-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/fecal-incontinence_research-protocol.pdf
November 30, 2014 - studies will be assessed by two independent investigators using
instruments specific to each study design … Moderate risk of bias
may be assigned to large cohort studies with a sample size for adequate power … Study limitations will be rated as low, moderate, or high according to study design and
conduct. … Therefore study questions, design, and methodological
approaches do not necessarily represent the views … Study design:
prospective,
retrospective, or mixed?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_disposition-comments.pdf
September 10, 2014 - assessment is by
definition subjective and cannot always distinguish
between poor reporting and poor design … determined by the
threshold for performing biopsy and affects yield)
is a critical aspect in the design … I have some concern about the levels of bias and
strength of conclusions related to study design.
-
effectivehealthcare.ahrq.gov/sites/default/files/data-extraction.ppt
January 01, 2009 - In: Design and analysis of ecological experiments; 1993.
Data Extraction: A Boring Task? … Design and analysis of ecological experiments. New York: Chapman & Hall; 1993. p. 347-70. … Data Elements: Timing and Study Design
The data elements to be extracted vary by type of study. … Although there are common generic elements, forms need to be adapted to each topic or study design to … Design and analysis of ecological experiments. New York: Chapman & Hall; 1993. p. 347-70.
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-240-acute-pain-evidence-summary.pdf
December 01, 2020 - a potential marker for publication bias) due to small numbers of
trials and heterogeneity in study design
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/search-strategy-white-paper.pdf
February 01, 2025 - many of the processes involved in the conduct of systematic reviews,
particularly search strategy design … Several of these are intended to help with the design and conduct of search strategies. … literature websites.
14
Conclusion
Software tools have the potential to improve the search-design … tables may allow search designers to
identify the tools available to them at each step of the search-design … Sample Size Search (SSS) Tool for PubMed exclusion reason: no longer available.
67.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/diabetes-behavior-programs_executive.pdf
September 11, 2015 - pairwise
meta-analysis when two or more eligible trials were
sufficiently similar on the basis of study design … size and variance. … included studies
n = 11
Number of full-text articles
excluded
n = 504
Reasons for exclusion:
• Design … Plot of network meta-analysis results for HbA1c
17
few studies, small sample sizes, and/or wide credibility … Some studies had
small sample sizes, and a few failed to achieve baseline
comparability in their samples
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/major-depressive-disorder_research-protocol.pdf
November 24, 2014 - Retrospective controlled cohort studies
- Case-control studies
- Nonrandomized studies must have a
minimum sample … size of 500
participants
• Case series
• Case reports
• Nonsystematic reviews
• SRs without meta-analyses … We will design data abstraction forms to gather pertinent information
from each article. , including … assessment, population
characteristics (such as age, sex, race or ethnicity, or mean disease duration), sample … size,
loss to followup, withdrawals because of adverse events, results, and adverse events
reported
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/psoriasis-chronic_disposition-comments.pdf
November 27, 2012 - compared to placebo) from different studies that have very
similar inclusion/exclusion criteria and design … In fact, almost all biologic trials
are placebo-controlled and are similar, if not exact, in design. … The specific
comparisons in each study as well as the
sample size can be found in Appendix Table
4 … The study type,
specific comparisons in each study, sample
size, inclusion and exclusion criteria,
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-anemia-update_disposition-comments.pdf
April 25, 2013 - This outlines the broad design and
analysis of a registry that could likely address the important
unanswered … Was each individual trial weighted equally, or were trials weighted in some way
by sample size? … size across
the body of evidence is reasonably large (e.g.,
4000 patients), EPCs can consider the … sizes no survival effect
could be estimated. … size, to
compare observed risks that occur in clinical trials.16 The risk difference is
important
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/patient-centered-medical-home_disposition-comments.pdf
July 03, 2012 - PCMH evaluations suffer inherently from
sample size needed to assess impacts on clinical and economic … - When measuring effect size, was each study weighted equally or
were studies with larger sample sizes … Identify where investments in design and measurement of PCMH
process and outcomes should be made to
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/disruptive-behavior-disorder_research-protocol.pdf
January 30, 2014 - as this date cutoff aligns with the availability of the DSM-
IV.70
We will not specify a minimum sample … size (i.e., number of participants per arm) for
eligible studies. … We
intend to exclude entirely studies with a fatal flaw (i.e., a deficit of design or conduct
that … will use established concepts of the quantity of evidence (e.g., numbers of
studies, aggregate ending-sample … sizes), the quality of evidence (from the quality
ratings on individual articles), and the coherence
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-diff-infections_research-protocol.pdf
May 24, 2010 - Source: www.effectivehealthcare.ahrq.gov
Published Online: May 24, 2010
justification of the sample … size. … They have serious errors in design, analysis, or reporting;
large amount of missing information; or … Therefore study questions, design and/or
methodological approaches do not necessarily represent the
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/wic-outcomes-nutrition-protocol-amended.pdf
October 01, 2020 - The articles will not be excluded based on the study design and outcome at this level. … For all articles, reviewers will extract information on general study characteristics (e.g., study
design … with quantitative studies, we will extract information on general study characteristics
(e.g., study design … When possible, we will
stratify our findings by population, study design, and intervention (e.g. nature … Therefore, study questions, design, and methodological
approaches do not necessarily represent the views
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ems-blood-transfusion-protocol-amendment.pdf
February 04, 2025 - The key dilemma for EMS system
design is determining what options are feasible and sustainable for individual … Consideration should be given to the formulation of
precise scientific questions, optimal study design … The criteria used will depend on the study design as recommended in the chapter, “Assessing the
Risk … the width of confidence intervals relative to a clinically important effect
estimate, sufficiency of sample … size, and number of events.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/disparities-quality-improvement_executive.pdf
August 01, 2012 - A minimum sample size of 50 individuals per study and intervention group or subgroup. … (e.g., minimum effect size, standard error) to inform a power calculation, we
derived the minimum sample … size from expert opinion. … benefit from intervention
compared with Whites during any time period.
6
Author, Year,
Study Design … Summary of effects on disparities in health outcomes associated with sex
Author, Year, Study
Design
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_executive.pdf
September 01, 2011 - 3 fair trials: no significant differences in
remission maintenance of remission; however, small
sample … sizes in two of the studies and the
presence of a co-intervention in the third
study make results … A single study with a
small sample size indicated no difference in
withdrawals due to adverse events … TRD
patients with MDD compared with those with
bipolar disorder will help guide future clinical trial
design
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-anemia-update_research-protocol.pdf
June 16, 2010 - Sample size and extent of missing data will
be extracted. … • Trial characteristics: design, method of randomization, concealment of
allocation, blinding of … • Patients: sampling, exclusion criteria, sample size, baseline characteristics,
similarity of … size), or data with consistently defined outcomes across trials … Therefore study questions, design, and/or methodological approaches do not
necessarily represent the
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-urinary-retention_research.pdf
September 01, 2014 - Studies enrolled a total of 139 patients with sample sizes ranging from 13 to 86. … sizes. … Studies enrolled a total of 139
patients with sample sizes ranging from 13 to 86. … No differences between groups were reported; however, the small
sample sizes were likely unable to detect … Not addressed by current
literature
Larger sample sizes will enable this
type of analysis
a One
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/infertility_research-protocol.pdf
October 12, 2015 - design! •! Original!data,!including!systematic!reviews!and!meta0analyses!
•! RCTs,!prospective!and! … sample!sizes!
•! Observational!studies:!sample!size!≥100!subjects!
!
Editorials,! … We will design the data abstraction forms for this project to collect the data required to
evaluate … -based studies) and study design (e.g., RCT versus observational) that may be
related to outcomes. … They had serious errors in design, analysis, or reporting; large
amounts of missing information; or
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism_executive.pdf
April 01, 2011 - size to accrue adequate data on safety and
tolerability as well as efficacy. … Single-subject design studies were not excluded on the
basis of their design; however, the majority of … Even in studies with a comparison group, sample size is
frequently insufficient to draw conclusions. … the
outcome that was the primary outcome of a priori
interest and on which, presumably, they based sample … -
size calculations (when these calculations were
present).