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201. Modeling to evaluate benefits and harms of new diagnostic tests compared to established diagnostic tests – uses and limitations (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/benefits-harms-modeling_research.pdf
     November 19, 2009 - considering improvements in accuracy, as well as potential shifts in the disease spectrum for positive diagnoses … For example, in colon cancer diagnosis, both capsule endoscopy (index test) and colonoscopy (reference … not necessarily undesirable as long as there are no changes in the disease spectrum for the positive diagnoses … Home diagnosis of obstructive sleep apnea-hypopnea syndrome. … Diagnostic test accuracy may vary with prevalence: implications for evidence- based diagnosis.

202. Breast-Abnormalities-Tests-Update Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-abnormalities-tests-update_research-protocol.pdf
     July 01, 2010 - Survival rates depend on the stage of disease at diagnosis. … In other words, these studies are not intended to provide a final diagnosis as to the nature of the … The study must have enrolled patients referred for the purpose of primary diagnosis of a breast abnormality … Keywords included in the search strategy encompass the concepts of breast cancer, diagnosis, noninvasive … However, women who experience a false- negative error may die as the result of a delayed cancer diagnosis

203. Insomnia_protocol-140403 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/insomnia_protocol-140716.pdf
     April 03, 2014 - Additionally, the diagnosis requires that symptoms not be better explained by other sleep disorders … For treatments to be effective, an accurate diagnosis must first be made. … Study inclusion criteria Category Criteria for Inclusion Study • adults with diagnoses consistent … of adults: older adults adultswith insomnia disorder and coexisting medical or mental health diagnoses … Clinical diagnosis and misdiagnosis of sleep disorders.

204. breast-biopsy-update-130920 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-biopsy-update_research-protocol.pdf
     September 20, 2013 - Practice Center Systematic Review Protocol Project Title: Core Needle and Open Surgical Biopsy for Diagnosis … develop breast cancer during their lifetime, and an estimated 2.7 million women had a current or past diagnosis … The process of breast cancer diagnosis is initiated by detection of an abnormality through self-examination … test performance of different types of core-needle breast biopsy when compared with open biopsy for diagnosis … illustrates how core-needle biopsy versus open surgical biopsy may result in KQ 1 outcomes such as diagnosis

205. Fractional Exhaled Nitric Oxide Clinical Utility in Asthma Management (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-nitric-oxide_research-protocol.pdf
     September 06, 2016 - For example, in 2012, asthma was one of the top twenty leading diagnosis groups for primary care visits … However, the diagnosis remains clinical; there is no single gold standard diagnostic test. … The guidelines address the diagnosis, evaluation, and treatment of asthma. … Specifically, 1.a: What is the diagnostic accuracy of FeNO measurement(s) for making the diagnosis … Expert Panel Report 3 (EPR-3): Guidelines for the diagnosis and management of asthma.

206. Breast Abnormalities Update Surveillance Assessment_CER 47_Low (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-abnormalities-tests-update_surveillance.pdf
     September 01, 2012 - all/consecutive patients or not, whether the study was prospective in design or not, whether all diagnoses … differences; whether the studies blinded image readers to clinical information or not; whether all diagnoses … AND sensitivity and specificity"/ or early diagnosis/ or diagnostic imaging/ or diagnostic value/ or … all/consecutive patients or not, whether the study was prospective in design or not, whether all diagnoses … differences; whether the studies blinded image readers to clinical information or not; whether all diagnoses

207. Draft Comment Form for Diagnosis of Attention-Deficit/Hyperactivity Disorder in Adults | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/form/hyperactivity-disorder/draft-comments

208. Emerging Approaches to Diagnosis and Treatment of Non-Muscle-Invasive Bladder Cancer | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/bladder-cancer-non-muscle-invasive/research-protocol

209. Emerging Approaches to Diagnosis and Treatment of Non–Muscle-Invasive Bladder Cancer | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/bladder-cancer-non-muscle-invasive/research

210. Nonsurgical Treatments for Urinary Incontinence in Adult Women: Diagnosis and Comparative Effectiveness | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/urinary-incontinence-treatment/research

211. PCA3 Testing in the Diagnosis and Management of Prostate Cancer: Future Research Needs | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/prostate-cancer-antigen-3-gene/research

212. Pharmacologic and Nonpharmacologic Treatments of Post-Traumatic Stress Disorder (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-protocol.pdf
     July 10, 2018 - vocational, education); return to school/work; prevention or reduction of comorbid psychiatric or medical diagnoses … (DSM-III, DSM-IV, or DSM-5) Children (<18 years old) Diagnosis of acute stress disorder Studies … Census categories)* l. % with PTSD diagnosis m. … Comorbid diagnoses required for study entry n. % Treatment naïve* o. % with depression* p. % with … Proportion who achieved PTSD diagnostic change (loss of diagnosis), by condition l.

213. Pharmacologic and Nonpharmacologic Treatments of Post-Traumatic Stress Disorder (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ptsd-protocol.pdf
     July 10, 2018 - vocational, education); return to school/work; prevention or reduction of comorbid psychiatric or medical diagnoses … (DSM-III, DSM-IV, or DSM-5) Children (<18 years old) Diagnosis of acute stress disorder Studies … Census categories)* l. % with PTSD diagnosis m. … Comorbid diagnoses required for study entry n. % Treatment naïve* o. % with depression* p. % with … Proportion who achieved PTSD diagnostic change (loss of diagnosis), by condition l.

214. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0332_07-29-2010.pdf
     January 01, 2010 - testing or subsequent management options associated with use of the PCA3 assay for prostate cancer diagnosis … for social, economic, or psychological harm associated with use of PCA3 assay for prostate cancer diagnosis … critical need for an understanding of how this marker compares to current practices for screening, diagnosis

215. Breast-Biopsy Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy_surveillance.pdf
     July 01, 2012 - CER # 19: Comparative Effectiveness of Core Needle Biopsy and Open Surgical Biopsy for Diagnosis of … One expert felt this is only true for women who have a benign diagnosis. … Intraductal papillomas of the breast: Diagnosis and management of 151 patients. … underestimation rate, difference by guidance or needle type not statisically significant ND 40% of LCIS diagnoses … upgraded, 27% of ALH diagnoses upgraded - difference not statisically significant ND Londero,

216. Hypertension-Pulmonary-Arterial Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypertension-pulmonary-arterial_executive.pdf
     April 01, 2013 - was 2.8 years.1,4 Screening and Diagnosis There are two separate populations for which screening … The procedure-related mortality was 0.055 percent.5 RHC not only confirms the diagnosis of PAH but … Guidelines on diagnosis and treatment of pulmonary arterial hypertension. … Diagnosis and differential assessment of pulmonary arterial hypertension. … Guidelines for the diagnosis and treatment of pulmonary hypertension: the Task Force for the Diagnosis

217. Topic 0590 Strategies to Treat and Manage Infantile Hemangioma NSD FINAL_SJ (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0715-140408.pdf
     May 29, 2025 - computed tomography (CT), or ultrasound Comparator(s): No use of imaging Outcome(s): Accuracy of diagnosis … What is the comparative safety and effectiveness of imaging to that of no imaging in the diagnosis

218. AHRQ Slide Template-Widescreen
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-child-adolesc-mental-health-grand-rounds.pptx
     May 22, 2025 - Michelle Zabel, M.S.S. 3:35–3:50 Presentation of Diagnosis and Management of Obsessive Compulsive Disorders … ADHD Diagnosis and Treatment in Children and Adolescents Southern California Evidence-based Practice … Lauren Pilcher, Robyn Wheatley 9 Eligibility Criteria for Studies Reporting on clinical ADHD Diagnosis … when tool discriminates ADHD from typically developing youth Tools tend to generate false positive diagnoses … in youth who have diagnoses other than ADHD AUC Specificity Sensitivity 15 KQ1 Diagnosis Conclusions

219. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0311_06-17-2008.pdf
     January 01, 2008 - renal function impairment Intervention(s): Measurement of troponin levels Comparator(s): Clinical diagnosis … disease, a systematic review on this topic would have a significant impact by aiding clinicians in the diagnosis

220. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0404_01-14-2011.pdf
     January 01, 2011 - treprostinil and ambrisentan); combination therapies; use of testing (vasoreactivity, biomarkers) for diagnosis … What are the optimal testing strategies and modalities (vasoreactivity, biomarker) for guiding the diagnosis