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141. Noninvasive Diagnostic Tests for Breast Abnormalities: Update of a 2006 Review | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/breast-abnormalities-tests-update/research

142. Celiac-Disease Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/celiac-disease_executive.pdf
     January 01, 2016 - Diagnostic Strategies A number of diagnostic methods have been developed; the validity and acceptability … Length of time ingesting gluten before diagnostic testing? Key Question 3. … Diagnostic methods no longer recommended or still in development were excluded. … QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies. … Diagnostic tests 4: likelihood ratios. BMJ. 2004 Jul 17;329(7458):168-9. PMID: 15258077. 18.

143. Diagnosis and Treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-fatigue_executive.pdf
     July 01, 2016 - For questions regarding diagnostic methods, studies were included that compared case definitions (e.g … Diagnostic methods were evaluated in eight descriptive studies comparing case definitions, although … • Diagnostic instruments: Future studies evaluating the capability of diagnostic methods for ME/CFS … A comparison of the 1988 and 1994 diagnostic criteria for chronic fatigue syndrome. … Diagnostic accuracy of symptoms characterising chronic fatigue syndrome.

144. Executive Summary_Blood-Based Tests for Multiple Cancer Screening: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-executive-summary.pdf
     May 01, 2025 - of Full Report) Accuracy (sensitivity, specificity, AUC) 13 case-control studies reporting diagnostic … Insufficient 5-Harms of Diagnostic Evaluation CancerSEEK Serious adverse events 1 single-arm … A systematic review classifies sources of bias and variation in diagnostic test accuracy studies. … Case-control and two-gate designs in diagnostic accuracy studies. Clin Chem. … Evidence of bias and variation in diagnostic accuracy studies. CMAJ. Feb 14 2006;174(4):469-76.

145. Gestational-Diabetes-Screening-Diagnosis Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/gestational-diabetes-screening-diagnosis_executive.pdf
     October 01, 2012 - Screening and Diagnostic Strategies The 2008 U.S. … characteristics and prevalence of current screening and diagnostic tests for GDM. … Studies used different diagnostic criteria and could not be pooled. … Single studies compared the diagnostic characteristics of different pairs of diagnostic criteria in … Gestational diabetes diagnostic criteria: long-term maternal follow-up.

146. Breast-Biopsy-Update Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_executive.pdf
     September 01, 2014 - Two issues related to the definition of diagnostic test categories merit additional description. … QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies. … Development and validation of methods for assessing the quality of diagnostic accuracy studies. … Evaluation of QUADAS, a tool for the quality assessment of diagnostic accuracy studies. … A hierarchical regression approach to meta-analysis of diagnostic test accuracy evaluations.

147. Noninvasive Testing for Coronary Artery Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/coronary-artery-disease-testing_research-protocol.pdf
     January 15, 2015 - Historically, invasive coronary angiography (ICA) has been considered the standard reference diagnostic … Because of the cost and risk of ICA, noninvasive testing is more appropriate as a first-line diagnostic … Noninvasive diagnostic tests can be broadly divided into two categories: functional tests and anatomic … The intended focus is on clinical outcomes and clinical pathways following the first diagnostic test … criteria or on established diagnostic criteria will be prognosis sought.

148. FRN 41 - Noninvasive Technologies for the Diagnosis of Coronary Artery Disease in Women: Future Research Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-diagnosis-future_research_1.pdf
     February 01, 2013 - 14 Are women getting the same diagnostic testing as men? … Are women getting the same diagnostic testing as men? … ) described diagnostic accuracy, and 9 of these examined predictors of diagnostic accuracy of different … Are women getting the same diagnostic testing as men? … Are women getting the same diagnostic testing as men?

149. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/procalcitonin_research-protocol.pdf
     September 08, 2011 - Procalcitonin’s primary diagnostic utility is thought to be in establishing the presence of bacterial … The diagnostic utility of procalcitonin is limited in fungal infections because the levels do not rise … Other reviews may not have used systematic methods or investigated diagnostic or therapy-monitoring … An early link in an indirect chain of evidence concerns the diagnostic accuracy of testing (B). … The quality of included diagnostic accuracy studies will be assessed by the Quality Assessment of Diagnostic

150. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0262_05-11-2007.pdf
     January 01, 2007 - Nomination Summary: The nominator questions the effectiveness and comparative effectiveness of diagnostic … What constitutes an adequate diagnostic evaluation on which to base treatment of UI? 2. … since the last search date of the AHRQ review listed above (March 2007) identified 9 trials related to diagnostic

151. PowerPoint Presentation (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-frameworks.ppt
     June 01, 2012 - The evaluation of diagnostic tests: evidence on technical and diagnostic accuracy, impact on patient … FFDM may have a similar recall rate and diagnostic yield at least as high as SFM. … The evaluation of diagnostic tests: evidence on technical and diagnostic accuracy, impact on patient … The evaluation of diagnostic tests: evidence on technical and diagnostic accuracy, impact on patient … The evaluation of diagnostic tests: evidence on technical and diagnostic accuracy, impact on patient

152. PowerPoint Presentation (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-frameworks.ppt
     June 01, 2012 - The evaluation of diagnostic tests: evidence on technical and diagnostic accuracy, impact on patient … FFDM may have a similar recall rate and diagnostic yield at least as high as SFM. … The evaluation of diagnostic tests: evidence on technical and diagnostic accuracy, impact on patient … The evaluation of diagnostic tests: evidence on technical and diagnostic accuracy, impact on patient … The evaluation of diagnostic tests: evidence on technical and diagnostic accuracy, impact on patient

153. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/heart-failure-natriuretic-peptide_research-protocol.pdf
     December 20, 2011 - Although the original 2006 review addressed these issues, the number of primary studies in the diagnostic … To summarize the current body of scientific knowledge, this review will examine the diagnostic and … No gold standard diagnostic criteria exist in HF, so we will calculate sensitivity and specificity … In the context of diagnostic accuracy studies, there are unlikely to be any intermediate outcomes … Directness also applies to comparing interventions and for both diagnostic accuracy and intervention

154. Disposition of Comments Report for Core Needle and Open Surgical Biopsy for Diagnosis of Breast Lesions: An Update to the 2009 Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_disposition-comments.pdf
     September 10, 2014 - We have used the term “in the diagnostic assessment”. … Diagnostic yield is defined variably by different authors. … Methods Are the definitions or diagnostic criteria for the outcome measures appropriate? … and diagnostic test categories (including false positives) in the revised report. … Repeat biopsies may be required because the results of the first biopsy were non-diagnostic.

155. Hypertension-Pulmonary-Arterial Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/hypertension-pulmonary-arterial_research-protocol.pdf
     January 30, 2013 - Diagnostic accuracy efficacy (sensitivity, specificity, positive predictive value/negative predictive … Diagnostic thinking efficacy and therapeutic efficacy (clinician judgment about diagnosis/prognosis, … Analytic Framework(s) Patients at high risk for PAH Patients with suspected PAH Diagnostic accuracy … The efficacy of diagnostic imaging. … QUADAS-2: A Revised Tool for the Quality Assessment of Diagnostic Accuracy Studies.

156. Disposition of Comments Report for Imaging Techniques for Treatment Evaluation for Metastatic Breast Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-imaging_disposition-comments.pdf
     October 01, 2014 - It is possible that these patients would be better managed by FDG PET (without diagnostic CT) or by … within the delivery of healthcare, diagnostic imaging’s value outside the care paradigm would be of … Models that attempt to extract diagnostic imaging from the care that it informs neglect to reflect the … General Comments (continued) A more appropriate endpoint for diagnostic imaging would be similar … to that which AHRQ considers as “intermediate outcomes” including effects on diagnostic thinking and

157. Stroke Prevention in Atr ial Fibr illation Patients: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-afib-update_research-protocol-amended.pdf
     October 27, 2017 - accuracy efficacy o Diagnostic thinking efficacy (defined as how using diagnostic technologies help … We will pay particular attention to describing the details of the diagnostic tools (e.g., instrument … For studies assessing diagnostic accuracy, we will use the Quality Assessment of Diagnostic Accuracy … QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies. … Grading quality of evidence and strength of recommendations for diagnostic tests and strategies.

158. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea_research-protocol.pdf
     March 15, 2010 - in-laboratory polysomnography is costly, resource intensive, and burdensome to the patient, other diagnostic … Oximetry can be diagnostic of OSA. Pulse oximetry will be evaluated among the diagnostic tests. … What is the correlation between the choice of initial diagnostic test to determine the diagnosis of … General symptom scales (e.g., diagnostic screening questionnaires); only validated measures d. … For questions regarding comparisons of diagnostic tests (KQ1−2), we will consider using Bland-Altman

159. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0320_06-17-2009.pdf
     January 01, 2009 - Outcome(s): Comparative diagnostic, prognostic, and therapeutic accuracy; cost savings (e.g., decreased … Is there improved diagnostic and/or therapeutic accuracy for FLC analysis in conjunction with serum … What is the diagnostic and/or therapeutic monitoring utility of the К/λ ratio? 4.

160. Prognostic Tests (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-prognostic.ppt
     June 01, 2012 - Statistical evaluation of prognostic versus diagnostic models: beyond the ROC curve. … Comparisons of predictive values of binary medical diagnostic tests for paired designs. … Reviewers can adapt criteria developed for diagnostic tests. … Statistical evaluation of prognostic versus diagnostic models: beyond the ROC curve. … Comparisons of predictive values of binary medical diagnostic tests for paired designs.