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www.uspreventiveservicestaskforce.org/home/getfilebytoken/VpT-c4bnmvHFRPyKgPwb2Z
December 01, 2010 - was
reduced in 1 trial
of first cataract
surgery
Medication
assessment
and
withdrawal
1 (47) Small sample … size
(48 participants)
NA NA Fair Limited evidence of
no benefit
Fall risk was not
reported
Home-hazard … Author Contributions: Conception and design: Y.L. Michael, E.P.
Whitlock, J.S. Lin, E.A. O’Connor. … Articles excluded for KQ 1
(n = 225)
Relevance: 97
Setting: 24
Population: 17
Quality: 18
Study design … Articles excluded for KQ 4
(n = 329)
Relevance: 112
Setting: 35
Population: 27
Quality: 23
Study design
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-aspirin/aspirin-nsaids-for-prevention-of-colorectal-cancer-preventive-medication-2007
March 15, 2007 - Included Studies: Aspirin Chemoprevention of Colonic Adenomas and Colorectal Cancer, by Study Design* … Its design, conduct, and reporting were based on specific directives from these agencies. … The Women's Health Study maintained the RCT design for the entire study period. … Not an eligible study design = 135.
Unable to obtain = 2." … Included Studies: Aspirin Chemoprevention of Colonic Adenomas and Colorectal Cancer, by Study Design*
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/cervical-cancer-screening
August 21, 2018 - in countries with organized screening programs such that even large trials did not have sufficient sample … size or duration to detect changes in invasive cervical cancer incidence, CIN 3 or worse (CIN 3+) was … Summary tables of study design, population characteristics, protocols, and intervention and follow-up … Design: Study did not use an included design. Language: Publication not in English. … Source
Study Design
-
www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary9/alcohol-misuse-screening-and-behavioral-counseling-interventions-in-primary-care-2013
September 25, 2012 - Sample sizes ranged from 72 to 1559, and study durations ranged from 6 to 48 months Appendix Table 3
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-pregnant-women1/human-immunodeficiency-virus-hiv-infection-screening
June 11, 2019 - Sample sizes ranged from 183 to 13,124 (total n = 71,472). … vs 3.2%, P = 0.43) or stillbirth. 9 Methodological limitations of the trial included open-label design … pregnancy and adverse outcomes in HIV-exposed uninfected infants and children using a trigger-based design … No. of Studies; No. of Participants; Study Design
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/zk8YxjaQxLGUTtt__nBQB_
September 09, 2021 - excluded for KQ3
9 Intervention
7 Population
7 Setting
4 Aim
34 Outcomes
3 Comparator
2 Quality
2 Design … for KQ4
31 Intervention
136 Population
89 Setting
5 Aim
104 Outcomes
19 Comparator
44 Quality
69 Design … for KQ5
30 Intervention
134 Population
89 Setting
6 Aim
267 Outcomes
22 Comparator
43 Quality
57 Design … Design: Study did not use an included design. … Concept and design: All authors.
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www.uspreventiveservicestaskforce.org/uspstf/document/comparative-effectiveness-of-antiviral-treatment-for-hepatitis-c-virus-infection-in-adults-a-systematic-review/hepatitis-c-screening-2013
November 15, 2012 - Data Extraction and Quality Assessment
One investigator abstracted details about the study design … Methodologic shortcomings included open-label design 55 or high attrition 22 . … Sizes, I
Cirrhosis at Baseline, %
Elevated Aminotransferase Levels at Baseline, %
Genotype Mix … § More than 2 times the upper limit of normal.
|| Sample sizes and results are restricted to patients … Sizes, n
Cirrhosis, %
Elevated
Aminotransferase
Levels, %
Boceprevir or Telaprevir
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary24/falls-prevention-in-older-adults-counseling-and-preventive-medication-2012
December 15, 2010 - cataract surgery
Single clinical treatment:
Medication assessment and withdrawal
1 47
Small sample … size (48 participants)
NA
NA
Fair
Limited evidence of no benefit
Fall risk was not reported … Reasons for exclusion were: relevance (n=97); setting (n=24); population (n=17); quality (n=18); study design … Reasons for exclusion were: relevance (n=112); setting (n=35); population (n=27); quality (n=23); study design … Reasons for exclusion were: relevance (n=5); population (n=2); quality (n=2); study design (n=18); outcomes
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/uhtgkZVs_bpNJ4_G4fXUay
March 01, 2014 - Evidence is insufficient because of:
the limited number or size of studies;
important flaws in study design
-
www.uspreventiveservicestaskforce.org/uspstf/recommendation/abdominal-aortic-aneurysm-screening-2014
June 23, 2014 - Share to Facebook
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Print
archived
Final Recommendation Statement
Abdominal Aortic Aneurysm: Screening
June 23, 2014
Recommendations made by the USPSTF are independent of the U.S. government.…
-
www.uspreventiveservicestaskforce.org/uspstf/recommendation/folic-acid-for-the-prevention-of-neural-tube-defects-preventive-medication-january-2017
January 10, 2017 - The newer studies are more subject to design issues than the older ones, which had fewer design flaws … ethnicity. 20 These inconsistent results among Hispanic women could be a result of chance due to small sample … sizes.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/r9MoffF79edExY5m2V_koD
May 01, 2021 - Abstraction and Quality Rating
A single investigator abstracted details from each study including
study design … in Iran29,40,48,49;
the others were conducted in Hong Kong,24 Australia,34 or
Europe.23,28,37,41
Sample … sizes ranged from 52 to 12 513 participants (total n =
23 844). … Four studies had more than 1000 participants; 3 were added
for this update, had the largest sample sizes … Concept and design: Cantor, Bougatsos,
DeLoughery, Chou.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/kAg43FLUnTjCU5ZNaaHQtW
March 01, 2016 - Evidence is insufficient because of:
the limited number or size of studies;
important flaws in study design
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/72ybMHDdg9WyFzrYMBF4ch
August 01, 2015 - In
addition to small sample sizes, some
studies were conducted in countries
with health care systems
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/dvDjnZzW9PDxzKBauB4QxA
August 21, 2018 - in countries with organized screening programs such that even large
trials did not have sufficient sample … size or duration to detect changes
in invasive cervical cancer incidence, CIN 3 or worse (CIN 3+) was … Summary tables of study design, population charac-
teristics, protocols, and intervention and follow-up … Design: Study did not use an
included design. Language:
Publication not in English. … Concept and design: Melnikow, Henderson,
Burda, Senger.
-
www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-latent-tuberculosis/latent-tuberculosis-infection-screening-september-2016
September 06, 2016 - Extraction and Quality Assessment
For each included study, one investigator extracted information about design … unlikely to be clinically relevant and can be explained by the number of included studies with large sample … sizes and precise estimates, a phenomenon that has been described as producing elevated I 2 estimates … comparator(s), 63 for ineligible or no outcome(s), 8 for ineligible setting, 36 for ineligible study design … Key Question
No. of Studies
No. of Participants
Study Design
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/pnyU5fxhdBUtCdvJ3GyqzR
March 01, 2007 - The PICOS
(participant, intervention/exposure, comparator, outcome
and study design) approach was applied … Its design, con-
duct, and reporting were based on specific directives from
these agencies. … These RCTs shared many sim-
ilarities, and the strength of their design adds weight to
these negative … The Women’s Health Study maintained the RCT
design for the entire study period. … Included Studies: Aspirin Chemoprevention of Colonic Adenomas and Colorectal Cancer, by Study Design*
-
www.uspreventiveservicestaskforce.org/uspstf/recommendation/speech-and-language-delay-and-disorders-in-children-age-5-and-younger-screening-july-2015
July 07, 2015 - In addition to small sample sizes, some studies were conducted in countries with health care systems
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/efwy72cuMdhcF2jotkhTzC
March 29, 2019 - Evidence is insufficient because of
the limited number or size of studies.
important flaws in study design … HIV-Infected Adults
(TEMPRANO ANRS) trial (n = 2056)30—and 3 large fair-quality
cohort studies, ranging in sample … size from 3532 to 55 826 (total
n = 63 478),31-33 that provided evidence on the benefits of early
initiation … pregnancy and adverse outcomes
in HIV-exposed uninfected infants and children
using a trigger-based design
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/ERAa_Bwr7hQxqZZ-X3p8Qh
May 10, 2022 - While no consistent benefit was seen among these trials it is
unclear if and how small sample sizes, … Concept and design: Webber, Lin.
Acquisition, analysis, or interpretation of data: All
authors.