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61. Evidence gaps for mHealth tools in diabetes | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/get-involved/nominated-topics/evidence-gaps-for-mhealth-tools-in-diabetes
    May 10, 2016 - Briefly describe a specific question, or set of related questions, about a health care test or treatment … Evidence gaps for mHealth tools in diabetes Describe why this topic is important. … products are being developed and promoted to payers, clinicians and patients to prevent or improve diabetes … for mHealth products that could lead to their use over in-person services shown to provide value in diabetes … tell us how you heard about the Effective Health Care Program Mobile Health Technology for Diabetes

62. Data Points #18: Use of and access to health care by Medicare beneficiaries with diabetes: impact of diabetes type and insulin use, 2007-2011 | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/diabetes-medicare-use/research
    January 29, 2014 - Diabetes is divided into two categories: type 1 (also known as juvenile diabetes) and type 2 (also known … as adult-onset diabetes). … However, complications such as these can be prevented with proper treatment and maintenance. … High-quality diabetes care is important to maintain the health and stability of people with diabetes. … Care for diabetes is becoming even more important with the increasing prevalence of diabetes in the United

63. Effectiveness of Treatments for Diabetic Peripheral Neuropathy | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/diabetic-neuropathy/research-protocol/

64. Data Points #3: Economic burden of diabetic foot ulcers and amputations | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/diabetes-foot-ulcer-amputation-economics/research
    March 08, 2011 - ulceration and those who require LEA, questions remain as to whether interventions such as hyperbaric oxygen therapy … , negative pressure wound therapy, and specialized dressing materials are really beneficial. … Since treatments are changing rapidly, especially for type 2 diabetes (the most common type of diabetes … in the Medicare population), it can be difficult for clinicians to keep track of the most useful therapies … This is related, in part, to the fact that there is relatively little standardized data on the treatment

65. Behavioral Programs for Diabetes Mellitus (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/diabetes-behavior-programs_executive.pdf
    September 11, 2015 - Care and Self Management The mainstay of treatment for T1DM is lifelong insulin therapy. … Interaction between diabetes and anxiety and depression: implications for treatment. … The effect of intensive treatment of diabetes on the development and progression of long-term complications … Association between 7 years of intensive treatment of type 1 diabetes and long-term mortality. … Guidance for Industry: Diabetes Mellitus: Developing Drugs and Therapeutic Biologics for Treatment

66. Insulin Delivery and Glucose Monitoring Methods: Future Research Needs (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/insulin-blood-sugar_research.pdf
    August 01, 2015 - Also this type of RCT may not be feasible, particularly because persons may switch therapies over time … treatment. … Intensive diabetes treatment and cardiovascular disease in patients with type 1 diabetes. … treatment. … Intensive diabetes treatment and cardiovascular disease in patients with type 1 diabetes.

67. Who Uses Exenatide For Glucose Control in Diabetes Mellitus? A Retrospective Cohort Study of a New Therapy | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/diabetes-glucose-control/research
    August 04, 2010 - are continually in development to improve treatment of this challenging disease. … The therapeutic target is restoration of first phase insulin secretion via the "incretin effect" in which … Its place in among the array of treatments for diabetes is not yet established as trials are currently … Using propensity scores subclassification to estimate effects of longitudinal treatments: an example … of a new therapy.

68. Layout 1 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-insulin_executive.pdf
    September 01, 2008 - Insulin use has been suggested as a first-line therapy in patients with type 2 diabetes, either as an … Premixed insulin preparations are a therapeutic alternative to multiple insulin injections in a near- … important to review and evaluate the weight of evidence for the safety and effectiveness of these insulin therapies … Clinicians may be better able to choose the most effective therapy for their patients with diabetes if … options for the treatment of type 2 diabetes.

69. Obesity (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/10_obesity_potential_high_impact_2012-12-11.pdf
    January 01, 2012 - , screening and diagnostics, therapeutics, surgery, programs, and care delivery innovations that address … of obesity High 2. * EndoBarrier Endoluminal Sleeve for treatment of obesity and/or type 2 diabetes … New drug treatment options are needed for obese patients seeking medical therapy for weight loss. … Type 2 Diabetes  Key Facts: Bariatric surgery is the only treatment that has been demonstrated … of Obesity EndoBarrier Endoluminal Sleeve for Treatment of Obesity and/or Type 2 Diabetes Obesity

70. Effective Health Care (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0134_07-19-2009.pdf
    January 01, 2009 - Nomination Summary: The nominator is interested in the comparative effectiveness of various treatment … What are the comparative differences in HbA1c levels when comparing various treatment options including … , and insulin pump therapy with continuous glucose monitoring? … )  Despite the increase in knowledge about diabetes, new therapies, and technologies available … patients to be highly compliant with treatment, including moving pump insertion locations and maintaining

71. mHealth for Diabetes (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0855-170515.pdf
    April 28, 2017 - type 2) compared with conventional treatments? … Diabetes technology & therapeutics. Nov 2012;14(11):1060-1067. 29. Katalenich BS, L. Liu, S. … Evaluation of a Remote Monitoring System for Diabetes Control. Clinical therapeutics. … Diabetes technology & therapeutics. May 2015;17(5):349-354. 31. Nicolucci AC, S. Chiriatti, A. … Diabetes technology & therapeutics. Aug 2015;17(8):563-570.

72. mHealth for Diabetes (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/tnd-0855-170515.pdf
    April 28, 2017 - type 2) compared with conventional treatments? … Diabetes technology & therapeutics. Nov 2012;14(11):1060-1067. 29. Katalenich BS, L. Liu, S. … Evaluation of a Remote Monitoring System for Diabetes Control. Clinical therapeutics. … Diabetes technology & therapeutics. May 2015;17(5):349-354. 31. Nicolucci AC, S. Chiriatti, A. … Diabetes technology & therapeutics. Aug 2015;17(8):563-570.

73. Depression-Chronic-Conditions-Interventions Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-chronic-conditions-interventions_executive.pdf
    August 01, 2012 - Effectiveness Reviews, the program supports systematic appraisals of existing scientific evidence regarding treatments … algorithm; patient preference for treatment: antidepressants or problem-solving therapy (6–8 sessions … area is personality disorders, which are pervasive by nature and can prove a barrier to achieving therapeutic … Effects of enhanced depression treatment on diabetes self-care. … Cost-effectiveness of systematic depression treatment among people with diabetes mellitus.

74. TND-0775-150722 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0775-150722.pdf
    May 12, 2015 - Comparator(s): Non-pharmacological treatments; all other treatment options/variations (e.g., different … to manage the side effects (e.g., weight gain, diabetes mellitus, extrapyramidal symptoms) of treatments … , electroconvulsive therapy). … Improvement Program [ATIP]), and somatic therapies such as electroconvulsive therapy, or transcranial … therapies can be high.

75. Diets | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/health-topics/diets
    August 14, 2013 - Comparative Effectiveness, Safety and Indications of Pre-mixed Insulin Analogues for Adults with Type 2 Diabetes … Systematic Review Archived September 15, 2008 Comparative Effectiveness of Treatment … Effectiveness Review and Meta-Analysis Systematic Review Archived June 10, 2013 Adjuvant Treatment

76. Obesity (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/10_obesity_potential_high_impact_june_2012.pdf
    January 01, 2012 - New drug treatment options are needed for obese patients seeking medical therapy for weight loss. … of Type 2 Diabetes  Key Facts: Bariatric surgery is the only treatment that has been demonstrated … mellitus [T2DM], and sleep apnea) may be candidates for drug therapy. 10,11 Drug therapy is typically … of Type 2 Diabetes Bariatric surgery is the only treatment that has been demonstrated to be effective … of Type 2 Diabetes Obesity Interventions Phentermine/Topiramate (Qnexa) for Treatment of Obesity

77. Comparative Effectiveness of Bariatric Surgery and Nonsurgical Therapy in Adults With Metabolic Conditions and a Body Mass Index of 30.0 to 34.9 kg/m² | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/weight-loss-surgery/research-protocol
    December 14, 2010 - 2013 Disposition of Comments Report Comparative Effectiveness of Bariatric Surgery and Nonsurgical Therapy … surgery such as LAGB and RYGB have been found to be far more effective than conventional nonsurgical therapy … contamination); the overall proportion of subjects lost to follow-up; important differences between treatments … The evidence of risks (adverse events) will be summarized for each surgical procedure and nonsurgical therapy … Adjustable gastric banding and conventional therapy for type 2 diabetes: a randomized controlled trial

78. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/insulin-blood-sugar-2010_research-protocol.pdf
    January 01, 2010 - in the United States. 3,4 Thus, a large segment of the population requires glucose-lowering therapies … so that therapeutic options can be selected that result in improved process, intermediate, and clinical … of individuals with diabetes who are receiving treatment in a usual care setting. … Intensive diabetes treatment and cardiovascular disease in patients with type 1 diabetes. … Continuous glucose monitoring and intensive treatment of type 1 diabetes.

79. Supplemental Project To Assess the Transparency of Reporting Requirements for Studies Evaluating the Effectiveness of Treatment Options for Symptoms of Diabetic Peripheral Neuropathy (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-neuropathy_research.pdf
    March 01, 2018 - Peer-reviewed publications were identified from an ongoing systematic review of treatments for diabetic … options (antidepressants, antiepileptics, and topical and subcutaneous treatments) to improve the … Gabapentin for the symptomatic treatment of painful neuropathy in patients with diabetes mellitus: … Prolonged-release oxycodone enhances the effects of existing gabapentin therapy in painful diabetic … Mexiletine in the treatment of diabetic neuropathy. Diabetes Care. 1992 Nov;15(11):1550-5.

80. Screening for and Management of Chronic Kidney Disease Stages 1-3 | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/kidney-disease-medicine/research-protocol
    July 28, 2010 - Third, CKD may be a marker for individuals less likely to receive proven medical therapies. … , 21 with therapeutic goals for these conditions sometimes set lower for CKD patients than for non-CKD … Treatments may be CKD-specific or non-specific. … treatments and kidney disease. … American Diabetes Association. Standards of medical care in diabetes-2009.