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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary39/obesity-in-children-and-adolescents-screening-2010
January 15, 2010 - Two investigators independently quality rated the studies by using design-specific criteria ( Appendix … our previous USPSTF review, in which we found study concerns echoed by others, 45 including small sample … sizes, high attrition rates (among other quality issues), less-than-ideal outcome measures, and highly … indeterminate result in a reasonable manner
Spectrum of patients included in study
Sample … size
Administration of reliable screening test
The nature of the test being studied
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/BM-D2tSCN9U8uuBFAufXaa
August 01, 2013 - In addition to use of a nonrandomized
design, other methodological short-
comings in the poor-quality … Sample sizes ranged from 280 to 1146
REVIEW ARTICLE
PEDIATRICS Volume 132, Number 2, August 2013 335 … Interventions Country; Setting;
Fluoridation Status
Age at
Enrollment
Sample
Size
F-U, y Mean Caries … Interventions Country; Setting;
Fluoridation Status
Age at
Enrollment
Sample
Size
F-U, y Mean Caries … Interventions Country; Setting;
Fluoridation Status
Age at
Enrollment
Sample
Size
F-U, y Mean Caries
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/ecWjjTgXCffjwPyqgNCEpR
February 01, 2006 - RCTs
that demonstrated improved speech and language outcomes had several limitations, such
as small sample … size, failure to consider potential confounders, the reporting of short-term
outcomes, and heterogeneous … effects on health outcomes because of limited
number or power of studies, important flaws in their design
-
www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/folic-acid-for-the-prevention-of-neural-tube-defects-preventive-medication-january-2017
January 10, 2017 - interpretation of study findings, results are presented first by study design, second by data source … flaws and inadequate sample size in these studies are also important considerations. … , 98 for wrong intervention, 1 for wrong sample size, 68 for wrong language/non-English, and 5 that were … Wrong study design: study did not include an eligible design. … Wrong sample size: study had 50 or fewer participants.
-
www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/vision-in-children-ages-6-months-to-5-years-screening
September 05, 2017 - Snellen chart) and 0.15 logMAR (between 1 and 2 lines). 40-42 Large treatment studies have calculated sample … size requirements based on the ability to detect a change of at least 0.1 logMAR between treatment groups … Sample sizes ranged from 63 75 to 4040. 70 , 91
About one-third of the studies included participants … Improving on ETDRS acuities: design and results for a computerised thresholding device. … Screening Intervention vs Control
Sample Size
Age
Female, No. (%) b
Non-White, No (%)
Main
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/ZrLh7o2TpPpY9WXXWbXbGk
January 01, 2013 - We also included large studies (sample size �1000 partic-
ipants) reporting harms associated with diagnostic … Studies of Alternative Screening Strategies
Study, Year; Country
(Reference)
Study Design Sample Size … negative psychological and social
effects, but results are difficult to interpret
because of small sample … sizes and
methodological shortcomings, including no
unscreened comparison group. … Author Contributions: Conception and design: R. Chou, J.M. Guise.
-
www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary15/blood-pressure-in-adults-hypertension-screening-2007
October 15, 2007 - For harms of early treatment, 2 reviewers abstracted information on sample size, entry criteria, demographic … characteristics, comorbid conditions, study design, treatment group allocation, reports of adverse effects … that were not on hypertension, 62 that included a high-risk population, 31 that did not meet study design … Year (Reference)
Study Objective
Sample Characteristics
Inclusion Criteria
Design
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/qCaKmh7ayuG9VP2vj646pQ
March 01, 2004 - From each included study, we abstracted the
study design, number of participants, setting,
3
Screening … Agency staff
and USPSTF members participated in the initial
design of the study and reviewed interim … • Sample size?
• Administration of reliable screening test? … size (50 to 100
subjects) and a “medium” spectrum of patients. … size of
very narrow selected spectrum of patients.
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/YFZy6kszQPq5tNGdZC25XC
July 26, 2016 - Evidence is insufficient because of
the limited number or size of studies.
important flaws in study design … possible, a high-quality case-
control study could provide sufficient power without requiring a
large sample … size. … However, this study design has limitations in the
ability to create an appropriate comparison group,
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/827CwGYMVawpVoVg_syJpF
October 01, 2015 - Eight studies
were conducted in the United States or Europe, 3 in
Iran, and 1 in Hong Kong; sample sizes … Studies were conducted in the United
States, Australia, Hong Kong, Ireland, Iran, and Norway;
sample … sizes ranged from 45 to 1164 participants. … sizes
ranged from 45 to 1164 participants. … Evidence is insufficient because of:
the limited number or size of studies;
important flaws in study design
-
www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/breastfeeding-primary-care-interventions
April 11, 2025 - One reviewer abstracted data about each study’s design, population, interventions, and outcomes; a second … Sample sizes for the included trials ranged from 39 to 9675 participants, and the median sample size … pregnancy: a cluster-randomized controlled trial to prevent excessive gestational weight gain—rationale and design … Study design: Study was not a randomized clinical trial.
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/CXDusYW7s2xdypXMpnW9sw
June 20, 2023 - excluded for KQ3
9 Intervention
7 Population
7 Setting
4 Aim
34 Outcomes
3 Comparator
2 Quality
2 Design … Design: Study did not use an included design. … antidepressants
are addressed in a separate publication.8 Evidence in the RCTs was
limited due to small sample … sizes (eTable 16 in the Supplement). … Concept and design: All authors.
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/DTRggkjEPQ5-ALArTjrhKT
July 11, 2017 - Characteristics of All Included Trials
Source
Study
Qualitya Country
Sample Size,
Population
Description … Characteristics of All Included Trials (continued)
Source
Study
Qualitya Country
Sample Size,
Population … Characteristics of All Included Trials (continued)
Source
Study
Qualitya Country
Sample Size,
Population … Characteristics of All Included Trials (continued)
Source
Study
Qualitya Country
Sample Size,
Population … Characteristics of All Included Trials (continued)
Source
Study
Qualitya Country
Sample Size,
Population
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/SJbAXUAQTv2GWemMuBab6W
April 08, 2025 - One reviewer abstracted data about each study’s design, popu-
lation, interventions, and outcomes; a … Sample sizes for the included trials ranged
from 39 to 9675 participants, and the median sample size … 13 Relevance
11 Quality
167 Articles excluded for KQ2
23 Quality
37 Outcomes
30 Setting
24 Study design … Study design: Study was
not a randomized clinical trial. … Concept and design: All authors.
Acquisition, analysis, or interpretation of data: All
authors.
-
www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/food-insecurity-screening
March 11, 2025 - Risk ratios are shown in a forest plot but not pooled due to the heterogeneity in study design, intervention … Design and implementation of a clinic-based food pharmacy for food insecure, uninsured patients to support … Design: Study did not use an included design. … Study design
Population
Identified via screening b
Provides free food
Provides vouchers
Provides … Insecurity
Study design
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/kGvn_HBPEEdfu2rs38VN8_
March 11, 2025 - 0 Articles included for KQ3
222 Articles excluded for KQ1a
159 Outcomes
33 Comparator
8 Setting
5 Design … type
1 Follow-up
0 Quality
223 Articles excluded for KQ3a
162 Outcomes
31 Comparator
8 Setting
5 Design … Design: Study did not use
an included design. … Summary of Evidence: Preventive Services for Food Insecurity
Study design (No. of observations) Summary … Concept and design: O’Connor, Webber, Martin,
Eder, Lin.
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/6L2obA88s86MoZDbWtMPTU
December 01, 2011 - Questions and Summary of Evidence Reviewed
KQs and Comparisons of
Interest
Outcomes Studies (Total Sample … Size)
Methodologic
Quality
Follow-up
Duration
Main Findings Supplement or
Appendix
Figure
Providing … Size)
Methodologic
Quality
Follow-up
Duration
Main Findings Supplement or
Appendix
Figure
Providing … size is specific to the comparison. … The size of the
circle is proportional to the sample size of the RCT.
-
www.uspreventiveservicestaskforce.org/uspstf/document/cost-effectiveness-analyses-of-population-based-screening-for-abdominal-aortic-aneurysm-evidence-synthesis/abdominal-aortic-aneurysm-screening-february-2005
February 15, 2005 - Quality grades were assigned based on a subjective assessment of study design and quality of data inputs … primarily on the uncertain quality of their effectiveness and/or cost data, even if most other favorable design … studies combined lower-quality effectiveness and/or cost data with an absence of most other favorable design … Also, most studies took the design of the screening program as given, especially the screening interval
-
www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/autism-spectrum-disorder-in-young-children-screening
February 16, 2016 - However, assessment of treatment evidence was complicated by the variation among studies in intervention design … In addition to the limitations of the evidence in size, study design, and other sources of heterogeneity
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/-UMtbPLHkQKcQCbeQ3gTuJ
September 01, 2013 - This difference also suggests possible
inadequate randomization or inadequate sample size, be-
cause … Furthermore, differences in popula-
tion characteristics and systems of medical care and the
small sample … sizes used in the European studies may limit
applicability to a U.S. population. … 146
Wrong publication type: 539
Non–English-language: 304
Wrong outcome: 98
Published before 2000: 22
Sample … size too small: 44
Follow-up too short: 1
Cohort studies (n = 13)
Screening key questions
(n = 54)