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21. Cell-Free-Dna-Final-App-C (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-final-app-c.xlsx
    January 01, 2025 - U.S. and Canada Diagnostic performance (case-control) Third of 3 substudies within the CCGA study. … NR NR NR Private funding from Berthold von und zu Zwerger Austria Diagnostic performance (case-control … A total of 57 multicancer diagnostic markers and 873 cancer signal of origin markers were used. cfDNA … Luan 2023 Diagnostic CC Aggregate cancers Six protein marker panel OncoSeek Validation cohort 2 (U.S) … Luan 2023 Diagnostic CC Aggregate cancers Six protein marker panel OncoSeek Validation cohort 2 (U.S)

22. Methods Guide for Medical Test Reviews Chapter 7 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-grading_methods.pdf
    July 01, 2012 - Our focus will be on diagnostic tests, meaning tests that are used in the diagnostic and management … of a diagnostic test on clinical outcomes, there is often no direct linkage between the diagnostic accuracy … A body of evidence evaluating diagnostic test outcomes such as diagnostic thinking, therapeutic choice … high diagnostic accuracy. … high diagnostic accuracy.

23. PROPOSALS FOR A PHASED EVALUATION OF (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/medical-tests-proposals_research.pdf
    January 01, 2009 - Common phases are evaluations of technical efficacy, diagnostic accuracy, diagnostic thinking efficacy … Diagnostic Accuracy Diagnostic accuracy plays a central role in most proposals. … Diagnostic-Thinking Efficacy Because diagnostic tests are often remote from health outcome, in the short … How to evaluate a diagnostic marker test. … The evaluation of diagnostic tests: evidence on technical and diagnostic accuracy, impact on patient

24. PROPOSALS FOR A PHASED EVALUATION OF (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/whitepaper3-lijmer02262010-2.pdf
    January 01, 2009 - Common phases are evaluations of technical efficacy, diagnostic accuracy, diagnostic thinking efficacy … Diagnostic Accuracy Diagnostic accuracy plays a central role in most proposals. … Diagnostic-Thinking Efficacy Because diagnostic tests are often remote from health outcome, in the short … How to evaluate a diagnostic marker test. … The evaluation of diagnostic tests: evidence on technical and diagnostic accuracy, impact on patient

25. Test-Performance-Metrics Appendixes (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/test-performance-metrics_appendixes.pdf
    January 01, 2005 - Diagnostic Odds Ratio The diagnostic odds ratio (DOR) describes the odds of a positive test in those … This is partly because they are not often exposed to diagnostic odds ratios. … Challenges in systematic reviews of diagnostic technologies. … How to use an article about a diagnostic test. B. … The diagnostic odds ratio: a single indicator of test performance.

26. Methods Guide for Medical Test Reviews Chapter 4 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-search_methods.pdf
    July 01, 2012 - ,26 all possible diagnostic tests were not known. … Identifying relevant diagnostic studies in MEDLINE. … Identifying diagnostic studies in MEDLINE: reducing the number needed to read. … Identifying diagnostic accuracy studies in EMBASE. … Diagnostic test systematic reviews: Bibliographic search filters ("clinical queries") for diagnostic

27. Appendicitis Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/appendicitis_executive.pdf
    December 01, 2015 - Test Performance of Multivariable Diagnostic Scores Information on one or more multivariable diagnostic … The majority of multivariable diagnostic scores were developed prior to the widespread use of diagnostic … 53 diagnostic cohort studies. … tests except diagnostic laparoscopy. … Surgical Complications in Studies of Diagnostic Laparoscopy Thirty-four studies of diagnostic laparoscopy

28. Topic 0438 Risk stratification and CAD NSD FINAL_SJ-2 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0520-131115.pdf
    May 29, 2025 - While the test performance characteristics for each of these diagnostic strategies are known, the relative … Key Questions What are the comparative diagnostic … accuracy, diagnostic thinking, and therapeutic and from Nominator: patient outcome efficacy of NITs … asymptomatic populations, and looked at outcomes other than test performance (e.g., clinical outcome, diagnostic

29. Wireless-Motility-Capsule Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/wireless-motility-capsule_executive.pdf
    May 01, 2013 - Evaluation of Gastric Dysmotility: WMC in Combination With Other Diagnostic Tests Versus Other Diagnostic … scintigraphy Diagnostic accuracy Low 7 Diagnostic accuracy of WMC is similar to scintigraphy. … scintigraphy Diagnostic accuracy Low 2 Adding WMC to conventional motility testing improves diagnostic … ROM Diagnostic accuracy Low 5 Diagnostic accuracy of WMC is similar to ROM. … KQ 4 WMC in combination with other diagnostic tests vs. other tests alone Diagnostic accuracy

30. Gout Executive-2016 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/gout_executive-2016.pdf
    January 01, 2016 - criteria were presented (updating the 2006 EULAR diagnostic criteria). … of patient population and duration of disease in determining diagnostic criteria. … Likewise, a number of the clinical diagnostic criteria, including the Diagnostic Rule and the 2014 ACR … Dual-energy CT for the diagnosis of gout: an accuracy and diagnostic yield study. … The diagnostic value of the proposal for clinical gout diagnosis (CGD).

31. Searching for Studies (ppt file)
    effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-search-strategies.ppt
    June 01, 2012 - Identifying relevant diagnostic studies in MEDLINE. … Identifying relevant diagnostic studies in MEDLINE. … Identifying relevant diagnostic studies in MEDLINE. … , all possible diagnostic tests were not known. … Identifying relevant diagnostic studies in MEDLINE.

32. Breast-Abnormalities-Tests-Update Research-Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-abnormalities-tests-update_research-protocol.pdf
    July 01, 2010 - Effectiveness of Noninvasive Diagnostic Tests for Breast Abnormalities. … Diagnostic and Interventional Radiology Department: Basic Imaging: Mammography. … Systematic reviews of evaluations of diagnostic and screening tests. … Empirical evidence of design-related bias in studies of diagnostic tests. … A unification of models for meta-analysis of diagnostic accuracy studies.

33. Appendicitis Research-Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/appendicitis_research-protocol.pdf
    December 09, 2013 - Impact on diagnostic thinking (e.g., change in diagnosis after testing; change in subsequent diagnostic … Guidelines for Diagnostic Laparoscopy. … The efficacy of diagnostic imaging. Med Decis Making. 1991 Apr-Jun;11(2):88-94. … Appendicitis in the young child: a continuing diagnostic challenge. … QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies.

34. Disposition of Comments_Comparative Effectiveness Review No. 249: Malnutrition in Hospitalized Adults: A Systematic Review (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-249-malnutrition-disposition-comments_0_0.pdf
    October 13, 2021 - This recommendation applies to observational, RCT, and diagnostic and prognostic studies. … Another design could utilize all types of diagnostic assessments for “at-risk” patients, given that … assessments versus control group to determine effectiveness of diagnostic assessment tools. … Thank you for highlighting the importance of distinguishing screening and diagnostic assessment. … Table 3 PICOTS also addresses diagnostic assessment. Thank you for highlighting this.

35. Coronary-Artery-Stenting Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/coronary-artery-stenting_executive.pdf
    February 01, 2013 - 1 Comparative Effectiveness Review Number 104 Intravascular Diagnostic Procedures and Imaging Techniques … While intravascular diagnostic techniques do provide additional anatomic or hemodynamic information … on outcomes, as compared with angiography alone (or other intravascular diagnostic techniques). … • No studies compared the use of other intravascular diagnostic techniques besides FFR. … • No studies compared the use of other intravascular diagnostic techniques besides IVUS.

36. Layout 1 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-abnormalities-tests_executive.pdf
    February 01, 2006 - Because an abnormal screening mammogram requires a diagnostic test to confirm whether cancer is present … , many women who do not have cancer will undergo diagnostic tests. … If a noninvasive diagnostic test were available that could accurately exclude malignancy, many women … An ideal diagnostic test to evaluate breast abnormalities found by mammography or breast examination … Effectiveness of Noninvasive Diagnostic Tests for Breast Abnormalities.

37. Disposition of Comments for CER 157 Appendicitis (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/appendicitis_disposition-comments.pdf
    December 14, 2015 - diagnostic test. … diagnostic error. … Peer Reviewer #1 Results For diagnostic imaging there is a problem how to treat non-diagnostic scans … Diagnostic laparoscopy versus immediate appendectomy. One advantage of laparoscopy is diagnostic. … I think you need to differentiate how diagnostic tests are used when you evaluate their diagnostic

38. PowerPoint Presentation (ppt file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-risk-bias.ppt
    June 01, 2012 - Whiting et al. (2004) conducted a review of bias in diagnostic test studies. … Empirical evidence of design-related bias in studies of diagnostic tests. … Empirical evidence of design-related bias in studies of diagnostic tests. … Empirical evidence of design-related bias in studies of diagnostic tests. … applicability in diagnostic accuracy studies A tool used to assess random error in diagnostic accuracy

39. PowerPoint Presentation (ppt file)
    effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-risk-bias.ppt
    June 01, 2012 - Whiting et al. (2004) conducted a review of bias in diagnostic test studies. … Empirical evidence of design-related bias in studies of diagnostic tests. … Empirical evidence of design-related bias in studies of diagnostic tests. … Empirical evidence of design-related bias in studies of diagnostic tests. … applicability in diagnostic accuracy studies A tool used to assess random error in diagnostic accuracy

40. Disposition of Comments Report for Imaging Techniques for the Diagnosis and Staging of Hepatocellular Carcinoma (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer_disposition-comments.pdf
    October 23, 2014 - What are “comparative effects on diagnostic thinking”? … If not explain diagnostic thinking-p 30 line 20 We revised this to be clearer that diagnostic thinking … other than diagnostic testing accuracy, including costs.” … (e.g., use of diagnostic tests and treatments). … as noted by the Cochrane Diagnostic Test Accuracy review group and others.