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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-outcomes_disposition-comments.pdf
    January 15, 2015 - measures chosen and how are they anchored in values for general medical populations (e.g. if rates of diabetes … both recognize the need for adjunctive therapy for many patients with SMI. … treatment. … Report Section Comment Response KI Reviewer #4 Findings With non-psychiatric disorders such as diabetes … Druss BG, Zhao L, Cummings JR, et al.: Mental comorbidity and quality of diabetes care under Medicaid
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stones-draft-appendi-c.xlsx
    January 01, 2024 - Prospective randomized evaluation of idiopathic hyperoxaluria treatments. … Prospective randomized evaluation of idiopathic hyperoxaluria treatments. … ED visit only: Selective therapy: 7% Empiric therapy: 7% Hospitalization only: Selective therapy: 2% … Empiric therapy: 2% Surgery only: Selective therapy: 8% Empiric therapy: 7% NR NR NR NR NR NR NR NR … Prospective randomized evaluation of idiopathic hyperoxaluria treatments.
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/restless-legs_disposition-comments.pdf
    November 27, 2012 - We agree but have included information based on information regarding recommended or considered therapies … mortality when their disease is not treated and it impacts co-morbid health conditions (hypertension, diabetes … unpredictable onset and severity of symptoms, daytime occurrence, and symptoms occurring outside the therapeutic … Polysomnography Data We feel sleep data would make a valuable contribution to the characterization of the therapeutic … effects of RLS treatments for Key Question 1.
  4. S103 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s103.pdf
    October 01, 2007 - an individual been sub- jected to both treatments. … Supported by a Centers for Education and Research on Therapeutics coop- erative agreement (3 U18 HS010548 … In many studies, including studies involving surgery and expensive one-time therapies, the majority of … Williams & Wilkins S105 hypertension, cardiovascular disease, chronic obstructive pul- monary disease, diabetes … Estimating causal effects of treatments in randomized and nonrandomized studies.
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/stakeholder-engagement_research.pdf
    September 01, 2011 - or treatment. … ; • Whether the new treatment is less invasive than existing treatments; • Patient preferences; • … Particle beam therapy (PBT) is a focused radiation therapy used to treat certain arteriovenous malformations … “Treating Type 2 Diabetes, The Oral Diabetes Drugs, comparing Effectiveness, Safety, and Price.” … Particle Beam Radiation Therapies for Cancer.
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/calcineurin-inhibitor_research-protocol.pdf
    October 08, 2014 - Alternatively, CNI use may be withdrawn or avoided entirely in favor of other immunosuppressant therapiesTherapeutic monitoring (KQ1a, KQ1b, KQ2). … monitoring of CNIs and CNI treatment strategies. … of patients receiving each specific ancillary treatment? … Were patients blinded to the treatment they received? 14.
  7. effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-applicability.ppt
    June 01, 2012 - clinician deciding on which diagnostic or prognostic tests to use for his or her frail, older patient with diabetes … Assessing Applicability (4 of 4) The third challenge arises because medical tests, even more so than treatments … The underlying prevalence of undiagnosed type 2 diabetes in pregnancy is increased. … in light of new therapeutics. … Important Contextual Factors (9 of 10) The sixth and final contextual factor to consider is changes in therapeutics
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-applicability.ppt
    June 01, 2012 - clinician deciding on which diagnostic or prognostic tests to use for his or her frail, older patient with diabetes … Assessing Applicability (4 of 4) The third challenge arises because medical tests, even more so than treatments … The underlying prevalence of undiagnosed type 2 diabetes in pregnancy is increased. … in light of new therapeutics. … Important Contextual Factors (9 of 10) The sixth and final contextual factor to consider is changes in therapeutics
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2024-surv-rep-update-table-e5.xlsx
    January 01, 2024 - Duration Measure (Mean, Median) Pain Duration, Months Psychiatric Comorbidity % N Interventions Dose Treatment … Long NR Ischemic heart disease, hypertension, heart failure, chronic obstructive pulmonary disease, diabetes … agent, cancer as underlying pain diagnosis, and history of cardiometabolic disease (e.g., hypertension, diabetes … B: Dronabinol as an add-on treatment Mean (SD) A: 16.6 (6.5) mg THC/15.4 (4.1) mg CBD/day B: 17.2 (7.6 … B: Long-acting opioid analgesics as an add-on treatment Mean (SD) A: 6.2 (2.4) sprays/day (16.74 mg
  10. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-update_executive.pdf
    December 01, 2011 - These second-generation treatments include selective serotonin reuptake inhibitors (SSRIs: citalopram … Effectiveness Reviews, the program supports systematic appraisals of existing scientific evidence regarding treatments … One trial showed that supplementing fluoxetine therapy with eszopiclone leads to improved sleep. … substance abuse, Alzheimer’s disease or other dementia, arthritis, cancer, coronary artery disease, diabetes … with the following comorbidities: alcohol/substance abuse, Alzheimer’s disease/dementia, arthritis, diabetes
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/measuring-blood-pressure_disposition-comments.pdf
    January 01, 2012 - Diabetes Technol Ther 2010;12:575-579. … title above the actual wording "appendix C" it cites "comparative effectiveness of the diagnosis and treatment … to “criteria” and added in parenthesis “(including populations, settings, interventions, control treatment … The emphasis on tailoring treatment to specific patient situations (avoiding overtreatment or undertreatment … Regarding the therapeutic targets for home BP we believe that this is still an area of uncertainty.
  12. S5 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s5.pdf
    October 01, 2007 - The aims are to maximize the likelihood that beneficial treatments are used and that harmful treatments … misclassification), random er- ror, confounding by clinical conditions, indications for drugs, or use of other therapies … Medicaid data for research on the initiation, continuation, and patient outcomes of prescription drug therapies … Risk-adjustment esti- mates can provide information on treatment benefits for patients who received treatment … using a new diabetes medication.
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine-update_research-protocol.pdf
    May 15, 2017 - Based on these findings, drug therapy may need to change at regular intervals until the treatment target … (progress from single therapy to combination therapy), (2) step down therapy (begin with combination … therapy and back down treatment when symptoms are under control), or (3) aggressively treat to target … to assess quantitatively whether the duration of disease in early RA modifies benefits or harms of treatments … Some examples of these uncertainties include the optimum order of therapeutics in early RA, and in patients
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children-update-disposition-170621.pdf
    March 16, 2017 - In particular how does weight gain or bmi relate to metabolic syndrome and risk for diabetes. … was limited data on many outcomes, but we were able to make some conclusions for some (incidence of diabetes … (e.g., tardive dyskinesias, diabetes). … The other two arms should be described as cognitive therapy + risperidone (n=43) and cognitive therapy … Throughout the report we only describe the arms that were included for this review; the supportive therapy
  15. effectivehealthcare.ahrq.gov/sites/default/files/antipsychotics-children-update-disposition-170621.pdf
    March 16, 2017 - In particular how does weight gain or bmi relate to metabolic syndrome and risk for diabetes. … was limited data on many outcomes, but we were able to make some conclusions for some (incidence of diabetes … (e.g., tardive dyskinesias, diabetes). … The other two arms should be described as cognitive therapy + risperidone (n=43) and cognitive therapy … Throughout the report we only describe the arms that were included for this review; the supportive therapy
  16. effectivehealthcare.ahrq.gov/sites/default/files/tx-for-localized-prostate-cancer_surveillanceassesment_20120614.pdf
    May 01, 2012 - It is not known whether these therapies are better or worse than other treatments for localized prostate … Diabetes and cardiovascular disease during androgen deprivation therapy: observational study of veterans … [ti] OR therapies[ti] OR treatment*[ti] OR treating[ti] OR treat[ti] OR therapy/mh AND Limits … Through 12/2005 Treatment with GnRH agonists was associated with increased risk of diabetes, coronary … It is not known whether these therapies are better or worse than other treatments for localized prostate
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/tx-for-localized-prostate-cancer_surveillanceassesment_20120614.pdf
    May 01, 2012 - It is not known whether these therapies are better or worse than other treatments for localized prostate … Diabetes and cardiovascular disease during androgen deprivation therapy: observational study of veterans … [ti] OR therapies[ti] OR treatment*[ti] OR treating[ti] OR treat[ti] OR therapy/mh AND Limits … Through 12/2005 Treatment with GnRH agonists was associated with increased risk of diabetes, coronary … It is not known whether these therapies are better or worse than other treatments for localized prostate
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/venous-ulcers-treatment_research-protocol.pdf
    September 13, 2012 - agents as opposed to drawing distinctions between individual therapeutic agents. … Comparisons will be made both within and across classes of therapies. … Antibiotic treatments for chronic venous ulcers Class Indications Drug names Benefits Disadvantages … Surgical treatments for chronic venous ulcers Pathology Treatment Superficial veins reflux Vein stripping … managing chronic wounds, including the application of case definitions for infection and initiating therapies
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-future-presentation-format_research.pdf
    January 01, 2019 - pseudorandom numbers to select 50 systematic reviews that included at least one meta-analysis of therapeutic … The probabilities of all 14 treatments at each willingness-to-pay threshold sum to 1. … in type 2 diabetes: systematic review and meta-analysis 2007 JAMA 19509383 Corticosteroids in the … Ann Intern Med 17237299 Pharmacological and lifestyle interventions to prevent or delay type 2 diabetes … Ann Intern Med 19620144 Systematic review: glucose control and cardiovascular disease in type 2 diabetes
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cystic-fibrosis-hgh_research-protocol.pdf
    August 22, 2008 - these measures show that patients with CF are at a disadvantage in terms of height and weight, and treatments … Adverse effects of interest include, but are not limited to: glucose intolerance, diabetes, and hypoglycemia … duration, baseline nutritional status, and concurrent medical therapies? … associated with rhGH use are also evaluated, including altered glucose metabolism, development of diabetes … (sex, age, ethnicity, nutritional status), co-morbidities, and use of concurrent standard medical therapies

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