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81. Screening for Prediabetes and Type 2 Diabetes in Children: Clinical Summary (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/UHEkFHhddYa3YXX6Mk-gac
    September 01, 2022 - and adolescents without symptoms of diabetes or prediabetes … distributed, as well as a family history of diabetes … • Treatment of type 2 diabetes and prediabetes generally includes lifestyle modifications (changes … • Type 2 diabetes affects approximately 23,000 children and adolescents in the US. … The incidence of type 2 diabetes is on the rise.

82. Ykjvkfmv5Jf8Bl3Rbx8Bp7 (pdf file)
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    December 01, 2015 - The harms of drug therapy for the prevention of diabetes are small to moderate, depending on the drug … More U.S. data are also needed on the benefits and harms of lifestyle interventions and medi- cal treatments … Lipid-lowering therapy seemed to be similarly ef- fective in RR reduction regardless of diabetes status … Effects of combination lipid therapy in type 2 diabetes mellitus. N Engl J Med. 2010;362:1563-74. … Efficacy of cholesterol-lowering therapy in 18,686 people with diabetes in 14 randomised trials of statins

83. Screening for Prediabetes and Type 2 Diabetes (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/t7xRPLdk_BnUBtBZBhtdHH
    April 12, 2021 - Type 2 diabetes, the most common form of diabetes, happens when the body doesn’t use insulin well and … Facts About Prediabetes and Type 2 Diabetes Diabetes is the seventh most common cause of death … Other risk factors include older age and family history of diabetes, gestational diabetes (diabetes … For those found to have diabetes through screening, earlier detection, diagnosis, and treatment can … ://www.niddk.nih.gov/health-information/diabetes/overview/what-is-diabetes/type-2-diabetes

84. Evidence Summary: Statins for Prevention of Cardiovascular Disease in Adults: Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: Preventive Medication | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-statins/statin-use-in-adults-preventive-medication
    November 13, 2016 - , and treatment strategies (eg, treat to target lipid levels vs fixed-dose statin therapy; choice of … general US primary care settings based on the characteristics of the patients enrolled, the statin therapies … treatment. … Pravastatin and the development of diabetes mellitus: evidence for a protective treatment effect in the … Statin therapy and risk of developing type 2 diabetes: a meta-analysis.

85. Archived: Evidence Summary: Statins for Prevention of Cardiovascular Disease in Adults: Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: Preventive Medication | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-statins/statin-use-in-adults-preventive-medication-november-2016
    November 13, 2016 - , and treatment strategies (eg, treat to target lipid levels vs fixed-dose statin therapy; choice of … general US primary care settings based on the characteristics of the patients enrolled, the statin therapies … treatment. … Pravastatin and the development of diabetes mellitus: evidence for a protective treatment effect in the … Statin therapy and risk of developing type 2 diabetes: a meta-analysis.

86. Aspirin for the Primary Prevention of Cardiovascular Events: A Systematic Evidence Review for the USPSTF (pdf file)
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    April 01, 2016 - Diabetes Available evidence does not clearly support the heterogeneity of aspirin's treatment effect … The 11 pri- mary prevention studies are heterogeneous in terms of aspirin dose; duration of therapy; … conclude that the cardiovascular-related benefits (that is, nonfatal MI) occur during the first 5 years of therapy … AHA/ACCF Secondary Prevention and Risk Reduction Therapy for Patients with Coronary and other Atherosclerotic … Primary and secondary prevention of cardiovascular disease: Anti- thrombotic Therapy and Prevention of

87. Archived: Final Evidence Summary: Obesity in Adults: Screening and Management | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary38/obesity-in-adults-screening-and-management-2012
    October 15, 2011 - Weight-loss treatment reduced diabetes incidence in participants with prediabetes. … Role of orlistat in the treatment of obese patients with type 2 diabetes. … Impact of intensive lifestyle and metformin therapy on cardiovascular disease risk factors in the diabetes … Clinical efficacy of orlistat therapy in overweight and obese patients with insulin-treated type 2 diabetes … Behavioral and pharmacologic therapies for obesity. Nat Rev Endocrinol . 2010;6:578-88.

88. Recommendation: Peripheral Artery Disease and Cardiovascular Disease: Screening and Risk Assessment With the Ankle-Brachial Index | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/recommendation/peripheral-artery-disease-in-adults-screening-with-the-ankle-brachial-index
    July 10, 2018 - Treatments and Interventions Treatment of PAD has 2 potential targets: reducing morbidity and mortality … The harms of preventive treatment for PAD or CVD include bleeding (with aspirin use) and possibly diabetes … PAD are also used to calculate CVD risk, patients with a low ABI may already be recommended for these treatments … Four studies, 2 of aspirin therapy and 2 of exercise therapy, addressed treatment of asymptomatic patients … signs or symptoms of CVD or PAD but would still be subjected to the harms of testing and subsequent treatments

89. Screening for Prediabetes and Type 2 Diabetes in Children and Adolescents: Evidence Report and Systematic Review (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/U8LgX3tsN9LEF5JnsNbSc_
    September 13, 2022 - Of those, 6 were from the Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) study … Safety and tolerability of the treatment of youth-onset type 2 diabetes: the TODAY experience. … Treatment options for type 2 diabetes in adolescents and youth: a study of the comparative efficacy … Kelsey MM, Geffner ME, Guandalini C, et al; Treatment Options for Type 2 Diabetes in Adolescents and … Presentation and effectiveness of early treatment of type 2 diabetes in youth: lessons from the TODAY

90. Screening for Abnormal Blood Glucose and Type 2 Diabetes Mellitus: Clinical Summary (pdf file)
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    April 04, 2019 - Screening for Abnormal Blood Glucose and Type 2 Diabetes Mellitus: Clinical Summary Screening … for Abnormal Blood Glucose and Type 2 Diabetes Mellitus: Clinical Summary Population Adults aged 40 … Diagnosis of IFG, IGT, or type 2 diabetes should be confirmed with repeated testing (the same test on … Treatment and Interventions Effective behavioral interventions combine counseling on a healthful diet … Balance of Benefits and Harms The overall benefit of screening for IFG, IGT, and diabetes and implementing

91. Draft Research Plan: Chronic Kidney Disease: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/chronic-kidney-disease-screening
    January 19, 2023 - whether patients have screen- or non-screen-detected CKD, or whether patients are eligible for evaluated treatments … for reasons other than CKD (e.g., presence of diabetes mellitus, hypertension, or dyslipidemia). … stages 1–3 (based on 2012 KDIGO or 2002 KDOQI definitions * or equivalent), including adults with diabetes … Sodium-glucose cotransporter-2 inhibitors Glucagon-like peptide-1 agonist Statins Screening tests and treatments … vs. placebo, usual care, or no treatment More intensive vs. less intensive treatment (management of

92. Evidence Summary: Vitamin D Deficiency: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary18/vitamin-d-deficiency-screening
    November 25, 2014 - Two commonly available vitamin D treatments (vitamin D 3 [cholecalciferol] and vitamin D 2 [ergocalciferol … Diabetes Care . 2010;33:2021-3. [PMID: 20805275] 25. … Diabetes . 2011;60:2748-57. [PMID: 21911741] 73. … Diabetes Care . 2008;31:701-7. [PMID: 18235052] 88. … Histomorphometric effects of calcium or calcium plus 25-hydroxyvitamin D 3 therapy in senile osteoporosis

93. Archived: Evidence Summary: Vitamin D Deficiency: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary18/vitamin-d-deficiency-screening-november-2014
    November 25, 2014 - Two commonly available vitamin D treatments (vitamin D 3 [cholecalciferol] and vitamin D 2 [ergocalciferol … Diabetes Care . 2010;33:2021-3. [PMID: 20805275] 25. … Diabetes . 2011;60:2748-57. [PMID: 21911741] 73. … Diabetes Care . 2008;31:701-7. [PMID: 18235052] 88. … Histomorphometric effects of calcium or calcium plus 25-hydroxyvitamin D 3 therapy in senile osteoporosis

94. Screening for Prediabetes and Type 2 Diabetes: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/h8qcZeQ68AQPS9DemArgXX
    July 13, 2021 - now considered to be current standard medical therapy. … Saxagliptin as initial therapy in treatment-naive Indian adults with type 2 diabetes mellitus inadequately … Impact of intensive lifestyle and metformin therapy on cardiovascular disease risk factors in the diabetes … Low-dose combination therapy with rosiglitazone and metformin to prevent type 2 diabetes mellitus … Long-term effects of intensive multifactorial therapy in individuals with screen-detected type 2 diabetes

95. Final Research Plan: Celiac Disease: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan99/celiac-disease-screening
    November 03, 2014 - A subsequent branch from persons with abnormal test results leads to treatment, and an arrow from treatment … life compared with no treatment? … Studies of asymptomatic patients at higher risk (including patients with type 1 diabetes) will be included … Studies of asymptomatic patients at higher risk (including patients with type 1 diabetes) will be included … Studies of asymptomatic patients at higher risk (including patients with type 1 diabetes) will be included

96. Archived: Asymptomatic Bacteriuria in Adults: Screening, 1996 | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/recommendation/asymptomatic-bacteriuria-adults-screening-1996
    January 01, 1996 - National Diabetes Data Group. Diabetes in America: diabetes data compiled. 1984. … Therapy vs. no therapy for bacteriuria in elderly ambulatory nonhospitalized women. … Prospective, randomized comparison of therapy and no therapy for asymptomatic bacteriuria in institutionalized … The treatment of urinary tract infections in women with diabetes mellitus. … Controlled trial of therapy in covert bacteriuria in childhood.

97. Screening for Peripheral Artery Disease and Cardiovascular Disease Risk Assessment With the Ankle-Brachial Index: US Preventive Services Task Force Recommendation Statement (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/acqA29t-vpgphFscNPEfG8
    January 01, 2020 - The harms of preventive treatment for PAD or CVD include bleeding (with aspi- rin use) and possibly diabetes … Treatments and Interventions Treatment of PAD has 2 potential targets: reducing morbidity and mortality … PAD are also used to calculate CVD risk, patients with a low ABI may already be recommended for these treatments … Four studies, 2 of aspirin therapy and 2 of exercise therapy, ad- dressed treatment of asymptomatic patients … signs or symptoms of CVD or PAD but would still be subjected to the harms of testing and subsequent treatments

98. Archived: Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: Preventive Medication | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/recommendation/statin-use-in-adults-preventive-medication-november-2016
    November 13, 2016 - vs no treatment, or delayed vs earlier treatment in adults in this age group. … to "which population should be prescribed statin therapy?" … The treatment strategy is treatment-to-target rather than by therapy dose (eg, ≥50% reduction in LDL-C … Cholesterol Treatment Trialists’ (CTT) Collaborators. … Cardiovascular benefits and diabetes risks of statin therapy in primary prevention: an analysis from

99. Evidence Summary: Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: Preventive Medication | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/statin-use-in-adults-preventive-medication
    August 23, 2022 - Statin therapy was not significantly associated with increased diabetes risk overall (RR, 1.04 [95% CI … group, high crossover from usual care, and increased use of nonstatin therapies in the usual care group … CVD events were prevented with no incident diabetes cases. 42 No study directly compared treatment … Pravastatin and the development of diabetes mellitus: evidence for a protective treatment effect in the … Statin therapy: diabetes mellitus risk and cardiovascular benefit in primary prevention.

100. 3Srxnwxgcldkb Bpt2Cqwf (pdf file)
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     May 23, 2019 - an incremental benefit compared with initiating treatment after clinical diagnosis. … individual risk for coronary heart disease, which is an integral part of decisions about lipid-lowering therapy … The third report of the Adult Treatment Panel III of the National Cholesterol Education Program recommends … Counseling to Promote a Healthy Diet,” “Counseling to Promote Physi- cal Activity,” and “Screening and Treatment … Screening for diabetes. American Diabetes Association. Diabetes Care. 2002; 25:S21-S24. 2.