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Total Results: 1,316 records

Showing results for "difficult".

1301. Plasma-Cell-Dyscrasias-Sflc-Assay Executive (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/plasma-cell-dyscrasias-sflc-assay_executive.pdf
      August 01, 2012 - and heterogeneity in the comparator used, as well as a lack of data for further synthesis, made it difficult … Several limitations and potential biases in these studies make it difficult to present clear conclusions … The effects of such convenience sampling are difficult to assess.

1302. Disposition of Comments Report for Decision Aids for Cancer Screening and Treatment (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cancer-decision-support-tools_disposition-comments.pdf
      December 23, 2014 - Only recommended changes are to improve understandability of portions of the text which were difficult … These models can be difficult to fit with few studies. … As the reviewer notes, this is difficult for all the outcomes we are summarizing.

1303. Methods Guide for Comparative Effectiveness Reviews - Avoiding Bias in Selecting Studies (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-bias_methods.pdf
      February 01, 2013 - key to the development of Systematic Reviews and describes recommended approaches for addressing difficult … Composite endpoints are often difficult to interpret and may exaggerate the magnitude of treatment effect … This information is sometimes readily available, but often matching is difficult. 4.

1304. Disposition of Comments for Pressure Ulcer Treatment Strategies: Comparative Effectiveness (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/pressure-ulcer-treatment_disposition-comments.pdf
      May 08, 2013 - We admit that it is difficult to know if infection should be considered a harm or benefit (infection … To conclude a 'moderate strength of evidence' (p17) is difficult to understand on many different levels … wound (sacral/coccyx) with confounding issues such as incontinence may make strict study protocols difficult … review, complete healing was not commonly used as the outcomes measure in many studies and so it is difficult … Second, prospective, randomized clinically controlled trials of nutrition supplementation are often difficult

1305. Disposition of Comment Report for Wireless Motility Capsule Versus Other Diagnostic Technologies for Evaluating Gastroparesis and Constipation (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/wireless-motility-capsule_disposition-comments.pdf
      May 20, 2013 - It is difficult to understand the exclusion of a manuscript that compares antroduodenal manometry with … Section Comment Response TEP 5 Introduction An additional fact that deserves mention is that it is difficult … And, on page 3, we have added, "Motility disorders are difficult entities to diagnose. … as this review mentions, whether the capsule has added value in the management of these somewhat difficult … most of the available tests have some inconsistency in performance that make their interpretation difficult

1306. Disposition of Comments for CER 161 Major Depressive Disorder (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/major-depressive-disorder-disposition-160504.pdf
      December 08, 2015 - 21 line 37 This is an example where the lack of inclusion of placebo controlled trials makes it difficult … Also, we agree that this available evidence is difficult to interpret. … Although some of the heterogeneity may be due to different preparations, it is difficult to conclude … Standardization is no more difficult to assess (eg. 0.3% hypericin) than the dose of ibuprofen contained … Rather those with low depression severity respond well to a placebo arm, and it is difficult to detect

1307. Disposition of Comments for CER 177 Agitation Aggression Dementia (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/dementia-agitation-aggression_disposition-comments.pdf
      March 21, 2016 - The text now states: “The more interventions require clinical judgment, the more difficult it is to … paragraph 3 May wish to insert e.g., just after the parenthesis and before "disruptive, problem, difficult … Again, based on the text descriptions, it is difficult to ascertain what these were. … with either of 2 medications 1 behavioral intervention and 1 placebo group that excluded this most difficult … Very difficult to capture the richness and therapeutic value of this method in RCTs.

1308. Disposition of Comments Report for Chronic Venous Ulcers: A Comparative Effectiveness Review of Treatment Modalities (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/venous-ulcers-treatment_disposition-comments.pdf
      January 27, 2014 - We agree that wound measurement is difficult. … compression therapy in the treatment of venous ulcers has been the standard for many years, it is difficult … Although difficult, blinding could still be possible in these trials. … If it is there, I apologize; this was a difficult read.

1309. Crosscutting-Horizon-Scan-High-Impact-1412 (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1412.pdf
      December 01, 2014 - That undermines the statistical analysis of trial results and makes it difficult to determine the ‘ … For example, rapid triage and diagnosis—hallmarks of ED care—are difficult with older patients, who … Infrastructure and staffing: Implementation varies widely, making it difficult to determine the true … concerns may be addressed more efficiently.68,70 14 The cost impact to the health care system is difficult

1310. Preoperative-Testing Executive (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/preoperative-testing_executive.pdf
      January 01, 2014 - The complication rate in a cohort study of routine testing is difficult to interpret in the absence … They may be missing information, making it difficult to assess limitations, including risk of bias per … Limitations of Research on Preoperative Testing Another limitation of the evidence that would be difficult … Without good descriptions in studies of typical H&P or the triggers to order ad hoc tests, it is difficult

1311. Disposition of Comments Report for Comparative Effectiveness Review No. 137 (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/autism-update_disposition-comments.pdf
      August 06, 2014 - We agree that this is an issue in this literature that makes it very difficult to answer this important … Until this can be achieved it remains difficult to make informed decisions about the relative value … As such, it can be difficult to assess the level of qualifications and training of frontline staff. … The check marks and blanks are difficult to interpret (e.g., do checks indicate that there is evidence

1312. Disposition of Comments for Strategies To Prevent Weight Gain Among Adults (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/weight-gain-prevention_disposition-comments.pdf
      March 25, 2013 - Peer Reviewer 1 General Conceptually, it is difficult to understand how a weight gain prevention … weight is clearly different than those who have never been overweight as evidenced by the extreme difficult … weight is clearly different than those who have never been overweight as evidenced by the extreme difficult … NHLBI) Methods The majority of trials reviewed were not designed to prevent weight gain making it difficult

1313. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/fetal-surgery_disposition-comments.pdf
      July 05, 2011 - Peer Reviewer #7 Results The entire paragraph on the „physiology‟ of amnioticfluid is a little difficult … Often times the more difficult judgements to be made during pregnancy are the frequency with which … recent years We have changed the text to note that "distinguishing between these conditions is difficult … impact her future long term health – are there more adhesions that may make subsequent surgeries more difficult

1314. Disposition of Comments for CER 167 Renal Masses (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/renal-cancer_disposition-comments.pdf
      February 24, 2016 - necessarily proceed to surgical extirpation, limiting the analysis and making the exact false negative rate difficult … necessarily proceed to surgical extirpation limiting the analysis and making the exact false negative rate difficult … proceed to surgical extirpation, limiting the analysis and making the exact false negative rate difficult … Space limitations make it difficult to report the full results of each individual study.

1315. Disposition of Comments Report for CER 207 on PTSD (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-207-ptsd-disposition-comments.pdf
      May 17, 2018 - I understand that it may appear to be difficult to come up with a theoretically-driven, rational scheme … Why limit the usability of the report or make it difficult for readers to compare the findings in the … related to RoB coding, in Table E-25 in Appendix E, the entry for Schnurr et al. 2007 reflects another difficult … It was also difficult to find the relevant results/findings that would be needed to make a decision

1316. Hepatitis-C-Screening Executive (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/hepatitis-c-screening_executive.pdf
      November 01, 2012 - proportion of patients in the general population with HCV infection who progress to cirrhosis is difficult … The study may be missing information, making it difficult to assess its methods or assess limitations … diagnosed with HCV infection suggested potential negative psychological and social effects, but are difficult … reporting rates of antiviral treatment in cohorts of patients with screen-detected HCV infection are also difficult