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161. Final Research Plan: Hormone Therapy in Postmenopausal Persons: Primary Prevention of Chronic Conditions | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/menopausal-hormone-therapy-preventive-medication
     May 27, 2021 - Localized (nonsystemic) treatments such as rings, creams, or gels; contraceptives; other hormones; treatments … of menopausal symptoms such as over-the-counter preparations or compounded bioidentical therapies that … life (if related to chronic conditions of interest) Functional capacity Urinary incontinence Diabetes … classified as chronic diseases: heart disease, cancer, chronic lung disease, stroke, Alzheimer’s disease, diabetes … , progesterone only therapy, androgen therapy, and testosterone therapy; nonsystemic treatments are not

162. Final Research Plan: Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: Preventive Medication | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan98/statin-use-in-adults-preventive-medication
     May 02, 2014 - (e.g., statins) and lifestyle interventions (e.g., exercise and diet changes) Other types of treatments … (e.g., myopathy, rhabdomyolysis, myalgia, cognitive loss, diabetes, elevations in liver function tests … or usual care without statin KQ 2: Placebo KQ 3: Higher vs. lower-potency statin therapy … : Side effects from drug interventions, such as myopathy, rhabdomyolysis, myalgia, cognitive loss, diabetes … In response to public comments, a key question on how benefits and harms vary according to statin therapy

163. Archived: Final Research Plan: Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: Preventive Medication | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan98/statin-use-in-adults-preventive-medication-november-2016
     May 02, 2014 - (e.g., statins) and lifestyle interventions (e.g., exercise and diet changes) Other types of treatments … (e.g., myopathy, rhabdomyolysis, myalgia, cognitive loss, diabetes, elevations in liver function tests … or usual care without statin KQ 2: Placebo KQ 3: Higher vs. lower-potency statin therapy … : Side effects from drug interventions, such as myopathy, rhabdomyolysis, myalgia, cognitive loss, diabetes … In response to public comments, a key question on how benefits and harms vary according to statin therapy

164. Final Recommendation Statement: Asymptomatic Bacteriuria in Adults: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/asymptomatic-bacteriuria-in-adults-screening
     September 24, 2019 - or Interventions Pregnant persons with asymptomatic bacteriuria usually receive antibiotic therapy … was insufficient evidence to recommend for or against screening in older adult women or women with diabetes … One study included women aged 20 to 65 years without diabetes, 1 study included only women with diabetes … Therapy vs no therapy for bacteriuria in elderly ambulatory nonhospitalized women. … Harding GK, Zhanel GG, Nicolle LE, Cheang M; Manitoba Diabetes Urinary Tract Infection Study Group.

165. Screening and Interventions for Overweight in Children and Adolescents: Recommendation Statement (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/J-vUTejXWsdp_d86zK4Gth
     July 01, 2005 - Approximately 15% of children and adolescents aged 6 to 19 years are overweight and are at risk for diabetes … These conditions, which are often asymptomatic, increase the long-term risk for developing diabetes … Diabetes. 2002;51(1):204-209. 24. Sinaiko AR, Donahue RP, Jacobs DR Jr, Prineas RJ. … Behavioral therapy in the treatment of pediatric obesity. … Behavior therapy and sibutramine for the treatment of adolescent obesity: a randomized controlled trial

166. Archived: Obesity in Children and Adolescents: Screening, July 2005 | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/obesity-in-children-and-adolescents-screening-2005
     July 11, 2005 - Medical conditions new to this age group, such as type 2 diabetes mellitus, represent "adult" morbidities … These conditions, which are often asymptomatic, increase the long-term risk for developing diabetes and … Diabetes 2002;51(1):204-9. 24. Sinaiko AR, Donahue RP, Jacobs DR Jr, Prineas RJ. … Behavioral therapy in the treatment of pediatric obesity. … Behavior therapy and sibutramine for the treatment of adolescent obesity: a randomized controlled trial

167. Evidence Summary: Aspirin Use to Prevent Cardiovascular Disease: Preventive Medication | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/aspirin-to-prevent-cardiovascular-disease-preventive-medication
     April 26, 2022 - Cardiovascular disease (CVD) is the leading cause of death in the US. 1 Aspirin has long been a recommended therapy … Optimal Treatment (HOT) study. … Low-dose aspirin therapy in patients with type 2 diabetes and reduced glomerular filtration rate: subanalysis … Aspirin treatment and risk of first incident cardiovascular diseases in patients with type 2 diabetes … Annual risk of major bleeding among persons without cardiovascular disease not receiving antiplatelet therapy

168. 12th Annual Report to Congress on High-Priority Evidence Gaps for Clinical Preventive Services (pdf file)
     www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/inline-files/2022-annual-report-to-congress.pdf
     January 01, 2022 - Evaluate data on the effects of lifestyle interventions and medical treatments for screen- detected prediabetes … lifestyle interventions, pharmacotherapy, or both for treatment of screen-detected prediabetes and … interventions and medical treatments for screen-detected prediabetes and diabetes on health outcomes … • Evaluate data on the effects of lifestyle interventions and medical treatments for screen-detected … Cardiovascular Disease Counseling to Promote a Healthy Lifestyle in Adults Without CVD Risk Factors Hormone Therapy

169. Archived: Hormone Therapy in Postmenopausal Women: Primary Prevention of Chronic Conditions | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/menopausal-hormone-therapy-preventive-medication-december-2017
     December 12, 2017 - Treatment and Intervention Menopausal hormone therapy refers to the use of combined estrogen and progestin … The use of hormone therapy, whether administered orally, transdermally, or locally for the treatment … (N=17,903) in women without diabetes or not receiving treatment for diabetes at baseline. … The Endocrine Society 40 also focuses primarily on the use of hormone therapy for the treatment of symptoms … Treatment of symptoms of the menopause: an Endocrine Society clinical practice guideline.

170. Archived: Obesity in Adults: Screening and Management | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/obesity-in-adults-screening-and-management-2012
     June 15, 2012 - Benefits of Detection and Early Intervention/Treatment The USPSTF found adequate evidence that intensive … Effectiveness of Detection and/or Treatment No new trials were identified that compared screening for … Both also recommend that weight-loss and weight-maintenance therapies should include a reduced-calorie … diet, increased physical activity, and behavioral therapy. … Effectiveness of primary care--relevant treatments for obesity in adults: a systematic evidence review

171. Recommendation: Vitamin D Deficiency in Adults: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/vitamin-d-deficiency-screening
     April 13, 2021 - have been associated with risk for fractures, falls, functional limitations, some types of cancer, diabetes … 31.2 ng/mL) on a variety of health outcomes, including all-cause mortality, fractures, incidence of diabetes … D and calcium and clinical fracture or hip fracture incidence. 32 Five RCTs reported on incident diabetes … Lancet Diabetes Endocrinol . 2017;5(12):986-1004. … Vitamin D 20,000 IU per week for five years does not prevent progression from prediabetes to diabetes

172. Screening for Vitamin D Deficiency in Adults: US Preventive Services Task Force Recommendation (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/4BpSYQnx9MYzmKJSWQxrbC
     April 13, 2021 - low vitamin D levels (as opposed to clinical risks such as low bone density), or incidence of type 2 diabetes … have been associated with risk for fractures, falls, functional limitations, some types of cancer, diabetes … A pooled analysis of the 5 trials (n = 3356) found no difference in the incidence of diabetes among partici … Lancet Diabetes Endocrinol. 2017;5(12):986-1004. doi:10.1016/S2213-8587(17) 30357-1 4. … Vitamin D 20,000 IU per week for five years does not prevent progression from prediabetes to diabetes

173. Clinical Summary: Screening for Peripheral Artery Disease and Cardiovascular Disease Risk Assessment With the Ankle-Brachial Index (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/weRnLDyDtmfaycFr9tAKgs
     July 03, 2018 - Grade: I (insufficient evidence) Risk Assessment Major risk factors for PAD include older age, diabetes … Treatments and Interventions Treatment of PAD has 2 potential targets: reducing morbidity and mortality … PAD treatment focuses on improving outcomes in symptomatic patients; interventions to prevent CVD events … include smoking cessation, low ering cholesterol levels, managing high blood pressure, and antiplatelet therapy

174. Archived: Vitamin D Deficiency: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/vitamin-d-deficiency-screening-november-2014
     November 24, 2014 - on cancer, type 2 diabetes mellitus, risk for death in community-dwelling adults, and risk for fractures … been reported to increase risk for fractures, falls, functional limitations, some types of cancer, diabetes … Few studies have evaluated associations with functional limitations, diabetes, or depression, but these … therapies or UVB exposure was excluded. … of vitamin D deficiency on risk for cancer or diabetes or physical or psychosocial functioning, but

175. Esa M. Davis, M.D., M.P.H. | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/about-uspstf/current-members/esa-m-davis-md-mph
     March 01, 2025 - understanding perinatal determinants of maternal obesity and associated adverse health outcomes and improving treatment … obesity and associated racial disparities, and related adverse health outcomes, such as gestational diabetes … She has conducted comparative effectiveness trials on screening strategies for gestational diabetes,

176. Recommendation: Pancreatic Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/pancreatic-cancer-screening
     August 06, 2019 - Other factors such as new-onset diabetes, preexisting diabetes, older age, cigarette smoking, obesity … Other factors such as new-onset diabetes, preexisting diabetes, older age, cigarette smoking, obesity … Research on better treatments for all stages of pancreatic cancer to improve long-term survival and decrease … the harms of treatment is needed. … complications in another patient. 14 In another study, 2 cases of postoperative fistula and 3 cases of diabetes

177. Screening for Asymptomatic Bacteriuria in Adults: US Preventive Services Task Force Recommendation Statement (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/3R9N4ojm9Sk7qk8ybD3LU6
     October 11, 2019 - or Interventions Pregnant persons with asymptomatic bacteriuria usually receive an- tibiotic therapy … was insufficient evidence to recommend for or against screening in older adult women or women with diabetes … One study included women aged 20 to 65 years without diabetes, 1 study included only women with diabetes … Therapy vs no therapy for bacteriuria in elderly ambulatory nonhospitalized women. … Harding GK, Zhanel GG, Nicolle LE, Cheang M; Manitoba Diabetes Urinary Tract Infection Study Group.

178. Final Research Plan: Lipid Disorders in Children and Adolescents: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan151/lipid-disorders-in-children-screening
     January 15, 2015 - A subsequent branch leads to treatment (medications, lifestyle modifications), and an arrow from treatment … selective screening strategy KQs 1–4: Genetic screening alone Cascade screening Treatments … lipid-lowering medications (e.g., adverse events, long-term safety, overtreatment) KQs 1, 5, 8: Diabetes … based on body mass index) KQs 1–4: Genetic screening alone Cascade screening Treatments … overtreatment) Lifestyle modifications (e.g., nutritional, psychosocial) KQs 1, 5, 8: Diabetes

179. Archived: Final Research Plan: Lipid Disorders in Children and Adolescents: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan151/lipid-disorders-in-children-screening-july-2016
     January 15, 2015 - A subsequent branch leads to treatment (medications, lifestyle modifications), and an arrow from treatment … selective screening strategy KQs 1–4: Genetic screening alone Cascade screening Treatments … lipid-lowering medications (e.g., adverse events, long-term safety, overtreatment) KQs 1, 5, 8: Diabetes … based on body mass index) KQs 1–4: Genetic screening alone Cascade screening Treatments … overtreatment) Lifestyle modifications (e.g., nutritional, psychosocial) KQs 1, 5, 8: Diabetes

180. Recommendation: Asymptomatic Bacteriuria in Adults: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/asymptomatic-bacteriuria-in-adults-screening
     September 24, 2019 - or Interventions Pregnant persons with asymptomatic bacteriuria usually receive antibiotic therapy … was insufficient evidence to recommend for or against screening in older adult women or women with diabetes … One study included women aged 20 to 65 years without diabetes, 1 study included only women with diabetes … Therapy vs no therapy for bacteriuria in elderly ambulatory nonhospitalized women. … Harding GK, Zhanel GG, Nicolle LE, Cheang M; Manitoba Diabetes Urinary Tract Infection Study Group.