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Total Results: 969 records

Showing results for "design sample size".

341. Disposition of Comments Report for Testing of CYP2C19 Variants and Platelet Reactivity for Guiding Antiplatelet Treatment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_disposition-comments.pdf
     September 25, 2013 - All types of blinding were assessed as applicable to each particular study design. … The low number of relevant studies, the inconsistencies in their design, analyses, and reporting, and … alleles and the linkage between them – joint statistical analysis is likely to require very large sample … sizes. … We agree that number of studies and sample size of each can affect the performance of heterogeneity

342. Untitled (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/tympanostomy-tubes_research-protocol.pdf
     November 16, 2015 -   7   Timing •   Any duration of followup Setting •   Primary and specialty care Study Design … exposures, and comparators) analyzed; outcome definitions; effect modifiers; enrolled and analyzed sample … sizes; study design features; funding source; results; and risk of bias questions. … These included descriptions of the study design, sample size intervention(s), followup duration, outcomes … Therefore study questions, design, and methodological approaches do not necessarily represent the views

343. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/treatment-resistant-depression_research-protocol.pdf
     December 09, 2009 - retrospective cohort studies for KQ 3 through KQ6 All treatment and followup durations and all sample … sizes will be accepted Studies of poor quality1 Single case reports or small case series Editorials … , study design, methods, and results. … A “poor” rating indicates significant bias (e.g., stemming from serious errors in design or analysis … Therefore study questions, design and/or methodological approaches do not necessarily represent the

344. Arthritis-Psoriatric Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-psoriatric_executive.pdf
     April 01, 2012 - Study eligibility (inclusion and exclusion) criteria were designed with respect to study design or duration … We included studies with sample sizes of at least 100 and duration of at least 3 months.

345. Towards a Framework for Communicating Confidence in Methodological Recommendations for Systematic Reviews and Meta-Analyses (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methodological-recommendations-framework-communications_research.pdf
     September 01, 2013 - meta-analysis of normally distributed data compared with other linear weighting schemes (e.g., by sample … size, or by inverse-standard error). … The ideal empirical study would use a paired design to compare the six alternative options in Table … The performance of tests of publication bias and other sample size effects in systematic reviews of … The design of simulation studies in medical statistics.

346. Research Protocol: Radiation Therapy for Brain Metastases (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/radiation-therapy-brain-metases-protocol.pdf
     October 10, 2019 - criteria in a PICOTSS (population, intervention, comparator, outcomes, timing, setting, and study design … settings such as developing countries will be reviewed for comparability with US settings Study design … manuscript, trial record), study status (e.g., early trial termination, preliminary data only), study design … Research Institute PICOTSS population, intervention, comparator, outcomes, timing, setting, study design … Therefore, study questions, design, and methodological approaches do not necessarily represent the views

347. FRN 22: Future Research Needs for Strategies To Reduce Cesarean Birth in Low-Risk Women (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cesarean-birth_research.pdf
     January 01, 2020 - Research Question Development and Research Design Considerations We did not have stakeholders rank … Design studies with pre-specified secondary outcomes and adequate power for these outcomes. 6. … o Design studies with prespecified secondary outcomes and adequate power for these outcomes. … Design studies with pre-specified secondary outcomes and adequate power for these outcomes. … Design studies with pre-specified secondary outcomes and adequate power for these outcomes. 6.

348. DST_Draft_Protocol_Nov_4_2013_clean (2) (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-decision-support-tools_research-protocol.pdf
     November 12, 2013 - Briefly, the key features of the developmental process include (1) scoping and design, (2) developing … We will require that trials have enrolled at least 10 subjects (per arm); smaller sample sizes are … for other effectiveness reviews and will include elements that address population characteristics, sample … size, study design, descriptions of the interventions and comparators of interest, analytic details … Design characteristics include methods of population selection and sampling and followup duration.

349. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c-treatment-adherence_research-protocol.pdf
     September 13, 2011 - study), whether the study randomized individual patients or clusters of patients, study setting, sample … size, geographic area of study, and number of study centers. … If a study is an RCT, we will also record the study design (i.e., parallel, crossover, and factorial … Generally, a good-quality study meets all criteria for that study design; a fair-quality study does … , sample size, study quality, patient characteristics, adherence interventions, controls, and outcomes

350. bipolar-disorder-treatment-protocol-140623 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/bipolar-disorder-treatment_research-protocol.pdf
     June 23, 2014 - Study Design and Quality Systematic reviews, RCTs, nonrandomized controlled trials, and prospective … catalogue one-off studies of interventions (only one study examining a particular intervention) with low sample … size. … Is the study design prospective, retrospective, or mixed? … Were the important confounding and effect modifying variables taken into account in the design and

351. Assessing Applicability (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/assessing-applicability.ppt
     January 01, 2009 - Experimental and quasi-experimental design for generalized causal inference. … size to assess minimally important differences from a patient perspective Use intention-to-treat analysis … duration and clinically relevant treatment modalities Assess for adverse events Have an adequate sample … size to assess minimally important differences from a patient perspective Use intention-to-treat analysis … Experimental and quasi-experimental design for generalized causal inference.

352. Evidence-based Practice Center Systematic Review Protocol: Prehospital Airway Management (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/prehospital-airway-management-protocol.pdf
     December 20, 2019 - Study Design: For all Key Questions, we will include randomized controlled trials (RCTs). … No studies will be excluded based on study design at this stage. … The criteria used will depend on the study design as recommended in the chapter, “Assessing the Risk … The results of these studies are at least as likely to reflect flaws in the study design as to show … , year, setting, country, sample size, eligibility criteria, population and clinical characteristics

353. Interventions for Breathlessness in Patients With Advanced Cancer: Evidence Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/dyspnea-advanced-cancer-summary-1.pdf
     November 01, 2020 - However, sample sizes were small, followup was short term, most studies only used visual analog scales

354. Future Research Needs for Noncyclic Chronic Pelvic Pain Therapies for Women (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/pelvic-pain-therapies-future_research.pdf
     January 01, 2015 - , equivalence, or noninferiority design, and a sample size calculation that accounts for the range of … Most trials (12/17) did report an a priori primary outcome of interest and sample size calculation. … Future research including larger sample sizes should yield greater confidence in treatment effects. … , equivalence, or noninferiority design, and a sample size calculation that accounts for the range of … Appropriate power/sample size for primary outcome and/or subgroup analyses 4.

355. Hepatitis-C-Screening Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-screening_executive.pdf
     November 01, 2012 - For studies of diagnostic accuracy, we created 2x2 tables from information provided (usually sample … size, prevalence, sensitivity, and specificity) and compared calculated measures of diagnostic accuracy … The results of these studies are judged to be at least as likely to reflect flaws in the study design … sizes and methodological shortcomings, including no unscreened comparison group. … sizes and long duration of followup.

356. Omega−3 Fatty Acids and Cardiovascular Disease: An Updated Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/fatty-acids-cardiovascular-disease_executive.pdf
     August 01, 2016 - However, factorial design (and other) studies that compared (for example) n-3 FA versus control, with … • Minimum sample sizes Due to the very large number of potentially eligible studies (more than 400 … ), we applied arbitrary thresholds based on sample size, followup duration, and whether subgroup or … � For RCTs with lipid outcomes without subgroup analyses, we included parallel design RCTs with … � We screened smaller sample size observational studies (starting with the largest studies) to include

357. App-D-Opioid-Chronic-Pain-Surveillance-Report-2 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveillance-report-2.xlsx
     September 30, 2015 - Randomized controlled trials Author, Year Study Design Duration Setting Country Eligibility Criteria … C: aOR 0.28 (95% CI 0.13 to 0.62) Note: ADL and IADL not calculated due to small sample size Patients

358. Omega-3 Fatty Acids and Maternal and Child Health: An Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/omega-3-maternity_executive.pdf
     October 01, 2016 - interest to RCTs of any size, and to prospective cohort studies and nested case control studies of sample … size 250 or greater (cross- sectional, retrospective cohort, and case study designs were excluded; … directness (of study outcome measures), and precision, as well as the number of studies by study design … Observational studies that enrolled fewer than 250 were excluded by design. … Future Research Recommendations The design of future RCTs should attempt to determine whether particular

359. Research White Paper Patient- or Participant-Generated Registries Addendum Registries for Evaluating Patient Outcomes Third Edition (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/patient-participant-generated-registries-guide-3rd-ed-addendum-white-paper.pdf
     February 01, 2018 - Moreover, PGRs may use any type of retrospective and/or prospective cohort study design used for other … meet the inclusion criteria for a planned trial, to assess the feasibility of enrolling the intended sample … size per protocol criteria, to determine desirable geographic locations of enrollment centers, and … Considerations The planning and design of a PGR may be a complex enterprise. … Patient-centeredness in the design of clinical trials. Value Health. 2014 Jun;17(4):471-5.

360. Disposition of Comments for Treatments for Fibromyalgia in Adult Subgroups (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/fibromyalgia_disposition-comments.pdf
     January 26, 2015 - sizes. … sizes) are not shown. … sizes) are not shown. … Sample size and related factors (such as attrition), are taken into consideration during different … Our write up provided key aspects of this study including patient inclusion criteria, study design,