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effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/white-paper-standardized-library.pdf
February 01, 2019 - Robotic
Registry
FDA created discussion paper
and held workshop to outline
topics related to the design
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/6cRgd5whkAvSGESSQsrQLR
January 01, 2020 - Evidence is insufficient because of
the limited number or size of studies.
important flaws in study design
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hcup-us.ahrq.gov/reports/statbriefs/sb75.pdf
June 01, 2009 - Statistical Brief #75: Sports Injuries in Children Requiring Hospital Emergency Care, 2006
HEALTHCARE COST AND
UTILIZATION PROJECT
Agency for Healthcare
Research and Quality
STATISTICAL BRIEF #75
Highlights
Sports-related injuries
accounted for one in five (22.0
percent) of the 1.4 m…
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/prostate-cancer-screening-1996
January 01, 1996 - -1.7). 48 A cohort study also reported little benefit from DRE screening, 49 but its methodologic design … cumulative survival rates over 15 years, but the study was conducted in the 1970s and suffered from several design
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digital.ahrq.gov/sites/default/files/docs/publication/r18hs018157-hazlehurst-final-report-2013.pdf
January 01, 2013 - Automating Assessment of Obesity Care Quality - Final Report
Grant Final Report
Grant ID: R18HS18157
Automating Assessment of Obesity Care Quality
Inclusive Project Dates: 09/30/09 – 03/31/13
Principal Investigator:
Brian Hazlehurst, PhD1
Team Members:
Mary Ann McBurnie, PhD1
Victor S…
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary43/prostate-cancer-screening-2012
October 07, 2011 - Extraction and Quality Assessment
One investigator abstracted details about the patient population, study design … Sample sizes ranged from 9026 to 182,160 and maximum follow-up from 11 to 20 years (median, 6 to 14 years … Sample sizes ranged from 72 to 44,630 and duration of follow-up from 1 to 23 years. … indication may be less of an issue in studies that evaluate harms 80 , and analyses stratified by study design … Cancer Intervention Versus Observation Trial: VA/NCI/AHRQ Cooperative Studies Program #407 (PIVOT): design
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary13/child-maltreatment-primary-care-interventions-2013
January 15, 2013 - English-language trials of the effectiveness of behavioral interventions and counseling and studies of any design … Studies of any design were included to describe potential adverse effects of behavioral interventions … Data Abstraction and Quality Rating
An investigator abstracted data about study design and setting; … Key Questions
Studies
Design … risk assessment or a clinic setting, or not a prevention focus (21); wrong outcome (27); wrong study design
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/ovarian-cancer-screening
February 13, 2018 - quality if attrition was greater than 40% or differed between groups by 20% or if there were other study design … The strict inclusion and exclusion criteria related to study design and outcome reporting excluded evidence … Otherwise, AHRQ had no role in the design and conduct of the study; collection, management, analysis, … Design: Study did not use an included design.
Language: Publication not in English.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/allergy-seasonal_research-protocol.pdf
March 08, 2012 - comparisons
o Report at least one outcome of interest
o High quality
Follow-up duration Unrestricted
Sample … size Unrestricted
Key Question 2—Comparative Adverse Effects of Treatments in Adults 12
Years of … Therefore study questions, design and/or methodological
approaches do not necessarily represent the … • Was there an attempt to balance groups by design?
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/palliative-care-research-amended-protocol.pdf
November 21, 2019 - For all articles, reviewers will extract information on general study characteristics
(e.g., study design … issues (e.g. fidelity, participant
recruitment, intervention
quality, participant
engagement)
Sample … size Analysis of interest includes
fewer than 10 participants
ii. … Reviewers will extract information from included
studies on general study characteristics (e.g. study design … Therefore, study questions, design, and methodological approaches do not
necessarily represent the views
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-immunotherapy-2010_research-protocol.pdf
January 01, 2010 - We will search the literature without imposed language, sample
size, or date restrictions. … representativeness, case definitions),
comparability of cohorts/cases and controls on the basis of design
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hcup-us.ahrq.gov/reports/methods/2011_01.pdf
January 01, 2011 - event of interest is rare, a
calendar year study period may be insufficient to obtain an adequate sample … size. … Study Design: The population is a selection of almost 1.5 million adult surgery patients
initially treated … potentially could be useful for health plans and their sponsors (employers, government)
when they design … Research Design And Methods: Using the Healthcare Cost and Utilization Project
complete discharge data
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/DYFdTVu-UY3h7CWGdA7Zkh
July 20, 2021 - Studies whose design was subject to a high
risk of bias were excluded, including those studies subject … Data Synthesis and Analysis
The results were synthesized by KQ, type of screening test, and study
design … Design: Study did
not use an included design. … Concept and design: All authors.
Acquisition, analysis, or interpretation of data: All
authors. … Empirical evidence of design-related bias in studies
of diagnostic tests.
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effectivehealthcare.ahrq.gov/sites/default/files/diabetes-update-2015_disposition-comments.pdf
January 01, 2015 - Affiliation Section Comment Response
TEP Reviewer #3 General Need better alignment of conclusions with design … drawing more
explicit connections between the comparisons and
key questions that were part of the design … high quality
evidence on many major clinical outcomes and how
difficult and expensive it will be to design … Discussions on the need for high-
quality observational studies and have made
suggestions regarding the design … This edit was made to
the Study Design and Population
Characteristics paragraph of the Key Question
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-knee-physical-therapy_executive.pdf
November 01, 2012 - treatment effect estimates as precise when pooled
estimates had reasonably narrow 95% CIs and pooled
sample … size was greater than 400. … Although the sample
size of the subgroup with physical therapist involvement
was smaller than the sample … size of all pooled studies, our
conclusions remain the same. … Design of clinical trials in knee
osteoarthritis: practical issues for debate.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/episodic-migraine-surveillance-report-2.pdf
June 01, 2022 - Comparative observational studies
Systematic reviews or meta-analyses (evaluating triptans and NSAIDs)
Any sample … size
Relevant systematic reviews, or meta-analyses (used for identifying
additional studies)
In … Characteristics of included studies
Author,
Year
Country,
Study Design,
Study Period
Study
Setting … [Study design not of interest]
6. Blumenfeld AM, Knievel K, Manack
Adams A, et al. … [Study
design not of interest]
30. Tepper SJ, Ashina M, Reuter U, et al.
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effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1512.pdf
December 01, 2015 - health care
communication than traditional mail or phone calls.16,17
Depending on the intervention’s design
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/asthma-immunotherapy-2010_disposition-comments.pdf
January 01, 2010 - drug’s
effects, to better understand “failings” in a given
study, and to optimize subsequent study design … any study, but in particular,
this study, requires a reviewer that has an
understanding of study design
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/B73a4kJhxeaYyXK6gozbbY
May 24, 2022 - Data Abstraction and Quality Rating
One investigator abstracted details about the study design, patient … the Vitamin E, Cataract, and Age-related Maculopathy (VECAT) study
(n = 1193).18 In the other trials, sample … sizes ranged from 14 to 433. … Concept and design: Chou, Jonas. … The Age-Related Eye
Disease Study 2 (AREDS2): study design and
baseline characteristics (AREDS2 report
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/stroke-atrial-fibrillation_executive.pdf
August 01, 2013 - three large
trials comparing novel anticoagulants with VKAs have
been completed, with a combined sample … size of ~50,000
subjects:
• RE-LY (Randomized Evaluation of Long-Term
Anticoagulation Therapy), with … These articles explored tools
in studies of diverse quality, design, geographical location,
and study … The studies were divided
between single-center and multicenter design and covered
broad geographical … Perhaps an
additional evidence gap, given the need for a large sample
size in an RCT addressing this