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521. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/heart-failure-natriuretic-peptide_research-protocol.pdf
     December 20, 2011 - or NT-pro-BNP test’s ability to predict morbidity and mortality in HF patients, as well as whether therapies … The review will examine whether therapies involving BNP and NT-proBNP improve outcomes in HF patients … risk of coronary artery disease (CAD), with CAD, other adults at risk of HF without documented HF (diabetes … For KQ6, we will also extract a description of treatment arms (usual care, guided therapy, other); … based on clinical judgment with regards to comparability of study populations, diagnostic standard, treatments

522. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children_executive.pdf
     February 01, 2012 - associated with a higher risk of weight gain, elevated lipid and prolactin levels, and development of type 2 diabetes … Food and Drug Administration (FDA) approved risperidone and aripiprazole for the treatment of irritability … The object is to help consumers, health care providers, and others in making informed choices among treatment … Effectiveness Reviews, the program supports systematic appraisals of existing scientific evidence regarding treatments … • Treatment naïve versus history of previous antipsychotics use?

523. Disposition of Comments for Quality Improvement Interventions To Address Health Disparities (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/disparities-quality-improvement_disposition-comments.pdf
     August 27, 2012 - the group (practice) were able to do this or, even more, how patients were able to pick their own treatments … there was randomization at the practice level, providers could break that randomization and select treatments … Not entirely sure what QI + [therapy] [meds] means, especially when the other construction uses -. … Meds are a form of therapy, so the distinction was lost on me. … We have replaced “QI+Therapy” and “QI+Meds” with “QI-Therapy” and “QI-Meds”.

524. Effects of Dietary Sodium and Potassium Intake on Chronic Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/sodium-potassium_research-protocol.pdf
     April 18, 2017 - Among subpopulations defined by hypertension, diabetes, and obesity health status. 2. … Among subpopulations defined by hypertension, diabetes, and obesity health status. 3. … Among subpopulations defined by hypertension, diabetes, and obesity health status. 7. … Blood pressure lowering in type 2 diabetes: a systematic review and meta-analysis. … PTCA, CVD mortality, total mortality) Adjustment factors for observational studies e.g., clinic, treatment

525. Cancer-Pancreas Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-pancreas_research-protocol.pdf
     August 09, 2013 - percent.5 Risk factors for pancreatic cancer include tobacco use; a personal history of pancreatitis, diabetes … between these populations and burden of disease may be related to higher rates of cigarette smoking and diabetes … that some Stage III cases are borderline resectable and may be appropriate targets for neoadjuvant therapy … adenocarcinoma is fatal if untreated, so it is critical to choose the right imaging test and initiate therapy … Were the study results unaffected by intervening treatments or disease progression/regression?

526. Microsoft Word - finbody.doc (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-artery-stenosis_research-2007.pdf
     January 01, 2007 - Analytic framework for evaluating the effectiveness and safety of treatments for renal artery stenosis … Stents were used only rarely and medical therapies varied both between and within studies. … were prospective, followed the natural history of 721 patients who mostly received various medical therapies … Including a third RCT with a substantial treatment crossover (medical therapy to angioplasty) at 3 months … , US Department of Health and Human Services/National Institutes of Health/National Institute of Diabetes

527. Disposition of Comments_Comparative Effectiveness Review No. 262_Pharmacotherapy for Adults With Alcohol Use Disorder in Outpatient Settings: Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-262-pharmacotherapy-alcohol-disposition-comments.pdf
     November 07, 2023 - challenge for other medical conditions such as hyperlipidemia and diabetes. … Public Comment #1 (NCHR) Introduction We agree with the AHRQ analysis of the data regarding treatments … whether benefits were attributable to disulfiram (beyond the benefits of additional counseling or therapeutic … whether benefits were attributable to disulfiram (beyond the benefits of additional counseling or therapeutic … this outcome under potential benefits because we want to look for evidence regarding whether the treatments

528. Engaging Patients in Information Sharing and Data Collection: The Role of Patient-Powered Registries and Research Networks (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/stakeholders-engagement-others_white-paper.pdf
     September 01, 2013 - contributed clinical data to provide information on “real world” practice and the effectiveness of treatments … registries currently exist for a wide range of chronic or rare conditions, including many forms of cancer, diabetes … recruit patients for clinical trials to learn about a particular disease or condition; to develop therapeutics … PPRs have also added to disease and treatment knowledge. … • Research across conditions/concomitant treatments.

529. Geographic Variation in Carotid Endarterectomy and Carotid Stenting Among Medicare Beneficiaries, 2003-2006 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cardiology-health-outcomes_research.pdf
     July 01, 2010 - Care Program Research Report Number 30 Introduction Carotid endarterectomy has been the recommended treatment … publication of several randomized studies in the 1990s comparing carotid endarterectomy with medical therapy … The overall rate of revascularization did not increase, even with the introduction of a new therapeutic … Ongoing clinical trials will provide critical guidance for the treatment of patients who are eligible … Carotid surgery versus medical therapy in asymptomatic carotid stenosis.

530. Continuous-Outcomes-Quantitative-Synthesis Methods (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/continuous-outcomes-quantitative-synthesis_methods.pdf
     March 01, 2011 - For example, in a study evaluating glycemic control in patients with type 2 diabetes, 4 patients … Statistical methods for analysis of effects of treatment in overviews of randomized trials. … Long- Acting Beta2-Agonist and Inhaled Corticosteroid Combination Therapy for Adult Persistent Asthma … Effectiveness in All Ages; and Variability in Prevalence, Diagnosis, and Treatment. … Meta-analysis: effect of monotherapy and combination therapy with inhibitors of the renin angiotensin

531. nnovative Methods in Stakeholder Engagement: An Environmental Scan (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/stakeholders-engagement-others_research-2012-1.pdf
     January 01, 2012 - about Innovative Methods in Stakeholder Engagement: An Environmental Scan 9 the effects of treatments … The JLA uses a sequence of steps to prioritize unanswered questions about treatments submitted by patients … Thus, DiabetesMine helped set the agenda in the diabetes device marketplace with a very small up-front … This allows them to capture physician insights into treatments, medications, and devices to inform … The James Lind Alliance: Tackling treatment uncertainties together.

532. FRN 30: Outpatient Case Management for Adults With Medical Illnesses and Complex Care Needs: Future Research Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/case-management-future_research.pdf
     June 01, 2015 - Patients with medical illness and complex care needs Quality of Care • Adherence to therapy • Missed … patients have more than one chronic condition or a complex condition that requires complex multiple treatments … Often the treatments and services needed are not integrated into a coherent system of care. … the recent Patients with medical illness and complex care needs Quality of Care • Adherence to therapy … studies that compare CM with different components such as factorial designs or studies with multiple treatment

533. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/preterm-birth-terbutaline-pump_disposition-comments.pdf
     September 01, 2011 - Peer Reviewer 1 KQ3 (Maternal Harms) The occurrence of gestational diabetes should be reported when … Likewise, “therapy discontinuation” is confusing. … Since we could not compare gestational diabetes between terbutaline by pump and other tocolytics from … that ought to be emphasized is the inclusion of pharmacokinetic and pharmacodynamic measures within treatment … treatment or no treatment shows low confidence that the evidence reflects a true effect”.

534. Phenylketonuria Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/phenylketonuria_executive.pdf
     February 01, 2012 - The treatment choice that is the basis of this review is whether to add pharmacologic therapy in the … form of BH4 or LNAAs to dietary therapy. … As noted, this report focuses on the use of adjuvant treatments for PKU and does not address dietary … controlled and nonadherent populations, and among different age groups, for both types of adjuvant therapies … Phenylketonuria: Dietary and therapeutic challenges. J Inherit Metab Dis. 2007 Apr;30(2):145-52.

535. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/preterm-birth-terbutaline-pump_executive.pdf
     September 01, 2011 - maintenance therapy to prevent subsequent episodes. … Effectiveness Reviews, the program supports systematic appraisals of existing scientific evidence regarding treatments … No clear first-line maintenance tocolytic therapy has yet emerged. … 1 13 No comparison group 2 22,23 Primary Tocolytic IV magnesium sulfate only 1 23 Treatments IV magnesium … nonsignificant differences between the SQ terbutaline pump and oral terbutaline in the incidence of gestational diabetes

536. final Fibromyalgia CER protocol_3-31-14 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/fibromyalgia_research-protocol.pdf
     April 03, 2014 - exercise program, cognitive behavioral therapy and pharmaceutical therapy when indicated.1,17 Complementary … o Active § Exercise: supervised or independent (aerobic, strength training, stretching, water/therapeutic … • Other therapies o Mind-body therapies: meditation, hypnosis, tai chi, visualization o Other … and implementation (treatment fidelity) for nonpharmacologic treatments. … Journal of Manipulative & Physiological Therapeutics. 2011 Sep;34(7):483-96. PMID 21875523. 19.

537. Infectious Disease Including HIV/AIDS #09 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/infectiousdisease_hi_impact.pdf
     December 01, 2013 - As the first class of new therapies for HCV treatment in 20 years and the first class of direct-acting … used only after other treatments fail … As the first class of new therapies for HCV-infection treatment in 20 years and the first class of … treatments would significantly shift treatment or management models. … therapy was five prior to treatment.

538. Disposition of Comments Report for Intravascular Diagnostic Procedures and Imaging Techniques Versus Angiography Alone in Coronary Artery Stenting (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/coronary-artery-stenting_disposition-comments.pdf
     February 26, 2013 - was compared with optimal medical therapy. … was compared with optimal medical therapy. … Treating low-risk lesions could lead to additional invasive tests or treatments that could adversely … of the rising costs of health care and continued focus on improved outcomes and appropriate use of therapies … Some of these characteristics include the percentage of patients with hypertension, diabetes, previous

539. Fleisher (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/fleisher.pdf
     January 01, 2010 - information overload • Although social support is an important component, content is also critical in treatment … PA_Nav_Net o Facebook Slide  26: Untitled Image of Pathways to Recovery  After Breast Cancer  Treatment

540. Untitled (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_surveillance.pdf
     December 01, 2015 - Information about these treatments were not assessed in this surveillance report. … Robert Gish, MD University of San Diego San Diego, CA Averell Sherker, MD National Institute of Diabetes … What is the comparative effectiveness of antiviral treatments in improving intermediate outcomes, … KQ 2a and b: What is the comparative effectiveness of antiviral treatments in improving intermediate … Triple therapy in treatment-experienced patients with HCV-cirrhosis in a multicentre cohort of the French