-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostatic-hyperplasia-medications_research-protocol.pdf
April 21, 2015 - Study Design • Efficacy/comparative effectiveness: RCTs
Harms: RCTs and large observational studies … (medication for treatment of
LUTS/BPH, sample size at least 100; study duration at least 6 months; … sponsorship,
setting, subject inclusion and exclusion criteria, intervention and control characteristics,
sample … size, follow-up duration, participant baseline age, race, and AUA/IPSS scores,
and results of primary … Therefore
study questions, design, and methodological approaches do not necessarily represent the
views
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/research-gap-primary-care-summary-table.pdf
March 01, 2022 - • Study design. … general, longer followup periods, study expansion to multiple sites, and the recruitment of
larger sample … sizes can help address evidence gaps … Study Design
• Trials with sufficient sample size designed to
evaluate differential effectiveness … size to evaluate the differential impact of
conditions and factors.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/disposition-of-comments-cer-192-anxiety-in-children.pdf
August 31, 2017 - that
determined if the methods of studies
were strong enough to remain in the
evidence pool (e.g., sample … sizes per
cell [e.g., Mancini, 1999],
inclusion/exclusion criteria,
operationalization and control … NIMH funded
or small studies), we believe that the
issue is not about who funded the
study or the sample … size of the
study.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/worker-safety-wellness-protocol.pdf
October 26, 2024 - Each
longitudinal study will be described in summary and evidence tables presenting study design
features … 2: We will summarize the associations evaluated in the cross-sectional studies with the largest
sample … sizes. … We refrain from picking a sample size threshold to define ‘largest’ because at
best such a threshold … Therefore, study questions, design, and methodological
approaches do not necessarily represent the views
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ems-blood-transfusion-protocol.pdf
September 24, 2024 - The key dilemma for EMS system
design is determining what options are feasible and sustainable for individual … Consideration should be given to the formulation of
precise scientific questions, optimal study design … The criteria used will depend on the study design as recommended in the chapter, “Assessing the
Risk … the width of confidence intervals relative to a clinically important effect
estimate, sufficiency of sample … size, and number of events.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/vte-prophyalaxis_disposition-comments.pdf
May 29, 2013 - size in the thousands, a methodologically-appropriate RCT is not possible
and will never be carried … Therefore, as a reader, I would like to have the authors
design a theoretical study. … For example, based on their review of the literature, what
sample size would be required to perform … Details
regarding the sample size of such studies
are context specific and beyond the scope
of this … Our
updated future research section provides
guidance on the design of such studies.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-275-people-with-disabilities-disposition-comments.pdf
September 16, 2024 - Public
Reviewer #1
University of
Connecticut
Executive
summary
Appropriate design and communication … As described in the Methods section (“Systematic Review
Procedures”), we considered various study design … Public
Reviewer #1
University of
Connecticut
Methods Appropriate design for the purpose of this … Pg 13 line 4 – consider reporting sample size of
patients with Parkinsons as well as sample size of … The study did not report the sample sizes of patients and
caregivers separately.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism-update_research-protocol.pdf
September 20, 2013 - publication, study location (e.g.,
country, city, state) and time period, population description, sample … size, and study type (e.g.,
randomized controlled trial, prospective observational study, etc.). … will use established concepts
of the quantity of evidence (e.g., numbers of studies, aggregate ending-sample … sizes), the quality
of evidence (from the quality ratings on individual articles), and the coherence … Therefore study questions, design, and/or methodological
approaches do not necessarily represent the
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-protocol.pdf
January 01, 2024 - study is
multinational, at least one study center is in
a country rated very high)
N/A
Study Design … We will not apply different initial
SOE ratings based on study design, as ROBINS-I was designed so an … the width of confidence intervals relative to a clinically
important effect estimate, sufficiency of sample … size, and number of events. … Therefore,
study questions, design, and methodological approaches do not necessarily represent the
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/smoking-pregnancy-infants_executive.pdf
February 01, 2014 - The team
established this minimum sample size to balance the
need for smaller studies of specialized … period Database inception to present
Publication languages English only
Admissible evidence
(study design … Methodologic and study design considerations for future
research include—
• Clear characterization … • Adequate sample sizes with long-term followup. … Larger sample sizes are
needed to assess comprehensively infant and longer
term child outcomes as well
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-pci-bypass_surveillance.pdf
May 01, 2013 - (((clinical trial* or clinical trials or clin*) adj25 trial*) or placebo* or random* or "research design … Evidence Table
Author, year Study design Comparison Sample size Results
Serruys, 200912
(SYNTAX
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-protocol-amended.pdf
February 07, 2025 - Index (if study is
multinational, at least one study center is in
a country rated very high)
Study Design … We will not apply different initial
SOE ratings based on study design, as ROBINS-I was designed so an … the width of confidence intervals relative to a clinically
important effect estimate, sufficiency of sample … size, and number of events. … Therefore,
study questions, design, and methodological approaches do not necessarily represent the
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rapid-reviews-end-user_white-paper.pdf
April 01, 2016 - Therefore, in the end, study questions, design, methodological approaches, and/or conclusions do
not … size. … However, our small sample size means that results may not be
representative of all end-users and we … Future Directions
Our small sample size meant that we could not make definitive statements in comparing … A
possible design is the completion of a systematic review and a rapid review product on the same
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd-update_research-protocol.pdf
August 18, 2016 - comparison of diagnosis in primary care to diagnosis by a
specialist
• Randomized controlled trials: sample … size ≥20 subjects
• Observational studies: sample size ≥20 subjects
Editorials, nonsystematic
reviews … We will design the data abstraction forms for this project to collect the data required to
evaluate … They had serious errors in design, analysis, or reporting; large
amounts of missing information; or … Therefore study questions, design, and methodological approaches do not
necessarily represent the views
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/c-diff-infections_disposition-comments.pdf
March 01, 2012 - This paper, published in June, meets criteria
with a before-after study design and was
added to results … criteria for " good quality
studies" that identified specific risk factors were "(1) prospective
study design … Although the sample
size is extremely small, the 1989 NEJM article by McFarland et al
found contamination
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/phenylketonuria_research-protocol.pdf
March 29, 2011 - Time period All years
Publication languages English only
Admissible evidence (study
design and … publication, study location (e.g.,
country, city, state) and time period, population description, sample … size, and study type
(e.g., RCT, prospective observational study, etc). … , 2011
EPC Protocol – Version 8 – 12.22.10
evidence (e.g., numbers of studies, aggregate ending sample … sizes), the quality of
evidence (from the quality ratings on individual articles), and the coherence
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/tonsillectomy_research-protocol.pdf
February 10, 2016 - larger observational studies
of harms of tonsillectomy in the literature, and the larger sample … size should allow us to
capture data on rarer adverse events.
… established concepts of the quantity of evidence (e.g.,
numbers of studies, aggregate ending-sample … sizes), the quality of evidence (from the
ROB ratings on individual articles), and the … Therefore study questions, design, and methodological approaches do not
necessarily represent
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/coronary-artery-stenting_executive.pdf
February 01, 2013 - Size and Study Design
We did not specify a minimum sample-size threshold
or a minimum duration of … We considered evidence to be
sparse if only one study of a small sample size addressed
the analysis … Individual studies evaluated in formulating the composite
rating differed in their design, reporting … size). … considerably
since then, not only in terms of high-pressure balloon
inflation, but also in stent design
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/stakeholders-engagement-others_white-paper.pdf
September 01, 2013 - The design of a successful virtual platform requires technical
expertise, patient-user involvement, … • More control of design. … Disadvantages of joining a pre-existing PPRN:
• Less autonomy/control of design. … Some PPRNs offer a
standardized design and data collection template, and may not allow for significant … On
the Design of Compliance Governance
Dashboards for Effective Compliance and
Audit Management.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-231-dementia-care-interventions-disposition-comments.pdf
July 31, 2020 - Peer (TEP)
Reviewer #5
Methods Page 24, line 53, Table 2.1, Study Design – What does
the asterisk … This may be the
reason for smaller sample sizes and limited
generalization of findings. … The description of the methods section notes that
pilot studies and small sample size studies were … key study factors within each study were
considered when making comparisons across studies,
such as sample … size, effect size, program/intervention
dosage, sample characteristics, study design, and
measurement