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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-protocol.pdf
    June 05, 2024 - KQ 3: Adults undergoing diagnostic evaluation for possible cancer or cancer recurrence. … However, only diagnostic performance designs conducted in external validation cohorts are eligible. … Cochrane Handbook for Systematic Reviews of Diagnostic Test Accuracy. … https://training.cochrane.org/handbook-diagnostic-test-accuracy/current. … QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies.
  2. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-executive.pdf
    December 01, 2009 - screening mammography or physical examination, women typically undergo additional imaging studies (diagnostic … Studies of diagnostic test performance compare the results of the experimental test to a reference test … Studies of diagnostic test performance were examined to see if they met the inclusion criteria. … In general, the smaller the negative likelihood ratio, the more accurate 4 the diagnostic test is … Women with negative core- needle biopsies should have careful diagnostic followup wth clinical correlation
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-fatigue_research-protocol.pdf
    May 01, 2014 - What are widely accepted diagnostic methods and what conditions are required to be ruled out or excluded … What is the accuracy and concordance of diagnostic methods? c. … accuracy studies and diagnostic concordance studies with comparators • For KQ2: Placebo or no treatment … ; concordance, any potential harm from diagnosis (such as psychological harms, labeling, risk from diagnostic … Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition, Diagnostic and
  4. effectivehealthcare.ahrq.gov/sites/default/files/developmental-delays-horizon-scan-high-impact-1412.pdf
    December 01, 2014 - Research, AHRQ is interested in innovations in drugs and biologics, medical devices, screening and diagnostic … scanning pertains to identification of new (and new uses of existing) pharmaceuticals, medical devices, diagnostic … foundations of developmental disorders and regularly publish findings that may lead to new therapeutic and diagnostic
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-atrial-fibrillation_research-protocol.pdf
    January 30, 2012 - accuracy and impact on clinical decisionmaking (diagnostic thinking, therapeutic efficacy, and patient … decisionmaking (diagnostic thinking, therapeutic efficacy, and patient outcome efficacy) of clinical … accuracy efficacy  Diagnostic thinking efficacy  Therapeutic efficacy  Patient outcome efficacy … accuracy efficacy o Diagnostic thinking efficacy o Therapeutic efficacy o Patient outcome efficacy … QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies.
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-533_05-24-2013.pdf
    January 01, 2013 - and alternative approaches to endoscopy Comparator(s): Endoscopic small bowel biopsy Outcome(s): Diagnostic … include the other aspects that were addressed in the original report and to ensure a link between diagnostic
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/lung-cancer-staging_research-protocol.pdf
    December 08, 2014 - Thus, while imaging plays a key role in the diagnostic workup, these tests cannot be used to definitively … QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies. … A unification of models for meta-analysis of diagnostic accuracy studies. … Grading a body of evidence on diagnostic tests (AHRQ publication no. 12-EHC079-EF). … Were the people determining the reference standard unaware of the diagnostic test results?
  8. effectivehealthcare.ahrq.gov/sites/default/files/pregnancy-horizon-scan-high-impact-1406.pdf
    June 01, 2014 - Research, AHRQ is interested in innovations in drugs and biologics, medical devices, screening and diagnostic … scanning pertains to identification of new (and new uses of existing) pharmaceuticals, medical devices, diagnostic … utero surgical procedures for repairing congenital abnormalities of the heart and diaphragm, one diagnostic
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/acs-depression-research-protocol-amended.pdf
    February 15, 2017 - We will order our findings by treatment or diagnostic comparison and then within these comparisons by … For meta- analyses summarizing the sensitivity and sensitivity of diagnostic rests, convergence problems … The Diagnostic Inventory for Depression: a self-report scale to diagnose DSM-IV major depressive disorder … QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies. … Grading quality of evidence and strength of recommendations for diagnostic tests and strategies.
  10. effectivehealthcare.ahrq.gov/products/coronary-artery-stenting/research
  11. effectivehealthcare.ahrq.gov/products/wireless-motility-capsule/research
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/antibiotics-respiratory-infection_executive.pdf
    January 01, 2016 - Does the comparative effectiveness differ according to the diagnostic method or definition used, the … clinician’s perception of the patient’s illness severity, or the clinician’s diagnostic certainty? … Any point-of-care tests that are available and used in primary care settings for diagnostic purposes … resource use, diagnostic coding shifts. … When reported, diagnostic accuracy was consistent for rapid viral and strep tests.
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/glaucoma-screening_research-protocol.pdf
    November 16, 2010 - This review will also include a summary of the diagnostic accuracy of screening examinations/tests … Key Question 3 explores comparisons of screening/diagnostic tests to the gold/reference standards of … We will search MEDION (www.mediondatabase.nl) for related diagnostic accuracy reviews (Key Question … For Key Question 3, we will calculate diagnostic odds ratios. … The development of QUADAS: a tool for the quality assessment of studies of diagnostic accuracy included
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-introduction_methods.pdf
    July 01, 2012 - the ability of a test to conform to technical specifications, to accurately classify patients into diagnostic … on methods for evaluating tests to determine the current presence of disease, as with screening or diagnostic … Challenges in systematic reviews of diagnostic technologies. … When is measuring sensitivity and specificity sufficient to evaluate a diagnostic test, and when do … The efficacy of diagnostic imaging. Med Decis Making 1991;11(2):88-94. 22.
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-illness-disparities_research-protocol.pdf
    July 01, 2015 - Firstly, that within the SMI population, disparities exist in relation to (a) access to accurate diagnostic … may address one or more of the following concerns within an SMI subgroup: (a) access to accurate diagnostic … Intervention may address one or more of the following concerns: (a) access to accurate diagnostic evaluation … Interventions may address one or more of the following concerns: (a) access to accurate diagnostic evaluation … depression; (4) anxiety disorders; (5) eating disorders; or (6) personality disorders, per DSM-IV (Diagnostic
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-cancer-staging_research-protocol.pdf
    May 20, 2013 - Empirical evidence of design-related bias in studies of diagnostic tests. … QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies. … A unification of models for meta-analysis of diagnostic accuracy studies. … Were readers of the diagnostic test of interest blinded to all other clinical information? 9. … If the study reported data for a single diagnostic threshold, was the threshold chosen a priori?
  17. effectivehealthcare.ahrq.gov/sites/default/files/06_devdelays_autism_potential_high_impact_june_2012.pdf
    January 01, 2012 - Research, AHRQ is interested in innovations in drugs and biologics, medical devices, screening and diagnostic … scanning pertains to identifying new (and new uses of existing) pharmaceuticals, medical devices, diagnostic … However, additional observational studies are needed before relying on expensive diagnostic tools such
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/c-diff-infections-surveillance-140925.pdf
    January 01, 2014 - The diagnostic testing mechanisms, preventative interventions, treatment medications, and adjunctive … diagnostic trials. … AND diagnostic accuracy.mp. … specificity of the diagnostic tests marked differences in their sensitivity. … Overall, diagnostic accuracy is variable and depends on CDI prevalence.
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-test_disposition-comments.pdf
    April 01, 2013 - The outcomes measured appear to be appropriate, as is their definitions and diagnostic criteria. … (p. 38) PR # 7 Methods In the assessment of diagnostic accuracy, we are told that the distributions … All the studies appeared to address the issue of diagnostic accuracy in one or more of the contexts … With regard to comparison of diagnostic accuracy of these comparators with PCA3, that is correct. … So many diagnostic accuracy studies in oncology suffer from the biases in these articles.
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/echocardiography_research.pdf
    May 01, 2014 - Rates of echocardiography and noninvasive diagnostic imaging are lower in the Northern U.S. and higher … radiology IDTF = Independent Diagnostic Testing Facility. … Bending the curve: the recent marked slowdown in growth of noninvasive diagnostic imaging. … Multiple procedure reduction on the technical component (TC) of certain diagnostic imaging procedures … The effect of self-referral on utilization of advanced diagnostic imaging.

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