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Total Results: 969 records

Showing results for "design sample size".

861. Disposition of Comments for Pharmacokinetic/Pharmacodynamic Measures for Guiding Antibiotic Treatment for Hospital-Acquired Pneumonia (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_disposition-comments.pdf
     November 24, 2014 - We think this covers the current future research needs for study design on this topic. … is absolutely no valid signal in these smaller studies, is there any reason to think that larger sample … sizes and better designs would change the results? … PK/PD approaches are beneficial, this may be difficult to prove without a trial with a very large sample … size.

862. Protocol: Imaging for Pretreatment Staging of Small Cell Lung Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/lung-cancer-staging_research-protocol.pdf
     December 08, 2014 - the Review Our inclusion criteria are listed below in five categories: Publication criteria, study design … Study Design Criteria a. … This design permits a Source: www.effectivehealthcare.ahrq.gov Published online: December 8, 2014 … Elements to be abstracted include general study characteristics (e.g., country, setting, study design … This instrument was developed by ECRI Institute12 with respect to the impact of study design on bias

863. DARTNet Summary Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/distributed-network-ambulatory-therapeutics_research.pdf
     July 01, 2009 - DARTNet Design Specifications B. … innovations that affect small populations (for which no single care delivery system would have a sufficient sample … size). … innovations that affect small populations (for which no single care delivery system would have a sufficient sample … size).

864. Disposition of Comments for Venous Thromboembolism Prophylaxis in Orthopedic Surgery (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/blood-clots-hip-knee-surgery_disposition-comments.pdf
     March 01, 2012 - Peer Reviewer #1 Executive Summary In the methods section, please justify how the sample size of … Peer Reviewer #1 Methods Please justify how the sample size of 750 was chosen for the observational … Peer Reviewer #1 Results 3.Study design and characteristics: When only a selection of included studies … Peer Reviewer #1 Results 2.Study design and characteristics: When only a selection of included studies … Peer Reviewer #1 Results 3.It is already stated in the study design and characteristics section that

865. Research Protocol (Amended): Treatment of Acute Pain--An Evidence Map (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/acute-pain-protocol-amended.pdf
     June 10, 2018 - Feasibility will be determined by the number and sample size of clinical trials available per topic.

866. Disposition of Comments for Technical Brief 18 Public Reporting of Cost Measures in Health (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/public-reporting-cost-measures_disposition-comments.pdf
     March 05, 2015 - is able to address them, or what methodological/framework problems need to be resolved in order to design … Given, the small sample size of semipublic websites that we had access to, we could not make definitive

867. Mrsa-Screening-2010 Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mrsa-screening-2010_executive.pdf
     January 01, 2010 - The Harbarth et al. study27 was a prospective interventional cohort study with crossover design of … All of the studies employed a quasi-experimental study design and were of poor quality. … The study by Rodriguez-Bano and colleagues31 utilized an interrupted time series design, as did the … an observational before/after design. … The cluster RCT is increasingly recognized as the optimal design for testing and evaluating the impact

868. final Fibromyalgia CER protocol_3-31-14 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/fibromyalgia_research-protocol.pdf
     April 03, 2014 - studies will be assessed by two independent investigators using instruments specific to each study design … Moderate risk of bias may be assigned to large cohort studies with a sample size for adequate power … first four domains.56 Study limitations will be rated as low, moderate or high according to study design … Therefore study questions, design and/or methodological approaches do not necessarily represent the … Study design: prospective, retrospective or mixed?

869. Searching for Relevant Studies (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/searching.ppt
     January 01, 2011 - Searching for Relevant Studies Searching for Relevant Studies Agency for Healthcare Research and Quality (AHRQ) Training Modules for Methods Guide for Effectiveness and Comparative Effectiveness Reviews Searching for Relevant Studies Systematic Review Process Overview * Systematic Review Process Overview …

870. Disposition of Comments Report for Procalcitonin-Guides Antibiotic Therapy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer78_procalcitonin_disposition_20121210.pdf
     October 05, 2012 - The first two research gaps are straightforward although not easy studies to design. … But difficult to design and implement in the real world. … appropriately note that definitively determining a mortality difference would require a very large sample … size. … and standard therapy and have a confidence interval that is narrow would require a large sample size

871. Disposition of Comments for CER 163 Appropriate Antibiotics (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antibiotics-respiratory-infection_disposition-comments.pdf
     January 27, 2016 - 105) as this study compared both POCT CRP and communication skills with usual care in a factorial design … was also able to do a head-to-head comparison of CRP and communication skills due to the factorial design … to compare all interventions using all outcomes, this would probably lead to an almost impossible design … The sample size of this study was less than 2000 patients, and as noted hospitalization is somewhat … The needed sample size would be about double.

872. Maternal, Fetal, and Child Outcomes of Mental Health Treatments in Women: A Systematic Review of Perinatal Pharmacological Interventions (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-236-maternal-fetal-child-outcomes-disposition-comments.pdf
     April 15, 2021 - estimates)” when talking about precision in general terms or “(i.e., the results relied on small sample … sizes, few events, or had wide CIs suggestive of both benefits and harms) when talking about imprecision … lack of adjustment for confounding, were any of the comparison studies sufficiently large in their sample … size or sufficiently reasonable in their design that they offer any useful information to clinicians

873. Evidence-Summary-CER-209-Noninvasive-Nonpharmacological-Treatment-For-Chronic-Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-209-evidence-summary-non-pharma-chronic-pain.pdf
     June 01, 2018 - and research recommendations Research Component Evidence Gap Future Research Recommendation Study Design … provided in included trials Documentation of coexisting conditions and factors in trials with sufficient sample-size

874. Treatments for Schizophrenia in Adults: A Systematic (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/executive-summary-2017-schizophrenia-adult.pdf
     January 01, 2017 - • Sample size of >50 for Key Question 2. … sizes <50 patients and studies conducted in countries that were not United States-relevant (primarily … Interventions/Comparisons The evidence in this review, by design, applies only to the comparisons with … sizes to address important health outcomes, rather than intermediate or surrogate outcomes and should … sizes to allow meaningful subgroup analysis

875. PowerPoint Presentation (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-strength-evidence.ppt
     June 01, 2012 - Risk of bias How study type/design/conduct may have contributed to systematic bias must be considered … The type and design of the study and how it is conducted can each contribute to systematic bias. … It is integrally related to sample size. … Precision is affected by the width of the confidence intervals and sample size. … Variability in study results is explained by differences in study design, patient population or test

876. PowerPoint Presentation (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-strength-evidence.ppt
     June 01, 2012 - Risk of bias How study type/design/conduct may have contributed to systematic bias must be considered … The type and design of the study and how it is conducted can each contribute to systematic bias. … It is integrally related to sample size. … Precision is affected by the width of the confidence intervals and sample size. … Variability in study results is explained by differences in study design, patient population or test

877. CER 173 Executive Summary: Diabetes Medications for Adults With Type 2 Diabetes: An Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/diabetes-update-2015_executive.pdf
     January 01, 2015 - • We included randomized trials that used a crossover design, with some exceptions. • Only studies … Because of low event rates and sample size, the pooled studies for most comparisons on these outcomes … considered current. 22 Database requirements for such observational studies include sufficient sample … size, followup of patients over time, detailed data on treatments (including doses and duration),

878. White Paper_Living Systematic Reviews: Examining Excluded Full-Text Articles To Better Understand the Evidence Base on Plant-Based Treatments for Chronic Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/living-systematic-reviews-full-text-articles-white-paper.pdf
     January 01, 2024 - Among the uncontrolled studies, sample sizes ranged from 7 to 8,165 (mean 551, median 151). … A randomized, double-blind, placebo- controlled, parallel-group, enriched-design study of Nabiximols … Trial Novotna, A.52 2011 A randomized, double-blind, placebo-controlled, parallel-group, enriched-design … A randomized, double-blind, placebo- controlled, parallel-group, enriched-design study of nabiximols

879. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_disposition-comments.pdf
     September 01, 2011 - As suggested by the reviewer, the greatest risks of bias are related to study design and implementation … Unfortunately, the sample size precluded this analysis. … I also think it would be informative if the sample sizes of individual studies were made explicit in … Study sample sizes are included in Tables 4, 5, and 6. … We added a statement that the leflunomide vs. methotrexate study was a non-inferiority study design

880. Evidence-based Practice Center Systematic Review Protocol: Depression in Children: Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-childhood-protocol.pdf
     August 06, 2018 - Inpatient care, studies conducted in countries without a very high Human Development Index Study design … All other designs and studies using included designs that do not meet the sample size criterion … When studies with sample sizes of 1,000 or more participants are available for a given intervention … If large samples are not available, we plan to include studies with smaller sample sizes http://hdr.undp.org … Therefore, study questions, design, and methodological approaches do not necessarily represent the views