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Showing results for "design sample size".

361. Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: 2022 Update of the PTSD-Repository Evidence Base (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-dispositIon-comments-2022.pdf
     January 01, 2022 - The PTSD-Repository is meant to capture all RCTs, regardless of sample size.

362. Disposition of Comments_Comparative Effectiveness Review No. 262_Pharmacotherapy for Adults With Alcohol Use Disorder in Outpatient Settings: Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-262-pharmacotherapy-alcohol-disposition-comments.pdf
     November 07, 2023 - It would be helpful to know the sample sizes of each and which trial had insufficient data vs. both … Thank you, we have revised this to two sentences and added the sample sizes for both trials. … Public Comment #3 (APA) Results p. 32 table N HDD N seems to mean something other than sample size … The sample size issues addressed in the last sentence seem like less of a focus of the GRADE and EBPC … Although the sample sizes are factored into the meta-analytic weightings, not all of the studies were

363. Use of Observational Studies in Systematic Reviews of (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/methodsguidenorris_060420101.pdf
     June 01, 2010 - Specifying the PICOTS (population, intervention, comparator, outcome, timing, and study design) characteristics … results (i.e., those that cannot be attributed in all likelihood to the intervention) from any study design … Serious flaws in study design or execution should be considered within and across studies; these flaws … Includes sample size, number of studies, and heterogeneity within or across studies. … questions concerning benefit Key: PICOTS=population, intervention, comparator, outcomes, timing, study design

364. Use of Observational Studies in Systematic Reviews of (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-observational-studies_methods.pdf
     June 01, 2010 - Specifying the PICOTS (population, intervention, comparator, outcome, timing, and study design) characteristics … results (i.e., those that cannot be attributed in all likelihood to the intervention) from any study design … Serious flaws in study design or execution should be considered within and across studies; these flaws … Includes sample size, number of studies, and heterogeneity within or across studies. … questions concerning benefit Key: PICOTS=population, intervention, comparator, outcomes, timing, study design

365. Comparative Effectiveness of Fecal DNA Testing in Screening for Colorectal Cancer in Average Risk Adults. (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-screening_disposition-comments.pdf
     February 01, 2012 - We understand the research design rationale for oversampling older adults. … We understand the research design rationale for oversampling older adults. … The next 1267 participants were part of a case-control study design in which the SDT-2 test was run … We understand the research design rationale for oversampling older adults. … We understand the research design rationale for oversampling older adults.

366. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cesarean-birth-2010_research-protocol.pdf
     January 01, 2010 - Published Online: May 6, 2011 Publication languages English only Admissible evidence (study design … measures, source of funding, stopping treatment early for benefit, and appropriateness of crossover design … publication, study location (e.g., country, city, state) and time period, population description, sample … size, and study type (e.g., RCT, prospective observational study, etc.). … Therefore study questions, design and/or methodological approaches do not necessarily represent the

367. EHC Research Protocol (Amended): Treatments for Acute Episodic Migraine (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-treatments-research-amended-protocol.pdf
     January 09, 2020 - • Original studies o RCTs o Comparative observational studies • Any sample size • Relevant systematic … Synthesis - We will qualitatively summarize key features/characteristics (e.g. study populations, design … Based on this assessment and the initial study design, we will assign SOE rating as high, moderate, … comparators), outcomes (e.g., use of unvalidated or nonstandardized outcomes), settings, and study design … Therefore study questions, design, and methodological approaches do not necessarily represent the views

368. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ischemic-stroke-treatment_executive.pdf
     January 01, 2011 - We included human studies of any design, case series, and case reports as long as they included patients … obtained the following information from each report: author identification, year of publication, study design … Compared to previous, similarly designed studies of these agents, these studies will enroll much larger sample … sizes (n=2,000 and 3,000, respectively). 10 The use of advanced imaging techniques should be incorporated … seem reasonable to conduct studies to answer such research gaps using a randomized controlled trial design

369. Web Interactive Presentation of EPC Reports: A Foray Into Interactive Reports (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-report-web-interactive-presentation.pdf
     September 01, 2019 - CMO’s office and partners with multidisciplinary teams of clinicians and administrators to identify, design … interventions, a summary of key characteristics of the underlying studies, including number of 5 arms, sample … size and risk of bias scores; and for interventions that have not been compared head to head, which … informative exhibits, including but not limited to, figures that show the number of studies, their design … (e.g., randomization unit, if applicable, number of arms, parallel or crossover), their sample size

370. celiac-disease-protocol-140612 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/celiac-disease_research-protocol.pdf
     June 12, 2014 - Inclusion / Exclusion Criteria Study design For KQ1a, we will include high quality systematic reviews … Study-level data abstracted will include: date study conducted; sample size; subjects’ demographic characteristics … (Yes/No/Unclear) Was a case-control design avoided? … Was an a priori study design provided? 02. … Studies will be weighted by sample size.

371. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-emergency_research-protocol.pdf
     July 18, 2011 - Inclusion criteria Study design Efficacy and effectiveness: RCTs and NRCTs. … The tables will include information on author, date of publication, study design, setting, treatment … groups, inclusion/exclusion criteria, sample size, study quality, and outcomes with effect sizes. … If the studies are homogenous with respect to design, population, intervention, and outcomes, results … Therefore study questions, design and/or methodological approaches do not necessarily represent the

372. Ptsd-Adults-Trauma-Interventions Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adults-trauma-interventions_executive.pdf
     April 01, 2013 - of a body of evidence, this approach incorporates four key domains: risk of bias (includes study design … Because the knowledge base comprises largely single studies with small sample sizes, we concluded that … assessed as high risk of bias have significant flaws of various types (stemming from serious errors in design … between-group differences at baseline) An important task of systematic reviews is to assess whether design … Investigators could also attempt to recruit sample sizes that provide sufficient power to detect prespecified

373. Primary Hypofractionated Radiation Therapy for Localized Prostate Cancer: Research Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypofractionated-radiation-therapy-protocol.pdf
     April 17, 2024 - NA Study Design KQs 1, 2. Randomized controlled trials KQs 3–5. Randomized controlled trials. … to be extracted will include general study information such as authors, year of publication, study design … the width of confidence intervals relative to a clinically important effect estimate, sufficiency of sample … size, and number of events. … Therefore, study questions, design, and methodological approaches do not necessarily represent

374. Breastfeeding and Health Outcomes for Infants and Children (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breastfeeding-health-outcomes-protocol.pdf
     February 01, 2023 - We will first triage full-text articles by outcome and according to study design (i.e., ESR or primary … or there is a signal that newer evidence might change the findings of the ESR (e.g., based on the design … primary studies, we will abstract general characteristics of the study (e.g., author, year, study design … the width of confidence intervals relative to a clinically important effect estimate, sufficiency of sample … size, and number of events.

375. Disposition of Comments Report for Interventions for Adult Offenders With Serious Mental Illness (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-adults-prisons_disposition-comments.pdf
     August 21, 2013 - power problems of individual studies as our goal is to conduct meta-analysis, making individual study sample … sizes irrelevant. … Commentator & Affiliation Section Comment Response specific strengths and weaknesses, such as sample … size, outcome measures, and fidelity assessment, etc. … It’s something you design a priori to guide the research, in which case, mortality should be part of

376. S29 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s29.pdf
     October 01, 2007 - Leaders’ views would be influenced by variations in study design and implementation. … Although CRTs generally require larger sample sizes than RCTs to achieve statistical power, the cost … not attend to critical analytic issues.19,20 Statistical guides need to be developed to facilitate sample … size calculation for regimens with various degrees of differ- ence in outcome, taking into account the … Design and Analysis of Cluster Randomization Trials in Health Research.

377. Disposition of Comments for Use of Natriuretic Peptide Measurement in the Management of Heart Failure (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-natriuretic-peptide_disposition-comments.pdf
     November 20, 2013 - These associations were confirmed as relevant during Discussions with experts during the design phase … As the reviewer states, results from NT-pro-BNP assays are, by design, similar which simplifies the … Rev 7 ES On KQ3 on page ES-11, the sample size are confusing. … Similarly, for morbidity outcomes on ES- 12, did the sample size refer to the number of studies? … The performance of tests of publication bias and other sample size effects in systematic reviews of

378. Medication-Therapy-Management Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/medication-therapy-management_executive.pdf
     November 01, 2014 - review), and precision of the evidence (degree of certainty surrounding an effect estimate based on sample … size and number of events). … Regardless of the goal of their future research, investigators should consider issues of sample size … time- series analysis, simulations, and factorial experiments) may permit both rigor and adequate sample … size within the context of real-world implementation.

379. Interventions To Prevent Age-Related Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer’s-Type Dementia (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cognitive-decline_executive.pdf
     March 01, 2017 - These included sample size, length of followup, measurement issues, and attrition. … no difference was difficult, especially when we were unable to use meta-analysis to address small sample … size issues. … Recommendations for Design and Methodology of Future Studies Future trials such as RCTs or pragmatic … While some researchers measured baseline cognitive function as part of the trial design, the degree

380. Interventions To Prevent Age-Related Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer’s-Type Dementia (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cognitive-decline_executive.pdf
     March 01, 2017 - These included sample size, length of followup, measurement issues, and attrition. … no difference was difficult, especially when we were unable to use meta-analysis to address small sample … size issues. … Recommendations for Design and Methodology of Future Studies Future trials such as RCTs or pragmatic … While some researchers measured baseline cognitive function as part of the trial design, the degree