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621. Newly Medicare-Eligible Elders: Data Points #12 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/medicare-utilization-seniors_research.pdf
     June 01, 2012 - chronic conditions: cancer, Alzheimer’s, chronic obstructive pulmonary disease (COPD), depression, diabetes … † 3.6 3.4 2.9 2.8 Alzheimer’s 3.5 1.0 1.4 0.3 COPD 12.0 9.4 6.2 2.5 Depression 12.4 9.3 6.9 4.1 Diabetes … of full duals have at least one of our target conditions of cancer, Alzheimer’s, COPD, depression, diabetes … Methodological issues in the use of administrative claims data to study surveillance after cancer treatment … Chronic Obstructive Pulmonary Disease 11,266 2,253 4,080 57,189 Depression 11,632 2,246 4,554 95,030 Diabetes

622. Phenylketonuria Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/phenylketonuria_executive.pdf
     February 01, 2012 - The treatment choice that is the basis of this review is whether to add pharmacologic therapy in the … form of BH4 or LNAAs to dietary therapy. … As noted, this report focuses on the use of adjuvant treatments for PKU and does not address dietary … controlled and nonadherent populations, and among different age groups, for both types of adjuvant therapies … Phenylketonuria: Dietary and therapeutic challenges. J Inherit Metab Dis. 2007 Apr;30(2):145-52.

623. Infectious Disease Including HIV/AIDS #09 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/09_infectiousdisease_potential_high_impact_june_2012.pdf
     January 01, 2012 - , screening and diagnostics, therapeutics, surgery, programs, and care delivery innovations that address … As the first class of new therapies for HCV treatment in 20 years and the first class of direct-acting … As the first class of new therapies for HCV-infection treatment in 20 years and the first class of … treatments would significantly shift treatment or management models. … therapy was five before treatment.

624. Disposition of Comments Report for Pressure Ulcer Risk Assessment and Prevention (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/pressure-ulcer-prevention_disposition-comments.pdf
     May 08, 2013 - that future studies of preventive interventions...clearly describe usual care and other comparison treatments … of pressure ulcers [11] stated that “medical nutrition therapy is imperative for the prevention and … treatment of pressure ulcers.” … Nutritional supplementation is a low-risk, non-prescription therapy for pressure ulcers. … page ES-4 "(SIPS) were requested from identified drug and device manufacturers of pressure ulcer treatments

625. final Fibromyalgia CER protocol_3-31-14 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/fibromyalgia_research-protocol.pdf
     April 03, 2014 - exercise program, cognitive behavioral therapy and pharmaceutical therapy when indicated.1,17 Complementary … o Active § Exercise: supervised or independent (aerobic, strength training, stretching, water/therapeutic … • Other therapies o Mind-body therapies: meditation, hypnosis, tai chi, visualization o Other … and implementation (treatment fidelity) for nonpharmacologic treatments. … Journal of Manipulative & Physiological Therapeutics. 2011 Sep;34(7):483-96. PMID 21875523. 19.

626. Work Plan for Methods Research on (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/study-design-classification_research.pdf
     December 01, 2010 - Challenges in systematic reviews of therapeutic devices and procedures. … Management of diabetes mellitus in children younger than 5 years of age. … The effects of psychological therapies under clinically representative conditions: a meta- analysis. … Education, knowledge and metabolic control in children with type 1 diabetes. … In head-to-head studies, outcomes of two or more different exposures (treatments) are assessed.

627. Disposition of Comments_Comparative Effectiveness Review No. 262_Pharmacotherapy for Adults With Alcohol Use Disorder in Outpatient Settings: Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-262-pharmacotherapy-alcohol-disposition-comments.pdf
     November 07, 2023 - challenge for other medical conditions such as hyperlipidemia and diabetes. … Public Comment #1 (NCHR) Introduction We agree with the AHRQ analysis of the data regarding treatments … whether benefits were attributable to disulfiram (beyond the benefits of additional counseling or therapeutic … whether benefits were attributable to disulfiram (beyond the benefits of additional counseling or therapeutic … this outcome under potential benefits because we want to look for evidence regarding whether the treatments

628. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children_executive.pdf
     February 01, 2012 - associated with a higher risk of weight gain, elevated lipid and prolactin levels, and development of type 2 diabetes … Food and Drug Administration (FDA) approved risperidone and aripiprazole for the treatment of irritability … The object is to help consumers, health care providers, and others in making informed choices among treatment … Effectiveness Reviews, the program supports systematic appraisals of existing scientific evidence regarding treatments … • Treatment naïve versus history of previous antipsychotics use?

629. Engaging Patients in Information Sharing and Data Collection: The Role of Patient-Powered Registries and Research Networks (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/stakeholders-engagement-others_white-paper.pdf
     September 01, 2013 - contributed clinical data to provide information on “real world” practice and the effectiveness of treatments … registries currently exist for a wide range of chronic or rare conditions, including many forms of cancer, diabetes … recruit patients for clinical trials to learn about a particular disease or condition; to develop therapeutics … PPRs have also added to disease and treatment knowledge. … • Research across conditions/concomitant treatments.

630. Cer-238-Cervical-Ripening-Appendix-E-2 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-238-cervical-ripening-appendix-e-2.xlsx
     January 01, 2017 - through the trial following an adverse fetal outcome, leading to exclusion of women with diet-controlled diabetes … through the trial following an adverse fetal outcome, leading to exclusion of women with diet-controlled diabetes … 0.34 to 1.28) Frequency of newborn complications requiring >3 day hospitalization: "unaffected by" OP therapy … admission: 31.58% (18/57) vs. 31.75% (20/63) RR 0.99 (95% CI 0.59 to 1.68) NR NR Reminder: all patients had diabetes … lactate (26 silicone, 20 latex), congenital condition (15 silicone, six latex), maternal gestational diabetes

631. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/heart-failure-natriuretic-peptide_research-protocol.pdf
     December 20, 2011 - or NT-pro-BNP test’s ability to predict morbidity and mortality in HF patients, as well as whether therapies … The review will examine whether therapies involving BNP and NT-proBNP improve outcomes in HF patients … risk of coronary artery disease (CAD), with CAD, other adults at risk of HF without documented HF (diabetes … For KQ6, we will also extract a description of treatment arms (usual care, guided therapy, other); … based on clinical judgment with regards to comparability of study populations, diagnostic standard, treatments

632. Untitled (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_surveillance.pdf
     December 01, 2015 - Information about these treatments were not assessed in this surveillance report. … Robert Gish, MD University of San Diego San Diego, CA Averell Sherker, MD National Institute of Diabetes … What is the comparative effectiveness of antiviral treatments in improving intermediate outcomes, … KQ 2a and b: What is the comparative effectiveness of antiviral treatments in improving intermediate … Triple therapy in treatment-experienced patients with HCV-cirrhosis in a multicentre cohort of the French

633. Untitled (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c_surveillance.pdf
     December 01, 2015 - Information about these treatments were not assessed in this surveillance report. … Robert Gish, MD University of San Diego San Diego, CA Averell Sherker, MD National Institute of Diabetes … What is the comparative effectiveness of antiviral treatments in improving intermediate outcomes, … KQ 2a and b: What is the comparative effectiveness of antiviral treatments in improving intermediate … Triple therapy in treatment-experienced patients with HCV-cirrhosis in a multicentre cohort of the French

634. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/preterm-birth-terbutaline-pump_executive.pdf
     September 01, 2011 - maintenance therapy to prevent subsequent episodes. … Effectiveness Reviews, the program supports systematic appraisals of existing scientific evidence regarding treatments … No clear first-line maintenance tocolytic therapy has yet emerged. … 1 13 No comparison group 2 22,23 Primary Tocolytic IV magnesium sulfate only 1 23 Treatments IV magnesium … nonsignificant differences between the SQ terbutaline pump and oral terbutaline in the incidence of gestational diabetes

635. Cancer-Pancreas Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-pancreas_research-protocol.pdf
     August 09, 2013 - percent.5 Risk factors for pancreatic cancer include tobacco use; a personal history of pancreatitis, diabetes … between these populations and burden of disease may be related to higher rates of cigarette smoking and diabetes … that some Stage III cases are borderline resectable and may be appropriate targets for neoadjuvant therapy … adenocarcinoma is fatal if untreated, so it is critical to choose the right imaging test and initiate therapy … Were the study results unaffected by intervening treatments or disease progression/regression?

636. Disposition of Comments for CER 195 Management of Uterine Fibroids (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-195-disposition-comments-uterine-fibroids.pdf
     December 14, 2017 - The review "does not cover preoperative or adjunctive treatments." … Public Reviewer (Allergen) Background The first US Phase III trial indicates that medical therapy … system, eye care, medical aesthetics, gastroenterology, urology, cardiovascular, and anti-infective therapeutic … between very different treatments. … In many conditions for where direct marketing to consumers is common (diabetes, back surgery, orthopedic

637. Crosscutting-Horizon-Scan-High-Impact-1312 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1312.pdf
     December 01, 2013 - new (and new uses of existing) pharmaceuticals, medical devices, diagnostic tests and procedures, therapeutic … purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices, procedures, treatments … , screening and diagnostics, therapeutics, surgery, programs, and care delivery innovations that address … intention is to enable tracking of medication adherence in patients with conditions such as tuberculosis, diabetes … Adherence to long-term therapies.

638. Effects of Dietary Sodium and Potassium Intake on Chronic Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/sodium-potassium_research-protocol.pdf
     April 18, 2017 - Among subpopulations defined by hypertension, diabetes, and obesity health status. 2. … Among subpopulations defined by hypertension, diabetes, and obesity health status. 3. … Among subpopulations defined by hypertension, diabetes, and obesity health status. 7. … Blood pressure lowering in type 2 diabetes: a systematic review and meta-analysis. … PTCA, CVD mortality, total mortality) Adjustment factors for observational studies e.g., clinic, treatment

639. Continuous-Outcomes-Quantitative-Synthesis Methods (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/continuous-outcomes-quantitative-synthesis_methods.pdf
     March 01, 2011 - For example, in a study evaluating glycemic control in patients with type 2 diabetes, 4 patients … Statistical methods for analysis of effects of treatment in overviews of randomized trials. … Long- Acting Beta2-Agonist and Inhaled Corticosteroid Combination Therapy for Adult Persistent Asthma … Effectiveness in All Ages; and Variability in Prevalence, Diagnosis, and Treatment. … Meta-analysis: effect of monotherapy and combination therapy with inhibitors of the renin angiotensin

640. Alcohol-Misuse Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse_research-protocol.pdf
     April 28, 2010 - they represent about one-fifth of patients seen, a proportion similar to the proportions seen for diabetes … include the following: Motivational interviews of varying length and number Cognitive behavioral therapy … intended primarily to reduce alcohol intake (e.g., motivational interviews, cognitive behavioral therapy … with a KQ, we plan to summarize the available evidence regarding such treatments in the Introduction … Center for Substance Abuse Treatment.