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41. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/coronary-artery-stenting_research-protocol.pdf
    August 19, 2011 - Practice Center Systematic Review Protocol Project Title: Comparative Effectiveness of Intravascular Diagnostic … We plan to evaluate the impact of IVDx techniques on the diagnostic thinking of physicians. … a) During diagnostic coronary angiography for the evaluation of the presence/extent of CAD and the … Diagnostic thinking and therapeutic decisionmaking outcomes include: • KQ 1: During diagnostic workup … Challenges in systematic reviews of diagnostic technologies. Ann Intern Med 2005;142:1048-55.

42. Liver-Cancer Research-Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/liver-cancer_research-protocol.pdf
    July 24, 2013 -  Intermediate outcomes include:  Effects on diagnostic thinking. … Diagnostic Imaging/ 5. Ultrasonography/ 6. … Meta-analyses of measures of diagnostic outcomes (including diagnostic accuracy) and clinical and patient-centered … Intermediate outcomes include: • Effects on diagnostic thinking. … Intermediate outcomes include: • Effects on diagnostic thinking.

43. Effective Health Care (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0359_10-15-2010.pdf
    January 01, 2010 - Diagnosis of multiple sclerosis was found to be addressed by a 2011 systematic review on the accuracy of diagnostic … Accuracy of diagnostic tests in multiple sclerosis—a systematic review. … cerebrospinal fluid testing, evoked potentials, clinical findings Comparator(s): Comparison of diagnostic … techniques alone or in combination Outcome(s): Diagnostic accuracy, time to diagnosis, patient-oriented … of MS is largely covered by a 2011 systematic review by Shaffler and colleagues titled Accuracy of Diagnostic

44. Diagnosis and Treatment of Clinical Alzheimer's-type Dementia (CATD) (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/catd-protocol-draft_0.pdf
    November 02, 2018 - Information extracted only from diagnostic studies will include diagnostic test, reference test, and … measures of diagnostic performance assessed. … , CSF, blood), within each diagnostic test category by specific test, and then by diagnostic accuracy … Diagnostic and Statistical Manual of Mental Disorders: DSM-5; 2013. 11. … Chapter 7: grading a body of evidence on diagnostic tests.

45. Disposition of Comments Report for Intravascular Diagnostic Procedures and Imaging Techniques Versus Angiography Alone in Coronary Artery Stenting (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/coronary-artery-stenting_disposition-comments.pdf
    February 26, 2013 - Disposition of Comments Report for Intravascular Diagnostic Procedures and Imaging Techniques Versus … Intravascular Diagnostic Procedures and Imaging Techniques Versus Angiography Alone in Coronary Artery … together even though the respective diagnostic techniques serve different purposes. … The evaluation of diagnostic accuracy of FFR is not part of scope of this report. … We did not include studies that were conducted solely for diagnostic accuracy.

46. Plasma-Cell-Dyscrasias-Sflc-Assay Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/plasma-cell-dyscrasias-sflc-assay_executive.pdf
    August 01, 2012 - Our goals were to evaluate the SFLC assay as an add-on test in diagnostic settings and to compare it … This CER evaluates the SFLC assay as a diagnostic and prognostic tool adjunctive to the standard diagnostic … studies—STAndards for the Reporting of Diagnostic accuracy studies (STARD, www.stard-statement.org … , although the effect on diagnostic specificity was inconsistent. … How to use an article about a diagnostic test. B.

47. Meta-analysis of Test Performance Evidence When There is a “Gold Standard” Reference Standard (ppt file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-meta-analysis.ppt
    June 01, 2012 - The diagnostic odds ratio is a measure of the effectiveness of a diagnostic test. … The higher the diagnostic odds ratio, the higher the diagnostic accuracy. … Regression methods for meta-analysis of diagnostic test data. … Regression methods for meta-analysis of diagnostic test data. … Regression methods for meta-analysis of diagnostic test data.

48. Meta-analysis of Test Performance Evidence When There is a “Gold Standard” Reference Standard (ppt file)
    effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-meta-analysis.ppt
    June 01, 2012 - The diagnostic odds ratio is a measure of the effectiveness of a diagnostic test. … The higher the diagnostic odds ratio, the higher the diagnostic accuracy. … Regression methods for meta-analysis of diagnostic test data. … Regression methods for meta-analysis of diagnostic test data. … Regression methods for meta-analysis of diagnostic test data.

49. Glaucoma-Screening Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-screening_executive.pdf
    April 01, 2012 - HRT II was a diagnostic test of interest in three studies. … HRT II and HRT III were found to have a similar diagnostic profile. … Ten studies examined the diagnostic accuracy of the HFA. … The risk of bias of diagnostic study designs is an additional concern. … Diagnostic ability of the Heidelberg Retina Tomograph 3 for glaucoma.

50. Methods Guide for Medical Test Reviews (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-metaanalysis_methods.pdf
    July 01, 2012 - Challenges in systematic reviews of diagnostic technologies. … Guidelines for meta-analyses evaluating diagnostic tests. … Regression methods for meta-analysis of diagnostic test data. … Cochrane Diagnostic Test Accuracy Working Group. … Handbook for diagnostic test accuracy reviews. 2011.

51. genetic-testing-developmental-disabilities-protocol-140930 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/genetic-testing-developmental-disabilities_research-protocol.pdf
    September 30, 2014 - Most studies reported a test’s diagnostic yield and none investigated a test’s diagnostic accuracy … Genomic microarrays in mental retardation: a practical workflow for diagnostic applications. … Diagnostic utility of array-based comparative genomic hybridization in a clinical setting. … Flourescent In Situ Hybridization (FISH) as a diagnostic tool for Williams-Beuren Syndrome. … Evaluating diagnostic accuracy of genetic profiles in affected offspring families.

52. Methods Guide for Medical Test Reviews (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-bias_methods.pdf
    July 01, 2012 - Sources of variation and bias in studies of diagnostic accuracy: a systematic review. … Development and validation of methods for assessing the quality of diagnostic accuracy studies. … Cochrane Methods Working Group on Systematic Review of Screening and Diagnostic Tests. … Empirical evidence of design-related bias in studies of diagnostic tests. … Systematic reviews of diagnostic test accuracy. Ann Intern Med. 2008;149(12):889-97. 12.

53. Cad-Women-Diagnosis Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-women-diagnosis_executive.pdf
    June 01, 2012 - Studies assessing outcomes beyond diagnostic accuracy. … Assessing clinical and demographic factors that influence diagnostic accuracy. … Current diagnostic concepts to detect coronary artery disease in women. … Regression methods for meta-analysis of diagnostic test data. … Low diagnostic yield of elective coronary angiography.

54. Effective Health Care (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0351_05-10-2010.pdf
    January 01, 2010 - Staff-Generated PICO Population(s): patients with cryptorchidism (undescended testicle) Intervention(s): diagnostic … techniques, early treatment, follow-up care, counseling of patient’s parents/guardian Comparator(s): diagnostic … non-treatment, timing of treatment, medical therapies, different surgical techniques Outcome(s): diagnostic … What is the ideal diagnostic workup for accurate identification of cryptorchidism? … Despite its prevalence, there is considerable uncertainty regarding appropriate diagnostic approaches

55. Breast-Abnormalities-Tests-Update Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-abnormalities-tests-update_executive.pdf
    February 01, 2012 - 1 Comparative Effectiveness Review Number 47 Noninvasive Diagnostic Tests for Breast Abnormalities … Ultrasound We identified a total of 31 diagnostic cohort studies of ultrasound. … Effectiveness of noninvasive diagnostic tests for breast abnormalities. … A unification of models for meta-analysis of diagnostic accuracy studies. … Noninvasive Diagnostic Tests for Breast Abnormalities: Update of a 2006 Review.

56. Hepatic-Fibrosis White-Paper (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatic-fibrosis_white-paper.pdf
    April 01, 2014 - Research White Paper Impact of Contacting Study Authors on Systematic Review Conclusions: Diagnostic … However, our review of diagnostic blood tests 5 had limitations. … Diagnostic value in the assessment of disease activity and fibrosis. … How to use an article about a diagnostic test. B. … Diagnostic value in the assessment of disease activity and fibrosis.

57. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-diagnosis_research-protocol.pdf
    June 06, 2011 - For intermediate-risk patients, clinicians have a wide range of noninvasive diagnostic modalities to … However, it is not clear whether the diagnostic accuracy or the relative balance of benefits and harms … KQ 3: Is there evidence that the use of NITs (when compared to other NITs or to diagnostic cardiac … Current diagnostic concepts to detect coronary artery disease in women. … Radiation risk from coronary artery disease imaging: how do different diagnostic tests compare?

58. Comparative Effectiveness Research Review Disposition of Comments Report (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-abnormalities-tests-update_disposition-comments.pdf
    February 13, 2012 - Noninvasive Diagnostic Tests for Breast Abnormalities: Update of a 2006 Review. … what is meant by “aggressive diagnostic testing”? This seems very opinionated. … We have modified the text to remove the phrase “aggressive diagnostic testing.” … Diagnostic mammography is the standard of care. … diagnostic mammographic and ultrasound work- up.

59. celiac-disease-protocol-140612 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/celiac-disease_research-protocol.pdf
    June 12, 2014 - The validity and acceptability of the various diagnostic testing regimens and criteria have remained … A number of diagnostic methods have been developed; they include various serology tests, HLA typing, … c- length of time ingesting gluten before diagnostic testing? … underwent both an intervention diagnostic method and a comparator diagnostic method (as listed in the … Appendix CELIAC DISEASE SEARCH METHODOLOGY KQ1 (DIAGNOSTIC METHODS): SEARCH #1 (DIAGNOSTIC

60. Diagnostic Accuracy of Screening and Treatment of Post–Acute Coronary Syndrome Depression: A Systematic Review. Evidence Summary. (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-200-post-acs-depression.pdf
    November 01, 2017 - Diagnostic Accuracy of Screening and Treatment of Post–Acute Coronary Syndrome Depression: A Systematic … Comparative Effectiveness Review Number 200 Diagnostic Accuracy of Screening and Treatment of Post–Acute … The objectives of the systematic review are: • To evaluate the diagnostic accuracy of selected depression … Results KQ 1: Diagnostic Accuracy of Depression Screening Tests in Post-ACS Patients We identified … Diagnostic Accuracy of Screening and Treatment of Post– Acute Coronary Syndrome Depression: A Systematic