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1. Treatment Intensification in Type 2 Diabetes Mellitus | Effective Health Care Program
   effectivehealthcare.ahrq.gov/products/diabetes-treatment
   January 24, 2012 - Treatment Intensification in Type 2 Diabetes Mellitus Timeline January 24, 2012 Topic … Initiated January 24, 2012 Abstract Archived Treatment Intensification … in Type 2 Diabetes Mellitus

2. Treatment Intensification in Type 2 Diabetes Mellitus | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/products/diabetes-treatment/abstract
   January 24, 2012 - Treatment Intensification in Type 2 Diabetes Mellitus Abstract Archived January 24, 2012 … Topic Abstract Background: Many patients with type 2 diabetes mellitus (DM) may have other major … Patients often have their DM therapies intensified to reach the recommended hemoglobin A1C (HbA1C) target … ; and, 2) therapy intensified during the first year with insulin. … Three exposures will be examined: therapy intensified with an additional oral agent therapy intensified

3. Diabetes Mellitus (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/diabetes_hi_impact.pdf
   March 01, 2012 - Many patients with T2DM fail to meet treatment goals and require additional therapy with one of two … New treatments in development for all types of diabetes focus on several aspects of prevention to delay … treatment compliance Experts agreed that while any new therapy for the treatment of diabetes would … of T2DM Intervention SGLT2 inhibitors for treatment of T2DM While many current treatments help … A paradigm shift in diabetes therapy-- dapagliflozin and other SGLT2 inhibitors.

4. Diabetes Mellitus (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/diabetes_hi_impact.pdf
   March 01, 2012 - Many patients with T2DM fail to meet treatment goals and require additional therapy with one of two … New treatments in development for all types of diabetes focus on several aspects of prevention to delay … treatment compliance Experts agreed that while any new therapy for the treatment of diabetes would … of T2DM Intervention SGLT2 inhibitors for treatment of T2DM While many current treatments help … A paradigm shift in diabetes therapy-- dapagliflozin and other SGLT2 inhibitors.

5. Diabetes Mellitus (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/07_diabetes_potential_high_impact_june_2012.pdf
   January 01, 2012 - Many patients with T2DM do not meet treatment goals and require additional therapy with one of two … New treatments in development for all types of diabetes focus on delaying onset of the disease in at-risk … One expert with a clinical perspective also noted that initiation of treatment with this therapy might … Both treatments were generally well tolerated. … Treatment Adherence Diabetes Mellitus Interventions Artificial Pancreas for Treatment of Diabetes

6. Diabetes Mellitus (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/07_diabetes_potential_high_impact_2012-12-10.pdf
   January 01, 2012 - ) Therapy for Type 1 Diabetes Mellitus and Type 2 Diabetes Mellitus Requiring Insulin 5 Fluocinolone … New treatments in development for all types of diabetes focus on delaying disease onset in at- risk … of Type 2 Diabetes Mellitus  Key Facts: Two therapies for treating T2DM, one in development and … of Type 2 Diabetes Mellitus Two therapies for treating T2DM, one in development and one recently approved … of Diabetes Buccal Insulin (Oral-Lyn) Therapy for Type 1 Diabetes Mellitus and Type 2 Diabetes Mellitus

7. Diabetes Mellitus (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/07_diabetes_potential_high_impact_2012-12-10.pdf
   January 01, 2012 - ) Therapy for Type 1 Diabetes Mellitus and Type 2 Diabetes Mellitus Requiring Insulin 5 Fluocinolone … New treatments in development for all types of diabetes focus on delaying disease onset in at- risk … of Type 2 Diabetes Mellitus  Key Facts: Two therapies for treating T2DM, one in development and … of Type 2 Diabetes Mellitus Two therapies for treating T2DM, one in development and one recently approved … of Diabetes Buccal Insulin (Oral-Lyn) Therapy for Type 1 Diabetes Mellitus and Type 2 Diabetes Mellitus

8. Diabetes Mellitus (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1306.pdf
   January 01, 2016 - New treatments in development for diabetes focus on delaying disease onset in at-risk patients and … of Type 2 Diabetes Mellitus  Key Facts: Two therapies for treating T2DM, one in development and … therapies. … Other treatment options, such as anti-VEGF therapies are available for treating DME, and according … Intarcia Therapeutics. A study to evaluate ITCA 650 for the treatment of type 2 diabetes.

9. Diabetes Mellitus (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1312.pdf
   January 01, 2016 - New treatments in development for diabetes focus on delaying disease onset in at-risk patients and … of Type 2 Diabetes Mellitus  Key Facts: Two therapies for treating T2DM, one in development and one … These studies evaluated the safety and efficacy of EQW compared with other diabetes therapies. … ., anti-VEGF therapies). … Intarcia Therapeutics. A study to evaluate ITCA 650 for the treatment of type 2 diabetes.

10. Diabetes Mellitus (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1412.pdf
    January 01, 2015 - therapeutic effects and better glycemic control. … The mode of delivery, an implanted pump, is an established therapy for other drugs or other treatments … Unlike other treatments for T2DM, management of therapy with the ITCA 650 is controlled by the device … , corticosteroids, or anti-VEGF therapies, making this new intervention just another treatment option … Investigational therapeutic options in the management of DME: investigational pharmacologic treatments

11. Diabetes Mellitus (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1512.pdf
    December 01, 2015 - In a May 2015 review published in Diabetes Technology & Therapeutics of almost 21,000 patients who … 2 diabetes mellitus (T2DM) do not meet treatment goals and require additional therapy with one of … medications, behavioral and lifestyle therapies, glucose monitors, insulin pumps, and treatment protocols … medications, behavioral and lifestyle therapies, glucose monitors, insulin pumps, and treatment protocols … Investigational therapeutic options in the management of DME: investigational pharmacologic treatments

12. Diabetes Mellitus (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1406.pdf
    September 26, 2014 - of Type 2 Diabetes  Key Facts: ITCA 650 (Intarcia Therapeutics, Inc., Hayward, CA), is extended-release … The mode of delivery, an implanted pump, is an established therapy for other drugs or other treatments … Unlike other treatments for T2DM, management of therapy with the ITCA 650 is controlled by the device … , corticosteroids, or anti-VEGF therapies, making this new intervention just another treatment option … Investigational therapeutic options in the management of DME: investigational pharmacologic treatments

13. Diabetes Mellitus (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1506.pdf
    June 01, 2015 - with type 2 diabetes mellitus (T2DM) do not meet treatment goals and require additional therapy with … medications, behavioral and lifestyle therapies, glucose monitors, insulin pumps, and treatment protocols … medications, behavioral and lifestyle therapies, glucose monitors, insulin pumps, and treatment protocols … with diabetes to improve compliance with recommended therapy and success at attaining treatment goals … Investigational therapeutic options in the management of DME: investigational pharmacologic treatments

14. Effectiveness of Treatments for Diabetic Peripheral Neuropathy (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetic-neuropathy_research-protocol.pdf
    May 09, 2016 - Table A: Inclusion/Exclusion Criteria KQ1a(Pharmacologic treatments) KQ2a(Pharmacologic treatments) … KQ1b(Non-pharmacologic treatments) KQ2b(Non-pharmacologic For prevention of DPN Complications treatments … [tiab] OR therapies[tiab]) AND (moving[tiab] OR sports[tiab]))) OR “Stair Navigation”[tiab] OR postural … therapy”[tiab] OR “cognitive Psychotherapy”[tiab] OR “behavioral therapy”[tiab] OR “behavioral therapies … Xylocaine (Lidocaine) AstraZeneca Qutenza (Capsaicin) Acorda Therapeutics, Inc 20 !

15. Screening and Diagnosing Gestational Diabetes Mellitus | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/gestational-diabetes-screening-diagnosis/research
    November 05, 2012 - Systematic Review Mar. 4, 2013 Disposition of Comments Report Screening and Diagnosing Gestational Diabetes … ; any treatment for GDM with no treatment. … Prevalence of GDM varied across studies and diagnostic criteria: American Diabetes Association (75 g) … Treatment of GDM results in less preeclampsia and macrosomia. … , and the “real world” effects of GDM treatment on use of care.

16. Effective Health Care Program
    effectivehealthcare.ahrq.gov/health-topics/diabetes-0
    August 04, 2010 - A Retrospective Cohort Study of a New Therapy Research Report Archived August 4, 2010 … Transparency of Reporting Requirements: Effectiveness of Treatments Options for the Prevention … of Complications and Treatment of Symptoms of Diabetic Peripheral Neuropathy Research Protocol … Neuropathy Research Protocol Archived May 13, 2016 Distributed Ambulatory Research in Therapeutics … for Adults with Type 2 Diabetes: An Update Focused on Monotherapy and Add-on Therapy to Metformin

17. Gestational-Diabetes-Screening-Diagnosis Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/gestational-diabetes-screening-diagnosis_executive.pdf
    October 01, 2012 - The benefits and harms of treatments were considered in this review to determine the downstream effects … glucose monitoring, insulin therapy (all preparations), and oral hypoglycemic agents versus no treatment … For the remaining Key Questions, we may be missing unpublished and/or negative therapy studies and may … Therapeutic interventions. Diabetes Care. 1998;21(Suppl 2):B131-37. PMID: 9704240. 39. … Use of fetal ultrasound to select metabolic therapy for pregnancies complicated by mild gestational

18. Topic 0556 CE of Treatments for Diabetic Peripheral Neuropathy NSD SJ clean (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0658-140831.pdf
    July 19, 2014 - Topic 0556 CE of Treatments for Diabetic Peripheral Neuropathy NSD SJ clean … Comparative Effectiveness of Treatments … specifically at diabetic neuropathy progression or symptoms, such as lifestyle modifications, medical therapies … , complementary therapies, physical therapy, electrical nerve stimulation, and surgery Comparator(s) … of diabetic peripheral neuropathy in several treatment classes.

19. What are the best practice Behavioral Health programs for type 1 diabetes, type 2 diabetes and gestational diabetes. Does educational counseling help paitients improve control and adherence to treatment? | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/get-involved/nominated-topics/what-are-the-best-practice-behavioral-health-programs-for-type-1-diabetes-type-2-diabetes-and-gestational-diabetes-does-educational-counseling-help-paitients-improve-control-and-adherence-to-treatment
    May 04, 2012 - Briefly describe a specific question, or set of related questions, about a health care test or treatment … Does educational counseling help paitients improve control and adherence to treatment? … treatment modalities and behavioral intervention types. … Please include specific details such as age range, gender, coexisting diagnoses, and indications for therapy … (For example, improvements in patient symptoms or problems from treatment or diagnosis.)

20. Rehabilitation | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/health-topics/rehabilitation
    November 15, 2011 - Whole-Body Vibration Therapy for Osteoporosis Technical Brief Archived November 15, 2011 … Fibromyalgia in Adult Subgroups Systematic Review Archived January 26, 2015 Treatments … for Fibromyalgia in Adult Subgroups Research Protocol Archived April 3, 2014 Treatments … for Chronic Pain Research Protocol April 27, 2017 Noninvasive Treatments for … Systematic Review Systematic Review June 11, 2018 Noncyclic Chronic Pelvic Pain Therapies