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Total Results: 969 records

Showing results for "design sample size".

841. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism_executive.pdf
     April 01, 2011 - size to accrue adequate data on safety and tolerability as well as efficacy. … Single-subject design studies were not excluded on the basis of their design; however, the majority of … Even in studies with a comparison group, sample size is frequently insufficient to draw conclusions. … the outcome that was the primary outcome of a priori interest and on which, presumably, they based sample … - size calculations (when these calculations were present).

842. A Bayesian Missing Data Framework for Multiple Continuous Outcome Mixed Treatment Comparisons (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/indirect-comparisons_research-2013.pdf
     January 01, 2013 - sizes overall than for the pain outcome. … Figure 2 illustrates the design of the simulated complete and partially missing data. … For simplicity, we assume that every study has sample size 100 and standard deviation of 2 for every … size and assumed standard deviation, and true values were somewhat arbitrarily selected. … sizes and standard deviations.

843. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-treatment_research-protocol.pdf
     February 10, 2010 - 2011 Page 9 of 18 Follow-up duration >4 weeks post intervention < 4 weeks post intervention Sample … size N > 10 N < 10 B. … The basic elements and design of the evidence table will be the same as multiple tables we have used … Generally, a good-quality study meets all criteria for that study design; a fair-quality study does … Therefore study questions, design and/or methodological approaches do not necessarily represent the

844. Identification and Treatment of Post-Acute Coronary Syndrome (ACS) Depression: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/acs-depression-research-protocol-amended.pdf
     February 15, 2017 - • Original peer-reviewed data • KQ 1: Observational studies, sample size ≥50 subjects • KQ 2: Randomized … controlled trials (RCTs), sample size ≥20 subjects Editorials, nonsystematic reviews, letters, … They had serious errors in design, analysis, or reporting; large amounts of missing information; or … Influence of trial sample size on treatment effect estimates: meta-epidemiological study. … Therefore study questions, design, and methodological approaches do not necessarily represent the views

845. Schedule of Visits and Use of Telemedicine for Routine Antenatal Care: A Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/antenatal-care.pdf
     January 01, 2020 - • Comparative studies (comparisons of different interventions), including parallel design, pre-post … • Comparative studies (comparisons of different interventions), including parallel design, pre-post … (This sample size chosen because the upper 97.5% confidence interval bound for a proportion of 0/400 … For each study, we will extract publication data, study design features, population characteristics, … For each study, we will extract publication data, study setting, and study design features (e.g.,

846. Disposition of Comments CER 219 Antipsychotics for the Prevention and Treatment of Delirium (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/delirium-disposition-comments.pdf
     September 03, 2019 - Peer Reviewer #1 Results Evidence Summary > Results: Consider mentioning total sample size between … version of this report particularly when we were unable to calculate a summary measure, we detailed the sample … sizes and description of individual studies. … We state, “When scoring study limitations, we considered how well the study design and the study methods … importance by our panel of experts and key informants, studies did not exist or were insufficient in design

847. Hypertension-Pulmonary-Arterial Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/hypertension-pulmonary-arterial_research-protocol.pdf
     January 30, 2013 - online: January 30, 2013 11 Study Characteristic Inclusion Criteria Exclusion Criteria Study design … DistillerSR data synthesis software program (Evidence Partners Inc., Manotick, ON, Canada).We will design … adverse events, in particular including those related to administration or monitoring of treatment; sample … size sufficient to assess minimally important differences from a patient perspective; and use of intention-to-treat-analysis … Therefore study questions, design and/or methodological approaches do not necessarily represent the

848. Nppv-Respiratory-Failure Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/nppv-respiratory-failure_executive.pdf
     July 01, 2012 - outcomes, flexibility of the intervention and study duration, assessment of adverse effects, adequate sample … size for important health outcomes, and intention-to-treat approach to analyses. … For risk of bias we considered basic (e.g., RCT) and detailed study design (e.g., adequate randomization … Number of Studies (Subjects) Domains Pertaining to SOE Strength of Evidence Risk of Bias: Study Design … • Few studies had adequate sample sizes to address effects on length of stay.

849. Migraine-Emergency Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-emergency_executive.pdf
     November 01, 2012 - The search strategy did not employ any study design search filters, nor were language restrictions … Single trials, particularly those with small sample sizes, were graded as having insufficient strength … Sample sizes varied, with an overall median of 64 patients per study (interquartile range: 40 to 100 … A small number of studies and overall small sample sizes contributed to imprecision. … Equivalence claims would require considerably larger sample sizes and 95% CIs that do not include the

850. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/dementia-nursing-home-characteristics_research-protocol.pdf
     November 03, 2011 - of the population with dementia is <80% a Geography  United States  All other countries b Sample … Size  Trials with an N ≥ 30 c  Observational studies, if included, N ≥ 100 f  Trials with … We will design data abstraction forms to gather pertinent information from each article, including … A “poor” study has significant bias (e.g., stemming from serious errors in design or analysis) that … Therefore study questions, design and/or methodological approaches do not necessarily represent the

851. Long-Term Care for Older Adults Disposition of Comments Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/long-term-care-adults_disposition-comments.pdf
     November 07, 2012 - It would have been useful to have added the sample size and the period of the data collection to Tables … Sample size is a critical variable in determining the value of the study. … It is impossible to expect the reader to go back and forth between the design of the studies and the

852. Disposition of Comments for Pharmacokinetic/Pharmacodynamic Measures for Guiding Antibiotic Treatment for Hospital-Acquired Pneumonia (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_disposition-comments.pdf
     November 24, 2014 - We think this covers the current future research needs for study design on this topic. … is absolutely no valid signal in these smaller studies, is there any reason to think that larger sample … sizes and better designs would change the results? … PK/PD approaches are beneficial, this may be difficult to prove without a trial with a very large sample … size.

853. Protocol: Imaging for Pretreatment Staging of Small Cell Lung Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/lung-cancer-staging_research-protocol.pdf
     December 08, 2014 - the Review Our inclusion criteria are listed below in five categories: Publication criteria, study design … Study Design Criteria a. … This design permits a Source: www.effectivehealthcare.ahrq.gov Published online: December 8, 2014 … Elements to be abstracted include general study characteristics (e.g., country, setting, study design … This instrument was developed by ECRI Institute12 with respect to the impact of study design on bias

854. DARTNet Summary Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/distributed-network-ambulatory-therapeutics_research.pdf
     July 01, 2009 - DARTNet Design Specifications B. … innovations that affect small populations (for which no single care delivery system would have a sufficient sample … size). … innovations that affect small populations (for which no single care delivery system would have a sufficient sample … size).

855. final Fibromyalgia CER protocol_3-31-14 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/fibromyalgia_research-protocol.pdf
     April 03, 2014 - studies will be assessed by two independent investigators using instruments specific to each study design … Moderate risk of bias may be assigned to large cohort studies with a sample size for adequate power … first four domains.56 Study limitations will be rated as low, moderate or high according to study design … Therefore study questions, design and/or methodological approaches do not necessarily represent the … Study design: prospective, retrospective or mixed?

856. Disposition of Comments Report for Procalcitonin-Guides Antibiotic Therapy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer78_procalcitonin_disposition_20121210.pdf
     October 05, 2012 - The first two research gaps are straightforward although not easy studies to design. … But difficult to design and implement in the real world. … appropriately note that definitively determining a mortality difference would require a very large sample … size. … and standard therapy and have a confidence interval that is narrow would require a large sample size

857. Evidence-Summary-CER-209-Noninvasive-Nonpharmacological-Treatment-For-Chronic-Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-209-evidence-summary-non-pharma-chronic-pain.pdf
     June 01, 2018 - and research recommendations Research Component Evidence Gap Future Research Recommendation Study Design … provided in included trials Documentation of coexisting conditions and factors in trials with sufficient sample-size

858. Treatments for Schizophrenia in Adults: A Systematic (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/executive-summary-2017-schizophrenia-adult.pdf
     January 01, 2017 - • Sample size of >50 for Key Question 2. … sizes <50 patients and studies conducted in countries that were not United States-relevant (primarily … Interventions/Comparisons The evidence in this review, by design, applies only to the comparisons with … sizes to address important health outcomes, rather than intermediate or surrogate outcomes and should … sizes to allow meaningful subgroup analysis

859. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_disposition-comments.pdf
     September 01, 2011 - As suggested by the reviewer, the greatest risks of bias are related to study design and implementation … Unfortunately, the sample size precluded this analysis. … I also think it would be informative if the sample sizes of individual studies were made explicit in … Study sample sizes are included in Tables 4, 5, and 6. … We added a statement that the leflunomide vs. methotrexate study was a non-inferiority study design

860. Evidence-based Practice Center Systematic Review Protocol: Depression in Children: Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-childhood-protocol.pdf
     August 06, 2018 - Inpatient care, studies conducted in countries without a very high Human Development Index Study design … All other designs and studies using included designs that do not meet the sample size criterion … When studies with sample sizes of 1,000 or more participants are available for a given intervention … If large samples are not available, we plan to include studies with smaller sample sizes http://hdr.undp.org … Therefore, study questions, design, and methodological approaches do not necessarily represent the views