-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/incident-user-design_research.pdf
May 01, 2012 - advantage of the incident user design is that it can capture the clinical consequences of an entire
therapeutic … and
risk of complications in patients with type 2
diabetes (UKPDS 33). … Adherence to prescribed antihypertensive
drug treatments: longitudinal study of
electronically compiled … Structural accelerated failure time models
for survival analysis in studies with time-
varying treatments … A review of uses
of health care utilization databases for
epidemiologic research on therapeutics.
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/dot-plots-methods.pdf
October 01, 2021 - ), revascularization, composite cardiovascular outcomes, withdrawal
due to adverse events, cancer, diabetes … 21313 2666 20491 0.99 0.94 1.04 0 High
Cancer 10 1181 27759 1174 27795 1.02 0.90 1.16 0.43 High
Diabetes … group
trt_N Total N of treatment group
ctrl_n Number of events in control group
ctrl_N Total N of … group
ctrl_bl_mean Weighted mean at baseline of treatment group
trt_N Total N of treatment group … Opioid Treatments for Chronic Pain.
-
effectivehealthcare.ahrq.gov/sites/default/files/s116.pdf
October 01, 2007 - RESULTS
The cohort consisted of 15,389 new users of APMs of
which 4905 initiated conventional APM therapy … However, if physicians who frequently pre-
scribe atypical APMs were using more hazardous treatments, … �80 10,750 70.0
History of
Cerebrovascular disease 4661 30.3
Congestive heart failure 4918 32.0
Diabetes … History of
Cerebrovascular disease 1.9 0.04 0.5 0.54
Congestive heart failure �1.2 0.22 �0.9 0.26
Diabetes … analysis and external adjustment for unmea-
sured confounders in epidemiologic database studies of therapeutics
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/glaucoma-screening_research-protocol.pdf
November 16, 2010 - at this asymptomatic or early stage
improves important health outcomes more than treatment once an … older age, and specific ocular or other medical conditions as defined by included studies (e.g.,
diabetes … Secondary outcome: We will also compare visual acuity outcomes (as measured by the Early
Treatment … In general, the figure illustrates how screening-based programs (which may
incorporate treatment when … Measures of treatment effect
We will calculate summary risk ratios or odds ratios as appropriate for
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/dental-jaw-rapid-response.pdf
May 01, 2025 - First, regarding “drug holidays” (i.e. pausing antiresorptive therapy before and after dental
treatments … Treatment strategies were outlined
for non-operative therapies and operative treatments in clinical … SIPMO-SICMF recognized use of systemic
antibiotic therapy in treatment of MRONJ-related infections and … Diabetes as a Risk
Factor for Medication-Related
Osteonecrosis of the Jaw. … Managing the Care of Patients
Receiving Antiresorptive Therapy for
Prevention and Treatment of Osteoporosis
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-supplements_surveillance.pdf
January 01, 2013 - Every
month since the CER’s original release, we received any FDA updates on the included
treatments … to
the conclusions involve refinement of original estimates or do the potential changes mean
some therapies … * adj3 herb$2) or
(therapeutic* adj3 plant$1) or (therapeutic* adj3 botanical*) or (plant$1 adj3 pharmacotherap … Inclusion criteria: diabetes
or hypercholesterolemia
under statin treatment, and
at least 1 of the … Vitamin K may improve the stability of anticoagulant
therapy.
-
effectivehealthcare.ahrq.gov/products/kidney-disease-medicine/research
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-future-research-steps-framework_research.pdf
June 01, 2011 - of treatments, etc. … and “How should physicians choose an
airway clearance therapy for a given patient with cystic fibrosis … Diabetes education for children with type 1
diabetes mellitus and their families. … of treatments, etc. … and “How should physicians
choose an airway clearance therapy for a given patient with cystic fibrosis
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cognitive-decline_executive.pdf
March 01, 2017 - Hormone
Therapy
Interventions
• Hormone therapy shows mixed results of harm and benefit.
• Low-strength … Antidementia
Treatments
• Low-strength evidence shows AChEI antidementia drugs did not reduce the incidence … Diabetes
Medication
Treatment
• No studies reported on the effect of diabetes treatment on the risk … • We found no relevant studies for depression treatments, smoking cessation, or community-level interventions … Moderate-strength
evidence showing no benefit for some antihypertensive
treatments and vitamin E for
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cognitive-decline_executive.pdf
March 01, 2017 - Hormone
Therapy
Interventions
• Hormone therapy shows mixed results of harm and benefit.
• Low-strength … Antidementia
Treatments
• Low-strength evidence shows AChEI antidementia drugs did not reduce the incidence … Diabetes
Medication
Treatment
• No studies reported on the effect of diabetes treatment on the risk … • We found no relevant studies for depression treatments, smoking cessation, or community-level interventions … Moderate-strength
evidence showing no benefit for some antihypertensive
treatments and vitamin E for
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/wireless-motility-capsule-future_research.pdf
May 01, 2013 - Often, standard medical
therapies have failed these patients. … Most patients with chronic constipation have improvement of symptoms with medical
therapy and/or lifestyle … Little data is available to support the timing of WMC in the diagnostic and therapeutic
approach to … Currently, symptoms and symptom resolution guide therapeutic decisions, but these require
careful interpretation … WMC in colonic dysmotility to predict outcomes, or to
predict the effects medical and/or surgical therapy
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/atrial-fibrillation_research-protocol.pdf
May 22, 2012 - clinical
factors (such as age, existence of congestive heart failure or left ventricular dysfunction,
diabetes … enlarged left atrium
Patients at high risk for stroke and bleeding events (e.g., patients with
diabetes … with an enlarged left atrium
o Patients at high risk for stroke and bleeding
events (patients with diabetes … Catheter ablation of atrial fibrillation in patients
with diabetes mellitus type 2: results from a randomized … clinical factors (such as age,
existence of congestive heart
failure or left ventricular
dysfunction, diabetes
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_5-user-guide-to-ocer_130129.pdf
January 01, 2012 - Alternative Treatments
Comparison of a treatment with a clinically
meaningful alternative treatment … and glitazones for diabetes, and are
not commonly used off-label for other conditions,
the indication … analysis and external
adjustment for unmeasured confounders in
epidemiologic database studies of therapeutics … Hormone
replacement therapy and cardiovascular health in
the United States. Med Care. … Cancer risk in patients with rheumatoid
arthritis treated with anti–tumor necrosis factor
a therapies
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoarthritis-knee-update_research-protocol.pdf
June 15, 2016 - (including self-initiated therapies), and treatment
duration or intensity? … (including self-initiated therapies),
and treatment duration or intensity? … o Physical treatments and/or weight loss
§ Physical therapy and exercise programs
• Manual therapy … Stem cell therapy trials will not have high applicability as this
treatment is currently limited in … Diagnostic and
Therapeutic Criteria Committee of the
American Rheumatism Association.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prioritization-selection-of-harms.pdf
February 01, 2018 - similar across
interventions used to treat a given condition (e.g., medications, non-pharmacological therapies … Rosiglitazone evaluated for cardiovascular
outcomes in oral agent combination therapy
for type 2 diabetes … Title
EPC, Year
Condition/ Population Harms Related Key Question(s) Interventions Harms Outcomes
Therapies … Dual agent therapy (statin
+ lipid modifying
medication) and
intensification of statin
therapy … Graded Exercise
Treatment;
pharmaceutical;
counseling/behavioral
therapy; complimentary
alternative
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children-update_research-protocol.pdf
December 04, 2015 - with antidepressants and other therapies, treatment is often augmented with
antipsychotics.26"
Substance … therapy?!!
!
!
! … therapy,!as!reported)_!medication!dose.!!
Comparators! Placebo/no!treatment,!any!other! … diabetes! New6onset!diabetes,!exacerbation!of!previous!diabetes,!diabetic!ketoacidosis,!
metabolic! … Indirect and mixed-treatment comparison, network, or multiple-treatments meta-
analysis: many names,
-
effectivehealthcare.ahrq.gov/sites/default/files/crosscutting_hi_impact.pdf
January 01, 2012 - new (and new uses of existing) pharmaceuticals, medical devices,
diagnostic tests and procedures, therapeutic … purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices,
procedures, treatments … , screening and diagnostics, therapeutics, surgery, programs, and care delivery
innovations that address … of chronic diseases requiring ongoing
medication such as tuberculosis, diabetes, heart failure, and … Adherence to long-term therapies.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ahrq-healthcare-horizon-scan-protocol-operations-manual-151001.pdf
September 01, 2015 - Potential to change current treatment models
ii. … The
MarketScan Treatment Pathways data analytics tool was used to estimate costs of existing
treatments … Process Off-Label
Use
Diabetes Technology &
Therapeutics
1, 4, 5, 7
Monthly journal that publishes … treatments. … Process Off-
Label
Uses
1 Advanced Technologies &
Treatments for Diabetes (ATTD)
1, 11
Annual
-
effectivehealthcare.ahrq.gov/sites/default/files/ahrq-healthcare-horizon-scan-protocol-operations-manual-151001.pdf
September 01, 2015 - Potential to change current treatment models
ii. … The
MarketScan Treatment Pathways data analytics tool was used to estimate costs of existing
treatments … Process Off-Label
Use
Diabetes Technology &
Therapeutics
1, 4, 5, 7
Monthly journal that publishes … treatments. … Process Off-
Label
Uses
1 Advanced Technologies &
Treatments for Diabetes (ATTD)
1, 11
Annual
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/bariatric-surgery-trends_research.pdf
November 01, 2012 - addition, studies have demonstrated significant improve-
ments in medical comorbidities such as type 2 diabetes … or
greater and at least one obesity-related
comorbidity who have documented unsuc-
cessful medical treatment … Reduction in incidence of diabetes, hyper-
tension and lipid disturbances after intentional weight loss … CMS decision memo for bariatric surgery for the treatment of morbid obesity
(CAG-00250R). 2006. … Case-matched outcomes in bariatric
surgery for treatment of type 2 diabetes in the morbidly obese patient