
     March 01, 2012 - Comparing LMWH agents with DTIs is difficult because the occurrence of DVT was greater, but the occurrence … It is difficult to discern the comparative balance of benefits and harms for oral antiplatelet therapy … It is difficult to discriminate between DVT being causative for, or colinear with, the occurrence of … direct comparative trials are needed between classes of drugs, but funding these trials could be difficult … The large number of mechanical prophylactic devices available also makes it difficult to conduct a

242. Disposition of Comments Report for Serum Free Light Chain Analysis for the Diagnosis, Management, and Prognosis of Plasma-Cell Dyscrasias (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/plasma-cell-dyscrasias-sflc-assay_disposition-comments.pdf
     August 23, 2012 - this is an entity that has no clinical symptoms and is defined only by an abnormal rFLC, it becomes difficult … LC-MGUS and agree that if the FLC ratio is the only abnormal test that signals the condition, it is difficult … Affiliation Section Comment Response Peer Reviewer #5 Results Amyloidosis is a very rare and often difficult

243. Disposition of Comments Report for Medication Adherence Interventions: Comparative Effectiveness (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/medication-adherence-interventions_disposition-comments.pdf
     September 11, 2012 - For readers interested in a general overview of adherence, this is very difficult sledding. … For example, Table 6, p. 29 of the report is very difficult to read and interpret because of its formatting … Perhaps the range of topics covered by the KQs and the heterogeneity of the literature make it difficult … All the required elements of this review make it difficult to substantially reduce the size of the … and the portions reviewed of the body of the review, are well written and concise, the abstract is difficult

244. Disposition of Comments Report for Evaluation and Treatment of Cryptorchidism (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/undescended-testicle_disposition-comments.pdf
     December 11, 2012 - primary exception to the recommendation against US is in the obese patient, in whom an inguinal UDT is difficult … boys can be challenging and the distinction between retractile and truly undescended testes can be difficult … While it is difficult to separate such cases in most literature reports on cryptorchidism/orchiopexy … While long-term studies like the ones proposed in the future research section are difficult, they are … The older literature is difficult to compare with the more recent literature, as surgical standard of

245. Disposition of Comments Report for Acute Migraine Treatment in Emergency Settings (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/migraine-emergency_disposition-comments.pdf
     November 27, 2012 - Having just reviewed this same topic myself, I am aware of how difficult it is to gather good data … I understand that it is somewhat difficult to classify as it is a weak neuroleptic, an antiemetic, and … Peer Reviewer #8 Methods Migraine headache outcomes are difficult to measure but the report provides … and neuroleptics there is no discussion of dose equivalence, making interpretation of comparators difficult … Results Page 50: In trying to find reference #101, it became apparent that this very long document is difficult

246. Disposition of Comments Report for Comparative Effectiveness Review #68 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/nppv-respiratory-failure_disposition-comments.pdf
     July 01, 2012 - Seems almost as important to me as the difficult patient sub group types. … Peer Reviewer 5 Executive Summary Page 12 [ES-4]: Fig ES 1 - is a poor reproduction and difficult … Peer Reviewer 5 Introduction Figure 1, page 37 [6] – difficult to read, please provide a more clear … This is a difficult area to characterize in review of research investigations since appropriate trained … Peer Reviewer 4 Methods 10) In the quality rating section, comparability of groups at baseline is difficult

247. Selecting Observational Studies for Comparing Medical Interventions | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/methods-guidance-observational-studies/methods
     April 01, 2022 - development of Comparative Effectiveness Reviews and describes recommended approaches for addressing difficult … RCTs may be difficult to implement due to entrenched clinical practice or to active consumer pressure … They found that fluctuating or intermittent conditions are much more difficult to assess with observational … The presence of outcome reporting bias can be difficult to determine, but may be inferred when important

248. Comparative Effectiveness of Dietary Supplement Versus No Dietary Supplement Use in Adults Taking Cardiovascular Drugs | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/dietary-supplements/research-protocol
     December 01, 2019 - Drug-Dietary Supplement Interactions: In the clinical setting, drug-supplement interactions are more difficult … The variability in dietary supplement constituents, quality, and dosage makes it difficult to compare … evidence of interactions between dietary supplements and cardiovascular drugs are small in size and difficult … The study may be missing information, making it difficult to assess limitations and potential problems … impact of studies published in languages other than English in a meta-analysis may be minimal, it is difficult

249. Long-Term Care for Older Adults Disposition of Comments Report (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/long-term-care-adults_disposition-comments.pdf
     November 07, 2012 - across states have been inconsistent because assessing the cost and effectiveness of HCBS has been difficult … This makes the comparison with home care programs even more difficult. … Reviewer #1 Results The large number of tables in the text of the report were difficult to deal with … complexity of the information and the presentation method of relying primarily on tables makes it difficult … It is difficult to estimate the impact that such a report will have for a number of reasons.

250. Disposition of Comments Report for The Patient-Centered Medical Home (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/patient-centered-medical-home_disposition-comments.pdf
     July 03, 2012 - This discrepancy is difficult to explain. … Table 22: Table 22 was easier to understand after having read the previous sections; however, it was difficult … However, measuring the impact of interventions on these outcomes is difficult because of the long period … for Medical Home Implementation Discussion The conclusions made in this report may make it more difficult … influenced, resulting in an environment in which sustaining the medical home will become increasingly difficult

251. Treatment of Osteoarthritis of the Knee: An Update Review (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/osteoarthritis-knee-update-disposition.pdf
     May 04, 2017 - after 3 dropouts) in the resistance training arm, and 9 (after 4 dropouts) in the control arm, it is difficult … Results Similarly, not displaying the number of participants in study arms makes the forest plots difficult … It's very difficult to read. … Appendix I includes it, but the table has considerable text making it a little difficult to identify … It is difficult to recommend practice or policy changes based on such limited information.

252. Treatment of Osteoarthritis of the Knee: An Update Review (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/osteoarthritis-knee-update-disposition-archived.pdf
     May 04, 2017 - after 3 dropouts) in the resistance training arm, and 9 (after 4 dropouts) in the control arm, it is difficult … Results Similarly, not displaying the number of participants in study arms makes the forest plots difficult … It's very difficult to read. … Appendix I includes it, but the table has considerable text making it a little difficult to identify … It is difficult to recommend practice or policy changes based on such limited information.

253. Disposition of Comments for CER 181 Mental Health Care (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/mental-health-children_disposition-comments.pdf
     December 19, 2016 - Peer Reviewer 1 Discussion/ Conclusion Part of the reason is that there is so little research it is difficult … The authors should be clear that this was confusing and difficult to do. So noted. … Peer Reviewer 7 General The result is a review of studies that are so disparate that it is difficult … set of papers and the reliance on qualitative analysis creates a very complex report that I found difficult … TEP 6 General Splitting the descriptions across the key questions makes it quite difficult to get a

254. PEPTIC ULCER #11 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/11_peptic_ulcer_potential_high_impact_2012-12-111.pdf
     January 01, 2012 - prolonged occlusion of the lower esophageal sphincter (LES) and reduced peristaltic activity, making it difficult … might not be as effective as laparoscopic surgery in the long term, and revisional surgery might be difficult … However, if TSO shows efficacy in that difficult-to-treat patient population, it could greatly add … it may not be as effective long term as laparoscopic surgery and that revisional surgery might be difficult … Two experts representing a clinical perspective stated that PN is difficult to administer to patients

255. Disposition of Comments for CER 222: Achieving Health Equity in Preventive Services (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-222-health-equity-preventive-services-comments.pdf
     December 03, 2019 - Seraphine Lambert Appendixes The appendixes appear very difficult to find in the review or missing.

256. Executive Summary_Systematic Review: Use of Telehealth During the COVID-19 Era (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/use-telehealth-during-COVID-19-executive-summary.pdf
     January 01, 2023 - However, telehealth may not be suitable for all patient populations, such as those who are more difficult

257. Vitamin D and Calcium: A Systematic Review of Health Outcomes (Update) | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/vitamin-d-calcium/research
     December 01, 2019 - Beyond these observations, it is difficult to make any substantive statements on the basis of the available

258. Disposition of Comments for CER 208 Treatment for Bipolar Disorder in Adults A Systematic Review (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-208-bipolar-adults-disposition-comments.pdf
     August 07, 2018 - However, it is difficult to see how the evidence can be categorized as insufficient when many hundreds … It is also quite difficult to retain patients with severe mania in studies due to typical restrictions … The nature of psychiatric illness is such that it is even more difficult to avoid attrition than in … the same challenges with high attrition as many of the other studies, making drawing conclusions difficult … For these reasons, the data are inherently difficult to digest and synthesize.

259. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/cystic-fibrosis-hgh_research-protocol.pdf
     August 22, 2008 - The study may be missing information, making it difficult to assess limitations and potential problems … While each has merit in clinical interpretation, data handling is difficult. … Absolute changes in height and weight over a broad age range may be difficult to interpret, as younger

260. S50 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/s50.pdf
     October 01, 2007 - require extensive quality control to de- crease errors in treatment delivery, but treatment purity is difficult … How- ever, if these data are not obtained using participant random- ization, it can be difficult to determine … Also, participation in higher-order or more difficult therapeutic activities seemed to improve lower-level